Aravind Selvaram Thirunavukarasu

Aravind Selvaram Thirunavukarasu
Adam Mickiewicz University | UAM · Institute of Molecular Biology and Biotechnology

Master of Technology
Ongoing PhD in Laboratory of Biomolecular Interactions and Transport. Field : Structural Bioinformatics

About

6
Publications
255
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
4
Citations

Publications

Publications (6)
Poster
Brief outline of the methodology to systematically detect transport events through tunnels and benchmark with different water models. Poster also explains how water can squeeze into narrow tunnels to reach the active site and vice versa. Also some results included from TransportTools.
Poster
Full-text available
Haloalkane dehalogenase is an environmentally important biocatalyst that catalyzes the hydrolysis of the carbon-halogen bond. These are hydrolytic enzymes, requiring the presence of water molecules in their active site to perform their action. The active site of these enzymes is deeply buried, meaning that the substrate and water molecules have to...
Article
Full-text available
Information regarding pathways through voids in biomolecules and their roles in ligand transport is critical to our understanding of the function of many biomolecules. Recently, the advent of high-throughput molecular dynamics simulations has enabled the study of these pathways, and of rare transport events. However, the scale and intricacy of the...
Poster
Full-text available
Hydrolytic enzymes require the presence of water molecules in their active sites to perform their action. However, many enzymes have their active sites buried, which requires molecules of their cognate ligands and water to travel through transport pathways, called tunnels, to reach these sites. Since the tunnels relevant for water transport are oft...
Preprint
Full-text available
Information regarding pathways through voids in biomolecules and their roles in ligand transport is critical to our understanding of the function of many biomolecules. Recently, the advent of high-throughput molecular dynamics simulations has enabled the study of these pathways, and of rare transport events. However, the scale and intricacy of the...
Data
The small molecule I learnt to sulfate and crystalize used in my Master's thesis where I studied the role of halogen bonding in Lysosome and the below small molecule. ISERAC : 5-chloro-7-sulfoquinolin-1-ium-8-olate Space Group: P 1 (2), Cell: a 7.0942(4)Å b 9.6661(5)Å c 15.2024(8)Å, α 92.975(2)° β 96.394(2)° γ 107.645(2)°

Network

Cited By