Arun Loganathan

Sheffield Teaching Hospitals NHS Foundation Trust | STH · Department of General Surgery

Laparoscopic repair of incisional hernias in obese patients with large and recurrent hernias can be challenging and are commonly performed using a mesh bridge technique, where the hernial sac is not excised and the fascial defect is not closed before inserting the mesh. This can result in higher rates of recurrence, seroma formation and bulging [2,...

Intra-abdominal sepsis is frequently seen and dealt with by surgeons. It presents as a spectrum of conditions ranging from uncomplicated localized infection through to severe systemic sepsis with generalized peritoneal infection. Complicated sepsis is frequently associated with a systemic inflammatory response, which can rapidly progress into septi...

Background. The precise etiology of fecal incontinence (FI), which occurs frequently following external beam radiotherapy (EBRT) for prostate carcinoma is unknown. It is possibly related to pelvic nerve injury. The aim of this study was to assess the incidence of pudendal nerve dysfunction in men with FI after EBRT for prostate cancer compared to m...

Background Transanal haemorrhoidal dearterialization (THD) is increasingly perceived as an effective and better tolerated alternative to excisional haemorrhoidectomy. The aim of this study was to evaluate outcomes and the patient experience of THD in an Australian population with grade III or IV haemorrhoids.MethodsA retrospective review of prospec...

Enteropathy-associated T cell lymphoma (EATCL) is an intestinal neoplasm of intra-epithelial T lymphocytes associated with coeliac disease. Although the incidence is rare, EATCL runs an aggressive disease course and produces multi-focal ulcerative lesions most commonly in the proximal small bowel. As such, patients may present with intestinal perfo...

To determine the contribution of the pudendal nerve to the anal continence mechanism by determining the correlation between pudendal nerve terminal motor latency (PNTML) and resting and squeeze anal canal pressures METHODS: 1051 patients were investigated with anorectal physiology studies between January 1998 and July 2010. Of these, 213 patients h...

Background Human colon may secrete substantial amounts of water secondary to chloride (Cl−) and/or potassium (K+) secretion in a variety of diarrhoeal diseases. Ion secretion occurs via Cl− and K+ channels, which are generally assumed to be co-located in the colonocyte apical membrane, although their exact cellular sites remain unclear. Objective T...

Intra-abdominal sepsis is frequently seen and dealt with by surgeons. It presents as a spectrum of conditions from uncomplicated localized infection through to complicated sepsis with generalized peritonitis. Complicated sepsis is frequently associated with a local and a systemic inflammatory response. The development of septic shock is associated...

Peritonitis is the term used to describe inflammation of the peritoneal cavity and, as such, may be a localized or generalized process. Peritonitis can be further classified into primary (spontaneous), secondary (due to a breach in continuity of the gastrointestinal tract), or tertiary (recurrent or persistent) (see Table 38.1).

Major liver resection is associated with impaired intestinal perfusion and intestinal ischemia, resulting in decreased mucosal integrity, increased bacterial translocation, and an increased risk of postoperative sepsis. However, the mechanism by which ischemia impairs intestinal mucosal integrity is unclear. We therefore evaluated the role of Ca(2+...

Repair of complex hernias with synthetic mesh is associated with a significant complication rate, which may necessitate mesh removal. Recent studies have reported good results with the use of collagen-based prosthesis for complicated or infected abdominal hernias. The aim of our study was to evaluate an initial experience using Permacol for the rep...

To review the current management options in inflammatory pseudotumours via analysis of ten cases from this unit the largest experience of this pathology in a Western series. To assess the medical and operative options available for this condition and the varying outcomes and the lessons learned in this unit over the time period. Data from the ten c...

Cancer arising at an ileostomy site represents a rare late complication of total colectomy performed for ulcerative colitis. There are no more than 36 published cases in the literature. We describe a case of adenocarcinoma of the mucocutaneous junction at the ileostomy site, occurring 31 years after total colectomy for ulcerative colitis. Wide exci...