Antônio Lacerda-Filho

Antônio Lacerda-Filho
Federal University of Minas Gerais | UFMG · Departamento de Cirurgia

PhD

About

74
Publications
12,499
Reads
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369
Citations
Citations since 2016
19 Research Items
192 Citations
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Introduction
Experience in Medicine, with emphasis on Colorectal Surgery, acting on the following subjects: Colorectal cancer; inflammatory bowel diseases; minimally invasive surgery; defecation disorders and anal surgery.
Additional affiliations
January 1987 - present
Federal University of Minas Gerais
Position
  • Professor (Associate)

Publications

Publications (74)
Article
Background Early surgical resection is an emerging concept for patients with ileocaecal Crohn's disease (CD). The aim of this study was to compare postoperative outcomes after ileocaecal resections between patients with luminal and complicated CD. Methods A retrospective analysis of patients operated for ileocaecal CD during an 8-year period in te...
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Purpose: This study was performed to investigate the convergent validity, discriminative validity, and reliability of the Brazilian version of the low anterior resection syndrome (LARS) score in a population with low educational and socioeconomic levels. Methods: The LARS score was translated into the Portuguese language by forward- and back-tra...
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Background: Enhanced Recovery Surgical Programs were initially applied to colorectal procedures and used as multimodal approach to relieve the response to surgical stress. An important factor that negatively impacts the success of these programs is the poor tolerance of these patients to certain items in the adopted protocol, especially with regar...
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Background: Low anterior resection syndrome has a negative impact on quality of life. Intestinal irrigation is a method of lavage consisting of a scheduled evacuation. Objective: To evaluate functional and quality of life outcomes in patients with low anterior resection syndrome post transanal irrigation using a colostomy irrigation system. Des...
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Objective: to evaluate the factors associated with non-closure of protective ileostomy after anterior resection of the rectum with total mesorectum excision for rectal cancer, the morbidity associated with the closure of ileostomies and the rate of permanent ileostomy in patients with rectal adenocarcinoma. Methods: we conducted a retrospective...
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Introduction: Rectal cancer (RC) is a tumor commonly diagnosed in developing countries, accounting to the considerable rates of morbi-mortality. The neoadjuvant therapy (NT) with radiotherapy and chemotherapy plays a leading role in the management of this neoplasm, according to oncological results and the preservation of anal function. Magnetic res...
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Introduction To evaluate the combined treatment with cytoreductive surgery and intraperitoneal chemotherapy for peritoneal carcinomatosis arising from colorectal cancer, pseudomyxoma peritonei and mesothelioma. Methods Data were obtained from 73 patients with peritoneal carcinomatosis arising from colorectal cancer (52.1%), pseudomyxoma peritonei...
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The correct analysis of lymph node status is one of the most important parameters for the accurate pathological diagnosis of colorectal cancer. Our aim is to evaluate the number of lymph nodes among the specimens obtained from colorectal resections due to colorectal cancer, before and after the routine use of a lymph node revealing solution (LNRS)....
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to evaluate Crohn's disease recurrence and its possible predictors in patients undergoing surgical treatment. We conducted a retrospective study with Crohn's disease (CD) patients undergoing surgical treatment between January 1992 and January 2012, and regularly monitored at the Bowel Clinic of the Hospital das Clínicas of the UFMG. we evaluated 12...
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Context Weight loss and malnutrition are disorders observed in colorectal cancer patients. Objectives We sought to evaluate the immediate preoperative nutritional status of patients with colorectal cancer. Methods This is a cross-sectional clinical study conducted at a single center. Sixty-six consecutive patients in preoperative for elective sur...
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This study assessed male sexual function using a specific and validated questionnaire, the International Index of Erectile Function (IIEF), in patients subjected to open total mesorectal excision (OTME) and laparoscopic total mesorectal excision (LTME) and compared it with a control group. The inclusion criteria consisted of male patients with an a...
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Objetivo: embora o uso da cirurgia laparoscópica no tratamento de doenças colorretais represente um avanço significativo, é realizada atualmente em menos de um terço dos pacientes submetidos à colectomias. O objetivo desse estudo é analisar os resultados ini- ciais de cirurgias colorretais laparoscópicas vídeo-assistidas (LACS) realizadas no depart...
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Context Biofeedback has been used successfully in the treatment of fecal incontinence, working mainly on rehabilitation of the sphincter muscle. However, there are few studies presenting objective results of biofeedback, in terms of functional results and those related to the quality of life. Objectives The aims of this study was to evaluate the i...
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Objetivo este trabalho pretende comparar o perfil de pessoas octagenárias portadoras de CaCR com aquelas com idade inferior a 80 anos, no que diz respeito à distribuição por sexo, idade média dos pacientes, tempo de internação hospitalar, tipo de cirurgia realizada, complicações pós-operatórias. Métodos este trabalho foi desenvolvido pelo Serviço...
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After the introduction of total mesorectal excision (TME) and radiochemotherapy, excellent results have been achieved in the treatment of patients with rectal cancer. With better oncologic control of the disease, the functional results of this type of therapeutic approach and their impact on the quality of life (QOL) of patients started to be incre...
