Arokiyaraj Selvaraj

Seoul University

The water hyacinth Eichhornia crassipes is a rapidly growing weed that grows in shallow fresh water. It can be used for the removal of nutrients and heavy metals from water, as feedstock for biofuels, and as a bulking agent for the vermicompost process. The present study focused on the use of water hyacinth plants for nutrient and heavy metal remov...

The nutrient composition and biostimulant properties of seaweed were determined as solid biofertilizer for cultivating tomato seedlings in a greenhouse. Seaweeds (Sargassum wightii, Sargassum longifolium, Laminaria digitata, and Gelidiella acerosa) were collected from rocky areas and turned into a powder, and their nutrient compositions were analyz...

The main aim of this study is to utilize municipal solid waste (MSW) and date molasses as a culture medium to reduce the production cost of enzymes. A novel cellulase-producing fungus, Trichoderma reesei Al-K1 149, was isolated from the date molasses. MSW and date molasses were processed and used as the substrate (1:1 ratio) in solid-state fermenta...

Environmental pollution, particularly from textile industry effluents, raises concerns globally. The aim of this study is to investigate the hepatotoxicity of Sudan Black B (SBB), a commonly used textile azo dye, on embryonic zebrafish. SBB exposure led to concentration-dependent mortality, reaching 100% at 0.8 mM, accompanied by growth retardation...

The study aim was to optimise the C/N ratio, improve the compost quality, reduce pathogenic bacteria load in the compost, and improve guava yield. Vegetable wastes were mixed with cow dung, grasses, and food wastes in ratios of 4:3:2:1 (w/w) for achieving a C/N ratio of approximately 37. Co-composting is an important strategy because the mixture of...

The growing concern about pollution and toxicity in aquatic as well as terrestrial organisms is predominantly caused due to waterborne exposure and poses a risk to environmental systems and human health. This study addresses the co-toxic effects of cadmium (Cd) and ketoprofen (KPF), representing heavy metal and pharmaceutical discharge pollutants,...

The present study focuses on a facile phytosynthesis to develop C. amada-coated ZnO nanoparticles from zinc acetate dihydrate solution by using Talinum fructicosum leaf as reducing agent. The phenolic content of C. amada along with curcuminoid compounds (such as de- and bis-methoxy curcumin), function as a surface-active source to produce high-qual...

Background and Purpose Parkinson's disease (PD) is a prevalent neurodegenerative movement disorder characterized by motor dysfunction. Environmental factors, especially manganese (Mn), contribute significantly to PD. Existing therapies are focused on motor coordination, whereas nonmotor features such as neuropsychiatric symptoms are often neglected...

Enhanced fibrinolytic enzyme production was achieved by process optimization using Stenotrophomonas maltophilia AD 143 in submerged fermentation. Dairy wastewater was used as the low-cost medium. The selected bacterial strain synthesized enzymes at wide pH (7.5–8.5) and temperature ranges (35–55 °C). Scale-up experiments were carried out in a 10-L...

A series of novel 1,5-diaryl pyrazole derivatives targeting the COX enzyme were designed by combined ligand and structure-based approach. The designed molecules were then further subjected to ADMET and molecular docking studies. Out of 34 designed compounds, the top-10 molecules from the computation studies were synthesized, characterized, and eval...

This paper introduces a unique and novel method for synthesizing thienyl chalcones using iron oxide nanoparticles (FeONPs) as a heterogeneous catalyst. It stands out as a rare example in the literature for the synthesis of these chalcones from 1,3-diketones and various aromatic aldehydes. The magnetic FeONPs employed as the catalyst bring several a...

Argulus spp. infestation is a significant challenge for aquaculture, currently, there are no approved medications available to efficiently manage this parasite. Consequently, mechanical removal of parasites using forceps and natural substances like herbs are being explored as alternative treatment methods. Pellitorine (PLE) is a naturally occurring...

Paraprobiotics, known as non-viable or ghost probiotics, have attracted attention for their benefits over live microbial cells. This study was designed to investigate the paraprobiotic effects of heat-killed Bacillus coagulans on the white leg shrimp Litopenaeus vannamei. The paraprobiotic formulation was prepared in three different concentrations...

Preliminary assessment for anti-inflammatory and anti-lipidemic properties was done with different solvent extracts derived from Urtica urens and Polygonum chinense leaves through in vitro experimentation. To evaluate anti-inflammatory properties, the stability of human red blood cells membranes and the denaturation activity of proteins were assess...

17 β‐Estradiol is produced by animals, and humans and excreted through excreta, and has endocrine‐disrupting activity. Bacterial degradation is one of the suitable methods used for the removal of 17 β‐estradiol (E2) from the natural environment. In this study, E2‐degrading bacteria were screened from the enriched sediment sample from the wastewater...

