Arnar B. Ingason- MD PhD
- Surgery Resident at University of Vermont Medical Center
Arnar B. Ingason
- MD PhD
- Surgery Resident at University of Vermont Medical Center
About
39
Publications
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Current institution
Publications
Publications (39)
Objective
Although the mammalian heart’s ability to fully regenerate is debated, its potential to extensively repair itself is gaining support. We hypothesized that heart regeneration relies upon rapid angiogenesis to support myocardial regrowth, and sought to characterize the timeline for angiogenesis and cell proliferation in regeneration.
Metho...
Background
In recent years, increased attention has turned towards the risk of chronic opioid usage following surgery. In this nationwide cohort study, we examined the rate of new persistent opioid use following cardiac surgery via sternotomy.
Methods
All opioid-naïve patients undergoing heart surgery via sternotomy from 2005 to 2018 in Iceland, w...
Background:
Gastrointestinal bleeding (GIB) rates for direct oral anticoagulants (DOACs) and warfarin have been extensively compared. However, population-based studies comparing GIB rates among different DOACs are limited.
Objective:
To compare rates of GIB among apixaban, dabigatran, and rivaroxaban.
Design:
Nationwide population-based cohort...
In the pivotal randomized controlled trials (RCTs) for patients with atrial fibrillation, direct oral anticoagulants (DOACs) had similar or even superior efficacy and safety compared to warfarin. However, RCTs comparing different DOACs are non-existent and previous observational studies have yielded conflicting results. In this nationwide cohort st...
Background
Overall, 3-12% of opioid-naïve patients develop persistent opioid use after surgery. It’s still unclear whether persistent opioid use after transabdominal surgery is associated with adverse surgical outcomes. We aimed to assess if new persistent opioid use after transabdominal surgery is associated with increased long-term mortality and...
Background:
Previous studies have produced conflicting results regarding whether aspirin affects survival in colorectal cancer (CRC) patients. This study examines the relationship between regular aspirin use and survival in CRC patients within a nationwide cohort.
Methods:
All patients diagnosed with CRC in Iceland from 2000 to 2019 were identif...
Objectives:
Upper gastrointestinal bleeding (GIB) in patients has been well-characterized in liver cirrhosis but studies on lower GIB are limited. The clinical characteristics, management and outcomes in patients with and without liver cirrhosis was compared to determine the overall features of GIB in patients with liver cirrhosis compared with no...
Background
Surgical lung biopsy (SLB) is required for diagnosis in patients with suspected interstitial lung disease (ILD) if other less invasive diagnostic methods are non-conclusive. We evaluated the outcome of SLB by using centralized databases in a whole-nation patient-cohort.
Methods
A population-based retrospective study on 68 consecutive pa...
Objective
Previous observational studies have yielded conflicting results on whether medication adherence differs between patients receiving warfarin and direct oral anticoagulants (DOACs). Importantly, no study has adequately accounted for warfarin dosing being continuously modified based on INR values while dosing of DOACs is fixed. We aimed to c...
Gastrointestinal bleeding (GIB) is the most common type of bleeding occurring in patients on oral anticoagulation. A meta-analysis of the landmark randomized controlled trials (RCTs) for patients with atrial fibrillation demonstrated that direct oral anticoagulants (DOACs) were associated with higher GIB rates compared to warfarin. However, signifi...
Background and aims
While overall gastrointestinal bleeding (GIB) rates have been extensively compared between warfarin and direct oral anticoagulants (DOACs), it is still unclear whether upper and lower GIB rates differ between these types of drugs. This study aimed to compare upper and lower GIB rates between warfarin and DOACs in a nationwide co...
Background:
Although epistaxis is one of the most common side effects of oral anticoagulation, it is unclear whether epistaxis rates vary between different oral anticoagulants.
Objective:
To compare rates of clinically relevant epistaxis between oral anticoagulants.
Methods:
Epistaxis event rates were compared between new users of apixaban, da...
Background/aims
Causes of gastrointestinal bleeding (GIB) in patients on oral anticoagulants (OACs) are not well established. The aims of the study were to compare the causes of GIB in patients on OACs and those not on OAC therapy.
Methods
A nationwide study of all GIB events in patients on OACs in Iceland from 2014–2019 was conducted. Bleeding ev...
67-year-old female who was taking oxycodone due to chronic chest pain suffered from opioid overdose after starting treatment with voriconazole. Voriconazole is an antifungal that inhibits CYP3A4 activity in the liver. In the case reported herein, this led to higher plasma concentration of oxycodone which caused severe opioid overdose.
Although mast cell distribution has been described in both human and canine hearts, cardiac mast cells in mice have yet to be categorically localized. We therefore sought to describe mast cell distribution within the mouse heart and characterize their dependence on the Microphthalmia-associated transcription factor (Mitf). Cardiac mast cells were v...
Objectives: Gastric lipomas are rare adipose tumors that constitute less than 1% of gastric tumors. While lipomas generally do not need removal unless symptomatic, endoscopic resection has been proposed as safe for gastric lipomas smaller than 2 cm. Yet, there is no consensus on the optimal treatment method for larger lipomas. We report a case of a...
Stromal cell-derived factor 1-alpha (SDF) is a potent bone marrow chemokine capable of recruiting circulating progenitor populations to injured tissue. SDF has known angiogenic capabilities, but bone marrow-derived cellular contributions to tissue regeneration remain controversial. Bone marrow from DsRed-transgenic donors was transplanted into reci...
Background:
Unicuspid unicommissural aortic valve is an extremely rare congenital anomaly that usually presents in adulthood but can rarely present in infancy. We report a 17-year-old patient with congenital aortic stenosis secondary to unicuspid unicommissural aortic valve that was successfully treated with aortic valve replacement.
Case presenta...
Background
Diabetes mellitus is a risk factor for coronary artery disease and diabetic cardiomyopathy, and adversely impacts outcomes following coronary artery bypass grafting. Current treatments focus on macro-revascularization and neglect the microvascular disease typical of diabetes mellitus-induced cardiomyopathy (DMCM). We hypothesized that en...
