Asiye Ugras Dikmen

Asiye Ugras Dikmen
Gazi University · Department of Public Health

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58
Publications
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425
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Publications

Publications (58)
Article
Background: Sedentary lifestyle is common in various age groups all over the world and it is an important public health issue because of its adverse effects on health. Taking actions against inactivity among medical students is important because they will become role models for their patients as future doctors. In this research, physical activity (...
Article
Background: Although dentists are among high-risk groups for COVID-19 due to their practice requiring to be in close proximity to patients’s oral cavities, there is a clear lack of studies on the frequency of hesitancy towards COVID-19 vaccines and the factors that influence the said hesitancy. This study aims to determine the factors causing hesit...
Article
Background: Irrational drug use not only causes a delay in the treatment of patients, failure to achieve full well-being, drug interactions and side effects, drug resistance but also creates economic negativities such as waste of resources and unnecessary workload. This study aims to investigate the irrational drug use behaviors of individuals ove...
Article
Objectives: Graft-versus-host disease is still one of the most important complications after hematopoietic stem cell transplantation. The risk factors remain unclear, with effects of graft-versus-host disease on survival varying among different centers. We aimed to determine risk factors that may affect development of graft-versus-host disease and...
Conference Paper
Full-text available
AbstractAims: This study aimed to investigate the clinical and chest computed tomography (CT) features associated with clinical parameters for coronavirus disease (COVID- 19) in the capital of Turkey, Ankara.Materials and methods: Epidemiological, clinical features, laboratory findings and radiological characteristics of 1563 hospitalised patients...
Article
Background and Objective The COVID-19 pandemic results in an intense flow of patients to hospitals especially to the intensive care units (ICUs) to be treated. The ICUs will therefore be confronted with a massive influx of patients (e.g. Spain and Italy). However, if the number of patients is higher than the resources available in ICUs, rationing d...
Article
Objective This study aimed to determine the level of anxiety in elderly individuals during the COVID-19 pandemic in Ankara province of Turkey and determine its associated factors. Methods a quantitative, qualitative mixed method study performed in June 1-10, 2020 during the compulsory homestay for elderly people in Turkey. The quantitative study w...
Article
Full-text available
Aims This study aimed to investigate the clinical and chest computed tomography (CT) features associated with clinical parameters for coronavirus disease (COVID-19) in the capital of Turkey, Ankara. Materials and Methods Epidemiological, clinical features, laboratory findings and radiological characteristics of 1,563 hospitalised patients with COV...
Article
Background: Previous studies have not shown the level of health literacy or associated factors on a national level in Turkey using a scale that has been adapted to the country and its culture. Objective: This study aimed to determine health literacy levels in Turkey and to investigate the association of health literacy with socioeconomic factors...
Article
Objective: The aim of this study is to show the consistence between the recommended guidelines regarding the triad of symptoms-cough, dyspnea, and fever-and the diagnosis of COVID-19. Methods:A prospective observational study conducted at a tertiary emergency department between April 2, 2020 and May 15, 2020 in Turkey. Detailed patient history, mai...
Article
Background Inadequate or misinformation about electroencephalography (EEG) and epilepsy may lead to anxiety in children and their parents. The purpose of this study was to make a simultaneous evaluation of the anxiety levels of children and parents before EEG procedures and to make a brief assessment of their knowledge about EEG. Methods and mater...
Article
Abnormal expression of enzymes involved in epigenetic mechanisms, such as DNA methyl transferases, can trigger large chaos in cellular gene expression networks and eventually lead to cancer progression. In our study, which is a pioneer in the literature that clinicopathologically evaluates the expression of 30 epi-miRNAs in prostate cancer (PCa), w...
Article
Full-text available
Background/aim: Pneumonia is the most serious clinical presentation of COVID-19. This study is aimed to determine the demographic, clinical, and laboratory findings that can properly predict COVID-19 pneumonia. Materials and methods: This study was conducted in Gazi University hospital. All hospitalized patients with confirmed and suspected SARS...
Article
Full-text available
Background-aim: In this study; it is aimed to evaluate the destructive behavioral disorders in children between the age of 6-18 years old who applied to various family health centers in Ankara. Method: The study was conducted as a cross-sectional study including 674 children and 337 parents who applied to family health centers in 4 different distri...
Article
Full-text available
Background: Although bronchial sleeve resections were performed instead of pneumonectomy in patients with insufficient pulmonary function initially, it is currently available as an alternative to pneumonectomy even in patients with adequate pulmonary reserve. Aims: In this study, we aimed to evaluate the sleeve resections performed for lung canc...
