Arjun Pandian

• Ph.D
• PostDoc Position at Tshwane University of Technology

Pedalium murex commonly known as (large caltrops, bara gokhru) is a medicinal plant with potential therapeutic benefits. Hyperglycemia, a hallmark of diabetes, affects millions worldwide. Research on its leaf ethanol extract demonstrates potential for managing hyperglycemia in vitro and in vivo. Phytochemical analysis revealed secondary metabolites...

Indigofera aspalathoides is a medicinal plant with significant traditional importance, known for its anti‐inflammatory, antimicrobial, and hepatoprotective properties. In this study, the green synthesis of selenium nanoparticles (SeNPs) was performed using I . aspalathoides ethanolic extract and characterized through Fourier transform infrared spec...

One of the most important medicinal plants of India, Abutilon Indicum, is used for inflammatory joint diseases, ulcers, and scorpion bites, besides being used as antioxidant, laxative, diuretic, analgesic, and antimicrobial agent. The plant leaves’ ethanol extract was analyzed through GC-MS; the secondary metabolites were identified, and the lead m...

This study focuses on enhancing the biological activity of silver nanoparticles (AgNPs) synthesized through environmentally friendly methods. It emphasizes the importance of such approaches in nanoparticle synthesis, particularly for their potential antimicrobial applications. The research specifically investigates AgNPs synthesized from Pedalium m...

Leukoplakia, a potentially malignant oral condition, manifests as a nonremovable white lesion that is often linked to risk factors such as smoking, alcohol, and HPV. Pegylated liposomal doxorubicin (PLD), which is used in cancer treatment, has been associated with secondary oral cancers, particularly in patients with leukoplakia. A case study revea...

Type-2 Diabetes Mellitus (T2DM), one of the most common metabolic illnesses, is characterized by elevated blood sugar levels caused by impaired insulin secretion, insulin action, or both. Plant-mediated green nanomaterial production is becoming increasingly popular due to its low cost and environmental friendliness. The study’s goal is to manufactu...

The cerebellum, traditionally linked to voluntary motor coordination, is now recognized for its role in nonmotor functions, including cognitive and social behaviors. This expanded understanding is vital for identifying neurodevelopmental disorders such as autism spectrum disorder (ASD), where cerebellar abnormalities are common. Recent research has...

The Salacia reticulata, a medicinal woody climbing shrub, was utilized for our study, the green synthesis of CuO nanoparticles, which were analyzed through SEM, EDX, FTIR, XRD, and UV‒Vis spectroscopy. This study assessed the toxicity to zebrafish embryos and explored the antibacterial, cytotoxic, antidiabetic, and anti-inflammatory properties of t...

The chemical profiles of essential oils (EOs) of 7 Cinnamomum species (C. sulphuratum, C. perotettii, C. verum, C. wightii, C. camphora, C. glanduliferum, and C. malabatrum) composed from assorted parts of Western Ghats were analyzed. The antioxidant, antibacterial, and larvicidal potentialities of 7 essential oils were also investigated. Cinnamomu...

This study synthesized silver nanoparticles (AgNPs) using Vernonia amygdalina leaf extract, employing a sustainable and eco-friendly green synthesis approach. Characterization of the green-synthesized AgNPs was conducted using various analytical techniques, including UV-visible, FTIR, DLS, SEM, TEM, XRD, EDX, and assessment of their antioxidant and...

The study focuses on the green synthesis of silver nanoparticles (AgNPs) using Calotropis gigantea leaf ethanol extract, exploring their potential pharmacological applications involving biological activity. The investigation involves comprehensive characterization techniques, including UV-visible inspection, FT-IR, SEM, TEM, XRD, and EDX. Various s...

The plant Erythrina indica comes under Fabaceae family, mainly used for used in traditional medicine as nervine sedative, antiepileptic, antiasthmatic, collyrium in opthalmia, antiseptic. Current study focused synthesize of silver nanoparticles (AgNPs) by E. indica leaf ethanol extract. The green-synthesized AgNPs underwent characterization using m...

Among the diverse nanomaterials, nanoscale zero-valent iron (nZVI) particle is one of the superior materials used for the condition of remediation and environmental restoration. As a result of the nanoscale dimension of nZVI particles and its relatively high surface, it is capable of undergoing various chemical reactions, including reduction, oxida...

