Atif Khurshid Wani

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Verified

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• Ph.D Biotechnology
• Researcher at Lovely Professional University

Insects, with their vast biodiversity and essential ecological roles, are crucial to agriculture, textile production, and environmental stability. As pollinators, decomposers, and bioindicators, they support ecosystem functions and human industries. Their short generation time, high reproductive rates, and genetic adaptability make them valuable mo...

The escalating global demand for clean, sustainable energy has catalyzed the exploration of renewable feedstocks, with plant biomass emerging as a pivotal resource in the transition to a low-carbon bioeconomy. This review synthesizes recent advancements in biomass conversion technologies, focusing on the integration of thermochemical and biochemica...

In modern society, the use of computational modeling has increased significantly in a variety of industries. This increase is especially noticeable because of growing concerns about the rapid depletion of fossil fuels and their harmful effects on the environment. As a result, there has been a lot of interest in researching alternative energy source...

The pandemic of COVID-19 has ignited a global race to locate effective therapies with drug repositioning emerging as a leading strategy due to its cost-effectiveness and established safety profiles. Remdesivir, Favipiravir, Hydroxychloroquine, and Chloroquine have been the focus of rigorous clinical trials to determine their therapeutic potential a...

Microalgae, which include over 30,000 different species, are an incredibly rich source of nutrients and health-boosting compounds. They have shown impressive health benefits due to their antioxidant, anti-inflammatory, antimicrobial, and anticancer properties, making them valuable for developing medicines, functional foods, and dietary supplements....

Biogeochemical cycles are fundamental processes that regulate the flow of essential elements such as carbon, nitrogen, and phosphorus, sustaining ecosystem productivity and global biogeochemical equilibrium. These cycles are intricately influenced by plant-microbe symbioses, which facilitate nutrient acquisition, organic matter decomposition, and t...

Gymnema sylvestre (Retz.) R.Br. ex Sm., is a perennial woody climber of Apocynaceae family. It is native to Asia, Africa, Australia, and some parts of Arabian Peninsula. This is an important medicinal herb commonly used in various traditional medicinal systems to treat diabetes mellitus (DM). Plant parts of G. sylvestre have wide array of phytochem...

Textile dyes pose a major environmental threat due to their toxicity, persistence in water bodies, and resistance to conventional wastewater treatment. To address this, researchers have explored biological and physicochemical degradation methods, focusing on microbial, photolytic, and nanoparticle-mediated approaches, among others. Microbial degrad...

Plants possess the remarkable ability to thrive in challenging environments by synthesizing a diverse array of specialized metabolites, which play crucial roles in defense against biotic and abiotic stresses. Despite their significance, the low natural yield of these bioactive compounds, coupled with genetic variability and environmental influences...

Recent years have seen a significant increase in microplastic contamination across terrestrial ecosystems, facilitated by various pathways such as atmospheric deposition, wastewater irrigation, and agricultural plastic mulching. This persistence of microplastics in soil raises concerns about their profound impacts on soil health and ecosystem dynam...

Non-coding RNAs have gathered significant attention for their unique roles in biological regulation. Across a broad spectrum of developmental processes and diseases, particularly in human malignancies, ncRNAs play pivotal roles in regulatory mechanisms. MicroRNAs, long noncoding RNAs, and small nucleolar RNAs stand out among the diverse forms of nc...

Food packaging is critical in assuring product safety, ease of handling, and shelf life extension, all contributing to increased consumer convenience. Packaging made from various materials, including plastics, glass, metals, papers, and composites, must also address growing health concerns about the possible migration of hazardous substances into f...

Glutathione (GSH) is a critical tripeptide composed of glutamate, cysteine, and glycine, playing a multifaceted role in plant physiology, especially under stress conditions. As a powerful antioxidant, GSH is essential for maintaining cellular redox balance, which is crucial in protecting plants from oxidative damage. This molecule is deeply involve...

Automation, autonomy, and precision play vital roles in modern technology and procedures, especially in response to the rising global population and the need for improved fruit production technologies. The quality criteria for fruit yield are becoming increasingly complex, necessitating fundamental upgrades. Sensor-based technologies pave the way f...

Plant metabolism is a complex network of biochemical reactions that regulate various physiological and developmental processes in plants. Abiotic stress, such as drought, salinity, temperature extremes, and nutrient deficiency, can significantly affect plant metabolism and productivity, leading to reduced crop yields. The response of plants to abio...

