Antonios E. Koutelidakis

University of the Aegean · Department of Food Science and Nutrition

The aim of the study was to investigate whether a food frequency questionnaire is a valid tool for recording and evaluating the frequency of consumption of different functional foods in a sample of the Greek population. Ninety healthy adults aged 18-75 years, not on a specific diet for the past six months and residing in the same location during th...

Post-prandial lipemia, glycemia and oxidative stress may affect the outcome of cardiovascular disease. It has been investigated that the enhancement of spread cheese with mountain tea (Sideritis sp.) and orange peel extract, may reduce post-prandial metabolic biomarkers in healthy volunteers. The purpose of the present pilot study was to investigat...

The purpose of this randomized, retrospective study was to investigate the possible association among levels of anxiety and depression and functional food consumption frequency, Mediterranean diet adoption and anthropometric indices in a sample of Greek, mainly young, adults. One hundred twenty healthy adults, 80% of whom were 18–35 years old, were...

Background: Childhood dyslipidemia is an important risk factor for developing cardiovascular disease in adulthood. Our study aimed to investigate a possible correlation between nutritional, lifestyle, behavioral and socioeconomic factors and serum lipid levels in children with dyslipidemia. Methods: In this retrospective, observational study, in 31...

Increasing evidence indicates that the cultivation of mindful eating, adherence to the Mediterranean lifestyle, and the development of psychological resilience may contribute to the enhancement of overall health and well-being. The purpose of this study was to explore the association between mindful eating and the Mediterranean lifestyle in relatio...

Herbal infusions (HI) are a popular type of beverage known for their potential health benefits due to the extraction of phytochemicals and bioactive compounds. The Mediterranean Diet (MD) is a well-known dietary pattern with beneficial effects on health, and Psychological Resilience (PsyR) is a key indicator of mental health and human well-being. T...

Nowadays, there is a high demand in many industrial countries for healthy foods and sustainable products and so to explore innovative food technologies, such as fortification with bioactive compounds such as antioxidants and polyphenols, that may be sourced from herbs or by-products. This study’s objective was to explore the fortification of refine...

Olive oil, as the main source of polyphenols in the Mediterranean diet pattern, is mentioned to show remarkable postprandial bioactivity, contributing to the reduction of cardiometabolic risk factors. In recent years, the consumption of refined olive oil, instead of other olive oil classes, led to a reduced intake of polyphenols from the usual diet...

Nowadays, the high demand for healthy foods and sustainable products, has led the food industry to explore innovative food technologies, such as fortification with bioactive compounds like antioxidants and polyphenols, that may be sourced from herbs or by-products. The aim of the present study was to explore the enrichment of refined olive oils wit...

Olive oil, as the main source of polyphenols in the Mediterranean diet pattern, is mentioned to show remarkable postprandial bioactivity, contributing to the reduction of cardiometabolic risk factors. In recent years, the consumption of refined olive oil, instead of other olive oil classes, led to a reduced intake of polyphenols from the usual diet...

Wheat-flour crackers represent a staple snack option, although they lack nutritional value. Agricultural by-products such as olive and grape seeds, cereals such as barley and legumes such as lupine and chickpea are rich in bioactive compounds; therefore, flours obtained from those could represent a better option for bakery products fortification. T...

Background Nutrition is involved in various ways in the 17 distinct SDGs of United Nations Agenda 2030. The COVID-19 pandemic is testing the world threatening health, nutrition, education, and social protection. Objective The objective of this study was to assess the adolescents’ adherence to the Mediterranean diet that attended senior high school...

The present study is a cross-sectional study that aimed to investigate the potential associations between depression status, health-related quality of life, physical activity levels and sleep quality in a representative Greek elderly population. Three thousand four hundred five (3405) men and women over 65 years old from 14 different Greek regions...

Several Mediterranean traditional cheeses may present a beneficial effect on postprandial metabolic and inflammatory modulation due to the presence of bioactive components. The objective of the present preliminary nutritional intervention was the investigation of the postprandial metabolic responses after the intake of traditional Authentic Mytilin...

