Antonio Lopez

Antonio Lopez
FISABIO · Food Safety Area

PhD in Experimental Techniques in Chemistry

About

28
Publications
2,380
Reads
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253
Citations

Publications

Publications (28)
Article
Full-text available
A fast and automated strategy has been developed for identifying unknown substances in the atmosphere (concretely, in the particulate matter, PM10) using LC-HRMS (MS3). A total of 15 samples were collected in three different areas (rural, urban and industrial). A sampling flow rate of 30 m3 h−1 was applied for 24 h, sampling a total volume of aroun...
Article
Full-text available
This case study investigates the exposure of 119 Spanish women of reproductive age to 5 essential (Co, Cu, Mn, V, Zn) and 10 toxic (Ba, Be, Cs, Ni, Pb, Pt, Sb, Th, Al, U) elements and assesses their risk. The essential elements (Co, Cu, Mn, V, and Zn) showed average concentrations (GM: geometric mean) of 0.8, 35, 0.5, 0.2, and 347 μg/L, respectivel...
Article
Although Spain does not have a regular national human biomonitoring program yet, different research groups are active in evaluating the exposure of children and adults to chemicals. In the last seven years, several studies in Spain have evaluated the internal exposure of the population to currently used pesticides. The present review analyzes the s...
Article
Full-text available
The detection of SARS-CoV-2 in indoor environments is a cause of increasing concern. In this study, three sampling methodologies have been used in order to collect SARS-CoV-2 and 17 other respiratory viruses in indoor air, combined with a new analytical process to analyze respiratory viruses. Different areas of an ophthalmological hospital were inv...
Article
Full-text available
Exposure to emerging contaminants, such as phthalates, bisphenols and parabens in children has been associated with possible neurodevelopment and endocrine alterations. In the present study, the biomonitoring of biomarkers in children (5–12 years old) from the Valencia Region (Spain) have been implemented using urines from the BIOVAL program. More...
Article
A new, fast, and automatic approach has been applied for the tentative identification of unknown substances released by food contact epoxy resin after performing a migration test with food simulant. This approach combines intelligent data acquisition with AcquireX linked to LC‐Orbitrap Tribrid high‐resolution MS using data dependent‐tandem mass spe...
Article
Full-text available
This paper provides scientific results from a European LIFE project carried out in the Valencian region of Spain during the 2017 to 2018 time frame. In 2018, more than 60,000 tons of pesticides were commercialized in Spain, with approximately 15% destined for Valencian crops. In order to improve the air quality in the agricultural areas of this reg...
Article
Full-text available
A large amount of pesticide, applied mainly during agricultural practice, is released into the atmosphere, decreasing air quality and potentially causing public health problems. The Valencian region, after Andalusia, is the Spanish region with the highest consumption of pesticides owing to its large areas of agricultural land and the existence of c...
Article
Full-text available
Twenty-four substances, mainly NIAS, have been tentatively identified in food contact polycarbonate through the application a new, fast, and automated analytical strategy for the investigation of unknowns in food contact materials. Most of the identified compounds were plasticizers, slip agents, antioxidants, and ultraviolet stabilizers and fragran...
Book
Full-text available
En la presente publicación se analizan los resultados de los proyectos y programas de biomonitorización humana de contaminantes alimentarios y ambientales realizados durante el periodo 2014-2020. La evaluación de la exposición de la población a sustancias químicas es un aspecto esencial de la vigilancia de la salud que tradicionalmente se ha venido...
Article
This study assessed the inhalation risk associated with indoor pesticide concentrations in the dwellings of 41 lactating mothers living in the Valencian Region, Spain, who were participants in the BETTERMILK project. Twenty-eight substances were investigated, including pyrethroid (PYRs), organophosphate (OPPs), and organochlorine (OCPs) pesticides....
Article
This study analyzed the exposure and risk assessment of four toxic (Hg, Cd, As, Tl) and two essential (Se, Mo) elements in 119 Spanish women of reproductive age. The focus here was on the elements for which risk‐based benchmark, biomonitoring equivalents (BE), or health‐related human biomonitoring (HBM) values have already been established. All ele...
Article