Rubber tree sawdust was used as a cheap substrate for the production of enzymes in solid-state fermentation (SSF). To enhance enzyme activity and reduce the production cost of enzymes, the simultaneous production of laccase (LaC) and lignin peroxidase (LiP) from Trichoderma homatum strain NGL1 was investigated. Enzyme production was optimized by ad...

Aluminium (AL) is a strong environmental neurotoxin linked to neurodegenerative disorders. Widespread industrial use leads to its presence in water systems, causing bioaccumulation in organisms. This, in turn, results in the bioaccumulation of AL in various organisms. Several studies have highlighted the benefits of enhanced physical activity in co...

Many people have been giving various suggestions for the development of Tamil language for a long time. There is a perception that Tamil is not easy to learn and because of the abundance of Tamil characters, it is difficult to learn. On the other hand, difficulties in the usage of Scientific and technical terms in Tamil, and the demand to find prop...

The present study involved the synthesis of La2YCrO6 double perovskites using a sol–gel approach. Additionally, a sonication method was implemented to prepare La2YCrO6 double perovskites decorated on halloysites (La2YCrO6/HLNTs). The La2YCrO6/HLNTs exhibited remarkable conductivity, electrocatalytic activity, and rapid electron transfer. It is impe...

Background Polyethylene terephthalate (PET), a commonly used polymer in various food and plastic bag containers, has raised significant concerns regarding its environmental and human health risks. Despite its prevalent use, the impact of PET exposure on aquatic environments and its potential to induce neurotoxic conditions in species remain poorly...

Gut microbiota may have therapeutic effects on inflammatory bowel disease (IBD). Regulating intestinal microbiota through Lactiplantibacillus plantarum ( L. plantarum ) and faecal microbiota transplantation (FMT) is a novel approach to treating IBD. This study aimed to explore the effect of L. plantarum and FMT pretreatment in alleviating colitis i...

Shrimp farming is a significant contributor to the GDP of several growing Asian countries. However, the emergence of Enterocytozoon hepatopanaei (EHP) infection has had a negative impact on the Indian shrimp market, leading to increased mortality and growth retardation among shrimp populations. In order to address this issue, a study was conducted...

Background and Objectives: Cancer is the second-most-important deadly disease in the world, leading to severe socioeconomic consequences and posing a public threat. Consequently, breast and colorectal cancers are significant cancer types that affect women and men more commonly, respectively. Treatment failure or recurrent diseases frequently occur...

Ficus racemosa has long been used as a treatment for bacterial and fungal infections by people in India. The search for a safe alternative therapy from plant resources have gained interest in recent years due to herb’s more central place in contemporary medicine and its status as a vast global reservoir of potentially active pharmaceuticals. Using...

Shrimp is a popular commodity due to its fast growth and high economic value. However, stress-related disease outbreaks caused by intensifying agricultural practices and environmental factors have led to significant financial losses globally. Using chemical compounds to combat infectious pathogens has also led to antibiotic resistance and accumulat...

Small molecules as well as peptide-based therapeutic approaches have attracted global interest due to their lower or no toxicity in nature, and their potential in addressing several health complications including immune diseases, cardiovascular diseases, metabolic disorders, osteoporo-sis and cancer. This study proposed a peptide, GE18 of subtilisi...

Numerous conventional methods are available for analyzing various water quality parameters to determine the water quality index. However, ongoing surveillance is necessary for large bodies of water. A water quality monitoring system supports a robust surface and groundwater ecosystem. Various tactics are used to improve aquatic habitats: identifica...

We have synthesized lead tungstate (PbWO4), nickel doped PbWO4 (Ni- PbWO4) and poly ethylene glycol assisted Ni doped PbWO4 (Ni-PEG-PbWO4) by the co-precipitation method. XRD results indicate that the prepared PbWO4 based nanoparticles have a tetragonal structure. FTIR results indicated that the characterized functional groups in PEG combined well...

Butylparaben (BP), a common chemical preservative in cosmetic and pharmaceutical products, has been known to induce oxidative stress and disrupt endocrine function in humans. In contrast, morin, a flavonoid derived from the Moraceae family, exhibits diverse pharmacological properties, including anti-inflammatory and antioxidant. Despite this, the p...

Ultraviolet B wavelength ray radiation (UVB) is an environmental stressor with detrimental effects to the aquatic and human systems but also enhances adverse effects when combined with several other environmental factors such as temperature and pollution. UV rays induce cellular oxidative damage and impair motility. This study aimed to examine the...

Inflammatory Bowel Disease (IBD) is a group of persistent intestinal illnesses resulting from bowel inflammation unrelated to infection. The prevalence of IBD is rising in industrialized countries, increasing healthcare costs. Whether naturally occurring or synthetic, chalcones possess a broad range of biological properties, including anti-inflamma...