Article
Full-text available
Impact statement: Alternative agents that will increase the effectiveness of cisplatin, which are widely used in the advanced stage and metastatic bladder cancer, are being investigated. In previous studies, Cucurbitacin B (CuB), which is a natural compound from the Cucurbitaceae family has been shown to inhibit the proliferation of tumor cells an...
Article
Aim: Mammary serine protease inhibitor (maspin) acts as a tumor suppressor through the inhibition of cancer cell invasion and metastasis. Paradoxically, maspin levels are increased in some types of malignant cells. The aim of this study was to investigate the maspin expression in cervical dysplasia and cervical cancer, and to analyze its' relation...
Article
Full-text available
Objective: Suicide is the second leading cause of death in adolescence. Genetic studies implicate the genetic component of suicide independent from associated psychiatric disorder. Although genetics is an important factor that might be associated with suicide, limited progress is achieved to identify the candidate genes in adolescents. Methods: The...
Article
Objective: To assess the neuropsychological status of pediatric multiple sclerosis (MS) patients and its relationship with clinical variables in a longitudinal study. Methods: Patients with MS (n = 46) and age- and gender-matched healthy control subjects (HCs, n = 53) were given tests of non-verbal reasoning, attention/concentration, visuospatial j...
Article
Full-text available
Aim: Influenza is an important public health problem for the whole world and the prevalence of influenza vaccination is low.The aim was to determine the prevalence of influenza vaccination and adverse effect after seasonal influenza and/or pandemic A (H1N1) influenza vaccination in health care workers (HCW) working in Ankara.Methods: It is a cross-...
Article
In the present study, NF-κB inhibitor BAY 11-7082 and/or Hsp-27 inhibitor KRIBB-3 agents were used to investigate the molecular mechanisms mediating androgen receptor expression on prostate cancer cell lines. The decrease observed in androgen receptor and p65 expressions, particularly at 48 h, in parallel with the decrease in the phosphorylation of...
Article
Full-text available
Background and Design: Inflammation can lead to adverse outcomes in pregnancy. Some inflammatory diseases, such as rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, and psoriasis, are associated with preterm birth and low birth weight. The objectives of our study were to assess the effect of various inflammatory skin d...
Article
We aimed to describe rotavirus epidemiology and clinical findings including extraintestinal manifestations in a setting that has yet to introduce rotavirus vaccines in the national immunization program. A literature search was performed by using the key words “Turkey” and “rotavirus.” Ninety‐eight studies published between 1987 and 2016 including e...
Article
Full-text available
Introduction: In recent years, the necessity of childhood vaccination as well as adult vaccination has gained importance and practices continue to increase in many countries. Approaches to adult vaccination are needed to be known for the development of immunization services for the adult group and to improve the general health of the community in o...
Article
Full-text available
Background/aims: Endoscopy and colonoscopy are frequently performed procedures to evaluate the gastrointestinal system. These procedures are sometimes disturbing and painful for the patient. In gastrointestinal suits, endoscopy and colonoscopy may be performed on awake or sedated patients. Music therapy is a common and non-pharmacological treatmen...
Article
Prostate cancer is one of the most common types of cancer in men and the leading cause of death in developed countries. With the aid of molecular and genetic profiling of cancers, cancer molecular subtypes are paving the way for tailored cancer therapy. FOXA1 has been identified as one of the seven molecular subtypes of prostate cancer. FOXA1 is in...
Article
Full-text available
Objective: Decline of subnormal growth velocity(GV) and related factors during gonadotropin-releasing hormone analog(GnRHa) therapy for idiopathic central precocious puberty(ICPP) are unclear. We investigated the incidence of subnormal growth velocity, associated factors in patients with GnRHa therapy for ICPP. Methods: In this retrospective coh...
Article
Background: Immunological and inflammatory mechanisms play an important role in schizophrenia. In the literature, there are studies investigating neutrophil-lymphocyte ratio (NLR) association with schizophrenia. Aims: The purpose of this study was to compare NLR values between patients with schizophrenia and healthy controls. In addition, the study...
Article
Deregulated cancer cell metabolism plays an important role in cancer progression. Cancer cell metabolism has been in the centre of attention in therapeutical cancer cell targeting. Repurposed chemical agents, such as metformin and aspirin, have been studied extensively as preventive and therapeutic agents. Metformin is Food and Drug administration...