Silybum marianum commonly known as milk thistle is an important medicinal plant used for dyslipidemia, hyperlipidemia, cAMP phosphodiesterase inhibition, leukotriene synthesis inhibition, diabetes, chronic hepatitis, antipsoriatic activity, etc., based on current medicinal properties plant focused for the bioactive compound identification through G...

India has very prosperous plant biodiversity due to its varied climatic, altitudinal variations, and ecological habitats. Medicinal plants are an important source for various life-saving days in isolation. The affluent medicinal plant resource is disappearing at an alarming rate due to overexploitation and indiscriminate collections for their medic...

The Sesbania grandiflora is an important potential medicinal plant, medicinally used for anticancer and as an antioxidant, antimicrobial, anti-inflammatory, etc.; so for that, we focused the current study on different solvents (ethanol, methanol, and water) extracts of plant leaf for phytochemical analysis, GC-MS, synthesized silver nanoparticles c...

In this study, the authors aimed to expand a sustainable and gainful methodology for the purpose of synthesizing silver nanoparticles (AgNPs) using polyphenol bioactive compounds extracted from Eichhornia crassipes. The eco-friendliness of this method was also emphasized. The ethanol leaf extract with silver nitrate solution heated and filtered the...

Ashwagandha (Withania somnifera L. Dunal) roots have been used in Ayurveda for fever, asthma, arthritis,rheumatism, inflammation, tuberculosis, mental diseases, and male sexual disorders. Phytochemical studiesrevealed that the plant mainly contains alkaloids (withanine, sominiferine, tropine, isopelletierine andanaferine), and steroidal lactones (w...

Vinblastine, vincristine, vinleurosine, vindoline, and catharanthine are notable monoterpenoid indole alkaloids consequential from the plant periwinkle. Vinblastine, vincristine, vinleurosine, and catharanthine are anticancer compounds. Catharanthus roseus belongs to the family of Apocynaceae and has pink and white flowered, used numerous illnesses...

Sesbania grandiflora (L.) Poiret, which is a member of the Fabaceae family and is also known as Vegetable hummingbird, Agati, Katurai, or West Indian pea, has a variety of medicinal uses. As a result, the current study concentrated on phytochemical analysis and antioxidant assays (DPPH, ABTS, superoxide, and OH) of methanol, ethanol, and water extr...

The study found that C. spicatus extract had a beneficial effect on body weight and blood glucose levels in diabetic rats. Additionally, the extract contained polyphenol compounds with antioxidant, enzyme inhibition, and antiglycation activity. The blood glucose levels of the experimental groups were measured over a 28-day period, and the lipid pro...

TiO2 nanoparticles (NPs) were prepared at low temperature by stepwise hydrolysis of TiF4 in aqueous solution at 100 °C. TiO2 NPs were obtained at low temperature as small size particles. Subsequently, cobalt hexacyanoferrate (CoHCF) is adsorbed on the surface of the TiO2 NPs through the ion exchange method. This method is simple and forms TiO2/CoHC...

Parkinsonism is a progressive neurodegenerative disease of the dopaminergic neurons in the substantia nigra. Oxidative stress is a known causative factor in the death of dopaminergic neurons. Sinapic acid (SNP or SA), a hydroxycinnamic type of the abundantly available plant-derived metabolite, is known for its antioxidant and anti-inflammatory prop...

The neuroprotective effects of polyphenols have been reported in the prevention of the early onset or delay of the progression of various neurodegenerative diseases, including Parkinson disease (PD). Neuroinflammation, oxidative stress, and mitochondrial dysfunction play significant roles in the pathophysiology of PD. Sinapic acid (SNP) is a natura...

Cleome viscosa L., a member of the family Cleomaceae, is a potential medicinal plant, known for several bioactive properties such as: anticancer, antidiabetic, antioxidant, anti-inflammatory, antimi-crobial, wound healing, etc. Our study aimed to isolate a bioactive compound and assess its antibacterial activity. The crystal compound imperatorin wa...

