Arhun Ali Balkan

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Verified

Arhun verified their affiliation via an institutional email.

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• B.Ed. & M.Sc. Biology
• Researcher and Ph.D candidate at Marmara University

Günümüzde kanser tedavisinde vücudun kendini savunduğu tümör karşıtı immünoterapi gibi yeni terapötik stratejiler geliştirme ihtiyacı doğmuştur. İmmünoterapide bağışıklık sisteminin vücuttaki normal hücreleri diğer savaşılacak hücre ve antijenlerden ayırmakta görevli kısımlar olarak adlandırılan immün kontrol noktaları hedef alınabilmektedir. PD-L1...

Akciğer kanseri dünyada en yaygın görülen kanserler arasında yer almaktadır. Son yıllarda, akciğer kanseri ve mikroorganizmalar arasındaki bağlantı ile ilgili çalışmalar dikkat çekmektedir. Bakteri florasındaki değişimin bazı bakterilerin oluşturduğu biyofilm tabakasının kanseri tetiklediği belirlenmiştir. Bakteriler biyofilmi oluştururken QS mekan...

S. aureus is one of the important microorganisms that cause community and hospital infections. It is specified in literary sources that QS mechanism is a bacterial communication process that leads to changes in gene expression such as producing virulence factors and forming biofilm as a response to the activation of the organism's defense mechanism...

Recently, misuse or overuse of antibiotics has led to the antibiotic resistance problem, a global healthcare problem. Most virulence factors and biofilm formation in Pseudomonas aeruginosa are controlled by quorum sensing (QS). The inhibition of QS system by inhibitor molecules has been suggested as a novel alternative antivirulence approach in whi...

Pseudomonas aeruginosa is one of the drug-resistant opportunistic pathogens with the ability to form biofilm and to produce a number of virulence factors via Quorum Sensing (QS) regulation. Most researchers have focused on QS inhibition to overcome the drug resistance problem. QS inhibitor molecules are investigated from natural resources. In the p...

Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that able to cause infections, highly invasive to poses a significant risk to global healthcare problem. The extensive use of antibiotics increases the development of multidrug resistant P.aeruginosa strains. Quorum sensing (QS) is a bacterial communication process to modify their pa...

Pseudomonas aeruginosa is an opportunistic pathogen that able to cause infections, highly invasive to poses a significant risk to public health. Quorum sensing (QS) is a bacterial communication process to modify their pattern of gene expression in response to activation of defence mechanisms via production of virulence factors and biofilm. Inhibiti...

Important to discover QS inhibitor compounds from natural sources. Cucurbita pepo has several biological activities such as antidiabetic, antitumor, antiinflammatory and anticancer. In this study, it is aimed to investigate QS inhibition and anti-biofilm effects of C. pepo against S. aureus

Pseudomonas aeruginosa is responsible for approximately 10% of all nosocomial infections and antimicrobial resistance of this bacterium is a global healthcare problem. Most virulence factors and behaviors including antimicrobial resistance and biofilm are controlled by signaling systems called Quorum Sensing (QS). Several virulence factors and rela...

Pseudomonas aeruginosa is an opportunistic and drug resistant pathogen. It is associated with high morbidity and mortality rates especially in immunocompromised patients. Quorum Sensing (QS) system is a bacterial communication system to sense their population density in their surrounding milieu via signal molecules. Several virulence factors and re...

Pseudomonas aeruginosa, opportunistic and drug resistant pathogen, is associated with high morbidity and mortality rates. Quorum Sensing (QS) system is a bacterial communication system to sense their population density in their surrounding milieu via signal molecules. Several virulence factors and related bacterial behaviors including biofilm forma...

Pseudomonas aeruginosa is one of the drug resistant opportunistic pathogens. In recent years, one of the antivirulence approaches in treatment is the inhibition of its QS systems by natural or synthetic molecules. It was reported that sunflower (Helianthus annuus), which has 3000 years of ethnobotanical value, has several biological activities. For...

In recent years, antibiotic resistant strains have become a global healthcare problem due to misuse or overuse of these drugs. P. aeruginosa is frequently encountered in the airways and hospital infections especially in patients with cystic fibrosis. The urgent need for alternative treatment strategies can be met by inhibiting Quorum Sensing mechan...

Increased drug resistance of pathogenic bacteria such as Pseudomonas aeruginosa against conventional antibiotics is a major health problem all over the world. P. Aeruginosa is responsible for approximately 10% of all nosocomial infections. P. aeruginosa regulate population behaviors such as biofilm formation and virulence by the signal mechanism ca...

Geleneksel antibiyotiklerin tedavide yetersiz kalmasına bağlı olarak, son yıllarda yeni alternatif tedavi yaklaşımı olarak QS inhibisyonu üzerinde durulmaktadır. Bitkilerin QS inhibitörü olarak kullanılabileceği ve zeytinin (Olea europaea) antimikrobiyal, antioksidan ve antikanser gibi etkileri literatürde yer aldığından; çalışmamızda zeytin yaprağ...

We studied QSI potentials of ethyl acetate cell (CE) and cell free supernatant extracts (CFSE) of extremophilic Halomonas pantelleriensis against P. aeruginosa

Pseudomonas aeruginosa infections are presented to be the main cause for high mortality rates in cystic fibrosis (CF) patients. P. aeruginosa populations can regulate their virulence gene expressions via the bacterial communication system: quorum sensing (QS). Novel approach to reduce virulence of these bacteria without risking antimicrobial resist...