Asuman Dogac

Middle East Technical University | METU

The PHR systems need to be integrated with a wide variety of healthcare IT systems including EHRs, electronic medical devices, and clinical decision support services to get their full benefit. It is not possible to sustain the integration of PHRs with other healthcare IT systems in a proprietary way; this integration has to be achieved by exploitin...

Pre-approval clinical trials cannot guarantee that drugs will not have serious side effects after they are marketed. Post-approval drug safety data studies aim to address this problem, however, their effectiveness is started to be discussed especially after recent examples of drug withdrawals. This is due to the fact that, current post market safet...

Patient Empowerment engages individuals in taking care of their own health. This has been identified as a key element of change for improved quality and safety in healthcare. In the iCARDEA project, we aim at enabling cardiovascular implantable electronic device (CIED) patients to take a more active role in their own healthcare management by offeri...

For patients with Cardiovascular Implantable Electronic Devices (CIEDs), telemonitoring promises improved quality of life and safety, since events recorded by the device or observed by the patient can alert a health professional. Taking into account the latest clinical guidelines when responding to such alerts, is a topic of active research address...

The SAPHIRE project aimed to develop an intelligent healthcare monitoring and decision support system on a platform integrating the wireless medical sensor data with hospital information systems. In this paper one of the two demonstrator environments—the homecare scenario—is described from the medical and technical point of view. A retrospective vi...

Cardiovascular Implantable Electronic Devices (CIED) are gaining popularity in treating patients with heart disease. Remote monitoring through care management systems enables continuous surveillance of such patients by checking device functions and clinical events. These care management systems include decision support capabilities based on clinica...

One of the goals of iSURF project is creating an interoperability platform in order to enable the exchange of planning data between enterprises and especially across domains. The interoperability platform of iSURF is named iSURF Interoperability Service Utility (iSURF ISU). Interoperability should be regarded as a service that users can utilize any...

One of the key challenges in supply chain collaboration is to improve the efficiency and effectiveness of the suplly chain planning process to handle rapidly changing customer demands. Trading partners usually have different competencies based on their business strategies and investments. They have varying sources of information and also dissimilar...

In cardiology departments supporting implantation and follow-up of Cardiovascular Implantable Electronic Devices (CIED), relevant clinical data reside in autonomous healthcare information systems that support different health information technology (HIT) standards and proprietary data formats. Each organization chooses the Electronic Health Record...

The users of a content repository express the semantics they have in mind while defining the content items and their properties, and forming them into a particular hierarchy. However, this valuable semantics is not formally expressed, and hence cannot be used to discover meaningful relationships among the content items in an automated way. Although...

Providing an interoperability infrastructure for Electronic Healthcare Records (EHRs) is on the agenda of many national and regional eHealth initiatives. Two important integration profiles have been specified for this purpose, namely, the "Integrating the Healthcare Enterprise (IHE) Cross-enterprise Document Sharing (XDS)" and the "IHE Cross Commun...

No document standard is sufficient for all purposes because the requirements significantly differ among businesses, industries, and geopolitical regions. On the other hand, the ultimate aim of business document interoperability is to exchange business data among partners without any prior agreements related to the document syntax and semantics. The...

Effective use of electronic healthcare records (EHRs) has the potential to positively influence both the quality and the cost of health care. Consequently, sharing patient's EHRs is becoming a global priority in the healthcare information technology domain. This paper addresses the interoperability of EHR structure and content. It describes how two...

Health Level Seven (HL7) is a prominent messaging standard in the eHealth domain, and with HL7 v2, it addresses only the messaging layer. However, HL7 implementations also deal with the other layers of interoperability, namely the business process layer and the communication layer. This need is addressed in HL7 v3 by providing a number of normative...

Clinical guidelines are developed to assist healthcare practitioners to make decisions on patient's medical problems, and as such they communicate with external applications to retrieve patient data to initiate medical actions through clinical workflows, and transmit information to alert/reminder systems. The interoperability problems in the health...

One of the key challenges in supply chain collaboration is to improve the efficiency and effectiveness of the suplly chain planning process to handle rapidly changing customer demands. Trading partners usually have different competencies based on their business strategies and investments. They have varying sources of information and also dissimilar...

Currently in the travel domain most of the travel products are sold through Global Distribution Systems (GDSs). Since only major airline companies or hotel chains can afford to join GDSs, it is difficult for small and medium enterprises to market their travel products. In this paper, we describe a middleware, called SATINE, to address this problem....

Integrating healthcare enterprise (IHE) specifies integration profiles describing selected real world use cases to facilitate the interoperability of healthcare information resources. While realizing a complex real-world scenario, IHE profiles are combined by grouping the related IHE actors. Grouping IHE actors implies that the associated business...