The semiconducting copper oxide (CuO) nanostructure material is synthesized by carbon sphere used as template. The copper nitrate Cu(NO 3 ) 2 used as precursor and it has converted into CuO material like a Kernel structure with diameter 350 nm. It is applied to modify the glassy carbon electrode (GCE) for electro catalytic property of glucose and h...

The finfishes Scomberomorus guttatus and Sardinella longiceps are economically important, so selected for dissimilar sizes, proximate concern to and gross energy in relation to dissimilar seasons, size and sex groups with the vision of assessing the nutritive values like carbohydrates, proteins, lipids, energy, ash, and their % contributions, males...

The marine fishes are extremely contributes to the delivery of fatty acids, macro and micro nutrients in normal food diet, finfishes Sardinella longiceps and Scomberomorus guttatus selected for fatty acids types and minerals composition of S. longiceps, S. guttatus skin muscles were analyzed. The fatty acid composition showed quantitative differenc...

The finfishes Epinephelus malabaricus and Lutjanus argentimaculatus are cost-effectively imperative, so selected for divergent sizes, proximate compositions like crude protein, carbohydrate, lipids, ash and gross energy in relation to dissimilar seasons, size and sex groups with the vision of assessing the nutritive values and their % contributions...

Brown seaweeds are a ridiculous source of diversity of bioactive compounds, such as polyphenols, carotinoids, marine algae supply several external and internal ecological incomes. Spatoglossum asperum is a common brown seaweeds, rich sources of polyphenols, carotinoids vitamins, proteins and amino acids, polysaccharides, minerals, fibers. Its focus...

Ethnopharmacological relevance Ethnogynaecology is an emerging branch of science dealing with the treatment of gynaecological ailments by tribals, local healers, and traditional practitioners. The ethnogynaecological importance of medicinal plants in India is a fertile area to conduct more scientific studies to evaluate their potentialities, to iso...

This study used GC-MS analysis and computational biology to examine the diabetic effect of bioactive substances obtained from brown seaweed. Using AutoDock/Vina in Pymol 4.2, the molecular docking of Spatoglossum asperum on the human PPAR- protein was determined and compared to that of the well-known PPAR- agonist Gilbenclamide. The analysis the ac...

Elaeocarpus gaussenii Weibel. is a critically endangered tree species in Megamalai Wildlife Sanctuary, Southern Western Ghats, Tamil Nadu, India. This tree has been reported as an extinct and collected only by the type specimen due to poor seed germination, endosperm hardness and rigid seed coat. The present study has attempted to develop a micropr...

Marine algae have emerged as good alternative source of medical, pharmaceutical, and food industries, it’s used for anticancer, anti-inflammatory, antioxidant, antimicrobial, etc., In this study, anti-diabetic effect of brown seaweed Spatoglossum asperum was focused, We aimed systematically to examine the ethanolic extract effects of S. asperum (EE...

The current study was undertaken to investigate the composition of peroximate in relation to the types of season, sex, and group sizes in edible tissues of the finfishes of Lutjanus argentimaculatus and Epinephelus malabaricus in Nagapattinam coast of Tamil Nadu, South India. L. argentimaculatus, indeterminates are 10-40 cm, male and females are 40...

The current study was undertaken to investigate the composition of peroximate in relative to season, types of sexes, and size groups in edible tissues of finfishes of Sardinella fimbriata and Scomberomorus guttatus in Nagapattinam coast, Tamil Nadu, India. S. fimbriata, indeterminates are 4-10 cm, male and females are 11-19, in S. guttatus the inde...

Myristica fragrans (Houtt.) is an evergreen tree native to the Maluku Islands, Indonesia. M. fragrans kernel is extensively used in Indian traditional medicines to treat various diseases. Several studies attempt to compile and interpret the pharmacological potential of Myristica fragrans (Houtt.) aqueous and various chemical extracts. Thus, the pha...

Human beings are tempted to live longer and make efforts to seek successful drugs, devices and therapies to help life remain pleasurable. Biomaterials are used in safe, convenient, economically and physiologically appropriate ways to create devices. In the diagnosis of disease or damage, a number of tools and materials are being used. Elements of m...

A biomaterial is basically a substance, whether natural or manmade, that constitutes an entire or a portion of a living structure or biomedical tool that executes, performs and enhances a natural feature, which can be used for a medical application and modified for it. Biomaterials have a benign role, including to be used for a heart regulator, whi...

