Avneet Gupta

• Ph.D. in Pharmacy
• Principal at LR Institute of Pharmacy Solan

Objective: To develop and evaluate polymeric nanospheres of Carbimazole using Nano-precipitation method. Methods: The polymeric nanospheres of Carbimazole were prepared employing the nano-precipitation method using a varied concentration of Chitosan (polymer). The prepared formulations were characterized for several parameters such as SEM, Particle...

Recent advancements in nanotechnology have resulted in improved medicine delivery to the target site. Nanosponges are three-dimensional drug delivery systems that are nanoscale in size and created by cross-linking polymers. The introduction of Nanosponges has been a significant step toward overcoming issues such as drug toxicity, low bioavailabilit...

Background and Objective Bacopa monnieri, Evolvulus alsinoides, and Tinospora cordifolia are well known herbal Ayurvedic medicinal plants with a memory enhancing property. The aim of this study was HPTLC analysis for evaluating the effect of ethanolic extract of Bacopa monnieri (BME), Evolvulus alsinoides (EAE) and Tinospora cordifolia (TCE) alone...

Background Diabetic wound are the major problem of society because of its delay healing of wound in hyperglycemia patient. The target of this study need to know the gallic acid compelling synergistically wound healing in diabetic animals as it is available in fruit extract or is more effective in given pure form in diabetic animals. Methods The wo...

Aim The study aimed to evaluate the anti-arthritic potential of ethanolic extract of Cissampelos pareira (Menispermaceae) and Stephania glabra (Menispermaceae). Methods Sprague Dawley rats (200 ± 20g) were used as experimental animals. Animal models like Freund’s Adjuvant (FA) induced inflammation, Monosodium Iodo Acetate (MIA) induced osteoarthri...

Background: Woodfordia fructicosa is used traditionally for the treatment of inflammation associated with arthritis. Material and method: In the present study, the anti-inflammatory activity of W. fructicosa (WFE) leaves ethanolic extract was assessed in Sprague Dawley rats by giving 200 mg/kg dose orally. Inflammation was studied by using carra...

The aim of this work is to evaluate the qualitative HPLC-analysis of Gallic acid in chloroform, methanolic and ethanolic extracts of Terminalia bellerica plant fruit. The chromatographic conditions used for the qualitatively examination of Gallic acid in chloroform, methanolic and ethanolic plant fruit extracts were performed on a Shimadzu LC-20AT,...

Gallic acid is a naturally occurring polyphenolic compound found in processed beverages such as red wines and green teas. It occurs in plants in the form of free acids, esters, catechin derivatives and hydrolysable tannins. The interest in these compounds is due to its pharmacological activity as radical scavengers. It has been proved to have poten...

Aim: Bacopa monnieri, Evolvulus alsinoides and Tinospora cordifolia are the important ayurvedic medicine belonging to family Scrophulariaceae, Convolvulaceae and Menipermaceae. These are the traditionally used medicine and possess important medicinal properties. The physicochemical standardization is very important for the valuable relevance of the...

Learning is defined as the acquisition of information and skills and subsequent retention of the information is called memory. Dementia is one of the ages related mental problems and characteristic symptom of various neurodegenerative disorders including Alzheimer's disease which is age related. It is a progressive and neurodegenerative disorder. T...

Terminalia bellerica is an important traditional Indian medicinal plant used in various ailments and rituals. The use of different parts of this plant like leaves and fruits as a medicament for treatment of various conditions is well documented in literature. Terminalia bellerica Roxb. (Combretaceae) is one of the ingredients of ayurvedic purgative...

Terminalia bellerica is an important traditional Indian medicinal plant used in various ailments and rituals. The use of different parts of this plant like leaves and fruits as a medicament for treatment of various conditions is well documented in literature. However, the studies on phytochemical constituents and medicinal properties in the fruit o...

HIV/AIDS has always been one of the most thoroughly global of diseases. The human immunodeficiency virus (HIV) is a lent virus that causes HIV infection and AIDS. AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening infections and cancers to thrive. Infection with HIV occurs by the transfer of bloo...