Rhizosphere is a dynamic and complex environment shaped by intricate interactions between plants and a diverse microbial community. The rhizosphere microbiome is crucial for plant growth, nutrition, and health in agro-ecosystems. Recent advancements in metagenomics, especially through shotgun sequencing, offer unprecedented opportunities to unravel...

Background and Objectives: Cervical cancer global burden is highly skewed towards poor countries primarily due to lack of awareness, poor screening, and low uptake of prophylactic vaccines. The purpose of our study is to educate and raise awareness among young girls and women about the importance of cervical screening and HPV vaccination. Materials...

This study explored the metagenome of the Pir Panjal Hot Spring (PPHS) to identify thermostable hydrolases. The carboxypeptidase (CarP) gene was successfully amplified and cloned into Escherichia coli DH5-α cells, followed by expression in E. coli BL21-DE3 cells. The CarP enzyme was comprehensively characterized in vitro. Sequencing analysis reveal...

Lipid-based vectors are becoming promising alternatives to traditional therapies over the last 2 decades specially for managing life-threatening diseases like cancer. Cationic lipids are the most prevalent non-viral vectors utilized in gene delivery. The increasing number of clinical trials about lipoplex-based gene therapy demonstrates their poten...

In biotechnological methods for biodegradation, the effectiveness of detoxifying xenobiotics and recalcitrant substances in soil and water has sparked significant interest. Our study takes a unique approach by focusing on immobilizing the white-rot fungus (WRF) Pleurotus sajor-caju onto a Luffa cylindrica plant support. This innovative method aims...

The emergence of plastic waste from industries is a serious ecological concern. In recent years, plastic has been identified in various ecosystems, including human tissues, posing a threat to the biotic components of the Earth and giving rise to potential adverse consequences. The plastic waste is fragmented into smaller components like nanoplastic...

Hydrothermal sources are of paramount importance for the exploration of small molecules carrying important biochemical and genetic information. They harbor thermophilic microbial communities that are useful in developing commercially useful products for pharmaceutical, agriculture, cosmetics or aquaculture industries. South Asian countries are rich...

Carbon nanotubes (CNTs) have emerged as a promising frontier in plant science owing to their unique physicochemical properties and versatile applications. CNTs enhance stress tolerance by improving water dynamics and nutrient uptake and activating defence mechanisms against abiotic and biotic stresses. They can be taken up by roots and translocated...

Microbial exopolysaccharides (EPSs) have emerged as a fascinating area of research in the field of pharmacology due to their diverse and potent biological activities. This review paper aims to provide a comprehensive overview of the pharmacological properties exhibited by EPSs, shedding light on their potential applications in various therapeutic a...

Pineapple (Ananas comosus), the succulent and vibrant tropical fruit, is a symbol of exoticism and sweetness that captures the hearts and palates of people around the world. The pineapple peel, often considered as waste, has garnered attention for its potential applications. The pineapple peel is rich in essential nutrients, including calcium, pota...

Climate change emerges as the most dynamic and pervasive environmental challenge of the contemporary era. Its consequences, including the greenhouse effect resulting in elevated temperatures, increasingly frequent droughts, and unpredictable rainfall patterns, are already evident. The effects of climate change and extreme weather phenomena encompas...

Antibiotic pollution poses a potential risk of genotoxicity, as antibiotics released into the environment can induce DNA damage and mutagenesis in various organisms. This pollution, stemming from pharmaceutical manufacturing, agriculture, and improper disposal, can disrupt aquatic ecosystems and potentially impact human health through the consumpti...

The rapid rise of artificial intelligence (AI) technology has revolutionized numerous fields, with its applications spanning finance, engineering, healthcare, and more. In recent years, AI's potential in addressing environmental concerns has garnered significant attention. This review paper provides a comprehensive exploration of the impact that AI...

Rare cancers (RCs), which account for over 20% of cancer cases, face significant research and treatment challenges due to their limited prevalence. This results in suboptimal outcomes compared to more common malignancies. Rare bone tumors (RBTs) constitute 5–10% of rare cancer cases and pose unique diagnostic complexities. The therapeutic potential...

Sarcoma is a heterogeneous group of malignancies often resistant to conventional chemotherapy and radiation therapy. The phosphatidylinositol-3-kinase/ protein kinase B /mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathway has emerged as a critical cancer target due to its central role in regulating key cellular processes such as cell gr...

Next-generation sequencing (NGS) concepts involve the way and manner to obtain the primary structure of either the nucleic acids or the proteins, or both, from the organisms in question through the applications of Sanger sequencing, Roche 454 (Pyrosequencing), Illumina, Ion Torrent, ABI SOLiD, PacBio, Helicos, and Oxford Nanopore Technology. The in...

