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Publications
Publications (63)
This study aimed to explore whether maternal food and nutrition literacy (FNL) can mitigate negative effects of food insecurity on children’s eating habits and assist food-insecure households in making better nutrition choices with limited resources available. A cross-sectional study was conducted on children aged 6 to 12 years and their mothers. F...
Background: More than half of diabetic patients finally develop hypertension which remarkably increases the risk of multiple complications. This study aims to assess the association between dietary indices, antioxidant intake and bioactive foods, and hypertension in diabetic patients. Methods: This was a cross-sectional population-based study on ba...
Background and objective
Physical activity has benefits for the cardiovascular system, however, what levels and types of activity provide optimal cardiovascular health is unclear. We aimed to determine the level of physical activity that has the most benefits against cardiovascular diseases (CVD).
Methods
PubMed, Scopus, and Web of Science were se...
We aimed to prospectively assess the association between variety and quantity of fruits and vegetables (FV) and cardiovascular diseases (CVD) incidence and mortality due to the limited evidence. Our analysis included 2,918 adults with a follow-up period of 29,559 person-years. An inverse association was detected between fruit intake and the risk of...
In this manuscript, we conducted a comprehensive review of the diverse effects of peppermint on human health and explored the potential underlying mechanisms. Peppermint contains three main groups of phytochemical constituents, including essential oils (mainly menthol), flavonoids (such as hesperidin, eriodictyol, naringenin, quercetin, myricetin,...
Background
Although studies have reported an inverse association between fruits, vegetables, and fiber consumption and all-cause and cause-specific mortality, the issue remains incompletely defined in the Middle Eastern population.
Aims
The current study aimed to investigate the association between dietary fiber, fruit, and vegetable intake and al...
Objective
We designed a new type of ‘physical activity calorie equivalent’ (PACE) food label in Iran to compare its effect with that of the traffic light food label (TLL) on caloric choices.
Design
Mixed-method study.
Participants
Mothers of school children between the ages of 6–12 years.
Setting
In the qualitative phase, 10 focus group discussi...
Background
Oxymel is a functional beverage with a rich historical background of use in multiple societies. Various simple and compound oxymels are prescribed in certain complementary and traditional medical systems, including traditional Persian Medicine. In recent years, numerous clinical and preclinical studies have been conducted in the pharmacy...
Objectives:
The aim of our study was to compare four lifestyles-healthy diet and low activity, unhealthy diet and high activity, unhealthy diet and low activity, and healthy diet and high activity-in relation to the risk of cardiovascular disease (CVD) and all-cause mortality.
Methods:
A total of 6504 adults ages ≥35 y were recruited to particip...
In 2019, a new coronavirus causing a flu-like syndrome was discovered in Chinese province of Hubei and there was a subsequent outbreak in Wuhan in December 2019. The severity and mortality of COVID-19 are affected by several preexisting comorbidities such as type 2 diabetes mellitus (T2DM). A more severe complication of COVID-19 in patients with di...
We aimed to evaluate the effect of spirulina sauce on glycemic indices, lipid profile, oxidative stress markers, and anthropometric measurement in type 2 diabetic patients. Forty patients were randomly assigned to receive 20 g/day spirulina sauce (containing 2 g of spirulina) or placebo for 2 months. Anthropometric and biochemical indices were meas...
Introduction:
In this study, we sought to summarize the associations between overall, plant-, and animal-based low carbohydrate diet (LCD) scores and the risk of all-cause, cardiovascular disease (CVD), and cancer mortality from prospective cohort studies.
Methods:
We searched PubMed, Scopus, and Web of Science up to January 2022. We included pr...
Background: Excessive inflammatory response is associated with several diseases. Recently, there has been an increasing trend for investigation of the acute or short-term effects of whey protein alone or in combination with carbohydrates on inflammatory status, especially in athletes. This systematic review aimed to clarify these effects. Materials...
This randomised controlled trial aimed to investigate the effect of date kernel on glycaemic control, lipid profile, and weight in women with overweight and obesity. A total of 124 women with overweight or obesity were randomly assigned to receive the date kernel supplement or placebo for 12 weeks. Haemoglobin A1c (HbA1c) was measured by high‐perfo...
