Anuj Ranjan

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Verified

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• Ph.D
• Leading Researcher at Southern Federal University

This study provides the first comprehensive analysis of antibiotic resistance & genomic characterization of Staphylococcus saprophyticus isolated from Southern Ocean. Antibiotic susceptibility profiling of S. saprophyticus revealed complete resistance to Cefixime, Norfloxacin, Azithromycin, and Metronidazole, while susceptibility was observed for A...

Zinc (Zn) is a vital micronutrient required for optimal plant growth and soil fertility. Its use in the form of nanoparticles (NPs) has gained significant attention in agricultural applications. Green synthesized Zn‐based NPs offer an eco‐friendly solution to several conventional problems in agriculture. Several plants, bacteria, fungi and yeast ha...

Heavy metal (HM) pollution has been a significant issue for the environment and public health. Unmonitored industrial effluents are a major source of HM pollution. However, metallotolerant bacteria thriving in such environments could be potentially useful for bioremediation purposes. In this study, Bacillus cereus IEI-01 was isolated from water sam...

The integration of nanotechnology (NT) in agriculture holds immense promise for revolutionizing the way we cultivate, manage, and enhance crop production. This book chapter provides comprehensive information for assessing the multifaceted application of NT in agriculture, with a specific focus on its opportunities and associated risks to human heal...

This volume presents recent biotechnological advances in the application of extremophiles in sustainable agricultural production, plant health and soil remediation. It highlights the physiology and biochemistry of extremophiles to ensure their survival and adaptation under stressful agricultural conditions, as well as their ecological diversity and...

Probiotics, due to their multifaceted benefits to the host, are essential in medicine, agriculture, and aquaculture. The mechanisms of their action at the molecular level are complex and less explored. Both previous research and our own investigations have highlighted that incorporating probiotics into the feed of commercial fish can increase growt...

This research investigates the migration of Bisphenol A (BPA) from packaging containers into take-out vegetable soups and premixed tomato soups through three replicate studies. The samples underwent extraction using solid-phase extraction (SPE) cartridges, followed by separation on a C18 column. BPA concentrations in the soups were assessed at 15,...

The adaptation of microorganisms to extreme environmental conditions and their ability to thrive in harsh environments provide the idea of harnessing their potential for numerous applications. Their extraordinary genetic make-up and ability to thrive in harsh conditions become testimony to their utilization in differently polluted soil. Their adapt...

About 80% of the Earth’s surface consists of extreme environmental conditions that are not suitable for human life. A significant increase in atmospheric temperature is the main issue for the agricultural scientific community to protect crop plants from high temperatures. Most of the crops are sensitive to heat stresses, which cause serious problem...

Petroleum hydrocarbon (PHs) pollution is a serious environmental hazard owing to the growing concern about oil spills. To predict the possible negative consequences of oil spills and their presence in the environment, it is necessary to identify and develop regional and/or local environmentally safe limits that would take into account the local eco...

Antimicrobial properties of the new strains of micro-organisms isolated from natural sources of various ecological niches in the Moscow region and the Republic of Tatarstan were studied. Antifungal activity of isolates was detected in a test culture of toxin-producing microscopic fungi that can cause animal and plant diseases: Aspergillus flavus, C...

Gastrointestinal (GI) cancers are a significant global health concern with diverse etiologies and limited treatment options. Ellagic acid (EA), a natural polyphenolic compound, exhibits promising anticancer properties against various GI malignancies. In this article, we have reviewed recent research on the anticancer potential of EA across esophage...

To get rid of pests, insects, rodents, and fungi, pesticides are applied to crops. However, using excessive pesticides can have detrimental consequences on the environment and human health because they have a tendency to bioaccumulate at different trophic levels of an ecosystem. Besides, pesticides have been directly and indirectly linked to declin...

This study aims to assess the microbial load and heavy metals contamination in water samples from Badshahpur lake situated in Gurugram city, India across three zones. A total of 132 water samples were collected: 47 from zone 1, 40 from zone 2 and 45 from zone 3. The microbial load was quantified as total bacterial count (TBC) and concentrations of...

Gastrointestinal malignancies are one of the major worldwide health concerns. In the present review, we have assessed the plausible therapeutic implication of Ursolic Acid (UA) against gastrointestinal cancer. By modulating several signaling pathways critical in cancer development, UA could offer anti-inflammatory, anti-proliferative, and anti-meta...

