Augustinas Matulevičius

• PhD
• Urologist at Vilnius University Hospital Santariškių Klinikos

This study aimed to investigate the extent of field cancerization adjacent to index lesions in prostate cancer (PCa) by measuring DNA methylation of selected tumor suppressor genes in the perifocal tissue of PCa not visible on multiparametric magnetic resonanse imaging (mpMRI) for the safe zone of focal therapy identification.

Background and Objectives: Germline DNA damage response (DDR) gene mutations correlate with increased prostate cancer (PCa) risk and a more aggressive form of the disease. DDR mutation testing is recommended for metastatic PCa cases, while eligible information about the mutations’ burden in the early-stage localized PCa is still limited. This study...

On June, 2023, Vilnius University Hospital Santaros Klinikos started robotic-assisted operations using VERSIUS robotic surgery system (CMR, Cambridge, UK) and performed 29 robotic surgeries within the first 3 weeks. This surgical system was purchased with funding from the European Regional Development Fund. Comprehensive three-month-long learning c...

Background: This study aimed to investigate the extent of field cancerization adjacent to index lesions in prostate cancer (PCa) by measuring DNA methylation of selected tumor suppressor genes in the perifocal tissue of PCa not visible on multiparametric magnetic resonanse imaging (mpMRI) for the safe zone of focal therapy identification. Methods...

The primary objective of this study was to demonstrate the high accuracy of multiparametric magnetic resonance imaging and ultrasound fusion (mpMRI/US)-guided targeted prostate biopsy for the detection of clinically significant prostate cancer (PCa) and to show that adapted systematic biopsy (AdSB) does not provide additional benefit in detecting c...

Introduction: Midurethral tape implantation procedures currently are the first-line treatment for female stress urinary incontinence (SUI). Aim: To estimate the most common intraoperative and postoperative complications and their treatment methods after midurethral tape implantation using retropubic (tension-free vaginal tape - TVT) and transobt...

Key words: invasive upper tract urothelial carcinoma, radical nephroureterectomy, chemotherapy treatment. Based on literature sources Urothelial carcinomas (UCs) are the fourth most common tumors. They can be located in the lower (bladder and urethra) or upper (pyelocaliceal cavities and ureter) urinary tract. Herein, we report a rare case of upper...

Reikšminiai žodžiai: vyrų šlapimo nelaikymas, dirbtinis šlapimo pūslės sfinkteris, radikali prostatektomija, ZSI 375. Darbo tikslas. Pateikti pirmuosius vyrų šlapimo nelaikymo po radikalios prostatektomijos rezultatus, implantuojant ZSI 375 dirbtinį sfinkterį. Įvertinti šio metodo efektyvumą ir pranašumą. Medžiaga ir metodai. 2013–2014 m. VUL SK Ur...

Reikšminiai žodžiai: įtampos tipo šlapimo nelaikymas, nutukimas, pošlapliniai raiščiai. Tikslas. Nustatyti, kokios dažniausios įtampos tipo šlapimo nelaikymą sukeliančios priežastys moterims, kokios dažniausios pooperacinės komplikacijos, išsiaiškinti, ar nutukimas ir antsvoris lemia ligonių, operuotų dėl šlapimo nelaikymo fizinio krūvio metu impla...

Reikšminiai žodžiai: įgimtas varpos kreivumas, varpos plastika, chirurginis gydymas. Tikslas. Šio darbo tikslas yra apibendrinti įgimto varpos kreivumo chirurginio gydymo pagal Nesbito rezultatus Vilniaus universiteto ligoninės Santariškių klinikų Urologijos centre. Medžiaga ir metodai. Nuo 1999 iki 2014 metų, Vilniaus universiteto ligoninės Santar...