Due to increasing percentage of graying population and patients with chronic diseases, the world is facing serious problems for serving high quality healthcare services to citizens at a reasonable costs. In this paper, we are providing a Clininical Desicion Support system for remote monitoring of patients at their homes, and at the hospital to decr...

Turkey's National Health Information System (NHIS) aims to provide a nation-wide infrastructure for sharing the Electronic Health Records (EHRs). The current implementation supports the transfer of EHRs, called the "Transmission Schema" instances from the Family Medicine Information Systems (FMIS) and the Hospital Information Systems (HIS) to the N...

One of the key problems in healthcare informatics is the inability to share patient records across enterprises. To address this problem, an important industry initiative called "integrating the healthcare enterprise (IHE)" specified the "cross enterprise document sharing (XDS)" profile. In the IHE XDS, healthcare enterprises that agree to work toge...

A number of Electronic Health Record (EHR) standards an d frameworks have been developed to assist with the interoperability and integration of distributed EHR information. Ideally, all EHR system sw ould adopt commo n and systematized hierarchies of component names, us em ulti-lingual clinical coding system sw ith perfect cross-mappings and use id...

One of the key problems in healthcare informatics is the lack of interoperability among different healthcare information systems. Interoperability can be investigated in different categories in the eHealth domain, such as the interoperability of the messages exchanged between healthcare applications, interoperability of Electronic Healthcare Record...

Web service technology changes the way of conducting business by opening their services to the whole business world over the networks. This property of Web services makes the security and privacy issues more important since the access to the services becomes easier. Many Web service standards are emerging to make Web services secure and privacy pro...

In this chapter, we describe an infrastructure enabling archetype-based semantic interoperability of Web service messages exchanged in the health care domain. We annotate the Web service messages with the OWL representation of the archetypes. Then, by providing the ontology mapping between the archetypes, we show that the interoperability of the We...

Most medical information systems store clinical informa-tion about patients in proprietary format. To address the resulting interoperability problems, several electronic health record (EHR) standards that enable structured clini-cal content for the purpose of exchange are currently under development. In this article, we present a brief overview of...

An essential element in defining the semantics of Web services is the domain knowledge. Medical informatics is one of the few domains to have considerable domain knowledge exposed through standards. These standards offer significant value in terms of expressing the semantics of Web services in the healthcare domain.In this paper, we describe the ar...

The object-oriented database management systems store references to objects (implicit joins, precomputed joins), and use path expressions in query languages. One way of executing path expressions is pointer chasing of precomputed joins. However it has been previously shown that converting implicit joins to explicit joins during the optimization pha...

Healthcare professionals need access to accurate and complete healthcare records for effective assessment, diagnosis and treatment of patients. The non-interoperability of healthcare information systems means that interenterprise access to a patient's history over many distributed encounters is difficult to achieve. The ARTEMIS project has develope...

Using archetypes is a promising approach in providing se- mantic interoperability among healthcare systems. To real- ize archetype based interoperability, the healthcare systems need to discover the existing archetypes based on their se- mantics; annotate their archetypes with ontologies; compose templates from archetypes and retrieve corresponding...

Currently, clinical information is stored in all kinds of proprietary formats through a multitude of medical information systems available on the market. This results in a severe interoperability problem in sharing electronic healthcare records. To address this problem, an industry initiative, called "Integrating Healthcare Enterprise (IHE)" has sp...

The SAPHIRE project aims to develop an intelligent healthcare monitoring and decision support system on a platform integrating the wireless medical sensor data with hospital information systems. In the SAPHIRE project, patient monitoring will be achieved by using agent technology where the "agent behaviour" will be supported by intelligent clinical...

In this chapter, we describe an infrastructure enabling archetype-based semantic interoperability of Web service messages exchanged in the health care domain. We annotate the Web service messages with the OWL representation of the archetypes. Then, by providing the ontology mapping between the archetypes, we show that the interoperability of the We...

Medical information systems today store clinical information about patients in all kinds of proprietary formats. To address the resulting interoperability problems, several Electronic Healthcare Record standards that structure the clinical content for the purpose of exchange are currently under development. In this article, we present a survey of t...

In this article, we describe an infrastructure enabling archetype-based semantic interoperability of Web Service messages exchanged in the health care domain. We annotate the Web Service messages with the OWL representation of the archetypes. Then, by providing the ontology mapping between the archetypes, we show that the interoperability of the We...

