Antonio Pose-Reino

Antonio Pose-Reino
Complejo Hospitalario Universitario de Santiago | CHUS · Internal Medicine

Professor

About

205
Publications
9,945
Reads
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2,578
Citations
Introduction
Antonio Pose-Reino currently works at the Internal Medicine, Conselleria de Sanidade. Antonio does research in Artificial Intelligence, Data Mining and Algorithms. Their current project is 'retinal microcirculation analysis.'
Additional affiliations
January 1980 - December 2018
Conselleria de Sanidade
Position
  • Head of Department

Publications

Publications (205)
Article
Background Hospitalized COVID-19 patients are prone to develop persistent symptoms and to show reduced quality of life following hospital admission. Methods Prospective cohort study of COVID-19 patients admitted to a hospital from March 1 to April 30, 2020. The primary outcome was to compare health related quality of life and persistent symptoms s...
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Background Low dose dexamethasone demonstrated clinical improvement in patients with coronavirus disease 2019 (COVID-19) needing oxygen therapy; however, evidence on the efficacy of high dose of dexamethasone is limited. Methods We performed a randomised, open-label, controlled trial involving hospitalised patients with confirmed COVID-19 pneumoni...
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Resumen Antecedentes/Contexto Existe una tendencia en los pacientes hospitalizados por COVID-19 a desarrollar síntomas persistentes y a presentar una disminución en su calidad de vida tras el ingreso hospitalario. Métodos Estudio de cohorte prospectivo de pacientes COVID-19 con ingreso hospitalario entre el 1 de marzo al 30 de abril de 2020. El o...
Article
Objectives To determine whether nutritional risk is associated with the mortality of elderly patients hospitalized with nonvalvular atrial fibrillation (NVAF).DesignProspective, multicenter cohort study.SettingInternal medicine departments in Spain.ParticipantsInpatients >75 years with NVAF.MeasurementsWe measured the thrombotic and hemorrhagic ris...
Article
Objectives To determine whether nutritional risk is associated with the mortality of elderly patients hospitalized with nonvalvular atrial fibrillation (NVAF).DesignProspective, multicenter cohort study.SettingInternal medicine departments in Spain.ParticipantsInpatients >75 years with NVAF.MeasurementsWe measured the thrombotic and hemorrhagic ris...
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Objectives To determine the prevalence of sarcopenia, frailty and cognitive impairment in elderly patients with nonvalvular atrial fibrillation (NVAF) and the factors’ influence on survival. Methods Prospective, multicentre cohort study of patients older than 75 years with NVAF hospitalised in internal medicine departments in Spain. For each patie...
Article
Resumen Objetivos Determinar la prevalencia de la sarcopenia, la fragilidad y el deterioro cognitivo en pacientes ancianos con fibrilación auricular no valvular (FANV) y su influencia en la supervivencia. Métodos Estudio de cohortes, prospectivo y multicéntrico realizado con pacientes > 75 años con FANV hospitalizados en servicios de Medicina Int...
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AimRenal insufficiency is associated with medical complications in patients with non-valvular atrial fibrillation (NVAF). However, data for elderly patients are scarce. Thus, the main objectives of the present study were to analyze the characteristics of elderly patients with NVAF and acute or chronic renal disease, describe their management in rea...
Article
In the original publication, all the collaborator names were incorrectly tagged and published online. The correct given and family names for the collaborators names should list as follows.
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Full-text available
Frailty is an important prognostic factor in older adults with cardiovascular diseases. We aim to describe the characteristics of elderly hospitalised frail patients with non-valvular atrial fibrillation (NVAF) and to assess the influence of frailty, along with other functional and health status variables on anticoagulation prescription, 1-year all...
Article
Objective To identify factors associated with poor anticoagulation control with vitamin K antagonists (VKA) among outpatients with nonvalvular atrial fibrillation (NVAF) attended in Neurology and Internal Medicine in Spain. Methods Cross-sectional and multicenter study, from the ALADIN database, of outpatients with NVAF treated with VKA and attend...
Article
Introduction: Residual cardiovascular risk remains high in patients with atherosclerotic cardiovascular disease despite current antithrombotic therapy. On the other hand, patients with atrial fibrillation have an increased risk of myocardial infarction and cardiovascular death. As a result, a new antithrombotic approach appears necessary to reduce...