Abstract The phenolic content of olive oil has a role in cardiovascular protection. Some clinical trial studies demonstrated that phenolic compounds of olive oil have antioxidant activity which can protect macronutrients from oxidative damages. The aim of this study was to summarize the results of clinical trials which assessed the effects of high‐...
Recent studies have demonstrated the effect of probiotics, prebiotics, and synbiotics on adiponectin and leptin levels; however, those findings remain contested. The present study aimed to explore the impact of probiotics/synbiotics on appetite-regulating hormones and the desire to eat.
Methods
A systematic review was conducted by searching the Me...
Background
In this study, we assessed the risk of cardiovascular diseases (CVDs) and all-cause mortality in subjects having an only physical activity or a healthy diet or both compared to those having none of these healthy behaviors in the Golestan Cohort Study (GCS).
Methods
A total of 50,045 participants aged ≥ 40 years were recruited from Goles...
Acorn is a nutritious fruit with the reported potential of ameliorating diseases, including diabetes. This research aimed to assess the effects of acorn muffin consumption on glycemic, lipid indices, and appetite in patients with type 2 diabetes. Sixty‐six subjects were dichotomized to receive either one muffin containing 10 grams of acorn flour or...
Objective: The aim of this randomized controlled trial (RCT) was to investigate the effect of date kernel on glycemic control, lipid profile, and weight in women with overweight and obesity.
Design: One hundred twenty-four women with overweight or obesity were randomly assigned to receive the date kernel supplement or placebo for 12 weeks. Serum Hb...
This systematic review and meta-analysis study was conducted to summarize the effects of garlic or its major components on hepatic triglyceride and cholesterol content, serum alanine transaminase (ALT) and aspartate transaminase (AST) levels, and liver weight. We searched PubMed, Embase, Scopus, and Web of Knowledge databases. Data were pooled, and...
Although the available evidence emphasizes the beneficial effects of probiotics in normalizing various cardiometabolic markers, there is still substantial uncertainty in this regard. Thus, we set out to determine the effect sizes of probiotics on blood lipid parameters more coherently. A systematic literature search of the Medline (PubMed) and Scop...
Aims
Direct and indirect evidence were combined in this systematic-review and network meta-analysis (NMA) to assess and compare the effect of nutritional supplements on glycemic control, and rank the supplements accordingly.
Methods
PubMed, Scopus, and Web of Science were searched up to April 2021. We included randomized controlled trials that inv...
Background
The effect of bone marrow-derived mononuclear cells (BM-MNCs) after acute myocardial infarction (AMI) on myocardial function indices such as left ventricular ejection fraction has been widely studied. However, the effect of this intervention on major adverse cardiovascular events (MACE) was not the principal purpose of most investigation...
Background
The effect of transplantation of bone-marrow mononuclear cells (BM-MNCs) and mesenchymal stem cells (MSCs) on ejection fraction (LVEF) has been studied in patients with acute myocardial infarction (AMI) in clinical trials. This raises the question that which type of cell may help improve LVEF better in AMI patients. No meta-analysis of c...
The aim of the present study was to assess Aflatoxin‐M1 (AFM1) contamination in cheese samples from the West Asia region. Furthermore, AFM1 contamination was investigated based on the texture type (hard, semi‐soft/semi‐hard and soft) and the maturation process (matured and fresh) of the cheese sampled. Our results indicated that AFM1 contamination...
Aim:
Colchicine as an anti-inflammatory drug might be effective in the treatment of atherosclerosis, an inflammatory-based condition. The aim of this systematic review and meta-analysis was to evaluate the impact of colchicine on acute coronary syndrome (ACS).
Methods:
We searched SCOPUS, PubMed, and Web of Science up to September 27, 2020. All...
Background
Colorectal cancer is the third leading cause of cancer deaths worldwide. Given the recent increasing trends in colorectal cancer incidence globally, up-to-date information on the colorectal cancer burden could guide screening, early detection, and treatment strategies, and help effectively allocate resources. We examined the temporal pat...
