Ateeq Al-Zahrani

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• PhD
• Associate Professor at Umm al-Qura University

Ficus platyphylla is a deciduous species that has long been regarded for its medicinal benefits. Different components of the plant, such as the leaves, stem, bark, and roots, are utilized in the treatment of conditions including psychosis, inflammation, epilepsy, and depression. Pathogenic bacteria in the modern world are constantly developing resi...

The growing interest in health-promoting food options has highlighted the need to explore new sources with unique nutritional compositions. Plants are rich sources of bioactive compounds with biological effects. Urelytrum giganteum Pilg is a perennial wild tufted grass that grows in dry tropical African countries. Traditionally, it has been used to...

Purpose: Adansonia digitata L. is a highly esteemed and versatile tree native to Africa. It offers numerous benefits in terms of providing medication, food, clothing and serving as a vital source of natural remedies. The increasing demand for natural remedies as opposed to synthetic ones has prompted the exploration of several alternative natural p...

Introduction: Foodborne trichothecene T-2 Toxin, is a highly toxic metabolite produced by Fusarium species contaminating animal and human food, causing multiple organ failure and health hazards. T-2 toxins induce hepatotoxicity via oxidative stress causing hepatocytes cytotoxicity and genotoxicity. In this study, curcumin and taurine were investiga...

Throughout history, humans have heavily relied on plants for both nourishment and the treatment of diseases. Breast cancer chemotherapies are expensive, have side effects, and may develop resistant cells. This shows the need for natural therapies to reduce the side effects of pharmacological remedies. Our objective was to isolate phytochemicals fro...

A variety of active chemicals found in medicinal plants can be used to develop new medications with few adverse effects. In vitro and in silico analyses were used to evaluate the anticancer properties of Juniperus procera fruit and leaf extracts. Here, we show that the methanolic extract from J procera fruit and leaf extracts inhibits 2 human ovari...

Background Breast cancer poses a major threat to female health worldwide. One of the medicinal plants used in traditional Saudi medicine is the Juniperus procera (Arar) plant, which is used to cure various illnesses, including cancer. Objectives The cytotoxic properties of Saudi J. procera extracts and their regulatory mechanisms against tumorigen...

The key step in the biosynthesis of estrogen is the enzyme activity of aromatase. Several malignancies, including breast cancer, have been linked to the initiation and progression of estrogen overexpression. Exemestane, Arimidex and Femara are the most common aromatase inhibitors used to treat hormone-dependent breast cancers. Drug resistance and s...

Medicinal plants continue to be a crucial source of safe, less toxic, economical, available, and reliable natural medicine supplies all over the world. Balanites aegyptiaca Del. (Zygophyllaceae), commonly known as the "desert date", is a thorny shrub or tree found in arid parts of Africa and South Asia. It has traditionally been used to cure a vari...

Introduction: Foodborne trichothecene T-2 Toxin, is a highly toxic metabolite produced by Fusarium species contaminating animal and human food, causing multiple organ failure and health hazards. T-2 toxins induce hepatotoxicity via oxidative stress causing hepatocytes cytotoxicity and genotoxicity. In this study, curcumin and taurine were investiga...

The process of investigating a possible cure for coronavirus disease 2019 (COVID-19) in vitro and in vivo may take a long time. For this reason, several in silico studies were performed in order to produce preliminary results that could lead to treatment. Extract of Juniperus procera Hochst is used as a traditional medicine for recovery from flu in...

Several anticancer drugs have been developed from natural products such as plants. Successful experiments in inhibiting the growth of human cancer cell lines using Saudi plants were published over the last three decades. Up to date, there is no Saudi anticancer plants database as a comprehensive source for the interesting data generated from these...

An experiment was conducted to explore the effect of water deficit on 2S albumin gene expression in Moringa oleifera with a predication of its allergenic reactivity. Drought was applied to 20-day-old plants for 1 month by limiting the irrigation water to half the control level. Soil water content and plant relative water content of drought treatmen...

A method was established, based on artificial fruit dehiscence, to collect seeds and silk fibers of C. procera without any loss. The seeds and floss obtained by this method were compared with those collected naturally. Natural fruit dehiscence caused a marked decrease in seeds and fibers yielded from C. procera. The seeds and fibers obtained under...

The most common inherited disease in European populations is cystic fibrosis. Mutations in the gene lead to loss of function of the cystic fibrosis transmembrane conductance regulator protein (CFTR). CFTR is a member of the ATP-binding cassette family of membrane proteins that mostly act as active transporters using ATP to move substances across me...

Cystic fibrosis is an autosomal recessive disease caused by mutations in the cystic fibrosis trans-membrane regulator (CFTR) gene. It is not a rare disease, but occurs in one in every 2500 live births in the Caucasian population. To date, more than 1950 mutations have been identified in the gene. The CFTR gene translates into CFTR protein which fun...

Significance Intrinsically disordered proteins lack persistent folded structure but are abundant and critical for regulatory protein interactions. They represent a challenge to the structure/function paradigm, particularly when significant disorder remains on interaction with partners. Although many disordered protein interactions have been describ...

By mass spectrometry analysis of mouse Cystic Fibrosis Transmembrane-conductance Regulator (mCFTR) expressed in yeast we have detected 21 phosphopeptides accounting for 22 potential phospho-residues, 12 of which could be unambiguously assigned. Most are conserved in human CFTR (hCFTR) and the majority cluster in the Regulatory Domain, lying within...

2 Abstract The cystic fibrosis transmembrane conductance regulator (CFTR) is a transmembrane protein that functions as an ion channel. Mutations in this protein cause Cystic Fibrosis. For this reason, it is important to study the structure and function of CFTR. In this study, constructs of CFTR (C-terminii), a CFTR-interacting protein and full-leng...

Typescript. Thesis (Ph. D.)--Florida State University, 2000. Includes bibliographical references (leaves 160-163). Photocopy.

Typescript. Thesis (M.A.)--Washington State University, 1983. Includes bibliographical references (leaves 199-202).