Natural Functional Foods (NFFs) are unprocessed foods with proven health benefits beyond their nutritional value. The Mediterranean Diet (MD) and Mediterranean Lifestyle (MEDILIFE) are well known for their beneficial effects on health. Psychological Resilience (PsyR) is not only an important factor in human well-being; it is also regarded as a key...

In recent decades, there has been growing interest in the fortification of dairy products with antioxidants and phenolics derived from plant byproducts and herbs. The present study focused on the analysis of dairy products, including kefir, cream cheese, yogurt, and vegan yogurt, enhanced with aqueous extracts of plant byproducts (Citrus aurantium...

The majority of recent research data has underlined that diet influences the serum lipid profile, especially triglycerides (TGs), total cholesterol (TC), low-density lipoproteins (LDL), high-density lipoproteins (HDL), and very-low-density lipoproteins (VLDL), lipid peroxidation (LPO), and a number of other parameters such as apolipoproteins (Apo),...

Introduction: The dissemination and adoption of healthy eating habits are crucial in promoting Public Health. Metabolic syndrome increases the risk of developing diabetes and cardiovascular disease, a leading cause of death. Viral hepatitis causes a high morbidity burden and a high incidence of hepatocellular carcinoma.Objective: This case-control...

Several Mediterranean functional foods and their process by-products may exert a beneficial role on hyperlipidemia, hyperglycemia, and oxidative stress modulation, providing bioactive compounds with functional properties, contributing to possible chronic disease prevention (cardiovascular disease, metabolic syndrome, obesity, diabetes mellitus, etc...

Background The aim of this study was to assess smoking prevalence among Greek adults and in sub-populations with specific sociodemographic and lifestyle determinants. Moreover, to explore the association between smoking and weight status and specific stress-related states. Methods Data from 3,820 adults (47.5% males), included in the Hellenic Nati...

The majority of recent research data has underlined that diet influences the serum lipid profile, especially triglycerides (TGs), total cholesterol (TC), low-density lipoproteins (LDL), high-density lipoproteins (HDL), and very-low-density lipoproteins (VLDL), lipid peroxidation (LPO), and a number of other parameters such as apolipoproteins (Apo),...

Several fruit by-products may exert a beneficial role on oxidative stress and inflammation modulation, providing essential bioactive components, such as polyphenols and carotenoids. Recently, the potential bioactivity of miso has been reported. The aim of this dietary intervention–clinical study was to evaluate the acute effect of a novel, function...

Wheat flour is the major constituent of bakery products consumed as everyday snacks worldwide. However, due to its poor nutritional value, high gluten content, and rapid digestion has been linked to the onset of celiac disease, obesity, diabetes type II, and metabolic syndrome. Therefore, alternative flours from olive and grape by-products as well...

Functional gastrointestinal disorders (FGIDs), such as irritable bowel syndrome, functional constipation, and functional dyspepsia, have had a high prevalence over the past few years. Recent evidence suggests that functional foods and bioactive compounds, such as probiotics and phytochemicals, may have a positive effect in treating the symptoms of...

Undoubtedly, natural products with bioactive components such as fruits and berries from the Mediterranean areas are largely appreciated and highly consumed around the world due to their significance as possible novel therapeutical agents, with immense medicinal properties and a possible profound effect on health. According to epidemiological inform...

Texas almond cultivar is a crop of significant commercial value in Greece. The present study aimed to develop a new ultrasonic‐assisted extraction method for Texas almond oil based on the Folch method for laboratory use and further evaluate its in vitro antioxidant and antiplatelet, activities as health beneficial bioactivities that further highlig...

Olive paste may exert bioactivity due to its richness in bioactive components, such as oleic acid and polyphenols. The present interventional human study investigated if the fortification of cookies with olive paste and herbs may affect postprandial lipemia, oxidative stress, and other biomarkers in healthy volunteers. In a cross-over design, 10 he...

Functional foods are considered beneficial to human health due to their high nutritional values. Currently, there is development in research to identify natural functional food sources high in bioactive compounds, such as antioxidants and polyphenols, as they are shown to contribute towards decreasing oxidative stress and maintaining well-being in...