The effect of bone marrow-derived mononuclear cells (BM-MNCs) after acute myocardial infarction (AMI) on myocardial function indices such as ejection fraction (LVEF) has been widely studied. However, the effect of this intervention on major cardiovascular events (MACE) was not the principal purpose of most investigations and its role is unclear. Th...
Background
Trials investigating the role of mesenchymal stem cells (MSCs) in increasing ejection fraction (LVEF) after acute myocardial infarction (AMI) have raised some controversies. This study was conducted to find whether transplantation of MSCs after AMI can help improve myocardial performance indices or clinical outcomes.
Methods
Randomized...
We aimed to summarize the associations between food sources of fructose and cardiovascular diseases (CVD), cancer, and all-cause mortality risk using a systematic review and meta-analysis. We searched PubMed, Scopus, and Web of Science up to November 2020. We included cohort studies that investigated the relationship between mortality risk (all-cau...
Purpose
Colchicine as an anti-inflammatory drug might be effective in the treatment of atherosclerosis, an inflammatory-based condition. The aim of this systematic review and meta-analysis was to evaluate the impact of colchicine on acute coronary syndrome (ACS).
Methods
We searched SCOPUS, PubMed, and Web of Science up to September 27, 2020. All...
Background and aim:
Animal and human studies have indicated anti-diabetic effect of Asteraceae. The present study aimed to systematically review and analyze randomized controlled trials (RCTs) assessing the effect of Artemisia extract on glycemic status in patients impaired glycemic control.
Methods:
Web of Science, Cochrane library, EMBASE, and...
Introduction:
We sought to systematically review the association between meal glycemic index or glycemic load and sleep indicators.
Evidence acquisition:
PubMed, Scopus, Web of Science, and Embase were searched up to March 2021. Both observational and clinical trials studies, with both male and female participants of all ages, were included.
Ev...
Introduction
Hibiscus sabdariffa is a common ingredient in herbal tea blends. Several properties such as antihypertensive and antioxidant activities have been attributed to this plant. The aim of this systematic review and meta-analysis was to synthesize the knowledge about the effect of Hibiscus sabdariffa (sour tea) compared to other herbal teas...
ABSTRACT
This systematic review was conducted to summarize and clarify the evidence on the association between 25-hydroxyvitamin-D [25(OH)D] concentrations and coronavirus disease 2019 (COVID-19) risk and outcomes. PubMed, Scopus, and Web of Science databases and Google Scholar were searched up to 26 November 2020. All retrospective and prospective...
Despite the considerable importance of dairy consumption, aflatoxin‐M1 (AFM1) contamination can pose potential health threats for these products. In the present study, we systematically reviewed and conducted a meta‐analysis on the AFM1 contamination in yogurt samples of West Asia region. In the present study, electronic databases including PubMed,...
Background
Although several randomized controlled trials (RCTs) have supported the beneficial effects of higher meal frequency (MF) on cardiometabolic risk factors, the putative effects of higher MF on health remain inconclusive. This study systematically reviewed the evidence from RCTs of the effect of higher compared with lower MF on the blood l...
The human gut microbiota, a well-known factor influencing health and well-being, contains a massive amount of genetic material, which can be viewed collectively as an “alternate” genome that could be manipulated by external interventions. The impact of the gut microbiota on mood and depression has attracted significant attention from the research a...
The aim of this systematic review and meta-analysis was to evaluate the effect of probiotics, parabi-otics, synbiotics, fermented foods and other microbial forms on immunoglobulin production. We searched PubMed, Scopus, Web of Science, National Institute of Health Clinical Trials Register, and Cochrane Central Register of Clinical Trials, up to Feb...
Despite increasing evidence for the association of food-based dietary patterns with breast cancer risk, knowledge about the shape of the relationship and the quality of meta-evidence are insufficient. We aimed to summarize the associations between food groups and risks of breast cancer. We performed a systematic literature search of the PubMed and...