Food packaging refers to any materials that are used to shield a product against physical, chemical, and biotic factors, which leads to food contamination. The packaging materials (PMs) are not inert; they interact with food constituents and can alter the food quality. The food–packaging interaction can result in the migration of unhealthy componen...

Background and Objectives Rinaie Marwah hot spring Kishtwar (RMHSK) is one of the geothermal springs located at 33°51′51″N 75°32′07″E with an elevation of 2134 meters above sea level in Jammu and Kashmir, India. We aimed to study the microbial diversity of this geothermal spring using metagenomics. Materials and Methods In the present study, physi...

The human microbiome is vital for maintaining human health and has garnered substantial attention in recent years, particularly in the context of the coronavirus disease 2019 (COVID-19) outbreak. Studies have underscored significant alterations in the microbiome of COVID-19 patients across various body niches, including the gut, respiratory tract,...

The effects of the gut microbiome on the brain and the mechanisms of gut-brain communication have been popular research topics for the past few decades. The term gut-brain axis (GBA) evolved to illustrate how the gut and gut microbiota communicate with the brain. The gut-brain axis is an interplay of the neural, endocrine, immune, and metabolic pat...

The aim of the present study is to utilize bibliometric analytical tools to examine the trends in research publications within the hot spring metagenomics field. To achieve this, an in-depth exploration of the Scopus and Web of Science (WoS) databases was undertaken to recognize scholarly articles within this research domain that were published fro...

Portable biosensors are emerged as powerful diagnostic tools for analyzing intricately complex biological samples. These biosensors offer sensitive detection capabilities by utilizing biomolecules such as proteins, nucleic acids, microbes or microbial products, antibodies, and enzymes. Their speed, accuracy, stability, specificity, and low cost mak...

Existing therapeutic interventions for controlling cancer are limited and associated with side effects. Furthermore, the recurrence of cancer poses a significant challenge to the cure of cancer. Therefore, avenues are wanted to find novel therapies for cancer treatment and cancer recurrence. In this review, we have highlighted that lactoferrin (LF)...

Ivermectin (IVM), an antiparasitic drug, has a wide range of biological applications. Taking its spectrum of actions into consideration along with the significant safety and efficacy it was approved by USFDA in 2015 and made available as a generic medicine. In addition to cancer, it is used to treat number of bacterial and viral infections in human...

Ripening of fruit is a complex physiological process comprising a sequence of events that precipitates the signaling molecules, especially hydrogen peroxide (H2O2), ethylene, melatonin, nitric oxide (NO), auxin, hydrogen sulfide (H2S), and brassinosteroids at different levels of gene and protein expression to initiate activation and/or deactivation...

The physiological process of ripening occurs rapidly when fruits and vegetables become mature, and beyond a specific stage after the harvest, they to undergo rapid deterioration in quality. Melatonin, a nontoxic biological molecule with significant antioxidant capacity, plays several roles, including delaying senescence, alleviating chilling injury...

Drought stress negatively affects the physiology, biochemistry, and morphology of plants. This leads to leaf rolling, leaf scorching, stunning plants, and permanent wilting. Plants adapt different strategies to build stress tolerance by enhancing the production of certain phytohormones. Melatonin is synthesized in plants in response to biotic and a...

Background: AKT1 is a serine/threonine kinase necessary for the mediation of apoptosis, angiogenesis, metabolism, and cell proliferation in both normal and cancerous cells. The mutations in the AKT1 gene have been associated with different types of cancer. Further, the AKT1 gene mutations are also reported to be associated with other diseases such...

Plants respond to a range of abiotic stimuli in nature involving anatomical, cellular, morphological, and physiological changes. The adaptability of plants to acclimatize to different environments is greatly influenced by phytohormones, which mediate growth, development and nutrient partitioning. These signal molecules are biosynthesized by plant i...

The use of NPs is expanding across a wide range of industries. Human exposure to NPs, intentionally or accidently, is unavoidable due to their extensive use in several fields. NPs are constantly exposed to people, and it is crucial to understand the possible acute and long-term detrimental impacts they may have. NMs can pass biological barriers and...

The seafood industry generates waste, including shells, bones, intestines, and wastewater. The discards are nutrient-rich, containing varying concentrations of carotenoids, proteins, chitin, and other minerals. Thus, it is imperative to subject seafood waste, including shrimp waste (SW), to secondary processing and valorization for demineralization...