Article
Objective: To identify factors associated with poor anticoagulation control with vitaminK antagonists (VKA) among outpatients with nonvalvular atrial fibrillation (NVAF) attended in Neurology and Internal Medicine in Spain. Methods: Cross-sectional and multicenter study, from the ALADIN database, of outpatients with NVAF treated with VKA and att...
Article
Aim To determine the factors associated with discontinuing or not starting oral anticoagulation (OA) therapy in older patients with non‐valvular atrial fibrillation (NVAF). Methods A prospective, multicenter cohort study was carried out of patients aged >75 years with NVAF hospitalized in internal medicine departments in Spain. For each patient, w...
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Objectives To evaluate the degree of compliance with the current guidelines regarding venous thromboembolism (VTE) prophylaxis in medical patients during admission and to identify risk factors linked to complications of VTE prophylaxis. Design Prospective cohort study. Setting The Internal Medicine Department of the University Hospital of Santiag...
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Objective: To estimate the prevalence of orthostatic hypotension (OH) in patients 80 years old and over attending a primary care unit. To relate OH to the most prevalent pathologies and to the most used drugs. Design: Transversal observational study. Location: Primary care unit, Santiago de Compostela. Participants: Eighty one patients 80 ye...
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Background Although, by itself, atrial fibrillation is associated with an impairment of quality of life antithrombotic therapy may play a role. Objective To evaluate the satisfaction with anticoagulant treatment in patients with nonvalvular atrial fibrillation who attended internal medicine departments in Spain. Methods Patients from two differen...
Article
Aim. To determine the clinical profile, management of anticoagulant treatment and satisfaction related to anticoagulation in outpatients with nonvalvular atrial fibrillation attended in Neurology or Internal Medicine departments of Spain. Patients and methods. Cross-sectional and multicenter study, in which 1,337 outpatients were included. Patients...
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Objectives: Atrial fibrillation (AF) has been associated with higher mortality. We aimed to identify the baseline predictors of in-hospital mortality among elderly patients with non-valvular AF (NVAF) hospitalised for any reason. Methods: Observational, prospective and multicentre study was carried out on patients with NVAF over the age of 75, w...
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Objective: The aim of our study is to analyse hospital readmissions due to asthma, as well as the factors associated with their increase. Study design: We carried out a retrospective study including all admissions of patients over 18 years old due to exacerbation of asthma occurring in our hospital between the years 2000 and 2010. Methods: The...
Article
Heart failure (HF) is currently one of the most significant healthcare problems in Spain and has a continuously increasing prevalence. Advances in our understanding of the various biological responses that promote cardiac remodeling and pulmonary venous congestion constitute the basis of current treatment. This article, prepared by members of the H...
Article
Heart failure (HF) is currently one of the most significant healthcare problems in Spain and has a continuously increasing prevalence. Advances in our understanding of the various biological responses that promote cardiac remodelling and pulmonary venous congestion constitute the basis of current treatment. This article, prepared by members of the...
Article
The prevalence of non-valvular atrial fibrillation (NVAF) increases with the patient's age and is associated with high morbi-mortality rates. The main goal of this study was to describe the characteristics of hospitalized elderly patients with NVAF and to identify the clinical and functional factors which determine the use of different antithrombot...
Article
Background and objetives: The prevalence of non-valvular atrial fibrillation (NVAF) increases with the patient's age and is associated with high morbi-mortality rates. The main goal of this study was to describe the characteristics of hospitalized elderly patients with NVAF and to identify the clinical and functional factors which determine the us...
Article
Objective: We have followed patients admitted to a Polypathology and Advanced Age Unit for two years in order to identify the variables that best define the mortality prognosis at medium-term (1-2years) for chronic and polypathological patients requiring admission at an Internal Medicine Department. Methods: This is an observational, prospective...
Article
Background and objective To validate the satisfaction questionnaire Anti-Clot-Treatment Scale (ACTS) in outpatients with nonvalvular atrial fibrillation (NVAF) treated with oral anticoagulants attended in Internal Medicine and Neurology departments in Spain. Methods In this cross-sectional and multicentrer study, 1337 outpatients aged ≥18 years, w...
