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19
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Introduction
Skills and Expertise
Current institution
Publications
Publications (19)
Background and objective: First study to assess any compensatory increase in use of non-opioid illicit substances
and alcohol in opioid dependent patients randomized to treatment with extended-release naltrexone (XR-NTX) or
buprenorphine-naloxone (BP-NLX) and in longer term treatment with extended-release naltrexone.
Method: A multicenter, outpatie...
Background:
Extended-release naltrexone (XR-NTX) is effective for illicit opioid abstinence as an opioid maintenance treatment. To improve treatment outcomes, patient's preference for the modality of treatment is an important factor.
Objectives:
We aimed to test the relationship between baseline preference for XR-NTX and adherence to treatment,...
Background and Objectives
Compare the risk of relapse to heroin and other illicit opioids among opioid-dependent patients receiving treatment with extended-release naltrexone (XR-NTX) or buprenorphine-naloxone (BP-NLX).
Methods
Re-analyzed data from a 12-week multicenter, open-label, randomized treatment study with a subsequent 36-week open-label...
Background and aim
Extended‐release naltrexone (XR‐NTX) is an underused treatment option for opioid dependence, today only available in a few countries in the world. Although effective, safe and feasible in short‐term treatment, long‐term data are scarce and there is no recommendation for required treatment length. The aims of the study were to det...
Background and objective:
Opioid maintenance treatment (OMT) is highly available in Norway, but only 50% of opioid-dependent individuals are enrolled in such programs. This study was aimed at examining if availability of extended-release naltrexone (XR-NTX) could attract individuals who for different reasons were not enrolled in an OMT program.
M...
Background and objectives:
It is presently unclear whether extended-release naltrexone hydrochloride treatment induces pain or aggravates existing pain among individuals with opioid use disorders. We assessed changes in pain among individuals receiving treatment with either extended-release naltrexone hydrochloride or buprenorphine-naloxone hydroc...
Importance
Extended-release naltrexone (XR-NTX) is a promising alternative treatment of opioid addiction but has never been compared with opioid agonist treatment for effects on symptoms of anxiety, depression, and insomnia.
Objective
To investigate whether XR-NTX unmasks or reinforces current comorbid symptoms of anxiety, depression, or insomnia...
Background and aim:
This is a follow-up study of a previously published randomized clinical trial conducted in Norway that compared extended-release naltrexone (XR-NTX) to buprenorphine-naloxone (BP-NLX) over 3 months. At the conclusion of the trial, participants were offered their choice of study medication for an additional 9 months. While BP-NL...
Importance
To date, extended-release naltrexone hydrochloride has not previously been compared directly with opioid medication treatment (OMT), currently the most commonly prescribed treatment for opioid dependence.
Objective
To determine whether treatment with extended-release naltrexone will be as effective as daily buprenorphine hydrochloride w...
Background/aims:
Treatment for addiction to illicit opioids has, thus far, been limited to 2 main approaches: maintaining physical dependence by administering opioids medically and medication-free abstinence with psychosocial support. Assisted abstinence by taking daily tablets with the opioid antagonist naltrexone is rarely practiced, but it is u...
Background
Current guidelines for opioid dependence recommend daily maintenance of physical dependence with methadone or buprenorphine, and discourage abstinence due to the high risk of relapse and overdose. Extended-release formulations of the opioid antagonist naltrexone (XR-NTX) block heroin and other opioid agonists competitively for around 4 w...
Objective To explore the effects of brief training in Motivational interviewing (MI) for medical students.
Design Video recordings of consultations between 113 final-year medical students and simulated patients were scored blind by two independent raters with the Motivational Interviewing Skill Code (MISC). Half of the students participated in a fo...