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INTRODUCTION: Peritoneal carcinomatosis is a condition that may be present in the natural history of colorectal cancer and some other tumors, such as pseudomyxoma peritonei. It has been associated with poor prognosis. The treatment for patients with this condition, up until recently, was systemic chemotherapy or palliative care to relieve the pain...
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Superior mesenteric artery syndrome is an entity generally caused by the loss of the intervening mesenteric fat pad, resulting in compression of the third portion of the duodenum by the superior mesenteric artery. This article reports the case of a patient with irremovable metastatic adenocarcinoma in the sigmoid colon, that evolved with intense vo...
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OBJECTIVE: Evaluate the predictive value of body mass index (BMI) for hospital length-of-stay, surgical conversion, and postoperative complications in laparoscopic colorectal surgeries. METHODS: Retrospective analysis of 152 patients undergoing laparoscopic colorectal surgery. Patients were divided into two groups: group I (BMI<30) and group II (BM...
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This report presents two cases of young males who developed the rare idiopathic form of sclerosing encapsulating peritonitis (SEP) presented as partial bowel obstruction, both diagnosed during surgical treatment, with satisfactory outcomes. Sclerosing encapsulating peritonitis is a rare and enigmatic condition, characterized by intraperitoneal fibr...
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Although colorectal cancer is typical in the older population, tumor onset before age 40 is not infrequent. However, the behavior, characteristics, and prognosis of this disease in young patients are unclear when compared to the older population. It is believed that young patients have a poor prognosis. We hypothesized that young patients have a po...
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INTRODUCTION: The incidence and mortality of colorectal cancer (CRC) have shown, worldwide, an upward trend, particularly in developed countries and urban areas of developing countries. The study of tumor's pathological characteristics is important for staging and the definition of the proper therapy to be used. The aim of this study is to evaluate...
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The role of drugs that intervene with the tirosine kinase activity on the c-kit receptors in the treatment of gastrointestinal stromal tumors (GISTs) has been considered very important, mainly in large tumors. We report a case of a male patient, 56 years-old, obese, presenting with feeling of rectal pressure and incomplete evacuation. Work-up revea...
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We have proposed a simplified perioperative rehabilitation program for elective colonic surgery that is focused on early oral nutrition and that could reduce hospital stay and postoperative ileus time without raising complications and readmission rates. Fifty-four patients admitted for elective colonic surgery were prospectively randomized into two...
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This is the first Brazilian Consensus on inflammatory bowel disease, carried out by the Brazilian Study Group of Inflammatory Bowel Disease, and discusses the treatment of Crohn's disease and ulcerative colitis in acute and remission phases. The first part of the text, brings out a review on the main drugs used in the treatment of inflammatory bowe...
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INTRODUCTION: Colorectal laparoscopic surgery is considered a procedure with long learning curve. Despite surgeons with experience in laparoscopic surgery are able to achieve the same oncological results obtained in open procedures, it is important to evaluate if these good results are sustained during the learning curve. The aim of this study was...
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Tem sido demonstrado que o número de linfonodos obtidos em peças cirúrgicas de câncer colorretal é fundamental para o adequado estadiamento da doença e, consequentemente, para a obtenção de melhores resultados oncológicos. A percepção de diferenças no número de linfonodos dissecados em peças cirúrgicas de câncer colorretal pelos mesmos cirurgiões e...
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INTRODUCTION: Several studies, including meta-analysis, have demonstrated the safety, effectiveness and oncologic equivalence of laparoscopic resections when compared to open procedures leading minimally invasive colorectal surgery to be adopted in crescent number of services around the world. This study aims to evaluate the quality of life of pati...
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O carcinoma da próstata é uma doença freqüente em idosos e em casos avançados pode invadir o reto, simulando um carcinoma primário deste órgão. Nestas situações, a maioria dos pacientes apresenta sintomas retais exuberantes e sintomas urinários leves ou ausentes. É relatado um caso de um paciente com diagnóstico de tumor de próstata localmente agre...
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INTRODUCTION: Since 1991, laparoscopic surgery started to be considered in the treatment of colorectal disease. With the improvement of the technique and the confirmation of the benefits shown in several studies, the perspective of laparoscopy has changed. Recently, the oncologic resections were recognized as a viable alternative, with similar resu...
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INTRODUCTION: Several studies, including meta-analysis, have demonstrated the safety, effectiveness and oncologic equivalence of laparoscopic resections when compared to open procedures leading minimally invasive colorectal surgery to be adopted in crescent number of services around the world. This study aims to evaluate the quality of life of pati...
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Full-text available
INTRODUCTION: Colorectal laparoscopic surgery is considered a procedure with long learning curve. Despite surgeons with experience in laparoscopic surgery are able to achieve the same oncological results obtained in open procedures, it is important to evaluate if these good results are sustained during the learning curve. The aim of this study was...
