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Certain activation of signaling pathways plays a great role in cancer pathogenesis and the growth and progression of the tumor cells. Among the several signaling pathways intensively entangled in cancer progression, NF-κB is one of the important pathways which are actively explored by researchers. This B cell-specific transcription factor NF-κB fam...
Chronic inflammation (CI) is a primary contributing factor involved in multiple diseases like cancer, stroke, diabetes, Alzheimer’s disease, allergy, asthma, autoimmune diseases, coeliac disease, glomerulonephritis, sepsis, hepatitis, inflammatory bowel disease, reperfusion injury, and transplant rejections. Despite several expansions in our unders...
Thiazole has widespread importance in materials and medicines. Several reviews are reported which cover essential properties of thiazoles such as pharmacological activities, structure-activity relationship studies, and various synthetic routes. However, synthesis based on a greener approaches, particularly metal-free reactions, usage of mild, nonto...