Biofuel has been the center of attention across the world due to its potential as an ecofriendly fuel. Microalgae is known for its biofuel generation owing to its growth rate, economical culture approaches, rich energy content, CO2 fixation capacity, and O2 addition to environment. The cascade of biofuel production involves mass production, harvest...

Catalase, an antioxidant, is predominant in living organisms dwelling in oxygen-rich environments. From simple microorganisms to plants and animals, it is crucial in bestowing cell protection when exposed to oxidative stress. Hydrogen peroxide, a common subversive byproduct of metabolism, is acted upon by catalase catalyzing its decomposition proce...

The current study aims to investigate the research publication trends in the field of forensic genetics using Bibliometric analysis. An extensive search of the Scopus database was conducted to identify scholarly articles on forensic genetics published between 1977 and 2022, and a data set comprising 2945 articles was obtained. The analysis was carr...

Sugarcane is a tall, stout, perennial grass with fibrous stalks rich in sucrose used for sugar production. Sugarcane is widely used to produce sugar, ethanol, and other bioactive compounds. However, the processing of sugarcane and its byproduct bagasse can result in negative environmental impacts and safety hazards. Therefore, safe, and sustainable...

Candida dubliniensis is an opportunistic pathogen associated with oral and invasive fungal infections in immune-compromised individuals. Furthermore, the emergence of C. dubliniensis antifungal drug resistance could exacerbate its treatment. Hence, in this study a multi-epitope vaccine candidate has been designed using an immunoinformatics approach...

Apoptosis is the elimination of functionally non-essential, neoplastic, and infected cells via the mitochondrial pathway or death receptor pathway. The process of apoptosis is highly regulated through membrane channels and apoptogenic proteins. Apoptosis maintains cellular balance within the human body through cell cycle progression. Loss of apopto...

Microplastics (MPs) are ubiquitous pollutants persisting almost everywhere in the environment. With the increase in anthropogenic activities, MP accumulation is increasing enormously in aquatic, marine, and terrestrial ecosystems. Owing to the slow degradation of plastics, MPs show an increased biomagnification probability of persistent, bioaccumul...

Bioterrorism is the intentional dissemination of bio-warfare agents in a population to cause illness or death. Microbial forensics plays an essential role in the investigation of bio-terror attacks. This is a new field of forensic science that is still in the early stages of growth and faces huge theoretical and ethical obstacles. There is a profou...

Monkeypox is a self-limiting zoonotic viral disease and causes smallpox-like symptoms. The disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the disease has occurred. The currently available vaccines that have provided immunization against monkeypox are classified as live attenuated vaccinia virus-based vaccines,...

Circular RNAs (circRNAs) are a recently identified class of RNAs produced via back-splicing and covalent linkage between RNA ends, resulting in a circularized RNA molecule. Physiologically, circRNAs are known to influence a variety of biological pathways, and can also regulate transcription, post-transcription, RNA splicing, or interaction with oth...

Exosomes (EXOs) are naturally occurring tiny extracellular nanovesicles, which emancipate into the extracellular environment by exocytosis. By moving vital biological molecules (DNA, mRNA proteins, etc), EXOs contribute to intercellular communications. Camel milk (CM) as a valuable food, is rich of EXO. Nowadays, EXOs are promising delivery agents...

Microorganisms dwell in diverse plant niches as non-axenic biotic components that are beneficial as well pathogenic for the host. They improve nutrients-uptake, stress tolerance, phytohormone synthesis, and strengthening the defense system through phyllosphere, rhizosphere, and endosphere. The negative consequences of the microbial communities are...

Metagenomics and other omics approaches have unfolded diverse fields concomitant with the microbial microcosm. With increasing anthropogenic activities, population density, and industrialization, contaminants of distinct chemical nature have also escalated. Therefore, degradation of contaminants has become necessary because of the prolonged persist...

Intramuscular fat (IMF) content is a crucial determinant of meat quality traits in livestock. A network of transcription factors act in concert to regulate adipocyte formation and differentiation, which in turn influences intramuscular fat. Several genes and associated transcription factors have been reported to influence lipogenesis and adipogenes...

Since December 2019 SARS-CoV-2 infections have affected millions of people worldwide. Along with the increasing number of COVID-19 patients, the number of cases of opportunistic fungal infections among the COVID-19 patients is also increasing. There have been reports of the cases of aspergillosis and candidiasis in the COVID-19 patients. The COVID-...

