Arpansinh V Parmar

• Ph.D
• Veer Narmad South Gujarat University

A new approach to improve the cloud point extraction of congo red (a hazardous anionic azo dye) from aqueous solution using Triton X-100 surfactant is reported. The interaction of congo red with Triton X-100 during micellar solubilization has also been investigated by visible absorption spectral studies. The optimum conditions for surfactant concen...

Moderately hydrophobic poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) block copolymers [Pluronics® with 20 > % PEO < 80] form micelles in water with a hydrodynamic diameter of about 20 nm. The aqueous mixed systems of Pluronics® P103, P104 and P105 [Pluronics® with molecular weight of PPO = 3250, and % of PEO 30, 40 a...

Moderately hydrophobic poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) block copolymers [Pluronics® with 20 > % PEO < 80] form micelles in water with a hydrodynamic diameter of about 20 nm. The aqueous mixed systems of Pluronics® P103, P104 and P105 [Pluronics® with molecular weight of PPO = 3250, and % of PEO 30, 40 a...

The commercially available polypropylene oxide (PPO)–polyethylene oxide (PEO) symmetrical triblock copolymers (Pluronics®) have been recognized as pharmaceutical excipients and used in a variety of applications. This paper reports studies on micellar and solubilization behavior of three PEO–PPO–PEO block copolymers, viz. P103, P104 and P105 (same P...

The effect of three ionic liquids (ILs) 1-alkyl 3-methyl imidazlolium tetraflouroborates (C(n)mim BF(4)n=4, 6, 8) on micellar solutions of an ethylene oxide-propylene oxide block copolymer (PEO-PPO-PEO), Pluronic® P103 was examined from scattering and NMR techniques. The ILs alter the cloud point and micelle size dependant on their alkyl chain leng...

Understanding the in-vitro release profile of drugs from drug eluting devices such as cardiac stent is crucial in designing and optimizing the drug embedded matrices. Sirolimus (SRL), a widely used anti-inflammatory/antiproliferative/immunosuppressive hydrophobic drug undergoes irreversible changes such as hydrolysis leading to erroneous assessment...

In present study, we have investigated the effect of an anionic surfactant sodium dodecyl sulfate (SDS) and clay on calcium alginate beads was studied to remove methylene blue (MB) and to to improve the adsorption capacity. The effects of various experimental parameters, such as shaking rate, initial dye concentration, temperature and pH on the ads...

The solubilization of four phenolic antioxidants, namely p-hydroxybenzoic acid (PHBAA), syringic acid, sinapic acid, and quercetin in micelles of an ethylene oxide (EO)-propylene oxide (PO) triblock copolymer Pluronic® P104 (EO27-PO61-EO27, PPO mol wt=3540, % PEO=40) was examined at different temperatures, pHs, and in the presence of sodium chlorid...

The present work explored the molecular implications governing the solubilization of a model drug nimesulide (NIM) in micelles of ethylene oxide-propylene oxide (EO–PO) triblock copolymers. The aggregation behavior and solubilization studies on four copolymers each with the same mol mass of central PPO block equal to 2,250 and varying % PEO was exa...

The aqueous solution behavior of a PEO–PPO–PEO block copolymer (EO103PO39EO103), was investigated in the presence of aliphatic alkanols (C2, C4, C6 and C8). The non-associated polymer chains remain extremely hydrated in water, but aggregation in the form of spherical micelles was evidenced, triggered by the interaction of polymer chains with hydrop...