Antonio Ginebreda

Antonio Ginebreda
Spanish National Research Council | CSIC · Institute of Environmental Assessment and Water Research

Professor

About

149
Publications
39,846
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Introduction
His current research interests are focused on all quality aspects of the water cycle, including the relationships between chemistry and ecology, ecotoxicology, wastewater treatment, pollutant fate and dynamics, pollutant prioritisation, environmental risk assessment and related regulatory issues

Publications

Publications (149)
Article
In this work, the Regions of Interest-Multivariate Curve Resolution (ROIMCR) method is proposed for the analysis of non-target metabolomics data. Samples from marine mussels (Mytilus galloprovincialis) exposed to a sublethal concentration (10 μg/L) of sulfamethoxazole (SMX) during 4 days in different seasonal conditions (summer and winter) were ana...
Article
A new methodology is proposed for the non-target protein analysis of samples from wastewater treatment plants (WWTP). Proteins captured using polymeric (polycaprolactonediol) probes placed along different sites of a WWTP were extracted, digested and analyzed by LC-MS/MS. Selection of the Regions of Interest (ROI) from the raw MS data allowed their...
Article
The management of the anthropogenic water cycle must ensure the preservation of the quality and quantity of water resources and their careful allocation to the different uses. Protection of water resources requires the control of pollution sources that may deteriorate them. This is a challenging task in multi-stressed catchments. This work presents...
Article
There is a worldwide growing use of chemicals by our developed, industrialized, and technological society. More than 100,000 chemical substances are thus commonly used both by industry and households. Depending on the amount produced, physical-chemical properties, and mode of use, many of them may reach the environment and, notably, the aquatic rec...
Article
Temporary rivers become dependent on wastewater effluent for base flows, which severely impacts river ecosystems through exposure to elevated levels of nutrients, dissolved organic matter, and organic micropollutants. However, biodegradation processes occurring in these rivers can be enhanced by wastewater bacteria/biofilms. Here, we evaluated the...
Preprint
Full-text available
The management of the anthropogenic water cycle must ensure the preservation of the quality and quantity of water resources and their careful allocation to the different uses. Protection of water resources requires the control of pollution sources that may deteriorate them. This is a challenging task in multi-stressed catchments. This work presents...
Article
Full-text available
Human consumption of pharmaceuticals leads to high concentrations of pharmaceuticals in wastewater, which is usually not or insufficiently collected and treated before release into freshwater ecosystems. There, pharmaceuticals may pose a threat to aquatic biota. Unfortunately, occurrence data of pharmaceuticals in freshwaters at the global scale is...
Chapter
The topic of this book is dedicated to the analysis, fate, metabolism, effects, and remediation of pharmaceutically active compounds in water-soil-biota systems. While the majority of readers are likely to already have a broad understanding of potential entry points, flows, transformation pathways, and temporary and permanent sinks of drugs in the...
Article
Wastewater discharges from cities and industries, especially megacities, and intensive livestock can be considered as main sources of pollution of our rivers and groundwater. Water pollution, therefore, constitutes a major threat to both aquatic ecosystems and human health. Here we address the influence of chemical pollution in waste- and drinking...
Article
Chemical stressors co-occur in mixtures into watercourses and this complicates predicting their effects on their ecological status. Our knowledge of river basin specific pollutants (RBSPs) is still limited, but it remains necessary to ensure the good chemical and ecological status. We performed an exercise on Mediterranean river sites exposed to ur...
Article
The capability of monitoring large molecules as possible biomarkers in wastewater will be an important contribution to the new field of sewage epidemiology. Here, we explore the use of polymer probes together with untargeted proteomics for large scale protein analysis in sewage and treated water. Polymeric probes were immersed in the influent, anox...
Article
Full-text available
To meet the United Nations (UN) sustainable development goals and the European Union (EU) strategy for a non-toxic environment, water resources and ecosystems management require cost-efficient solutions for prevailing complex contamination and multiple stressor exposures. For the protection of water resources under global change conditions, specifi...
Article
Full-text available
Current prioritisation procedures under the EU Water Framework Directive (WFD) do not account for risks from chemical mixtures. SOLUTIONS proposes a multiple-lines-of-evidence approach to tackle the problem effectively. The approach merges all available evidence from co-exposure modelling, chemical monitoring, effect-based monitoring, and ecologica...