Livestock is an essential life commodity in modern agriculture involving breeding and maintenance. The farming practices have evolved mainly over the last century for commercial outputs, animal welfare, environment friendliness, and public health. Modifying genetic makeup of livestock has been proposed as an effective tool to create farmed animals...

Saffron, a Crocus sativus L. derivative, has been recognized for its medical benefits since ancient times. Besides being an active flavoring and coloring agent in several food items, saffron has primarily been known for its pharmacological properties. Its major metabolites like crocin, picrocrocin, and safranal have been studied in vivo and in vitr...

To Indonesia is one of the countries with a long history of Kenaf fiber cultivation besides the US, Bangladesh, India, Thailand, and Australia. Retting is the main challenge faced during the processing of bast plants for the production of long fiber. The traditional method of separating the long bast fibers involves a water retting process for abou...

Saffron, a dried stigma derivative of Crocus sativus, is tremendously rich in phytochemicals like crocin and safranal. For a long time, the phytochemicals of saffron have remained obscure, therefore its role in disease treatment remained subsidiary. Of late, researchers have gained momentum in studying its bioactivity because of its numerous health...

Dark septate endophytes (DSE) exert a plethora of effects in regulating plant growth, signalling and stress tolerance. The advent of metagenomics has led to the identification of various species of DSE to be associated with plant organs. They are known to modulate growth, nutrient uptake, phytohormone biosynthesis and production of active biocons...

Background Cancer, an uncontrolled multistage process causing swift division of cells, is a leading disease with the highest mortality rate. Cellular heterogeneity, evading growth suppressors, resisting cell death, and replicative immortality drive the tumor progression by resisting therapeutic action of existing anticancer drugs through a series o...

With the enormous increase in population and industrial network, the harmful pollutants affecting biota have also escalated. The pollutants are consumed by living organisms directly or indirectly reducing animal and economic wellbeing. The degradation of contaminants is imperative owing to the prolonged persistence of contaminants like plastics, he...

The present device is detachable and can be attached to any cordless phone, the device has a cleaning module that is having UV rays for sanitization, IR for touch sensors. The cleaning module does time-based sanitization. The device is solar battery operated so consumes a minimum amount of energy. The device is cost-effective and easy to use.

Citrus rinds contain essential oils. One of the major constituents of the essential oils in the zest of different fruits like Citrus sinensis, C. limon, and Vitis vinifera is limonene. In this research, limonene was extracted by hydro-distillation method using Clevenger set up and its antimicrobial activity against certain bacterial and fungal stra...

The association of microorganisms with livestock as endosymbionts, opportunists, and pathogens has been a matter of debate for a long time. Several livestock-associated bacterial and other microbial species have been identified and characterized through traditional culture-dependent genomic approaches. However, it is imperative to understand the co...

Human microbiome is ubiquitous, dynamic, and site-specific consortia of microbial communities. The pathogenic nature of microorganisms within human tissues has led to an increase in microbial studies. Characterization of genera, like Streptococcus, Cutibacterium, Staphylococcus, Bifidobacterium, Lactococcus and Lactobacillus through culture-depende...

For many years, scientists have aspired to edit any DNA segment of living organisms precisely, and with the discovery of CRISPR/Cas9, they have moved closer to achieving their objective. Using this tool, researchers can knock out or knock-in a gene into or from any part of the genome. The CRISPR–Cas9 system is a highly effective and accurate tool a...

Microorganisms are ubiquitous on Earth and can inhabit almost every environment. In a complex heterogeneous environment or in face of ecological disturbance, the microbes adjust to fluctuating environmental conditions through a cascade of cellular and molecular systems. Their habitats differ from cold microcosms of Antarctica to the geothermal volc...

Globally, there is a growing demand for biocatalysts because of the associated efficacy and efficiency. The applications of enzymes in food, paper, pulp, textile, and chemical industries have prompted enzyme exploration. Microbes, being the natural reservoirs of enzymes, have gained researchers’ attention, and the quest for microbial enzymes has in...

Depression: When Death Seems Purposeful “WHY” is perhaps the most annoying sound that a disturbed mind can’t live with I can’t eat, I can’t sleep, I can’t focus………I’m not doing well- This is the story of every you and me. From old “Suli Kak” to today’s “John sab”, From every “Bobhi” to someone’s “Pari”, everyone is lost in space, disconnected from...

Climate change covers super colossal shifts in the weather patterns having bizarre impact on the Earth and its dwellers. The main lead foot in climatic shifts is the global warming driven by the enormous emissions of carbon dioxide and methane. Humans continue to play a foul sport by large-scale fossil fuel burning, agricultural activities,deforest...