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Full-text available
Prostate carcinoma is a frequent disease in the elderly and in advanced cases it can cause rectal invasion mimicking a primary rectal carcinoma. Most of patients present with significant rectal symptoms and mild to absent urinary tract symptoms. We report a case of a patient with a very aggressive locally invasive prostate carcinoma with a concomit...
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It has been demonstrated that lymph nodes harvest from surgical specimens of colorectal cancer is one of the most important features for appropriate staging of the disease and to plain the best treatment. The perception of differences in the number of harvest lymph nodes in surgical specimens of colorectal cancer by the same surgeons in different h...
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OBJECTIVE: To study was to investigate the associated morbidity and mortality of the restoration of intestinal continuity after Hartmann's procedure. METHODS: Hospital records of 29 patients undergoing surgery to restoration of intestinal continuity after Hartmann's procedure at Hospital das Clínicas da Universidade Federal de Minas Gerais between...
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To study was to investigate the associated morbidity and mortality of the restoration of intestinal continuity after Hartmann's procedure. Hospital records of 29 patients undergoing surgery to restoration of intestinal continuity after Hartmann's procedure at Hospital das Clínicas da Universidade Federal de Minas Gerais between January 1998 and Dec...
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INTRODUÇÃO: A avaliação anátomo-patológica do câncer colorretal (CCR) em relação ao acometimento linfonodal é fundamental para o prognóstico da doença e para a indicação de terapias adjuvantes. Tem sido considerado um número mínimo de 12 linfonodos na peça cirúrgica para que se obtenha adequado estadiamento linfonodal, embora se admita que quanto m...
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INTRODUCTION: Accurate pathological study of colorectal cancer (CRC) specimens is of paramount importance to prognosis and indication of adjuvant therapies. Despite the minimum of 12 lymph nodes has been considered adequate to correctly establish the stage of disease, a bigger harvest of lymph nodes would increase the number of metastatic lymph nod...
Article
Intestinal intussusception in adult patients is rare. In contrast with paediatric patients, it is usually secondary to a definable lesion, often malignant. The purpose of this study was to determine the causes and the management of intussusception in adult patients. A retrospective review was performed looking at patients over 18 years with intesti...
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A retocele é uma projeção sacular anormal da parede retal, de etiologia multifatorial e uma causa muito significativa de sintomas anorretais como plenitude retal, sensação de peso anal durante a defecação, evacuação incompleta e dor retoanal. Muito tem se discutido sobre retoceles em mulheres, mas poucas publicações têm mencionado a presença de ret...
Article
A retocele é uma projeção sacular anormal da parede retal, de etiologia multifatorial e uma causa muito significativa de sintomas anorretais como plenitude retal, sensação de peso anal durante a defecação, evacuação incompleta e dor retoanal. Muito tem se discutido sobre retoceles em mulheres, mas poucas publicações têm mencionado a presença de ret...
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INTRODUÇÃO: Mucocele do apêndice (MA) é uma lesão rara, caracterizada pelo acúmulo de secreção mucoíde em sua luz. Diagnóstico precoce é fundamental para evitar o extravasamento de secreção mucoíde na cavidade peritoneal, causando pseudomixoma peritoneal. RELATO DE CASO: Paciente sexo masculino, 62 anos com história de dor abdominal em fossa ilíaca...
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Diagnosis of subtypes of chronic constipation has been considered difficult to achieve even in specialized centers. Although colorectal physiologic tests have brought an important contribution, it remains unclear in which patients these tests should be indicated for. This study aims to establish a differential diagnosis for chronic constipation cas...
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Introduction: Appendiceal mucocele (AM) is a rare lesion that is characterized by an appendiceal lumen distended with mucus. Early diagnosis and prompt surgical intervention are mandatory to prevent spillage of the mucinous content into the peritoneal cavity, causing pseudomyxoma peritonei. Case report: A 62-year-old nude was presented with a 6-mon...
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A intussuscepção intestinal em adultos é rara. Ao contrário do que ocorre na faixa pediátrica, é, na maioria das vezes, secundária a uma lesão definida com potencial significativo de malignidade. O objetivo deste estudo é avaliar retrospectivamente os aspectos diagnósticos e terapêuticos da intussuscepção intestinal em adultos. Foram estudados, ret...
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The Tailgut Cyst is an embryological remnant of the hindgut that can be a part of the Currarino Syndrome. Report of a case: A 43-year-old woman with lombalgy, urine retain and presacral mass. Preceding history of ectopic anus, constipation associated with congenital megacolon. Imaging exams indicate retrorectal cyst that compresses the sacral regio...
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Intestinal intussusception in adult patients is a rare entity. Differently from pediatric patients, this condition is often secondary to a defined lesion. A significant percentage of these lesions are malignant. Therefore, an optimal treatment is necessary to this condition. The aim of this study is to determine causes and management of adult intus...
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OBJETIVOS: O acompanhamento ambulatorial de pacientes e a participação no exame proctológico são essenciais ao aprendizado do residente de coloproctologia. Entretanto pode haver relutância por parte dos pacientes em relação à presença do residente durante sua consulta e exame físico. Este estudo visa avaliar a visão do paciente quanto a este aspect...