Arghajit Pyne

Arghajit Pyne
Indian Institute of Technology Kharagpur | IIT KGP · Department of Chemistry

Master of Science

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27
Publications
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331
Citations

Publications

Publications (27)
Article
Dopamine (DA) and 3,4-dihydroxy-l-phenylalanine (L-Dopa or DPA), a marker and medicine for the neurological disorder Parkinson's disease (PD), lead to the formation of polymeric fluorescent nanoparticles (F-Poly NPs or F-NPs or simply, NPs). The interaction study between proteins and NPs shows prominent interaction with strong specificity toward al...
Article
Modulating the structures and properties of biomembranes via permeation of small amphiphilic molecules is immensely important, having diverse applications in cell biology, biotechnology, and pharmaceuticals, because their physiochemical and biological interactions lead to new pathways for transdermal drug delivery and administration. In this work,...
Article
The extensive and diversified applications of the well known plasmonic nanoparticle systems along with their easy and environment friendly synthetic strategies drive us to dig deep into this important research field. In the current scenario, our present study deals with an important plasmonic nanomaterial i.e. globular protein, human serum albumin...
Article
Gold nanoclusters (Au NCs) are an emerging class of fluorescent nanomaterials due to their fascinating chemical or physical properties and atomically precise structures; hence, they have been widely used in the field of biosensing and bioimaging. In this article, we demonstrate the green synthesis of orange, yellow, green and cyan emitting Au NCs b...
Article
The “Mother Nature” utilizes molecular self-assembly as an efficient tool to design several fascinating supramolecular architectures from simple building blocks like amino acids, peptides and nucleobases. The self-assembling behavior of various biologically important molecules, morphological outcomes, molecular mechanism of association and finally...
Article
One of the congenital flaws of metabolism, Phenylketonuria (PKU), is known to be related to the self-assembled toxic fibrillar aggregates of Phenylalanine (Phe) in blood at elevated concentration. Our experimental findings using L-Phenylalanine (L-Phe) at millimolar concentration suggest the formation of fibrillar morphologies in dry phase, which i...
Article
. The yellow polyphenolic pigment curcumin has many medicinal and therapeutic properties. But the lack of bioavailability prevents its widespread use as a drug. On the other hand, microemulsion possesses the capability to enhance the bioavailability of the hydrophobic drug curcumin. This molecule undergoes excited state intramolecular proton transf...
Article
The effect of neurotransmitters on the cell membrane is an elegant topic to be explored in the arena of chemistry and biology, particularly with respect to the understanding of various neurological disorders. In this present study, based on various spectroscopic and microscopic results, we find the alteration of membrane properties of model phospho...
Article
An excellent and extensive application of carbon dots (CDs) as drug delivery systems, bioimaging probes as well as different optoelectronic devices with tunable emission properties influenced us to bridge between their drug delivery and light emitting responses. In this scenario, we synthesized and purified CD from citric acid (CA) and urea using m...
Article
In this contribution, using microwave heating of polyethylene glycol (PEG 200), we have prepared carbon nanodot (CND). It is found that in aqueous medium as well as in the micellar solutions of triblock copolymer, P123 and in anionic surface active ionic liquid (SAIL), 1-butyl-3-methylimidazolium n-octylsulfate ([C 4 mim][C 8 SO 4 ]) the fluorescen...
Article
Full-text available
Literature reports suggest ample evidence of the dynamical studies of various fluorophores in different room-temperature ionic liquid (RTIL)-cosolvent mixtures. However, most of the experimental as well as simulation studies reveal...
Article
It is well reported that sugar molecules provide different types of stabilization to the biomembranes both in vitro as well as in vivo. In the present article, our focus is to investigate the interactions of two sugar molecules (sucrose and sucralose) with the lamellar structures of aerosol OT (AOT). We have attempted the structural characterizatio...
Article
Coupling of biomolecules with nanomaterials has drawn immense attraction due to the improved synergistic properties, functions and biocompatible nature. Thus this process manifests its important role and fascinating potential in various nanobiotechnogical, biomedical, biosensing and imaging applications. In this work, fundamental understanding of t...
Article
In this article, we have unveiled the aggregation behavior of a potent chemotherapeutic drug, doxorubicin hydrochloride (Dox) in a well known imidazolium based surface active ionic liquid (SAIL), 1-octyl-3-methylimidazolium chloride (C8mimCl). The aggregates formed by Dox in C8mimCl have been characterized using dynamic light scattering (DLS), fluo...
Article
Full-text available
In this article, we have investigated the excited-state intramolecular double proton transfer dynamics of [2,2′-bipyridyl]-3,3′-diol, BP(OH)2, in three alcohol–water binary mixtures, namely, ethanol (EtOH)–water, n-propanol (PrOH)–water, tert-butyl alcohol (TBA)–water, and dimethyl sulfoxide (DMSO)–water utilizing the femtosecond fluorescence upcon...
Article
In this article, we have investigated the structural and chemical effects of two sugar molecules, namely sucrose and sucralose on the structure of anionic reverse micelle (RM) AOT (aerosol-OT; sodium bis(2-ethylhexyl)sulfosuccinate)/n-heptane. The artificial sugar alternative sucralose shows very unique physical properties unlike other sugar molecu...
Article
Full-text available
We have introduced new niosome formulations using sucrose monolaurate, vitamin E and n-octanol as independent additives. Detailed characterization techniques including turbidity, dynamic light scattering, transmission electron microscopy, ξ potential, and proton nuclear magnetic resonance measurements have been introduced to monitor the morphologic...
Article
In this article, anionic, lipophilic dye Merocyanine 540(MC540) and cationic surface active ionic liquid (SAIL), 1-octyl-3-methylimidazolium chloride (C8mimCl) are employed to construct highly ordered fibrillar and vesicular aggregates exploiting ionic self-assembly (ISA) strategy. It is noteworthy that the concentration of the counterions has the...
Article
In this article, we have reported the synthesis and physicochemical characterization of a novel L-glycine amino acid derived cholesterol based surface active ionic liquid (SAIL). This SAIL has been explored for the preparation of ionic liquid (IL)-in-oil microemulsions and vesicles. The formation of IL-in-oil microemulsion is characterized by const...

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