This study aims to enhance lipid and biofuel productivity from Chlorella minutissima with hematite (α-Fe2O3) nanoparticles (IONPs) as a growth stimulant. The IONPs were synthesized using chemical method and characterized using X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray (EDX) analysis to confirm their st...

Currently, climate change-related environmental issues associated with agriculture is alarming and poses a potential risk to global food security, causing significant global concern as a result [...]

Soil degradation and water pollution due to intensive agriculture and industrialization are global issues and major threats to sustainable crop production. Numerous technical innovations have been used to clean up soil or increase the productivity of degraded soils and contaminated waterbodies, but since they are expensive, impractical in real-worl...

Bisphenol A (BPA) is a widely utilized chemical found in numerous everyday products, including plastic containers, food packaging, and thermal paper. Research has linked BPA exposure to a range of health concerns, encompassing developmental and reproductive issues, cancer, and obesity. Given India's status as one of the world's largest producers an...

Overuse of antibiotics is accelerating the antimicrobial resistance among pathogenic microbes which is a growing public health challenge at the global level. Higher resistance causes severe infections, high complications, longer stays at hospitals and even increased mortality rates. Antimicrobial resistance (AMR) has a significant impact on nationa...

Nanomaterials (NMs) are progressively employed in many sectors because of their novel properties; however, their introduction into the environment is of great interest to agriculture, food security, and health. Specifically, the NMs accumulation in soils could disrupt the soil and plant systems, probably posing a threat to crop yield. In this chapt...

Soilless cultivation has emerged as a fundamental alternative for large-scale vegetable production because it generates high-quality yields and uses resources efficiently. While plant growth-promoting bacteria (PGPB) are known to enhance growth and physiological aspects in crops grown in soil, their application in soilless cultivation has been rela...

Bioremediation of surfactants in water bodies holds significant ecological importance as they are contaminants of emerging concern posing substantial threats to the aquatic environment. Microbes exhibiting special ability in terms of bioremedia-tion of contaminants have always been reported to thrive in extraordinary environmental conditions that c...

Root architecture has a key role in influencing plant growth and yield. In recent years, the agriculture sector has gained interest in harnessing the potential of plant growth-promoting rhizobacteria (PGPR) that possess the competence to produce phytohormones, with the aim of enhancing these desirable traits. Phytohormone-producing PGPR exert their...

A significant portion of pesticides and fertilizers used in agriculture go unused and affect the environment in various ways. In an attempt to ensure food security, excessive usage of such agrochemicals is done. It has several detrimental impacts on the environment, human health and the economy. An improvement in the nutrient usage efficiency of fe...

Humus materials are considered complex organic substances generated through a chain of chemical reactions and responsible for many processes in soil that ultimately govern soil health. The structural and functional characteristics of humus depend upon the location, quality, and microbial abundance of the soils. However, the differential characteris...

Perfluorinated compounds (PFCs) are stable organic chemicals widely used in various industries, but their contamination in arable soils poses risks to plant growth, crop productivity, and human health. This chapter summarizes the sources, fate, uptake, and accumulation of PFCs in plants, as well as their effects on plant physiology and biochemistry...

The research investigates the escalating consumption of take-out food in India and the associated health risks stemming from the extensive use of plastic packaging. Through a comprehensive nationwide online survey, the study delved into dietary preferences, frequency of take-out food consumption, delivery service timing, and the types of packaging...

Polycyclic aromatic hydrocarbons (PAHs) are highly toxic, persistent organic pollutants that threaten ecosystems and human health. Consistent monitoring is essential to minimize the entry of PAHs into plants and reduce food chain contamination. PAHs infiltrate plants through multiple pathways, causing detrimental effects and triggering diverse plan...

Flavopiridol is a flavone synthesized from the natural product rohitukine, which is derived from an Indian medicinal plant, namely Dysoxylum binectariferum Hiern. A deeper understanding of the biological mechanisms by which such molecules act may allow scientists to develop effective therapeutic strategies against a variety of life-threatening dise...

Microalgae harvesting includes conventional methods like centrifugation, sedimentation, and filtration, as well as advanced methods like flocculation, magnetic nanoparticle, and flotation. Biomass recovery using centrifugation is high but high gravitational force can alter the cell structure. Sedimentation is one of the most useful methods in waste...