Background In recent years, the scientific interest about the possible role of dietary attitudes on gut microbiota modulation has been increasing. Objective The present literature review aimed to analyze the effect of Mediterranean diet adoption on gut microbial composition, in comparison with the Western diet. Method From an initial number of 38...

Functional food consumption is shown to have a positive effect on anthropometric parameters and human health promotion. In addition, consumers seem to be more interested in food choices, that may have a positive effect on their health. The current study aimed to identify the antioxidant and phenolic content of naturally functional foods from the Me...

Postprandial lipemia, glycemia and oxidative stress may affect the occurrence of cardiovascular disease. The purpose of the present intervention study was to investigate the effect of a spread cheese enriched with mountain tea (Sideritis sp.) and orange peel (citrus sinensis) extract on postprandial metabolic biomarkers in healthy volunteers. In a...

Functional foods are beneficial to human health and are part of the daily diet of people trying to follow a healthier lifestyle. Olive paste is a good source of functional compounds, mainly phenolic compounds, that have been shown to have health benefits. At the same time, cookies are an ideal snack that can be fortified with additional ingredients...

Research data indicate the possible effect of both polyphenols consumption and Mediterranean diet adherence on metabolic diseases’ prevalence. The present retrospective study investigated the possible association of polyphenols mean daily intake with Mediterranean diet adherence and anthropometric indices in a sample of the Greek population. A tota...

Background The present study aimed to assess micronutrient intake among Greek adults and to identify the main food sources that contribute to it. Methods Food consumption data from 2389 participants in the Hellenic National Nutrition and Health Survey (HNNHS), collected with 24‐h recalls, was used to calculate micronutrient intakes. Usual nutrient...

Objective Diabetes mellitus is a disease associated with many complications leading to premature death. The aim of this study was to estimate prevalence of type 2 diabetes (T2D), and the proportion of the population unaware of the condition, in association with modifiable risk factors. Study design Data from the Hellenic National Nutrition and Hea...

Special Issue "Nutraceuticals: Food and Nutritional Applications"-Call for papers

Background Due to the increased burden of cardiovascular disease (CVD), country specific risk prediction models to forecast future CVD events and mortality are recommended, for primary prevention. The aim of this study was to recalibrate the HellenicSCORE, to accurately estimate the 10-year risk CVD mortality of Greek adults. Methods Data from the...

Objectives: Globally, vitamin D intake from food and supplements is low, consistent with the high prevalence of low serum 25-hydroxyvitamin D concentration. The aims of this study were to assess vitamin D intake and major relevant food contributors among Greek adults and to propose subsequent policies for intervention. Methods: Vitamin D from di...

Background & aims: Serum 25(OH)D deficiency is becoming an epidemic. The aim was to assess vitamin D status of the adult Greek population in relation to intake, sun exposure and other factors, using data from the Hellenic National Nutrition and Health Survey (HNNHS). Methods: Data from 1084 adult participants (37.8% males) were analyzed. Vitamin...

Background: Weight management and obesity prevention is a basic aim of health organizations in order to decrease the prevalence of various metabolic disorders. The aim of the present review article was the evaluation of the possible role of functional foods and their bioactive compounds as alternative way to promote weight management and prevent ob...

Background and aims: Empirically-derived dietary patterns have been shown to have both positive and adverse associations with cardiovascular disease (CVD). Yet, such associations remain unclear in the Greek population. The aim of this study was to investigate the association between empirically-derived dietary patterns and the presence of CVD and...

Background: Epidemiological studies have suggested a possible correlation between nutritional factors and gastrointestinal diseases. Methods: A case-control study was designed in order to investigate if functional foods consumption and Mediterranean diet adherence have a positive effect in ulcerative colitis, Crohn's disease, irritable bowel syndro...

Owning to the increase in the world population as well as the consumer’s awareness on the health benefits of consumption of fruits, the demand for both fresh and processed fruits has been increased. The by-product and waste streams generated from fruit processing industries are extremely diverse, owning mainly to different fruits varieties and the...