Dioxins (polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF), as well as dioxin-like PCBs (dl-PCBs), are listed as persistent organic pollutants in the Stockholm Convention. In this study, we measured their concentrations in the particulate phase (PM10) of the ambient air in seven monitoring stations of the Valencian C...
Article
The main objective of the present research was to evaluate the levels of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (dl-PCBs) in the human milk of Spanish lactating women who participated in the BETTERMILK project so that exposure and risk could be assessed for these m...
Article
A new automated approach has been developed for the fast investigation of unknown substances (NIAS/IAS) in recycled LDPE plastic that could be used for food contact material (FCM). The pipeline setup includes an intelligent data acquisition with AcquireX™ linked to LC-Orbitrap Tribrid-HRMS (MS³) and coupled to Compound Discoverer data processing. T...
Poster
Phthalates are high volume produced chemicals used as plasticisers in a wide range of applications [1]. Phthalates are frequently released into the environment by leaching and migration from the products to the air, food, water and dust. Therefore, general population is continuously exposed to phthalates through ingestion, inhalation or dermal abso...
Poster
Full-text available
Control of pests and diseases in commercial crops is a permanent concern for farmers due the important yield and economic losses. Pesticides play an important role in agricultural production, preventing disease and infestation of crops. In Europe, every year around 400.000 tones of pesticide active ingredients are sold (Eurostat, 2018). As expected...
Article
Polyurethane foam (PUF) disks in passive air samplers (PAS) and passive dry deposition (Pas-DD) collectors were used to assess the presence of persistent organic pollutants (POPs) and current-use pesticides (CUPs) in a rural area of central Chile (Peumo, VI Region). The samplers were exposed from September 2015 (spring) to March 2016 (summer), with...
Article
A methodology for the sampling and determination of airborne pesticides has been developed. The trapping efficiency of three adsorbents, namely XAD-2,XAD-4 and a sandwich sorbent (PUF-XAD2-PUF), was tested for 34 pesticides and the latter was selected because it presented the highest retention capacity without breakthrough. Pesticides were determin...
Article
A hard cap espresso extraction procedure has been developed to recover airborne pesticides in particulate matter trapped in filters. This extraction step was made for 20 seconds at 72 °C and 19 bars using 50 mL of 20% (v/v) acetonitrile in water. After that, based on NaCl salting out, extracts were concentrated 22 times and analysed by ultra-high p...
Article
Outdoor air samples collected during the pesticide agricultural application period (spring and summer) from a rural community in the Centre Region (France) were analyzed to investigate temporal variation of atmospheric pesticide levels (2006–2013) and human inhalation exposure in adults, children and infants. The most frequently detected pesticides...
Article
A comprehensive retrospective analysis of pesticide metabolites in urine was developed, using liquid chromatography coupled to Orbitrap high-resolution mass spectrometry (UHPLC-HRMS) that includes both post-run target (suspect screening) and non-target screening. An accurate-mass database comprising 263 pesticide metabolites was built and used for...

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Cited By

Projects

Projects (5)
Project
Project
1. Desarrollar nuevas metodologías analíticas basadas en técnicas cromatográficas para el análisis de biomarcadores de exposición a contaminantes ambientales 2. Determinar niveles de biomarcadores de exposición a contaminantes ambientales en la población de la Comunidad Valenciana 3. Estudiar los posibles factores determianntes de la exposición a contaminantes ambientales en la población estudiada
Project
El Objetivo principal del Proyecto es el de implantar en la Comunitat Valenciana una red de vigilancia de los plaguicidas en la atmósfera. Este Objetivo principal, comprende los siguientes objetivos específicos: - Establecer un sistema de vigilancia de salud pública en relación con la presencia e impacto de los plaguicidas utilizados en la agricultura. - Implantar un sistema de indicadores que contribuyan al cumplimiento de los Reglamentos Europeos en relación con el uso sostenible de plaguicidas. - Mejorar la calidad del aire, sobre todo en relación con sustancias no reguladas y que afectan fundamentalmente a las zonas rurales - Contribuir a la creación de normas europeas sobre los niveles máximos de plaguicidas en el aire.