Bariatric surgery is a metabolic surgery known to be an efficient treatment for weight loss, with adequate long-term maintenance. Interestingly, some studies have reported a reduction in branched chained amino acids (BCAAs) after bariatric surgery, which putatively contributes to post-surgical metabolic improvement. The current systematic review an...
We performed a meta-analysis to provide quantitative estimates of fat mass (FM) and fat-free mass (FFM) changes in patients following bariatric surgery over 1 year. A systematic search of PubMed, SCOPUS and Web of Science databases was conducted; the pooled weighted mean difference (WMD) and 95% confidence intervals (CI) were calculated using a ran...
Background/Aims
Psychobiotics are probiotics or prebiotics that, upon ingestion in adequate amounts, yield positive influence on mental health via
microbiota-gut-brain axis regulation to modulate the circulating cytokines, chemokines, neurotransmitters, or neurotrophins levels.
We have recently shown that a psychobiotic combination (Lactobacillus h...
Objective
The present systematic review and meta-analysis was performed to evaluate the effect of cinnamon supplementation on blood lipid profiles in patients with type 2 diabetes.
Methods
A systematic search (with no language restrictions) was performed in PubMed, Embase, Scopus, Web of Science, and Cochrane Library to identify relevant clinical...
The therapeutic potential of green tea as a rich source of antioxidants and anti‐inflammatory compounds has been investigated by several studies. The present study aimed to systematically review and analyze randomized clinical trials (RCTs) assessing the effects of green tea, catechin, and other forms of green tea supplementation on levels of liver...
Effect of probiotics on various parameters of immune system including immune cells count levels has been demonstrated by clinical trials; however, as far as we know, no meta-analysis has been done. The aim of this systematic review and meta-analysis was to evaluate the effect of probiotic/synbiotic on immune cells in health and disease status.
We s...
Calorie restriction (CR) and reductions in protein intake in rodents result in increased lifespan and reduced levels of IGF-1. However, the changes in IGF-1 in humans in response to CR and elevated protein intake are confused. We conducted a systematic review and meta-analysis to investigate the effect of Calorie restriction (CR) or increase in pro...
Background:
Poor appetite and weight loss are common in melancholic depression. Probiotics and prebiotics have the capacity to affect host behaviour, appetite and weight change by modulating the gut microbiome. The aim of this post hoc analysis was to investigate the effect of supplementation with probiotic and prebiotic on appetite, in parallel w...
The current systematic review and meta-analysis investigated the effect of probiotic/synbiotic on a wide range of inflammatory and anti-inflammatory markers in healthy and various disease conditions. PubMed, SCOPUS and Web of Science databases were searched. All clinical trials which investigated the effect of oral administration of probiotic or sy...
The aim of this double blind, placebo-control trial, was to investigate the effect of prebiotic and probiotic on serum inflammatory cytokines (TNF-α, IL-1β, IL-6 and IL-10), Beck Depression Inventory (BDI) score and urinary cortisol in patients with major depressive disorder (MDD). Randomized participants (n = 110) received either the probiotic, pr...
Background
Disturbance in the equilibrium of the gut microbiota has been involved in the pathophysiology of depression. Probiotics have the potential to healthfully modulate the gut microbiome. Prebiotics could also be effective by stimulation of growth of some bacterial species in the gut microbiota.
Objective
The aim of this double blind clinica...
Progressive decline in CD4 cell counts is associated with human immunodeficiency virus (HIV) disease progression. Loss of CD4 cells might contribute to gut microbiota alteration and bacterial translocation. Probiotics, by inducing epithelial healing, may promote the restoration of the intestinal CD4+ T-cell population. The aim of this meta-analysis...
We assessed the impact of weight loss strategies including calorie restriction and exercise training on BMD in adults using a systematic review of randomized controlled trials. Weight reduction results in reduced BMD at the hip, but has less effect on the spine. Both calorie restriction and a combination of calorie restriction and exercise result i...
Malnutrition among HIV-infected people is a notable problem that can affect both the therapeutic response and severity of this illness. The aim of this study is to assess the nutritional status based on the body mass index of HIV-infected patients in Fars Province, Iran. This cross-sectional study enrolled 485 HIV-positive individuals. Anthropometr...
