Asma Abdelaziz salim Radwan

Asma Abdelaziz salim Radwan
An-Najah National University · Department of Pharmacy

About

13
Publications
3,284
Reads
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179
Citations
Additional affiliations
September 2009 - August 2013
Johannes Gutenberg-Universität Mainz
Position
  • Researcher
September 2009 - August 2013
Johannes Gutenberg-Universität Mainz
Position
  • Researcher

Publications

Publications (13)
Article
Full-text available
Background Postmenopausal women compliance to alendronate therapy is suboptimal due to the complex dosing requirements. The poor compliance may increase their potential of fractures and the prevalence of side effects. In this study, the compliance of osteoporotic women on bisphosphonate therapy to the complex dosing instructions and their knowledge...
Article
Full-text available
Background: The investigation of volatile oils used in traditional medicine is vital to enhance the quality of healthcare. This study is aimed at screening the antioxidant and antimicrobial properties of Micromeria fruticosa serpyllifolia volatile oils from three different regions in Palestine (north, middle, and south). Methods: Volatile oils o...
Article
Background Food may affect the oral absorption of drugs. Purpose: The aim of the present study was to investigate the influence of food on the oral absorption of Clarithromycin by evaluating the effect of media parameters such as; pH, bile secretions and food composition on the release of the drug from immediate release tablet, using in vitro and i...
Article
Dissolution testing has emerged as an essential quality-control tool to monitor batch-to-batch consistency during drug development. The aim of this study was to assess the dissolution performance of drug products containing ibuprofen as active pharmaceutical ingredient available on the Palestinian market. Ibuprofen is one of the most widely used an...
Article
Background Many generic pharmaceutical products are currently available on the market place worldwide. Recently, there is a growing concern on the quality and efficacy of generic products. However, health care professionals such as physicians and pharmacists are in difficult situations to choose among alternatives. Purpose The aim of this study is...
Article
Background Food–drug interactions can produce undesirable outcomes during the therapy process. The pharmacist is responsible for providing patients counseling about common food-drug interactions. Knowledge of such interactions is important to avoid their occurrence. Objective This study aimed to assess the knowledge and awareness of community pharm...
Article
Full-text available
In this study, the in vitro and in vivo interchangeability between generic candesartan 16 mg and the branded formulation was assessed. The in vitro release of these products was conducted in 3 pH media (1.2, 5.0, and 6.8), and similarity factors (f2) were calculated. This bioequivalence study was a randomized, 2‐period crossover study that included...
Article
Background: The clinical implications of food-drug interactions may have to be taken seriously into account with oral drugs administration in order to minimize variations in drug bioavailability. Food intake may alter physiological changes in the pH and viscosity of the gastrointestinal lumen, which could affect the oral absorption of drugs. Purp...
Article
Full-text available
This study was undertaken to evaluate the effect of Corchorus Olitorius (Molokhia) soup on the oral absorption of ciprofloxacin from solid dosage forms in rabbits. A single dose of ciprofloxacin tablet (125 mg) was administered to rabbits in a fasted state or with Molokhia soup. Plasma ciprofloxacin concentrations were measured by high-performance...
Article
Food intake may delay tablet disintegration. Current in vitro methods have little predictive potential to account for such effects. The effect of a variety of factors on the disintegration of immediate release tablets in the gastrointestinal tract has been identified. They include viscosity of the media, precipitation of food constituents on the su...
Article
Much interest has been expressed in this work on the role of water diffusivity in the release media as a new parameter for predicting drug release. NMR was used to measure water diffusivity in different media varying in their osmolality and viscosity. Water self-diffusion coefficients in sucrose, sodium chloride and polymeric HPMC solutions were co...
Article
A negative food effect, i.e. a decrease in bioavailability upon the co-administration of compounds together with food, has been attributed particularly with high solubility/low permeability compounds (BCS class III). Different mechanisms have been proposed including intestinal dilution leading to a lower concentration gradient across the intestinal...

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