One of the most challenging problems in the healthcare domain is providing interoperability among healthcare information systems. In order to address this problem, we propose the semantic mediation of exchanged messages. Given that most of the messages exchanged in the healthcare domain are in EDI (Electronic Data Interchange) or XML format, we des...

ebXML is a standard from OASIS and UN/CEFACT which specifies an infrastructure to facilitate electronic business. In this paper, we address how ebXML registry semantics support can be further enhanced to make it OWL aware. OWL constructs are represented through ebXML registry information model constructs, and stored procedures are defined in the eb...

This text provides an overview of e-commerce and a comparative treatment of the main concepts, standards and technologies in this complex area. It then moves through topics such as building an electronic marketplace, personalization, mobile e-commerce and security issues http://www.amazon.co.uk/E-Commerce-Technology-Asuman-Dogac/dp/032111616X http:...

One of the most challenging problems in the healthcare domain is providing interoperability among healthcare information systems. In order to address this problem, we propose the semantic mediation of exchanged messages. Given that most of the messages exchanged in the healthcare domain are in EDI (Electronic Data Interchange) or XML format, we des...

Today, the travel information services are dominantly provided by Global Distribution Systems (GDS). The Global Distribution Systems provide access to real time availability and price information for flights, hotels and car rental companies. However GDSs have legacy architectures with private networks, specialized hardware, limited speed and search...

Agents show considerable promise as a new paradigm for software development. However for wider adoption and deployment of agent technology, powerful design and development tools are needed. Such tools should empower software developers to cater agent solutions more efficiently and at a lower cost for their customers with rapidly changing requiremen...

Agent Academy (AA) aims to develop a multi-agent society that can train new agents for specific or general tasks, while constantly retraining existing agents in a recursive mode. The system is based on collecting information both from the environment and the behaviors of the acting agents and their related successes/failures to generate a body of d...

Web services, like their real life counterparts have several properties and thus truly useful semantic information can only be defined through standard ontology languages. Semantic Web is an important initiative in this respect. However, although service registries are the major mechanisms to discover services, the semantic support provided by serv...

The inherent limitations of mobile devices necessitate information to be delivered to mobile clients to be highly personalized according to their profiles. This information may be coming from a variety of resources like Web servers, company intranets, email servers. A critical issue for such systems is scalability, that is, the performance of the s...

Today's Internet based businesses need a level of interoperability which will allow trading partners to seamlessly and dynamically come together and do business without ad hoc and pro- prietary integrations. Such a level of interoperability involves being able to fnd potential busi- ness partners, discovering their services and business processes,...

Web service technology is an Internet-based distributed computing paradigm to address interoperability in heterogeneous distributed systems. In this paper, we present a privacy framework for Web services which allows user agents to automatically negotiate with Web services on the amount of personal information to be disclosed on behalf of the user....

Web services have become a main thrust of the IT industry and there has been considerable development in this area. There are two almost universally accepted standards: SOAP (Simple Object Access Protocol) for invoking services and WSDL (Web Services Description Language) for describing the technical specifications of the services. There are well-e...

ISTAG has developed the concept of Ambient Intelligence (AmI) to provide a vision on how the Information Society will develop. The aim is to achieve better integration of technology into our environment, so that people can freely and interactively use it. An indispensable component of AmI is user context. We claim that to realize the vision of AmI...

In this paper we describe a framework for exploiting the semantics of Web services through UDDI registries. As a part of this framework, we extend the DAML-S upper ontology to describe the functionality we find essential for e-businesses. This functionality includes relating the services with electronic catalogs, describing the complementary servic...

this paper we describe a framework for exploiting the semantics of Web services through UDDI registries. As a part of this framework, we extend the DAML-S upper ontology to describe the functionality we find essential for ebusinesses. This functionality includes relating the services with electronic catalogs, describing the complementary services a...

Comprehensive semantic descriptions of Web services are essential to exploit them in their full potential, that is, discovering them dynamically, and enabling automated service negotiation, composition and monitoring. The semantic mechanisms currently available in service registries which are based on tax- onomies fail to provide the means to achie...

In this article we address delivering highly personalized context sensitive (i.e., time and location dependent) information to mobile clients. We believe providing highly personalized information to mobile clients from a variety of resources like e-mail servers, Web servers, and content providers will be an important service. Mobile network operato...

This paper describes an implementation of open market-place platform based on CommerceNet's eCo framework. eCo is a specification for application interoperability and to make it useful for market participants not only an implementation but also several market specific services are necessary. ... http://www.cheshirehenbury.com/ebew/e2001abstracts/se...

Business-to-business (B2B) e-commerce is booming thanks to the ubiquity of the Internet, which dwarfs the coverage of EDI VANs. B2B e-commerce needs to seamlessly and dynamically handle the interactions among a vast variety of organizations without ad hoc and proprietary integrations. A number of B2B e-commerce frameworks have emerged as a result....