Special Issue Information Dear Colleagues, A great number of studies support that the consumption of specific conventional or processed functional foods may contribute, within a balanced diet, to the prevention of chronic diseases, such as cardiovascular diseases, hypertension, cancer, diabetes mellitus, metabolic syndrome, and neurodegenerative d...

The aim of the study was to investigate possible correlations between functional foods consumption with anthropometric parameters and body composition. 301 healthy adults aged between 18-65 years old, 181 women and 120 men from various Greek areas participated in this study. The participants completed a food frequency questionnaire (FFQ) regarding...

Honey is a food of high importance due to its nutritional value. The effect of late harvest and pollen composition on honey quality and antimicrobial activity was studied. Different physicochemical parameters were determined as quality indicators. The HMF content, diastase activity, sugar content, antimicrobial activity, and hydrogen peroxide conte...

Malnutrition is a common finding in cancer patients, which can affect disease progression and survival. This review aims to critically summarize the prognostic role of nutritional status, from Body Mass Index (BMI) and weight loss to nutrition screening tools and biochemical indices, in cancer patients. According to the currently available data, Pr...

Recently, driven by the need of finding eco-friendlier and less hazardous pigments than synthetic colorants there is an increasing trend towards their replacement with biopigments. Various types of these biopolymers (such as astaxanthin, canthaxanthin, zeaxanthin, ankaflavin, torularhodin and so on) are produced through the development of proper an...

The hypothesis that incorporation of epigallocatechin gallate (EGCG) into nanoemulsions may increase its bioactivity compared with EGCG aqueous solutions was examined in mice. After an in vitro study in a model system with stimulated gastrointestinal conditions, the following EGCG nanoemulsions were used in a mice experiment: Emulsion I: emulsion w...

The present retrospective study was conducted on 1482 women in order to evaluate whether their pre-pregnancy adherence to the Mediterranean diet may affect maternal gestational weight gain (GWG). For this purpose, the study population was classified according to the Institute of Medicine (IOM) recommendations concerning GWG. Pre-pregnancy adherence...

Functional foods and their bioactive compounds have been extensively studied as a food group of high importance in preventing the development of chronic diseases. Nowadays, cardiovascular diseases (CVD) remain the biggest cause of deaths worldwide. A great number of in vitro, animal, clinical, and epidemiological studies sup ort that the consumptio...

The vast majority of by-product streams generated throughout industrial processes arises immense environmental, societal and economic related issues. The development of strategies for the valorization of these industrial residues will not only address these problems but also promote bioeconomy, satisfying sustainable development principles. Pomegra...

Purpose: Children obesity consists a fundamental problem of public health in Greece. The understanding of the factors which is correlated to is a requirement for the implementation of intervening policy and treatment. The aim of the study was to investigate the dietary habits of the students in Lemnos Island and their correlation to obesity and ove...

pillar of high significance for human health is adequate nutrition, rich in compounds with biological action. Many epidemiologic studies have shown protective effect of plant based diets rich in phenolic compounds on cardiovascular disease, cancer, diabetes, osteoporosis and other chronic diseases. Thus, consumption of functional foods enriched wit...

Consumer increasing demand for the use of natural derived compounds and not the chemical synthesized counter parts, the awareness that agricultural practices should become more eco-friendly coupled with the increasing interest of producers to manage surplus waste streams, since the imposed fines and fees imposed to unauthorized discharges are very...

Phenolic compounds exhibit noteworthy antioxidant and antimicrobial properties and are abundant in tea and aromatic plants. In this study, we investigated the differences in the antioxidant capacity (AC) and total phenolic content (TPC) between aqueous and methanolic extracts of different types of tea (i.e. green and black tea) and aromatic plants....

Με τον όρο «λειτουργικά» εννοούμε τα τρόφιμα, επεξεργασμένα ή μη, τα οποία αποδεικνύεται, βάσει επιστημονικών μελετών, ότι λόγω των βιοδραστικών τους συστατικών συντελούν στην επίτευξη συγκεκριμένων λειτουργικών στόχων εντός του οργανισμού, συμβάλλοντας στην προαγωγή της υγείας. Μερικά από τα ερωτήματα που επιχειρείται να απαντηθούν μέσω του παρόντ...