Article
Introduction: It is crucial to diagnose the subtype of lung cancer quickly and accurately for effective therapy. Conventional cytology staining sometimes provides limited information, and additional tissue is often required to diagnose lung cancer. Cell blocks (CB) recovered during endobronchial ultrasound-guided transbronchial needle aspiration (...
Article
Full-text available
Development of metastatic castration-resistant prostate cancer is a result of the lack of an apoptotic response by the tumor cells and loss of the ability to stick to adjacent cells through epithelial–mesenchymal transition. Although there are several strongly recommended biomarkers for determining prognosis of metastatic castration-resistant prost...
Article
Objective: In this study, we investigated the correlation between serum and urinary neopterin levels as well as the stage of the disease in women with endometrial cancer.Increased neopterin concentrations are reported in patients with activation of macrophages by interferon-γ, which includes the following: viral infections, autoimmune disorders, a...
Article
Background: Vitamin D receptor (VDR) gene polymorphisms have been studied in immune-mediated disorders, but not yet in immune thrombocytopenic purpura (ITP). We investigated whether VDR variants were associated with ITP in children. Methods: The study included 44 children with a diagnosis of ITP and 100 healthy controls. Five VDR polymorphisms (...
Article
Full-text available
Matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinase (TIMP) have a significant role in tissue remodeling related to cardiac function. In earlier studies, MMP-7 A-181G (rs11568818), C-153T (rs11568819), C-115T (rs17886546), and TIMP-2 G-418C (rs8179090) polymorphisms have been studied in various diseases. However, association be...
Article
Objective: This study aimed to determine, knowledge, attitude and satisfaction of people over the age of 18 admitted to some family health centers in Ankara about Community Health Centers. Methods: The participants of this study are 1218 people over the age of 18 admitted to some family health centers in Ankara. We conducted face to face interviews...
Article
Full-text available
Background/aim: Venous stasis during pneumoperitoneum in laparoscopic surgery is closely related to fibrin synthesis and deposition. The etiologic factors underlying fibrinolysis or hypercoagulability are not clearly defined. This study aimed to determine the effects of pneumoperitoneum time and pressure on coagulation cascade and the fibrinolytic...
Article
Certain prognostic factors for small cell lung cancer (SCLC) have been validated, but the prognostic role of 18F-FDG PET/CT still remains unclear. The aim of this study was to evaluate the prognostic significance of 18F-FDG PET/CT in patients with SCLC. We reviewed 142 patients with pathologically proven SCLC who underwent pre-treatment 18F-FDG PET...
Article
Purpose: To investigate the diagnostic value of endometrial thickness measurement on sonography in predicting endometrial pathologies in postmenopausal women with vaginal bleeding and in those with asymptomatic thickened endometrium. Methods: Six hundred two postmenopausal women with vaginal bleeding or asymptomatic thickened endometrium were ev...
Article
Objective: The aim of this study was to conduct a power analysis and assess the adequacy of the sample size of the original research articles published in the Turkey-centered SCIE (Science Citation Index Expanded) indexed orthopedics and traumatology journals. Material and Methods: 1036 articles published between January 2010 and May 2014 were eval...
Article
Intrahepatic cholestasis of pregnancy (ICP) is the most common pregnancy-specific liver disease, is characterized by pruritus, abnormal liver function and elevated serum bile acid levels. The main cause of ICP has not yet been identified. We aimed to provide a new perspective to the pathogenesis of by investigating the possible association of circu...
Article
In the present study we aimed to determine the effect of an AT-II antagonist candesartan on pancreatic microcirculation in an experimental model of acute necrotizing pancreatitis. There were five study groups with 10 animals in each. Pancreatitis was induced by intravenous infusion of cerulein and coadministration of glycodeoxycholate into biliopan...
Article
Full-text available
Background/aim: The aim of this study was to determine the frequency of and risk factors for physical violence, verbal violence, and mobbing experienced by nurses in a university hospital. Materials and methods: This was a cross-sectional study conducted at Gazi University Medical Faculty Hospital. A questionnaire form recommended by the WHO and...
Article
Full-text available
Our study aims to assess work accidents, which university hospital healthcare staff had pointed out. This study is a cross-sectional study. The universe is 1597 people working at Gazi University Faculty of Medicine. For data collection, a questionnaire has been used; for the assessment of occupational accidents that medical staff had stated. In the...
Article
Introduction:: The aim of this study was to investigate the incidence and risk factors for the development of nosocomial infections (NI) in elderly patients who were treated in the medical intensive care units (ICU). Factors affecting mortality were also evaluated. Materials and Method: A total of 433 patients who were treated in the ICU for over 4...

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