Article
Full-text available
The concept of resilience has become popular in many disciplines far beyond its original use in the field of ecology. Despite of its wide use, it has received different definitions not always coincident. Such ambiguity is still more evident in its quantitative characterization. Most of the available methods are heavily context dependent and often d...
Article
Full-text available
In this paper, we build a preliminary inventory of dissolved phase water emissions of 36 of the 45 chemical priority substances under the European Union's Water Framework Directive. For point sources, we consider the European Pollutant Release and Transfer Register (E-PRTR) containing reported emissions from major industrial facilities. We consider...
Article
Urban wastewater inputs are a relevant pollution source to rivers, contributing a complex mixture of nutrients, organic matter and organic microcontaminants to these systems. Depending on their composition, WWTP effluents might perform either as enhancers (subsidizers) or inhibitors (stressors) of biological activities. In this study, we evaluated...
Article
Full-text available
Abstract Environmental water quality monitoring aims to provide the data required for safeguarding the environment against adverse biological effects from multiple chemical contamination arising from anthropogenic diffuse emissions and point sources. Here, we integrate the experience of the international EU-funded project SOLUTIONS to shift the foc...
Article
Full-text available
Human appropriation of water resources may induce water stress in freshwater ecosystems when ecosystem needs are not met. Intensive abstraction and regulation cause river ecosystems to shift towards non-natural flow regimes, which might have implications for their water quality, biological structure and functioning. We performed a meta-analysis of...
Article
Rivers extend in space and time under the influence of their catchment area. Our perception largely relies on discrete spatial and temporal observations carried out at certain sites located throughout the catchment (monitoring networks, MN). However, MNs are constrained by (a) the distribution of sampling sites, (b) the dynamics of the variable con...
Article
Full-text available
River ecosystems are subject to multiple stressors that affect their structure and functioning. Ecosystem structure refers to characteristics such as channel form, water quality or the composition of biological communities, whereas ecosystem functioning refers to processes such as metabolism, organic matter decomposition or secondary production. St...
Article
Full-text available
Polymers are used in high amounts in a wide range of applications from biomedicine to industry. Because of the growing awareness of the increasing amounts of plastic wastes in the aquatic environment during recent years, the evaluation of their biodegradability deserves special attention. In the past, most efforts were dedicated to studying the bio...
Article
Full-text available
We used the trait composition of macroinvertebrate communities to identify the effects of pesticides and multiple stressors associated with urban land use at different sites of four rivers in Spain. Several physical and chemical stressors (high metal pollution, nutrients, elevated temperature and flow alterations) affected the urban sites. The occu...
Article
Full-text available
Degradation of solid polymers in the aquatic environment encompasses a variety of biotic and abiotic processes giving rise to heterogeneous patterns across the surface of the material, which cannot be investigated using conventional Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) that only renders an “ave...
Article
Full-text available
Characterization of river ecosystems must take into consideration both structural and functional aspects. For the latter, a convenient and simple approach for routine monitoring is based on the decomposition of organic matter measured in terms of breakdown of natural organic substrates like leaf litter, wood sticks. Here we extended the method to a...
Article
Full-text available
We studied the relative importance of environmental factors (river flow, nutrients, dissolved organic matter) and organic micro-pollutants [herbicides, insecticides, industrial organic compounds, personal care products, antibiotics and pharmaceuticals, (PhCs)] to the structure and function of epilithic biofilms under various hydrological conditions...
Article
Full-text available
Land use type, physical and chemical stressors, and organic microcontaminants were investigated for their effects on the biological communities (biofilms and invertebrates) in several Mediterranean rivers. The diversity of invertebrates, and the scores of the first principal component of a PCA performed with the diatom communities were the best des...
Article
Diclofenac (DCF) and sulfamethoxazole (SMX) are highly consumed pharmaceuticals and concentrated in effluents from conventional wastewater treatment plants (WWTPs) since they are not completely eliminated. Under microbial mediated nitrification/denitrification processes occurring in nitrifying activated sludge DCF biotransformed into its nitroso an...
Chapter
The present chapter provides a review of the occurrence, fate, and risk associated to different families or emerging and priority organic micropollutants in the rivers of Catalonia. Compounds belonging to diverse groups such as industrial compounds, perfluoroalkyl substances, pesticides, halogenated flame retardants, pharmaceuticals and hormones, p...