The current global burden of chronic diseases necessitates the introduction of new healthy food, including probiotic ones. Thus, the aim of the present study is to evaluate the suitability of different mixtures of soy and cow’s milk as probiotic food carriers. Soy milk prepared from soybeans was combined with cow’s milk at the concentrations level...
Objective: Micronutrient deficiencies are contributing factors to growth failure and loss of appetite. This study investigated the effect of multivitamin-mineral supplements on appetite and growth of preschool children with poor appetite and growth failure. Methods: The study was placebo-controlled, with 63 children (29 boys and 34 girls), 3 to 7 y...
The aim of the present study was to investigate the effect of addition of soymilk on physicochemical, microbial, and sensory characteristics of milk fermented with Lactobacillus acidophilus. Soybeans were blended 1:5 w/v with distilled water. The prepared soymilk was added to milk in combinations of 20%, 40%, and 60%. Milk was used as the control....
Background: The present clinical trial study aims at investigating the effect of daily energy intake in 6 isocaloric meals in comparison with the current meal pattern (3 meals and 2 small snacks per day) on type 2 diabetes risk markers in diabetes during 3-month period.
Methods: Eighty four type 2 diabetes patients were randomly divided into 6 iso...
Objective: Micronutrient deficiencies are contributing factors to growth failure and loss of appetite. This study investigated the effect of multivitamin-mineral supplements on appetite and growth of preschool children with poor appetite and growth failure. Methods: The study was placebo-controlled, with 63 children (29 boys and 34 girls), 3 to 7 y...
Introduction In order to grow sufficiently, children are at especial need for nutrients. If sufficient quantities of nutrients are not supplied by food or supplements, they may easily suffer from growth retardation. Poor appetite is one of the most common nutritional problems among preschool children. Children with poor appetite usually have low co...
Introduction: The prevalence of obesity is increasing worldwide. In Iran, the prevalence of obesity is 22% in
15-39 year-old individuals and 40% in those between 40 and 69 years old. These measures have been reported
as 16% and 26%, respectively in the rural population. One of the debatable issues which cause obesity is the meal
frequency. The p...
Questions
Questions (14)
Is there any way to convert median and its 95% CI to mean 95% CI?
In conducting meta-analysis of binary outcomes (in RCTs), in case the risk ratio has not been reported, what should we do with the studies that the number of outcomes occurrence is zero in both intervention and control groups? (for example, if we wanted to assess the effect of a drug on mortality, in some of the studies the number of deceased patients in both groups is zero), Is there any solution to not exclude these studies?
In conducting a meta-analysis, sometimes, some studies have reported geometric mean, while others have reported arithmetic mean. One solution for pooling these studies is calculating the ratio of the mean; I wanted to know if the ratio of the mean calculated as the following: mean intervention/mean control? and what should we do with standard deviation? Can we then pool the ratio of arithmetic mean and the ratio of geometric means?
I am conducting a meta-analysis. I came across a study that has reported mean and SD in the logarithmic scale. I wanted to transform it to pool with data from other studies. I calculate antilogarithm for the mean but I think I cannot calculate antilogarithm for SD ( it became a very small value). how I can calculate SD in a real scale in this situation?
What is Minimal Clinically Important Difference for total daily dose of insulin in diabetes?
In conducting meta-analysi, we come across to the article that have reported geometric mean. Is it possible to convert geometric mean to arithmetic mean ?
Is it possible to change estimated marginal mean to mean?
Is it correct to measure random urinary cortisol with the chemiluminescence system that is set for 24-hour urinary cortisol?
I need to determine serum tryptophan/ kynurenine ratio in my thesis. I will measure tryptophan level by HPLC but I couldn’t find anywhere to measure kynurenine by HPLC. Is this right if I measure serum tryptophan by HPLC and kynorenin by ELISA?
Which method is more accurate for measuring of urinary cortisol; LC-mass specterometry or immunoassay?
in what temperature urinary sample should be stored for measuring cortisol level -20 or -80 ?( Duration of the study is 6 month)