Diabetes mellitus (D.M.) is a common metabolic disorder caused mainly by combining two primary factors, which are (1) defects in insulin production by the pancreatic β-cells and (2) responsiveness of insulin-sensitive tissues towards insulin. Despite the rapid advancement in medicine to suppress elevated blood glucose levels (hyperglycemia) and ins...

The Yamuna River, a tributary of the holy Ganga, is heavily polluted in the Delhi-NCR region, India and has been gaining attention due to the excessive foaming of the river over the past few years. This can be directly or indirectly related to the overuse of surfactants and the discharge of untreated domestic and textile wastewater into the river....

Nature's Antimicrobial Arsenal: Non-Ribosomal Peptides from PGPB for Plant Pathogen Biocontrol. Fermentation 2023, 9, 597. Abstract: Non-ribosomal peptides (NRPs) are a diverse group of bioactive compounds synthesized by microorganisms, and their antimicrobial properties make them ideal candidates for use as biocontrol agents against pathogens. Non...

Antibiotic-resistant Acinetobacter baumannii, is a common pathogen found in hospital settings and has become nosocomial due to its high infection-causing tendency amongst ICU patients. The present study explores the cyanocompoundswhich were capable to inhibit the Penicillin Binding Protein of A. baumannii through molecular docking, ADMET, and molec...

Anionic surfactants in the river, particularly downstream in Delhi, have created massive foam-like conditions which may be harmful to aquatic life and humans that come in contact. The present study focussed on the quantification of anionic surfactants, biological contaminants in terms of total bacterial count, total and faecal coliform bacteria and...

In this present study, we have designed, synthetized twenty three tetra-substituted-imidazole-based fluorescent dyes that belongs to three different families of p-extended, p-fused, and nonfused tetra-substituted derivatives, to investigate their photophysical and biological properties namely anti-cancer and urease inhibitory activity. The impact o...

The increasing population density and industrialization are adversely affecting the environment globally. The contamination of the soil, agricultural lands, and water bodies with petroleum wastes and other hydrocarbon pollutants has become a serious environmental concern as perceived by the impacts on the aquatic and marine ecosystem. Various inves...

Growing concerns about antibiotic resistance in bacteria and the pursuit of novel compounds and drug candidates are significant strategies for its preparedness. The study aimed to explore Arthrospira sp. isolated from high-altitude lake water for antioxidant potential, thermal stability, and bactericidal action against various bacteria that are res...

In recent years, studies on phytochemicals, antioxidants, and antibiotics using blue green algae from harsh environments has become increasingly prevalent. The search for novel bioactive molecules exhibiting diverse biological activity is one of the most important strategies for addressing the issue of rising concerns regarding bacterial antibiotic...

The ever-increasing population, degradation of agricultural lands, use of synthetic chemicals, abrupt change in climate, and crop diseases are posing a threat to agriculture and food security, globally. Modern sustainable agricultural approaches such as nanotechnology could ensure enhanced yield and improve the quality of products without damaging...

Due to rising incidence rates of liver cancer and worries about the toxicity of current chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy has escalated. Compared to chemotherapy, quercetin, a flavonoid, is relatively less harmful to normal cells and is regarded as an excellent free-radical scavenger. Apop...

RNA viruses have been the most destructive due to their transmissibility and lack of control measures. Developments of vaccines for RNA viruses are very tough or almost impossible as viruses are highly mutable. For the last few decades, most of the epidemic and pandemic viral diseases have wreaked huge devastation with innumerable fatalities. To co...

Rapid urbanization and population growth are stressing the present agricultural systems and could threaten food security in the near future. Sustainable development in agriculture is a way out to such enormously growing food demand. Plant growth-promoting bacteria (PGPB) are considered pivotal to providing adequate nutrition and health to plants an...

Global issues such as soil deterioration, pollution, and soil productivity loss induced by industrialization and intensive agriculture pose a serious danger to agricultural production and sustainability. Numerous technical breakthroughs have been applied to clean up soil or boost the output of damaged soils, but they have failed to restore or impro...

Prolonged insulin resistance is considered one of the reasons for Type 2 Diabetes Mellitus. Upregulation of Protein tyrosine phosphatase 1B (PTP1B), a negative regulator of insulin signalling, has been well studied as a key regulator in prognosis to insulin resistance. It has been widely studied as a desirable molecular therapeutic target. The stud...