Article
A case of a patient admitted in the internal medicine unit with a clinical picture of rhabdomyolysis, hyponatraemia and convulsions. It was probably caused by a serotonin syndrome triggered by a drug interaction between venlafaxine and amoxicillin/clavulanic acid.
Article
The increase in serum urate concentrations (hyperuricemia, ≥7.0 mg/dL) creates crystals, which promote inflammation and joint lesions. Ultrasonography can reveal these urate deposits. The presence of crystals suggests that a patient with hyperuricemia is actually experiencing asymptomatic gout, and that a patient with gout without subcutaneous toph...
Article
Background and objective: To validate the satisfaction questionnaire Anti-Clot-Treatment Scale (ACTS) in outpatients with nonvalvular atrial fibrillation (NVAF) treated with oral anticoagulants attended in Internal Medicine and Neurology departments in Spain. Methods: In this cross-sectional and multicentrer study, 1,337 outpatients aged≥18 year...
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Full-text available
Background: Several studies suggest that there is a pathogenic link between chronic obstructive pulmonary disease (COPD) and cardiovascular diseases. On the other hand, increased sympathetic tone has been described in several respiratory diseases. Our objective was to determine whether hypertension mediated by sympathetic overactivity is a mechani...
Article
The increase in serum urate concentrations (hyperuricaemia, ≥7.0mg/dL) creates crystals, which promote inflammation and joint lesions. Ultrasonography can reveal these urate deposits. The presence of crystals suggests that a patient with hyperuricaemia is actually experiencing asymptomatic gout, and that a patient with gout without subcutaneous top...
Article
Background and objective: With the development of image processing techniques, it has become possible to measure the changes in retinal vessels of hypertensive patients by means of eye fundus photographs. Patients and method: In this paper we aim to classify retinal vessels automatically into arterioles and venules. In order to do so, we have compa...
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Aims Hyponatraemia is an electrolyte disorder that occurs in advanced congestive heart failure (HF) and worsens prognosis. We explored the usefulness of tolvaptan, which has shown promising results in the treatment of this condition. Methods and results This study is based on a retrospective national registry (2011–15) of patients hospitalized wit...
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Background: Atrial fibrillation (AF) in the elderly is a complex condition. It has a direct impact on the underuse of antithrombotic therapy reported in this population. Discussion: All patients aged ≥75years with AF have an individual yearly risk of stroke >4%. However, the risk of hemorrhage is also increased. Moreover, in this population it is c...
Poster
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Resumen Objetivos: Presentar las características clínicas de los pacientes incluidos en el estudio CRONIGAL y conocer la mortalidad al año de seguimiento. Métodos: Se reclutan 698 pacientes ingresados en la planta de Medicina Interna entre junio de 2010 y julio de 2011. Se excluyen los pacientes con datos perdidos, aquellos que no firman el consent...
Poster
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Resumen Objetivos: Determinar las características diferenciales pronósticas de supervivencia a 6 meses en los pacientes crónicos y pluripatológicos ingresados en un Servicio de Medicina Interna y Pluripatología. Evaluar y comparar la performance del índice PROFUND con el índice CRONIGAL en esos pacientes. Métodos: Estudio observacional, longitudina...
Poster
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Resumen Objetivos: Comparar la utilidad de dos índices para predecir la mortalidad al cabo de un año en pacientes pluripatológicos (PP). Métodos: Se han incluido de forma prospectiva los PP dados de alta vivos tras un ingreso en una unidad de Medicina Interna de un hospital de segundo nivel. Para el diagnóstico se han utilizado los criterios de la...
Article
Full-text available
Background Atrial fibrillation (AF) in the elderly is a complex condition. It has a direct impact on the underuse of antithrombotic therapy reported in this population. Discussion All patients aged ≥75 years with AF have an individual yearly risk of stroke >4 %. However, the risk of hemorrhage is also increased. Moreover, in this population it is...
Article
Asthma remains a major public health concern because of its high prevalence and the costs it generates. Near-fatal asthma (NFA) episodes represent the most severe forms of the disease after fatal asthma with significant variations in their incidence between different populations. To analyze the episodes of NFA over a period of 11 years in the hospi...