A peptic ulcer is a sore on the lining of the stomach or duodenum. The two most common types of peptic ulcer are called gastric ulcers and duodenal ulcers. Peptic ulcers are found to be due to an imbalance between aggressive factors such as hydrochloric acid (HCL), pepsin, refluxed bile, leukotrienes (LTs), reactive oxygen species (ROS) and defensi...

Plants has ever been an important part of human life in different ways. Number of herbals has been listed for their medicinal and cosmetics values. We can never miss out their role in the treatment of several diseases. Moreover, the plant based medicines has also being used for untreatable disease as there is no other option except them. Researcher...

Bacopa monnieri, Evolvulus alsinoides and Tinospora cordifolia are established ayurvedic herbs having neuropharmacological effect. In present study is aimed to Phytochemical Comparison between Pet ether and Ethanolic extracts of Bacopa monnieri (BME), Evolvulus alsinoides (EAE) and Tinospora cordifolia (TCE). To identify the presence (+) or absence...

Present investigation was performed on Albino wistar rats. The effect of ethanolic extracts of whole plants of Bacopa monnieri (BME), Evolvulus alsinoides (EAE), Tinospora cordifolia (TCE) and their combinations of equal proportion [CEP-1 (BME+EAE), CEP-2 (BME+TCE), CEP-3 (EAE+TCE) and CEP-4 (BME+EAE+TCE)] were tested in amnesic rats using Radial a...

Bacteria are meant to be omnipresent and are mostly involved in lots of human microbial infections. Such bacterial infections can be identified by the different properties of this microorganism. Bacteria are bearing several inherent properties. by using these properties we can differentiate, can check there presence and absence, can check their gra...

In the present study we have reviewed the synthesis and different biological activities of some Schiff bases of imidazo-[2, 1b]-1, 3, 4-thiadiazole derivatives. The Schiff base is functional group that contains a carbon- nitrogen double bond with nitrogen atom connected to an aryl or alkyl group but not hydrogen. Schiff bases can be synthesized fro...

Indisputably the third millennium is witnessing the worldwide changes in healthcare. Ayurvedic system of healthcare has gained good popularity. Ayurveda is a profound and comprehensive system of health care that originated in India. This system endeavors to rationalize the all phenomena governing empirical experiences with natural products in medic...

Stomach-specific mucoadhesive microspheres as a controlled drug delivery system have been developed to increase gastric retention time of the dosage forms. This article presents the polymers use for mucoadhesive microspheres, factor affecting the mucoadhesion, and developments in the techniques for in vitro and in vivo evaluation of mucoadhesive mi...

Tuberculosis is today amongst the worldwide health threats. As resistant strains of Mycobacterium tuberculosis have slowly emerged, the failure of treatment is too often a fact, especially in countries lacking the necessary health care organization to provide the long and costly treatment have adapted by the patients. Because of lack of treatment o...

Various animal models have played a major role in the history of modern drug development for memory. Models for Alzheimer's disease complement human investigations to study in detail pathogenic hypothesis and therapeutic strategies. To achieve this several new models have been produced. Various methods have been applied to induce in animals experim...

Ayurveda is a profound and comprehensive system of health care that originated in India. This system endeavors to rationalize the all phenomena governing empirical experiences with natural products in medicine. Ayurvedic medicinal plants are validated with a view to bring their usage in the main stream. Ayurvedic medicare system has attained popula...

By considering the importance of essential oils for good hale and health of mankind in recent time, present study is focused on hydrodistillation of Stephania glabra (SG) and Woodfordia fruticosa (WF). Volatile oils of the SG tubers and WF leaves were obtained by hydrodistillation by using clevenger apparatus (lighter than water).Thin layer chromat...

Physicochemical evaluation is the parameters to evaluate the presence of inorganic ion fraction in the drug whereas the phytochemical screening enables to find out the presence of total phytoconstituents in the drug material. Both Physicochemical and Phytochemical evaluation are use to evaluate the drug by comparing it with the standard parameters....