The treatment of wastewater is an expensive and energy-extensive practice that not only ensures the power generation requirements to sustain the current energy demands of an increasing human population but also aids in the subsequent removal of enormous quantities of wastewater that need to be treated within the environment. Thus, renewable energy...

Rapid urbanization is one of the key factors that leads to defragmentation and the shrinking of agricultural land. It further leads to the generation of an ample amount of municipal waste. Several technologies have emerged in the past for its utilization, and in this regard, composting is one of the conventional approaches gaining popularity in mod...

Cucurbitacins constitute a group of cucumber-derived dietary lipids, highly oxidized tetracyclic triterpenoids, with potential medical uses. These compounds are known to interact with a variety of recognized cellular targets to impede the growth of cancer cells. Accumulating evidence has suggested that inhibition of tumor cell growth via induction...

The poultry industry is generating a significant amount of waste from chicken droppings that are abundant in microbes as well as macro- and micronutrients suitable for manure. It has the potential to improve the microbial activity and nutrient dynamics in the soil, ultimately improving soil fertility. The present study aimed to investigate the effe...

Several therapies and cosmetics are available commercially to prevent or delay cell ageing, which manifests as premature cell death and skin dullness. Use of herbal products such as Aloe vera, curcumin, vitamin C-enriched natural antioxidant, and anti-inflammatory biomolecules are potential ways to prevent or delay ageing. Eggshell membrane (ESM) i...

Phytochemicals extracted from plant sources have potential remedial effects to cure a broad range of acute to severe illnesses and ailments. Quercetin is a flavonoid isolated from different dietary sources such as vegetables and fruits, exhibiting strong anti-inflammatory, anti-oxidative and non-toxic effects on the biological system. However, the...

Water scarcity due to contamination of water resources with different inorganic and organic contaminants is one of the foremost global concerns. It is due to rapid industrialization, fast urbanization, and the low efficiency of traditional wastewater treatment strategies. Conventional water treatment strategies, including chemical precipitation, me...

Eliminating organic pollutants from the environment has become a serious concern as they have become a global hazard. Such pollutants have been observed to risk the health of several flora, fauna, humans, and the overall environment. Nanoremediation for dealing with organic pollutants is a potentially novel strategy that is significantly effective...

An unbalanced diet and poor lifestyle are common reasons for numerous health complications in humans. Probiotics are known to provide substantial benefits to human health by producing several bioactive compounds, vitamins, short-chain fatty acids and short peptides. Diets that contain probiotics are limited to curd, yoghurt, kefir, kimchi, etc. How...

The rapidly growing urbanization has resulted in increased environmental pollution and degradation that has equally affected the quality of air and wastewater. Urban drains that carry wastewater from households and industries are also carrying loads of pollutants. The current study was conducted to compare the trend in the concentration of particul...

Nickel oxide nanoparticles (NiO-NPs) are extensively employed in numerous industries for different purposes. Although Ni is an essential micronutrient for the animal system but at the same time, classified as a human carcinogen by WHO and is proven hazardous to plants also at higher dosages by various studies. NiO-NPs are documented hazardous to ec...

Soil decontamination and restoration continue to be a key environmental concern around the globe. The degradation of soil resources due to the presence of heavy metals (HMs) has a substantial influence on agricultural production, food security, and human well-being, and as a result, urgent action is required. Heavy metal pollution is not a threat t...

Increasing wastewater pollution owing to the briskly rising human population, rapid industrialization, and fast urbanization has necessitated highly efficient wastewater treatment technologies. Although several methods of wastewater treatments are in practice, expensiveness, use of noxious chemicals, generation of unsafe by-products, and longer tim...

Insulin resistance (IR) is a condition of impaired response of cells towards insulin. It is marked by excessive blood glucose, dysregulated insulin signalling, altered pathways, damaged pancreatic β-cells, metabolic disorders, etc. Chronic hyperglycemic conditions leads to type 2 diabetes mellitus (T2DM) which causes excess generation of highly rea...

India is one of the world’s large and fastest-growing economies. With the expanding development, the usage of plastic for anthropogenic activities has expanded many folds and India alone generated around 3.3 million metric tonnes of plastic in the financial year 2019. 79 percent of the plastic generated worldwide enters our land, water, and environ...

Production of nanoparticles (NPs) and their use have expanded dramatically as a result along with new emerging dimensions in the field of Nanotechnology, researchers are also giving attention to environmental emissions of nanoparticles and their impacts on biotic and abiotic components. NPs presence in the environment and concern risk is increasing...