Chapter
The Catalan Water Agency (ACA) established a WFD Monitoring Programme for a period of 6 years (from 2007 to 2012) in order to provide a proper water status diagnosis just before the water management plan's updating in the Catalan River Basin District (NE Spain). Most of applied monitoring tools were developed over the last decade in close cooperati...
Chapter
Most river ecosystems are under the joint effects of co-occurring stressors, and attributing the mechanisms by which multiple stressors interact and produce individual and combined effects can be highly complex. This chapter describes the structural and functional responses of the biological communities (biofilms and macroinvertebrates) to differen...
Chapter
The Catalan Water Agency (ACA) established a WFD Monitoring Programme for a period of 6 years (from 2007 to 2012) in order to provide a proper water status diagnosis just before the water management plan’s updating in the Catalan River Basin District (NE Spain). Most of applied monitoring tools were developed over the last decade in close cooperati...
Article
Full-text available
Ecotoxicological risk assessment of chemical pollution in four Iberian river basins (Llobregat, Ebro, Júcar and Guadalquivir) was performed. The data set included more than 200 emerging and priority compounds measured at 77 sampling sites along four river basins studied. The toxic units (TU) approach was used to assess the risk of individual compou...
Article
Full-text available
Starting from measured river concentrations, emission factors of 158 organic compounds out of 199 analyzed belonging to different groups of priority and emerging contaminants [pesticides (25), pharmaceuticals and hormones (81), perfluoroalkyl substances (PFASs) (18), industrial compounds (12), drugs of abuse (8) and personal care products (14)] hav...
Article
Full-text available
The determination of the real toxicity of sediments in aquatic ecosystems is challenging and necessary for an appropriate risk assessment. Different approaches have been developed and applied over the last several decades. Currently, the joint implementation of chemical, ecological and toxicological tools is recommended for an appropriate and succe...
Article
The vision of a sustainable and safe use of chemicals to protect human health, preserve the environment and main- tain the ecosystem requires innovative and more holistic approaches to risk assessment (RA) in order to better in- form decision making. Integrated risk assessment (IRA) has been proposed as a solution to current scientific, societal an...
Chapter
The present chapter provides a general perspective on the occurrence, ecotoxicological risk, and prioritization of emerging and classical contaminants in Mediterranean river basins with special focus on the Iberian Peninsula as representative case, in the light of the results recently obtained. Risk assessment and prioritization criteria based on e...
Conference Paper
Full-text available
Llobregat river has been the subject of research studies for years because of its typical Mediterranean river behavior characterized with significant ßow variations (between 1 and more than 100 m3 /s), high nutrient and large number of pollutants. The catchment is heavily populated and constitutes the main supply water source of the Barcelona metro...
Article
Full-text available
Water scarcity is a serious environmental problem in many European regions, and will likely increase in the near future as a consequence of increased abstraction and climate change. Water scarcity exacerbates the effects of multiple stressors, and thus results in decreased water quality. It impacts river ecosystems, threatens the services they prov...
Article
Full-text available
A proposed ruling by the U.S. Environmental Protection Agency (EPA), aimed at clarifying which bodies of water that flow intermittently are protected under law (1), has provoked conflict between developers and environmental advocates. Some argue that temporary streams and rivers, defined as waterways that cease to flow at some points in space and t...
Article
Full-text available
Mediterranean rivers are characterized by highly variable hydrological regimes that are strongly dependent on the seasonal rainfall. Sediment transport is closely related to the occurrence of flash-floods capable to deliver enough kinetic energy to mobilize the bed and channel sediments. Contaminants accumulated in the sediments are likely to be mo...
Article
The Llobregat is a Mediterranean river that is severely impacted by anthropogenic pressures. It is characterized by high flow variability which modulates its chemical and biological status. The present work evaluates the effects of flow changes on the concentration of pharmaceutically active compounds (PhACs) and their relationship to cellular para...
Article
Chemometric methods are applied to the analysis and interpretation of large multivariate datasets obtained in environmental monitoring studies. Concentrations of multiple organic compounds were measured in river samples taken from several sampling sites, at various geographical locations, during a number of campaigns and/or sampling time periods. S...
