Anusree V Nair

• PhD
• Technical Assistant at Central Marine Fisheries Research Institute

Tumour necrosis factor alpha (TNF‐α) is a pivotal cytokine in vertebrate immunity. Considering the increasing scientific interest for TNF‐α in piscine biology, the paper detailed the characteristics of a novel tnf‐α gene from a high‐value mariculture species, Trachinotus blochii. The tbtnf‐α complementary DNA (cDNA) of 1385 bp encoded an open readi...

Background Interleukin 10 (IL-10) is uniquely positioned in the immune regulation of teleosts. Modifying the IL-10 pathway changes the teleost’s disease susceptibility; however, there is no data on its post-transcriptional regulation. Trachinotus blochii is a high-value mariculture species. Methods The full-length tbil-10 gene was generated throug...

Polyunsaturated fatty acids (PUFA) are vital molecules in the pharmaceutical, medical, and nutritional industries. Exploration of bacterial strains capable of producing significant amounts of PUFAs offers a promising avenue for biotechnological applications and industrial-scale production. However, an extensive screening of several samples from div...

Understanding the efficacy of antimicrobials against pathogens from clinical samples is critical for their responsible use. The manuscript presents in vitro efficacy and antimicrobial resistance (AMR) genes in seven species of fish pathogens from the disease outbreaks of Indian aquaculture against oxytetracycline, florfenicol, oxolinic acid, and en...

Antimicrobial-resistant bacteria pose serious public health risks, necessitating bioprospecting for novel antimicrobial drugs. The endophytic fungi of the mangrove ecosystem are hotspots for discovering new bioactive chemical compounds. In this context, an investigation was designed to determine the isolation of the major endophytic fungi inhabitin...

Aims To identify a marine L-asparaginase with clinically desirable attributes and characterize the shortlisted candidate through in silico tools Methods and results Marine bacterial strains (number=105) isolated from marine crabs were evaluated through a stepwise strategy incorporating the crucial attributes for therapeutic safety. The results dem...

Management of crustacean shell waste (SW) through an eco-friendly technique is an environmental obligation to control pollution. The present study showed a novel approach through the simultaneous application of proteolytic and chitinolytic bacteria to effectively degrade unprocessed crustacean SW. For this, the bacteria with concurrent chitinolytic...

A novel pretreatment process based on prioritized microbes was developed to improve the yield of reducing sugars from red (Gracilaria corticata), brown (Sargassum wightii), and green (Ulva fasciata) seaweeds as a cheap, eco-friendly method for seaweed saccharification. Prioritization of six microbes from a collection of 24 microbes was initially do...

Early and precise pathogen identification and corresponding disease management are primary concerns in aquaculture. Here, we attempted at diagnostic methods that can simultaneously identify multiple pathogens, where many samples, several pathogens, and concurrent infections are to be handled. Hence, a multiplex PCR assay targeting five major aqua...

L-asparaginase (ASNase) is the principal chemotherapeutic agent against different blood cancers. The risks associated with current clinical preparations demand screening for novel ASNases. Accordingly, the study was conducted to shortlist ASNases having clinically safer profiles from a novel niche namely, microbes in the gut and hemolymph of appare...

Red sea bream iridovirus (RSIV) is an emerging viral pathogen having significant socio-economic and environmental impacts on marine and brackish aquaculture systems. The study documents certain interesting findings of an RSIV disease outbreak that caused 50% cumulative mortality among cage farmed Asian sea bass in India. The confirmatory diagnosis...

Iron sequestration through ferritin forms a major part of innate immune response in molluscs and detailed understanding of ferritin gene and its functions can be directly applied in infection and disease management studies. Accordingly, identification and detailed molecular characterization of a ferritin subunit gene from a commercially significant...

Microbial and enzymatic processing is an attractive area for production of valuable byproducts from fish waste. Functional screening methodologies for the purpose are still based on activities in non-specific substrates, and concept of substrate specificity is not yet validated. Therefore, reliability of using non-specific substrate for the purpose...

Vibrio vulnificus, Vibrio parahaemolyticus and Vibrio harveyi are the causative agents of the most severe diseases of marine and brackish aquaculture systems. These are also associated with serious ailments in humans. The present paper unravels the virulence features/genes and antimicrobial resistance (AMR) phenotypes/genes of these Vibrio spp. iso...

Antimicrobial compounds from the safest source have gained greater relevance because of their wide spectrum of possible applications, especially in aquaculture industry, where pathogenic threat and antibacterial resistance are serious concerns. Bacillus stercoris MBTDCMFRI Ba37 isolated from mangrove environment of tropical estuarine habitats of Co...

