Ayesha Medagedara

University of Colombo

Background: Pregnancy in a woman with lupus nephritis (LN) carries a high risk of maternal and fetal morbidity and mortality. This study aims to analyze the effect of LN on maternal and fetal outcomes and lupus activity.Methods: In a single-center, cross-sectional observational study at national hospital Kandy, 32 pregnancies in 23 women with biops...

Mortality in Chronic Kidney Disease of uncertain etiology (CKDu) is not well described despite being a major public health crisis in Sri Lanka. Data on CKDu have many gaps and published data on mortality are sparse. This retrospective descriptive study was designed to describe the mortality of CKDu in an endemic area. Deaths were identified by trac...

© 2022 Environmental Disease | Published by Wolters Kluwer - Medknow 47Comparison of biochemical characteristics between anendemic and a nonendemic area for CKDu Sri LankaA. Medagedara1,2, Pasan Hewavitharane1, Rohana Chandrajith3, Hemalika T. K. Abeysundara4,R. O. Thatil5, S. Thennakoon6, Buddhisha Mahanama1, N. Weerasuriya7, A. Thilakarathne7,Nis...

Background: The assessment of body fat distribution is an important evaluation in patients with lupus nephritis (LN), which does not practice routinely. The objectives of this study were to determine the body composition by using bioelectrical impedance analysis and to identify the effects of age, body mass index, disease activity, and corticostero...

Background: Chronic kidney disease of unknown etiology (CKDu) is a critical health issue among farming communities of the dry zone in Sri Lanka. Aims and Objectives: This study was conducted to identify the possible anthropological, biochemical, and geo‑environmental characteristics of CKDu, comparing an affected and nonaffected community. Material...

BACKGROUND AND AIMS Chronic kidney disease of unknown etiology (CKDu) has been a critical health issue among the farming communities of Sri Lanka for decades . However, the distribution of CKDu in Sri Lanka is geographically significant by representing endemicity on its own. This study was conducted to identify the anthropological and geo-environme...

Background: Haemodialysis (HD) patients are subjected to bio-psychosocial stress in many ways even after successful hemodialysis session. Therefore, this study was designed to survey on relationship between knowledge and treatment satisfaction with psychological well-being among haemodialysis patients. Methods: This cross-sectional study included...

Original Article

Introduction Systemic lupus erythematosus (SLE) disease activity index (SLEDAI) is utilized to assess the disease progression and to evaluate the clinical improvement following treatment. The study aims to evaluate and compare the disease activity in lupus nephritis (LN) patients on different immunosuppressive drug combination therapies. Methods Th...

Background

Adhering to multiple dietary recommendations may be difficult to follow but crucial in maintaining optimal nutritional status in patients on Continuous Ambulatory Peritoneal Dialysis (CAPD). Adherence to these recommendations requires patients to have a clear knowledge of the type, quality, and quantity of food they consume. Objectives were to asse...

Introduction and objectives- Anemia is a major consequence of chronic kidney disease. When severe, it is associated with many complications and even results in death. Anaemia is common among peritoneal dialysis patients and underlies many of the symptoms associated with reduced kidney function. Therefore, the aim of this study was to investigate th...

Introduction & Objectives: Alcohol consumption, smoking and betel chewing observed to be associated with chronic kidney disease unknown etiology (CKDu). Interestingly, some adverse health behaviors like betel chewing had been culturally accepted as a harmless practice. This study aimed to assess the prevalence of negative health behaviors among far...

Objectives: Absolute Iron Deficiency Anaemia (AIDA) occurs in absent or reduced iron stores in the body for erythropoiesis. In Functional Iron Deficiency Anaemia (FIDA), conventional biomarkers indicate adequate iron stores despite the low iron availability for erythropoiesis. Both types of iron deficiency anaemia (IDA) are common in hemodialysis (...

BACKGROUND AND AIMS: VitaminDdeficiency (VDD) isacommon, wellknown association in Chronic Kidney Disease (CKD). However, there are no published studies on theprevalence ofVDD among CKDu (Chronic Kidney Disease ofuncertain etiology) patients. This study aims to study on Vitamin Dstatus ofCKDu patients. METHOD: This was across sectionalsurveyconducted...

Background and Aims Vitamin D deficiency (VDD) is a common, well known association in Chronic Kidney Disease (CKD). However, there are no published studies on the prevalence of VDD among CKDu (Chronic Kidney Disease of uncertain etiology) patients. This study aims to study on Vitamin D status of CKDu patients. Method This was a cross sectional sur...

POS-129 BIOELECTRICAL IMPEDANCE ANALYSIS IN DETERMINING BODY COMPOSITION IN SRI LANKAN PATIENTS WITH LUPUS NEPHRITIS BASNAYAKE, D*1, Nayanamali, A1, Amarathunga, H2, Erandika, N1, Pathiraja, J2, Kandane-Rathnayake, R3, Wazil, A1, Nanayakkara, N1, Thennakoon, K1, Chathurani, I1, Deepani, R1, Wijayawickrama, B1 1National Hospital Kandy, Nephrology,...

Background: Satisfaction of treatment in patients on haemodialysis is determined by various factors and it has been recognized as foremost determinant of quality of life of patients. Moreover, it represents quality of comprehensive healthcare. Information on satisfaction regarding treatment in patients on haemodialysis was scarce. Objective: To ass...

Introduction and objectives -Anaemia is almost universal in advanced Chronic Kidney Disease (CKD) leading to poor quality of life, higher morbidity and mortality. Hence, multifaceted interdisciplinary care is required to prevent anaemia in Maintenance Haemodialysis (MHD). This study was conducted to identify the prevalence and risk factors of anaem...

Objectives: Pregnancy in a woman with lupus nephritis (LN) carries a high risk of maternal and fetal morbidity and mortality. Aim of this study is to analyze the effect of LN on maternal and fetal outcomes and lupus activity. Methods: In a single centre, cross sectional observational study at national hospital Kandy, 32 pregnancies in 23 women with...

Introduction: Chronic kidney disease of unknown ethology (CKDu) was first recognized in 1990s in Sri Lanka. Considering the distribution of CKDu in the country, endemic and non-endemic areas have been identified. This study was conducted to compare the biochemical profile between CKDu known endemic and non-endemic communities. Methods: A cross sec...

Introduction: Prevalence of Chronic kidney disease (CKD) depends on the abundance of risk factors in a community. Hence, Diabetic nephropathy, hypertensive renal diseases and vascular CKDs are common in the elderly population and immunological renal diseases are common in young people. There are some CKDs only localized to certain geographical area...

Introduction: Chronic kidney disease (CKD) is a major medical concern worldwide. Diabetes and hypertension are the most common causes for CKD. On the other hand, a new form of CKD has been identified without the risk factors like diabetic mellitus (DM) and hypertension (HTN). The present study was conducted to describe the prevalence of CKD in a ru...

Hemodialysis (HD) Patients' non-adherence to therapeutic recommendations and treatment satisfaction was determined by multidimensional factors and it has been recognized as foremost determinant of quality of life of a patient. Thus main purpose of this study was to assess the knowledge and treatment satisfaction of the patients undergoing HD treatm...

Background: Dyslipidemia and impaired glucose tolerance are common complications of chronic kidney disease (CKD) and are responsible for increased cardiovascular risk. Studies on lipid profile and glycemic status in CKD of unknown origin (CKDu) are scarce. The objective of this study was to evaluate the lipid profile and glycemic status of the pati...