The use of surfactants in households and industries is inevitable and so is their discharge into the environment, especially into the water bodies as effluents. Being surface-active agents, their utilization is mostly seen in soaps, detergents, personal care products, emulsifiers, wetting agents, etc. Anionic surfactants are the most us ed class. T...

Nanoparticles (NPs) production and their uses have expanded dramatically as a result along with new emerging dimensions in the field of Nanotechnology (NT). Researchers are also giving attention to environmental emissions of NPs and their impacts on biotic and abiotic components. The presence of NPs in the environment and its concern risk is increa...

A significant number of nanomaterials-based products are being developed and manufactured for commercial purposes. Most of these engineered nanomaterials are disposed of in substantial quantities in the environment, including soil. Nanomaterials are also being developed specifically for application in agricultural and allied sectors. Thus, the risi...

Nanotechnology has emerged as a potential tool to enhance the agriculture, industrial manufacturing, and healthcare. Nanoparticles (NPs) have unique shape, structure, size and physicochemical characteristics that can affect the soil fertility and quality thereby affecting the normal soil microbiota and lower organism that play key roles in the crop...

Nanotechnology has offered a range of opportunities for the food sector. Unique physicochemical properties of nanoparticles (NPs) play a key role in providing the potential of enhancing agricultural produce, food processing, fortification, and packaging. Many metal NPs (e.g. Cu, Fe Zn, Mg, Mn, Se, etc.) apart from protecting plants from biotic and...

Pathogenic illnesses transmitted by food and water are a global problem with significant morbidity and mortality rates. As a consequence, monitoring these pathogens is a critical aspect of control, and more research has recently emphasized on analytical techniques to build a strategy for fast, sensitive, and accurate monitoring of food and waterbor...

Simple Summary Antimicrobial resistance (AMR) is a pressing issue worldwide that must be addressed swiftly. It is driven by spontaneous evolution, bacterial mutation, and the dissemination of resistant genes via horizontal gene transfer. Researchers are working on many novel targets, which can become a pathway to inhibit harmful bacteria. Filamento...

The increase in the number of cases of type 2 diabetes mellitus (T2DM) and the complications associated with the side effects of chemical/synthetic drugs have raised concerns about the safety of the drugs. Hence, there is an urgent need to explore and identify natural bioactive compounds as alternative drugs. Protein tyrosine phosphatase 1B (PTP1B)...

Antibiotic resistance is one of the major growing concerns for public health. Conventional antibiotics act on a few predefined targets and, with time, several bacteria have developed resistance against a large number of antibiotics. The WHO has suggested that antibiotic resistance is at a crisis stage and identification of new antibiotics and targe...

This study deals with designing and validating QSAR models generated for 45 flavonoids having PTP1B inhibition properties. Eight molecular descriptors/pharmacophoric features of each flavonoid along with their reported IC50 values against PTP1B were utilized to prepare training sets and generate models. It was developed by employing linear regressi...

The “Zero Hunger” goal is one of the key Sustainable Development Goals (SDGs) of the United Nations. Therefore, improvements in crop production have always been a prime objective to meet the demands of an ever-growing population. In the last decade, studies have acknowledged the role of photosynthesis augmentation and enhancing nutrient use efficie...

Environmental pollution is a global problem that threatens our food security. Soil is a critical component of the environment, however, the anthropogenic activity resulted in soil contamination by various kinds of pollutants. Among these notable pollutants, polyaromatic hydrocarbons (PAHs) and heavy metals (HMs) are worth mentioning. The diversity...

The advancements in nanoparticles (NPs) may be lighting the sustainable and eco-friendly path to accelerate the removal of toxic compounds from contaminated soils. Many efforts have been made to increase the efficiency of phytoremediation, such as the inclusion of chemical additives, the application of rhizobacteria, genetic engineering, etc. In th...

Microplastics (MPs) are ubiquitous and constitute a global hazard to the environment because of their robustness, resilience, and long-term presence in the ecosystem. For now, the majority of research has primarily focused on marine and freshwater ecosystems, with just a small amount of attention towards the terrestrial ecosystems. Although terrest...

The current world has many challenging situations that have to be dealt with very carefully. Among these states of affairs, the most prevailing is to discover novel sources of drugs, particularly, natural resources, which are supposed not to have adverse effects on human beings and society. During the last few decades, therefore, micro-algae are ch...