Nonribosomal peptide synthetases (NRPS) are multi-domain enzymes that have innumerably beneficial health applications. Realizing the significance of marine microorganisms in search for NRPS sequences, study was conducted for analysis of NRPS gene sequences of marine crab haemolymph bacteria for the first time. Strains belonging to five different sp...

Bacillus subtilis MBTDCMFRI Ba37 (B. subtilis Ba37), an antibacterial strain isolated from the tropical estuarine habitats of Cochin, was evaluated for in vitro and in vivo potential, and its application as a candidate probiont in fish health management. B. subtilis Ba37 was characterized using their morphological and biochemical properties. It exh...

Antimicrobial compounds from the natural source have gained greater relevance because of their wide spectrum of possible applications, especially in the aquaculture industry where pathogenic threat and antibacterial resistance are serious concerns. In this regard, Pseudomonas aeruginosa MBTDCMFRI Ps04 (P. aeruginosa Ps04) strain isolated from the t...

In global aquaculture industry, shrimp farming plays a key role and microalgae signify a vital part. The present study focussed to analyse the influence of dietary inclusion of Aurantiochytrium sp. MBTDCMFRIJMVL1, a heterotrophic marine protist as well as co-feeding with Artemia, on the growth and survival in black tiger shrimp (Penaeus monodon). T...

Epizootic ulcerative syndrome (EUS), primarily caused by the water mold Aphanomyces invadans, is an OIE-notifiable disease, having potential impacts on fisheries. We report EUS epizootics among estuarine fishes of Kerala, India, during 2018, under post-flood conditions 3 decades after its primary outbreak. Six fish species ( Mugil cephalus , Platyc...

Epizootic ulcerative syndrome (EUS), primarily caused by Aphanomyces invadans, is an Office International des Epizootics notifiable disease, having potential impacts on fisheries. The paper reports EUS epizootics among estuarine fishes of Kerala, India, during 2018, under post-flood conditions 3 decades after its primary outbreak. Six fish species...

Epizootic ulcerative syndrome (EUS) is an epizootic ailment implicated in mass mortalities of many cultured and wild, freshwater as well as estuarine fishesof several countries. Recognizing its potential impact on fisheries sectors, Office International des Epizooties (OIE) has listed EUS as a reportable disease. Aphanomycesinvadans, the primary et...

An outbreak of skin ulcers with morbidity and mortality rate of 80% and 20% respectively, among Genetically Improved Farmed Tilapia (GIFT) sub-adults reared in a brackish water floating cage farm of Kochi, Kerala, India was reported. Bacterial isolation attempts from various internal organs (blood, kidney, liver, spleen and brain) of different dise...

Fishery Technology 56 (2019): 68-73

Bacterial diseases have turned out to be the primary constraint in sustainable aquaculture production, where, probiotics can play an important role to prevent or control fish and shellfish diseases. As the autochthonous preparations would be more effective than commercial products, continued search for novel antibacterial strains native to aquatic...

Documenting bacteria present in healthy individuals forms the first step in understanding the effects of microbial manipulation in aquaculture systems. Among the commensal microflora, gut microbiota has attracted extensive attention owing to their role in host metabolism and health maintenance. Basic knowledge on normal gut microbes within a partic...

Cultivated microalgae are an essential source of nutrition to several farmed finfish, shellfish and many other commercially significant aquaculture species. Knowledge of microalgae-associated microhabitat is important for the development of a successful, pathogen-free hatchery rearing system. Therefore, an attempt was made to isolate (1), character...

Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium having a versatile metabolic potential and great ecological and clinical significance. The geographical distribution of P. aeruginosa has revealed the existence of an unbiased genetic arrangement in terrestrial isolates. In contrast, there are very few reports about P. aeruginosa strain...

Aquaculture is one of the fastest growing food producing sector in the world. Diseases caused by bacteria are one of the major limiting factors for the sustainability of aquaculture production. Infection caused by Vibrio spp., which are the normal inhabitants of marine waters, is a major reason for severe economic loss in aquaculture industry. Vibr...

Bacillus and Pseudomonas are the dominant groups of bacteria known for their antagonistic potential against many plant and animal pathogens. Presently, exploration of these genera with antagonistic property for disease management of aquaculture system is gaining more importance to overcome the use of antibiotics and related resistance issues. Rapid...

Mortalities due to pathogenic bacteria are a major problem in aquaculture, especially in larval rearing systems. Use of antibiotics to overcome this problem is not an option any more due to the increasing antibiotic resistance among pathogens. The present study aims to understand the diversity of bacteria with antagonistic properties in the tropica...