Article
Atrial fibrillation (AF) in the elderly is a complex condition due to the high number of frequently associated comorbidities, such as cardiovascular and kidney disease, cognitive disorders, falls and polypharmacy. Except when contraindicated, anticoagulation is necessary for preventing thromboembolic events in this population. Both vitamin K antago...
Article
Full-text available
Introduction: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most frequent cause of hyponatremia in a hospital setting. However, detailed protocols and algorithms for its management are lacking. Our objective was to develop 2 consensus algorithms for the therapy of hyponatremia due to SIADH in hospitalized patients. M...
Article
Full-text available
Background: Patients with lung cancer usually present with symptoms at the time of diagnosis, but it is common that neither the doctor nor the patient initially associate them with the possibility of a malignant tumour. Objectives: The aim of our study is to analyse the symptoms of patients with lung cancer and the relationship with the personal...
Article
Hyponatraemia is the most common fluid-electrolyte disorder, and the most frequent related aetiologies are syndrome of inappropriate secretion of antidiuretic hormone (SIADH), which accounts for up to 38%. SIADH has been linked to multiple pathologies that affect the central nervous system; these disorders generally originate in the brain and, more...
Article
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most frequent cause of hyponatremia in a hospital setting. However, detailed protocols and algorithms for its management are lacking. Our objective was to develop 2 consensus algorithms for the therapy of hyponatremia due to SIADH in hospitalized patients. A multidisciplina...
Article
We report the results of hypertensive treatment over retinal arteriole narrowing in a group of 189 hypertensive patients during a 6-month treatment programme for hypertension. These patients were included in an observational study under clinical practice conditions and analysed using digital photographs of the eye fundus with a previously described...
Article
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most frequent cause of hyponatremia in a hospital setting. However, detailed protocols and algorithms for its management are lacking. Our objective was to develop 2 consensus algorithms for the therapy of hyponatremia due to SIADH in hospitalized patients. A multidisciplina...
Article
There is no agreement on the systematic exploration of the fundus oculi (FO) in hypertensive patients, and it is unknown whether the evolution of retinal microcirculatory alterations has prognostic value or not. The aim of this study was to investigate whether the evolution of the arteriole-to-venule ratio (AVR) in newly-diagnosed hypertensive pati...
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Full-text available
Timeliness of care is an important dimension of health care quality. The determining factors of less timely care and their influence on the survival of patients with lung cancer (LC) remain uncertain. To analyse the delays in the diagnosis and treatment of LC in our health area, the factors associated with the timeliness of care and their possible...
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Backgroud. To describe the clinical and epidemiological characteristics, and survival of patients with lung cancer (LC) in the Pontevedra Health Area. Methods. A retrospective observational study was conducted on all patients with a diagnosis of LC in the Pontevedra Hospital Complex (CHOP) health area over a three-year period. The data recorded inc...
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Background: To describe the clinical and epidemiological characteristics, and survival of patients with lung cancer (LC) in the Pontevedra Health Area. Methods: A retrospective observational study was conducted on all patients with a diagnosis of LC in the Pontevedra Hospital Complex (CHOP) health area over a three-year period. The data recorded...
Patent
Full-text available
Disclosed embodiments include a method for retinal image analysis implemented in a medical system with one or more processors comprising the method steps of: (a) locating an optical disk on the retinal images and establishing a plurality of circumferences centered at the disk; (b) detecting a plurality of vessels within a region defined by said cir...
Patent
Full-text available
Disclosed embodiments include a method for retinal image analysis implemented in a medical system with one or more processors comprising the method steps of: (a) locating an optical disk on the retinal images and establishing a plurality of circumferences centered at the disk; (b) detecting a plurality of vessels within a region defined by said cir...
Patent
We describe an method to develop technics for the analysis and processing of retinal images with special application to study changes in retinal microcirculation of hypertensive and diabetic patients.
Article
Full-text available
Describir las características clínicas, epidemiológicas y supervivencia de los pacientes con cáncer de pulmón (CP) en nuestra área sanitaria.PACIENTES Y METODOS: Realizamos un estudio observacional, retrospectivo, incluyendo todos los pacientes con diagnóstico de CP en el área sanitaria del Complexo Hospitalario de Pontevedra (CHOP), incluyendo tod...