The plant Andrographis paniculata (Burm.f.) Nees comes under the Acanthaceae family, its widely used around the worldwide used for cold, diabetes, liver disorders, upper respiratory tract infections, snake bite, dysentery, fever, malaria, etc., An efficient protocol was established for rapid micropropagaion A. paniculata from nodal explants. MS med...

Background Strobilanthes heyneanus ( Nilgirianthus heyneanus ) belongs to the family Acanthaceae that contains many species with potential for diverse medicinal uses. It is also called ‘Karun kurinji’ and is commonly found in the South-West regions of India. The species are commonly used in rheumatic complaints, sprain of the ankle, and hernia. The...

The chemical composition of essential oil (EO) isolated from dried fruits or seeds of four spices were evaluated by gas chromatography/mass spectrometry (GC/MS) analysis. EO extraction was performed by hydrodistillation method. The results revealed that yields of EO were 0.6%, 4.5%, 1.5%, and 0.8% in coriander, cumin, fennel and Indian mustard, res...

We use a variety of species in this fast-paced environment, and algae is one of them. Algae is valuable to humans in a variety of ways. They are useful bioactive compounds that develop autotrophically. Algae are used extensively in biotechnological and medicinal applications. The study of algae components and their actions has a lot of potential in...

Cardamom is the world's most common and expensive herbal spice, which is also recognized as "the queen of spices." It is also one of the world's most ancient culinary spices with various health-promoting phytochemicals. When synthetic preservatives like sulphites, benzoates and sorbates are used as food preservatives they result in various health i...

Elettaria cardamomum is a perennial plant consisting of about seven species. It's an essential source of flavonoids, alkaloids, terpenoids, anthocyanins, and phenolic compounds with therapeutic values of antibacterial, antifungal and anti-inflammatory activities. It's used to prevent free radical formation through scavenging and suppression of chro...

Cardamom is one of the most expensive species in the world which belongs to the family Zingiberaceae and it's used as traditional medicine. Cardamom is cultivated in India, Sri Lanka, Tanzania and Guatemala. It's available in two types; black cardamom (Amomum subulatum) and green cardamom (Elettaria cardamomum). In folk medicine, different parts of...

The public health complexity globally the pathogenic Enterobacteriaceae are particularly Escherichia coli and Klebsiella pneumoniae, from the hospital samples isolates of E. coli and Klebsiella spp. 520 samples were obtained from patients in prakasam (DT), Coastal Andhra, Andhra Pradesh, India. Identified under clinical laboratory condition, for mi...

Background: Black pepper [Piper nigrum (L.), Family: Piperaceae] is used traditionally for the treatment of various diseases including; cough, cold, dyspnea throat diseases, intermittent fever, dysentery, stomachache, worms and piles. The pharmacological potential of black pepper is due to the presence of metabolites like phenolic compounds, alkalo...

The plant Ocimum gratissimum is well-known from the ancient Indian medicine system. O. gratissimum has wide variety of therapeutic applications. Folk medicine says that it can help with headaches, fevers, diarrhoea, pneumonia, and other ailments. O. gratissimum contains several bioactive constituents widely used as food additives, food colorants, p...

Tyrosinase is the key enzyme in the production of melanin. Tyrosinase inhibitors have gained interest in the cosmetics industry to prevent hyperpigmentation and skin-related disorders by inhibiting melanin production. It has been reported that several Aloe species exhibit anti-tyrosinase efficacy in vitro. In this study, the exudates of thirty-nine...

Hydroponic systems have been used as one of the standard methods for commercial production for several crops, including lettuce and tomato. Numerous hydroponic systems have been designed to study plant responses to stresses. In this study, a non-circulating hydroponic protocol that can be easily implemented in kitchen gardens for cultivation of gre...

Ashwagandha [Withania somnifera (L.) Dunal] roots have been used for Indian traditional medicine applications including for the control of fever, asthma, arthritis, rheumatism, inflammation, tuberculosis, mental diseases, and male sexual disorders. The multipurpose use of Ashwagandha has numerous other beneficial health effects that are relevant in...