Microplastics (MP), tiny plastic particles, can be ingested by fish through their habitat or contaminated food sources. When combined with a high-fat diet (HFD), MP exposure may lead to increased MP accumulation in fish and negative impacts on their health. However, the underlying mechanisms of how MP and HFD interact to promote fat accumulation in...

Cadmium (Cd) exposure is known to cause gut inflammation. In this study, we investigated the protective effects of cordycepin, a natural compound with pharmacological properties, against gut inflammation induced by Cd exposure. Using zebrafish larvae and colon cell line models, we examined the impact of cordycepin on Cd-induced toxicity and inflamm...

Dental caries (DC)-induced pulp infections usually undergo the common endodontic treatment, root canal therapy (RCT). Endodontically treated teeth are devitalized, become brittle and susceptible for re-infection which eventually results in dental loss. These complications arise because the devitalized pulp losses its ability for innate homeostasis,...

Background Natural products are considered effective sources for new therapeutic research and development. The numerous therapeutic properties of natural substances in traditional medicine compel us to investigate the anti-cancer properties of Nimbin (N1) and its semi-natural analog Nimbic acid (N3) from Azadirachta indica against MG-63 Osteosarcom...

Diabetes Mellitus is a metabolic disease that leads to microvascular complications like Diabetic retinopathy (DR), a major cause of blindness worldwide. Current medications for DR are expensive and report multiple side effects; therefore, an alternative medication that alleviates the disease condition is required. An interventional approach targeti...

Although the toxicity of microplastics (MPs) and pesticides has recently been described, the possible effects of combining these pollutants are poorly understood. Thus, we evaluated the potential impact of exposure to polyethylene MP (PE-MP) and abamectin (ABM) (alone and combined) in zebrafish. After five days, the combined exposure to MP and ABM...

Background Bone substitutes have been used by doctors for a long time to treat osseous abnormalities. Recently, scientists have been searching for suitable materials to replace bone. Autogenous bone grafts are considered the gold standard for osseous regeneration. However, the limited availability of intraoral sources for grafting material often re...

Strontium substituted CoAl2O4 nanoparticles were prepared using a microwave combustion technique using L-alanine as a fuel. The following techniques were used to test the synthesized samples such as XRD, HR-SEM, EDX, DRS, FT-IR and VSM respectively.. Surface morphology showed nanosized crystalline grains agglomerated with flake-like and nano-sized...

Bisphenol A (BPA) leaches from plastic products have become a major inevitable concern among the research society. Human exposure to BPA leads to deleterious effects on multiple organs by the induced hyper inflammatory and oxidative stress responses. Due to the compromised antioxidant mechanism, the brain environment was highly susceptible and requ...

The structural properties of nanocrystalline spinel ferrites with chemical formula Mg0.8−xCdxFe2O4(x = 0.2, 0.4 and 0.6) prepared by combustion method and characterized by XRD, FTIR, SEM, EDX, TEM and UV studies. The X-ray diffraction (XRD) measurements confirmed the formation of a cubic spinel structure with space group Fd3m. Fourier transform inf...

AMPs are small oligopeptides acting as integral elements of the innate immune system and are of tremendous potential in the medical field owing to their antimicrobial and immunomodulatory activities. They offer a multitude of immunomodulatory properties such as immune cell differentiation, inflammatory responses, cytokine production, and chemoattra...

Epilepsy is a condition in the brain cause frequent seizures and related comorbidities. The major hindrance during the design of antiepileptic drugs is their permeability through the blood–brain barrier (BBB). Recently, advancements in biology and engineering have led to the development of nanocomposites for drug delivery through the BBB. In this s...

Background Diabetes Mellitus is a metabolic disorder characterized by insulin dysfunction or failure of the pancreatic β-cells to produce insulin resulting in hyperglycemia. Adverse effects of hyperglycemic conditions continue to be common, reducing treatment adherence. Intensified therapies are required for the constant loss of endogenous islet r...

Industrial dye waste is highly toxic, nonbiodegradable, and has a significant negative impact on the environment. Photodegradation of phenothiazine derivative dyes by undoped Fe 3 O 4 nanoparticles (Fe 3 O 4 ), reduced graphene oxide (rGO)‐doped Fe 3 O 4 nanocomposites (G@Fe 3 O 4 ), nickel‐doped Fe 3 O 4 nanoparticles (Ni@Fe 3 O 4 ), and graphene–...

Pseudomonas aeruginosa (PA) is an opportunistic pathogen that causes healthcare-associated infection and high mortality in immunocompromised patients. It produces several virulence factors through quorum sensing (QS) mechanisms that is essential for subverting host immune system. Even front-line antibiotics are unable to control PA pathogenicity du...