Ashima Sahni

• Astt prof at Kanya Maha Vidyalaya

Narcolepsy type 1 (NT1) has a probable autoimmune pathophysiology. Myasthenia gravis (MG) is an auto-antibody-mediated neuromuscular junction disorder. In the case report below we describe 2 women who were diagnosed with NT1 at ages 33 and 46 years, respectively. Both have seronegative MG and, although the MG was diagnosed earlier than the NT1, the...

Since the commencement of the COVID-19 pandemic, several variants of concern (VOCs) such as Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2) have been discovered and reported in various parts of the world. These viral mutants may have the potential to significantly affect the transmission of the virus, vaccine therapeutic efficac...

This article focuses on pattern and direction with which Dalit politics moves in Punjab. An attempt is made to understand political participation as well as voting behaviour of Dalits in Punjab, which is quite different when compared with political behaviour of Dalits in the rest of India. In this study, political participation and political gains...

Purpose of Review The cardiovascular morbidity associated with obstructive sleep apnea (OSA) changes with aging. This review addresses unique aspects of OSA-associated hypertension and cardiovascular disease (CVD) in the elderly. Recent Findings The risk of hypertension and CVD in OSA diminishes with aging. The standard apnea hypopnea index cut-of...

Study objectives: To explore the association of continuous positive airway pressure (CPAP) compliance with clinical outcomes in patients with type 2 diabetes (T2D) and obstructive sleep apnea (OSA) in a real-world setting. Methods: This was a retrospective study of patients with T2D diagnosed with OSA between 2010 and 2017. CPAP compliance (usag...

Objectives There exists a wide gap in the availability of mechanical ventilator devices and their acute need in the context of the COVID-19 pandemic. An initial triaging method that accurately identifies the need for mechanical ventilation in hospitalised patients with COVID-19 is needed. We aimed to investigate if a potentially deteriorating clini...

The recent trend for legalization of medicinal cannabis and cannabinoid-containing products, together with their soporific effects, has led to a surge of interest of their potential therapeutic role in the management of some common sleep disorders, such as insomnia, sleep disordered breathing, and restless legs syndrome, and less common disorders s...

Purpose of Review Obstructive sleep apnea (OSA) is associated with increased risk of morbidity and mortality. Positive airway pressure (PAP) therapy remains the gold standard treatment, but its use is often limited by patient compliance, hence the need to consider other potential therapies. Preliminary data may suggest potential role of cannabinoid...

Purpose: Early identification of a potentially deteriorating clinical course in hospitalized COVID-19 patients is critical since there exists a resource-demand gap for the ventilators. Materials: We aimed to develop and validate a deep learning-based approach to predict the need for mechanical ventilation as early as at the time of initial radiogra...

Continuous positive airway pressure (CPAP) treatment has been shown to be beneficial to patients with obstructive sleep apnea (OSA) by reducing blood pressure and possibly slowing progression of chronic kidney disease. However, there is a dearth of research on the effects of CPAP treatment, especially compliance, on these outcomes in patients with...

Excessive daytime sleepiness (EDS) can be caused by insufficient sleep but is also a manifestation of medical or sleep disorders and a side effect of medications. It impacts quality of life and creates safety concerns in the home, at work, and on the roads. Screening questionnaires can be used to estimate EDS, but further evaluation is necessary. E...

Traumatic brain injury (TBI) is a global health problem that affects millions of civilians, athletes, and military personnel yearly. Sleeping disorders are one of the underrecognized sequalae even though they affect 46% of individuals with TBI. After a mild TBI, 29% of patients have insomnia, 25% have sleep apnea, 28% have hypersomnia, and 4% have...