Biopolymers are polymeric biomolecules that contain monomeric units which are covalently bonded to form a larger molecule. Biopolymers in nature are produced by various microorganisms and plants which require specific nutrients with a controlled environmental conditions. Biopolymers along with nanotech-nology have found many applications in various...

Bacopa monnieri (Linn.) Wettst. commonly known as waterhyssop, Brahmi plant, traditionally used for memory enhancement, nerve tonic, epilepsy, central nervous system (CNS), antidepressant, anxiety, blood pressure and antioxidant activities. Due to pharmaceutical demands its lost natural habitat. At this juncture we describe a resourceful protocol f...

Worldwide, water shortage and wastewater recycling are the foremost challenges. Agriculture and industries have been viewed as two separate sectors, both in terms of their characteristics and role in economic development. Agriculture-based industries are mainly affected due to generation of wastewater and solid wastes during their manufacturing pro...

The genus Elaeocarpus is considered as largest among the family Elaeocarpaceae recorded by ca. 360 species with significant distribution throughout the world except from Africa and America. This review provides elaborate and comprehensive details on taxonomy, phylogeny, Economic botany, phytochemistry, pharmacology, threats and conservation of Elae...

The primary producers of biomass from marine microbes are in sea, involved for carbon fixation, major nutrients recyclers are from microbes, it's compulsory for all major cycles mandatory for the prolongation of marine existence, cycling of marine microbes, bio essentials such as nitrogen, carbon, oxygen, phosphorus, iron, sulfur and other trace el...

Protection of host against environmental agents such as pathogenic micro-organisms (bacteria, fungi, and viruses) and chemicals, has been controlled by immune system, thereby preserving the integrity of the body. Adequate nutritional status should be maintained with appropriate intakes of calories, vitamins, minerals to preserve organism defense me...

The enormous stores for good green growth are the sea, oceans and investigation of kelp is called as phycology or nature. The identification and detachment of new substances are developing from the wellspring of marine creatures. The ocean growth live in salty water are eukaryotic living beings considered civilized wellspring of bioactive character...

Saussurea costus (Falc.) Lipsch. (Compositae), popularly known as Kuth in Ayurveda, is useful for gastrointestinal disorders in the form of a digestive agent, anti-gastric agent or an appetizer. Its roots have been used in respiratory problems like cough and asthma. The plant is also used in various other traditional medicinal systems including Una...

Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In humans, these viruses cause respiratory tract infections that can range from mild to lethal. Diagnostic testing to identify persons infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) infection is central to control the globa...

The present study was undertaken to analyze the influence of omega 3 Fish oil and Cod liver oil on serum cholesterol levels and triglycerides in albino wistar rats. Serum total cholesterol was determined by an enzymatic method using a diagnostic kit. HDL and LDL cholesterol were measured by an enzymatic method using automated analyzer. Triglyceride...

Coriander (Coriandrum sativum L.) is an annual, culinary, aromatic and medicinal plant. The leaves and seeds of this plant are used in food, pharmaceutical and cosmetic industries. The medicinal properties of the seeds are mainly digestion, rheumatism, joint pains and against worms. It has an array of pharmacological effects such as anticancer, ant...

The objective of this study was to examine the bioactive flavo-noids and carotenoids concentration in fifteen south Indian spice and two tree nut species using high performance liquid chromatography (HPLC). Among four flavonoids, catechin concentration was the highest in all spices and nuts and ranged between 97.1 and 1745.4 mg g À1. Quercetin conc...

Fruits and vegetables are rich source of carotenoids. The aim of this study was to find out the rapid and simple extraction method for carotenoids in grapes, blueberries, sweet potato and green chilli using HPLC analysis. Four different extraction methods; MeOH:DCM simple [methanol:dichloromethane], MeOH:DCM exhausted, MeOH simple and hexane exhaus...

The naphthoquinones and their derivatives containing hydroxyl group exhibit wide range of pharmacological activities, such as antioxidant, antibacterial, antiviral, anticancer, antimalarial, and antifungal activities. In particular, the antioxidant and anticancer behaviors of these compounds continue to draw attention of researchers. In the present...

Sesbania grandiflora (Linn.) Poiret it’s one of the important medicinal plant, comparatively studied through in vitro tissue culture technique, seeds selected, standardized in suitable MS medium for multiple in vitro shoot production by in vitro seedling increased biomass yield of calli on PGRs and different in vitro explants. Different solvent ext...