Conference Paper
The attenuation of pharmaceutical residues contamination in the aquatic environment depends on various complementary processes such as dilution, sorption to sediments, and degradation (i.e. photodegradation and biodegradation). One of the environmental parameters driving the attenuation of pharmaceutical contamination is therefore water flow. Water...
Conference Paper
Llobregat River basin is heavily exploited by human activities, including urban, industrial and agricultural uses that transfer into both point and diffuse pollution. The biggest contamination comes from 59 WWTPs located throughout the Llobregat river basin. This river manifests typical Mediterranean hydrological pattern, characterized by acute flo...
Article
Pesticide contamination of groundwater is of paramount importance because it is the most sensitive and the largest body of freshwater in the European Union. In this paper, an isotopic dilution method based on on-line solid phase extraction-liquid chromatography (electrospray)-tandem mass spectrometry (SPE-LC(ESI)-MS/MS) was used for the analysis of...
Article
This review examines information generated over the past decade on the pollution of rivers in regions with a mediterranean-type climate (med-climate). Pollution has clearly increased in the last 100 years and is correlated with the development of industry, agriculture and human population. Important efforts have been made in some med-climate countr...
Article
In the last decade the political awareness of river water quality issues has grown substantially over the world and legislation is accordingly adapting. In the European Union (EU), two different directives regulate separately the characteristics of the discharged water and the chemical status of the receiving freshwater ecosystem. On the one hand,...
Article
The objective of this study was to determine different brominated flame retardants (BFRs) in sewage sludge produced in 17 wastewater treatment plants (WWTPs) located in the Northeast of Spain. A total of eight polybrominated diphenyl ether (PBDE) congeners, from tri- to deca-BDEs, were analyzed. The emerging BFR compounds, hexabromobenzene (HBB), p...
Article
In the present work, a new method is proposed for the analysis of linear (lVMS) and cyclic methylsiloxanes (cVMS) in waters and sediments. The method is based on liquid-liquid extraction followed by gas chromatography coupled to tandem mass spectrometry (GC-MS/MS) using a triple quadrupole analyser (QqQ) working in selected reaction monitoring (SRM...
Article
Solid phase extraction with Poly (2,6-diphenyl-p-phenylene oxide) Polymer (Tenax) was used for determining the bioavailability of eleven pyrethroids in field collected sediments with different organic carbon content (OC). The bioavailable fraction of pyrethroids decreased with increasing OC in sediments; the percentages of desorption ranged from 10...
Article
This paper presents a new methodology to assess the risk of water effluents from waste-water treatment plants (WWTPs) based on fuzzy logic, a well-known theory to deal with uncertainty, especially in the environmental field where data are often lacking. The method has been tested using the effluent's pollution data coming from 22 waste-water treatm...
Article
The occurrence of 73 representative pharmacologically active compounds (PhACs) was assessed in a sewage-impacted section of the Llobregat River (NE Catalonia, Spain). This Mediterranean river is characterized by flow rate fluctuations strongly influenced by seasonal rainfall. River flow variations increase the potential environmental risk posed by...
Chapter
Knowledge of pollutants’ occurrence in the environment is essential in order to undertake accurate risk assessment studies. Determining the concentration of chemicals is a crucial step to quantify the levels to which both ecosystems and human population can be exposed. Traditionally, analysis has been the main way for determining concentrations in...
Article
Data from four Spanish basin management authorities were analysed. Chemical and biological data from four Spanish basin management authorities were analysed, focusing on three consecutive years. Aims were to i) determine the chemicals most likely responsible for the environmental toxicological risk in the four Spanish basins and ii) investigate the...
Article
The extensive and intensive use of chemicals in our developed, highly technological society includes more than 100,000 chemical substances. Significant scientific evidence has lead to the recognition that their improper use and release may result in undesirable and harmful side-effects on both the human and ecosystem health. To cope with them, appr...
Article
Full-text available
The Llobregat River, which is characterized by important fluctuations of the flow rates, receives treated waters from WWTPs. During the years 2007 and 2008, the Llobregat River basin suffered from a severe drought which affected the supply of drinking water facilities (DWF) that rely on the exploitation of the river water. The Catalan Water Agency...
Article
Mediterranean rivers are characterized by a high flow variability, which is strongly influenced by the seasonal rainfall. When water scarcity periods occur, water flow, and dilution capacity of the river is reduced, increasing the potential environmental risk of pollutan