The inherent limitations of mobile devices necessitate information to be delivered to mobile clients to be highly personalized according to their profiles. This information may be coming from a variety of resources like Web servers, company intranets, email servers. A critical issue for such systems is scalability, that is, the performance of the s...

Electronic commerce is happening at a very fast pace and business-to-business ecommerce is taking the lead, a very important part of which is the supply chain integration and automation. There is a high demand for well accepted interoperability standards which need to be fitted together for supply chain integration to meet the business demands such...

this article we will demonstrate the technology through an example scenario where a user accesses the METU Virtual Bookstore to buy a book about history of military weapons. The user selects "history" in his first click, "military" in his second click and "weapons" on his third click. The user then clicks "primitive", views it for 15 seconds, backs...

The progress and wider dissemination of electronic commerce will be facilitated through interoperability infrastructures. Commerce Net's eCo framework is a promising effort in this direction. In the eCo framework, businesses participate in a marketplace through standard interfaces for their services and by exchanging standardized documents. This fr...

bject-orientation, with its encapsulation and abstraction capabilities, enable the development of wrappers which encapsulate a particular repository and provide a common DBMS-like interface to the rest of the system. Fundamentally, interoperability of systems does not imply distribution. However, in practice, the systems that interoperate are usual...

In this paper we describe a mechanism for invoking external applications from XML documents and returning the results back into the documents such that it becomes possible to create dynamic XML documents with content fetched from external resources such as remote databases or legacy applications. One possible application is to support dynamic elect...

We propose an electronic marketplace architecture, called MOPPET, where the commerce processes in the marketplace are modeled as adaptable agent-based workflows. The higher level of abstraction provided by the workflow technology makes the customization of electronic commerce processes for different users possible. Agent-based implementation, on th...

In this paper we describe a mechanism for invoking external applications from XML documents and returning the results back into the documents such that it becomes possible to create dynamic XML documents with content fetched from external resources such as remote databases or legacy applications. One possible application is to support dynamic elect...

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In this paper we describe an architecture that provides for automating and monitoring the flow of control and document over the Internet among different organizations, thereby creating a platform necessary to describe higher order processes involving several organizations and companies. The higher order process is designed through a graphical user...

. Adapting to changes in its environment dynamically is a very important aspect of workflow systems. In this paper, we propose a component-based workflow system architecture specifically designed for this purpose. To allow for easy modification of workflow instances, an instance is designed as an object that contains all the necessary data and cont...

In this paper, main components of a workflow system that are relevant to the correctness in the presence of concurrency are formalized based on set theory and graph theory. The formalization which constitutes the theoretical basis of the correctness criterion provided can be summarized as follows: ffl Activities of a workflow are represented throug...

An electronic commerce (EC) process is a business process and defining it as a workflow provides all the advantages that come with this technology. Yet electronic commerce processes place certain demands on the workflow technology like the distribution of the load of the workflow engine to multiple servers, dynamic modification of workflows for ada...

In this paper, we describe a scenario for a distributed marketplace whose scope can be the whole Web where resource discovery agents find out about resources that may want to join the marketplace and electronic commerce is realised through buying agents representing the customers and the selling agents representing the resources like electronic cat...

In this paper, we describe an architecture for an open marketplace exploiting the workflow technology and the currently emerging data exchange and metadata representation standards on the Web. In this market architecture electronic commerce is realized through the adaptable workflow templates provided by the marketplace to its users. Having workflo...

METU Object-Oriented DBMS1 includes the implementation of a database kernel, an object-oriented SQL-like language and a graphical user interface. Kernel functions are divided between a SQL Interpreter and a C++ compiler. Thus the interpretation of functions are avoided increasing the efficiency of the system. The compiled by C++ functions are used...

Workflow processes are long-duration activities and therefore it is not possible to apply the well accepted correctness techniques of transactions directly to workflow systems. In this paper, we first mention the correctness problems of workflow systems and then exploit the available semantics in workflow specification in the form of data and seria...

. This paper describes the design and implementation of a kernel for an OODBMS, namely the METU Object-Oriented DBMS (MOOD). MOOD is developed on the Exodus Storage Manager (ESM). MOOD kernel provides the optimization and interpretation of SQL statements, dynamic linking of functions, and catalog management. SQL statements are interpreted whereas f...

CORBA offers a useful methodology and middleware for building interoperable databases.

Workflow management systems aim to automate the execution of business processes. One of the objectives of the workflow systems is to include the already existing applications such as legacy applications as well as new applications, which are termed as tasks, into the system and provide synchronized execution among them. To achieve this, a mechanism...