Leucas aspera (Willd.) Linn. is an important medicinal plant, efficient protocol was developed through MS medium. Leaves, node and internodes explants are used for plant tissue culture. Calli, organogenic calli, root induction was observed. Different organic solvents are used for extraction of wild plant and in vitro calli. All the extracts were fo...

Sesbania grandiflora (L.) Pers. is a common traditional medicinal plant used in bronchitis, anaemia, headache, fever, ophthalmia, nasal catarrh, leprosy, inflammation, gout and rheumatism. The present study aimed to assess plant regeneration and plantlets development in vitro using explants of S. grandiflora together with the estimation of total ph...

Background: Coriander, curry leaf and wild mint are among the most popular spices, and well known for their nutraceutical and Essential Oils (EOs) bearing properties. Objective: The present study aims to estimate total phenolic content, proline content, free radical scavenging activity, and volatile composition of the fresh leaves of coriander, cur...

Senecio candicans DC. (Asteraceae) is used as a remedy for gastric ulcer and stomach pain in the Nilgiris, district, Tamil Nadu. The present investigation was carried out to evaluate the sub-chronic toxicity of an aqueous extract of Senecio candicans (AESC) plant in Wistar albino rats. The study was conducted in consideration of the OECD 408 study...

The rising ground of indicators commerce with on combine of graphs arithmetical and supernatural graphs and the concepts are the theoretic through computational choral investigations such a variety of signals converts in to the graphs. The signals, digital and images processed and applied in different fields; in applications transportation, social,...

Leucas aspera is a high value medicinal plant in India, Java, Mauritius and Philippines. The effects of plant growth regulators effects on in vitro callus biomass accumulation and root enhancement were assessed using leaf and stem explants. Leaf and stem explants were cultured on Murashige and Skoog basal medium supplemented with different concentr...

An increasing demand of natural preservatives to increase the storage life of fresh-cut fruits and vegetables has received a great attention among researchers. The present study was conducted to evaluate quality retention and shelf-life improvement of fresh-cut apple, papaya, carrot and cucumber by chitosan-soy based edible coating. The examination...

Senecio candicans DC is an endemic sub-shrubby climber and the hot water extract of this plant is being used traditionally for the treatment of gastric ulcer. The first objective of the present study was to design a standardized protocol for in vitro regeneration of S. candicans from leaf explants and compare the antioxidant activities of aqueous e...

A series of triazolylcoumarins was synthesized by the cycloaddition of acetylenic derivatives to azide in the presence of Cu(I) catalyst at room temperature. All the synthesized compounds were evaluated for their anti-microbial activity against Gram-positive (B. subtilis and S. aureus), Gram-negative bacteria (K. pneumonia and P. vulgaris) and huma...

This study aimed to elucidate of Leucas aspera, the plant has been widely used as traditionally an antipyretic and insecticide. Different solvent extracts of L. aspera using Chicken Chorioallantoic Membrane (CAM) assay. Methanol leaf extract showed the maximum angiosuppressive activity of 3±1 inhibition, concentration-dependently displayed a strong...

Lippianodiflora (L) is an important medicinal plant used in the treatment of diseases such as Chronic indolent ulcer, gastrointestinal and respiratory disorders, diabetes etc. In the present study Nodes, internodes and leaves were used as explants for the initiation of root, shoot and callus and cultured on Murashige and Skoog (Ms) medium supplemen...

Helicteres isora dried fruit solvent extracts were evaluated for their antioxidant and anticancer activity. Acetone fruit extract H. isora showed (96.44%) strong antioxidant activity compared to hexane, and iso-propyl alcohol (IPA). Acetone extract exhibited better cytotoxicity against human lung cancer cells (NCI-H460) whereas; acetone and crude p...

Curcuma zedoaria and Curcuma amada rhizome solvent extracts were evaluated for their anticancer and antioxidant activity. The isopropyl extract of C. zedoaria exhibited high anticancer activity compared to acetone extract of C. amada. Crude protein of C. zedoaria showed good anticancer activity when compared to crude protein of C. amada. Acetone ex...