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Antonio Vittorino Gaddi

Antonio Vittorino Gaddi
Italian Society of Digital Health and Telemedicine

MD, PhD

About

289
Publications
31,238
Reads
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4,696
Citations
Introduction
Infectious diseases prevention. Air Pollution. Clinical epidemiologi of chronic diseases. Genetics and Chronic diseases.
Additional affiliations
July 2020 - present
Italina Society of Telemedicine
Position
  • CEO
Description
  • www.sitelemed.it
September 2015 - June 2020
Emilia Romagna Region Society of Digital Health and TeleMedicine
Position
  • CEO
January 2009 - August 2012
University of Ferrara
Position
  • Master's Student
Description
  • Teaching (8 hours per year) as part of a master on topics related to e-health, telemedicine and research methodology
Education
January 1971 - July 1977
University of Bologna
Field of study
  • Medicine and Surgery

Publications

Publications (289)
Chapter
After almost a year in the COVID-19 era, nothing has been done to assess facial masks currently available for professionals and for the general public, to improve the efficacy of the masks or to promote their correct use.
Chapter
COVID-19 struck the world in early 2020 changing the same perception of reality as we have known it in the last decades. The onset of a novel completely unknown infection presented some challenges no one was ready to deal with. In this very complex scenario, the first step is to understand the enemy in an attempt of finding its soft spots. Then, we...
Article
Full-text available
BACKGROUND: Pasta plays an important role in human nutrition, nevertheless its organoleptic, structural and bromatologic properties have not been completely studied. OBJECTIVE: The study aims to compare the ultrastructure pasta cross-sections produced with reduced mechanic stress and low heat exposure technique (Pietro Massi Technology ™) to common...
Article
Full-text available
“Online guidelines for face mask use to prevent COVID-19 in the general public are currently inconsistent across nations and regions, and have been changing often. Efforts to create greater standardization and clarity should be explored in light of the status of COVID-19 as a global pandemic” (Laestadius Linnea et al, JMRI May 25, 2020) Non si può...
Article
Consumption of omega-3 fatty acids, including the precursor α-linolenic acid (ALA) is often sub-optimal and not in line with international guidelines. Supplementation is debatable, but some individuals, e.g., pre-diabetic, low-grade inflammation, cardiometabolic yet otherwise healthy subjects, might benefit from supra-physiological omega-3 intake,...
Article
Full-text available
Our work concerns the actual problem of spread of SARS- CoV-2 outbreak which requires fast and correct as possible answer. In current scenario, the need of rapid answer put away the imperative of proper methodology. We focus on the serogical immunoassay for diagnosis of Covid-19 as an important weapon not only for diagnostic purpose, but also for e...
Article
Full-text available
Russo La pandemia causata dal SARS-CoV-2 ha trovato impreparati i sistemi sanitari di tutto il mondo; la velocità di diffusione del virus, la sua fatalità, la sua resistenza, hanno prodotto, in soli due mesi, un radicale sconvolgimento delle abitudini e degli stili di vita di quasi tutte le popolazioni del mondo. Ai problemi correlati direttamente...
Article
Full-text available
COVID-19 is a viral disease secondary to the infection by the SARS-CoV-2 virus that can lead to a severe respiratory distress. The diagnosis of COVID-19 represents a major challenge. Currently the nasopharyngeal or throat swabs for the detection of SARS-CoV-2 RNA by Polymerase Chain Reaction (PCR) is considered the only validated method for the con...
Article
Functional food is considered to be effective in promoting health and wellbeing. Patients with Type 2 Diabetes Mellitus strongly depend on diet to achieve better glycaemic control and to reduce the burden of the disease. However, adherence to a controlled diet and to proper monitoring of the disease may be challenging for the patients and their fam...
Preprint
Full-text available
As the tide of Covid-19 flood the world, health authorities are implementing a number of measures that have deeply changed the way people live. However, there is no shared consensus on how to communicate to the public what is happening, and why these extreme interventions are needed. Instead, people received in the latest weeks contrasting messages...
Preprint
Full-text available
As Covid-19 spreads around the world, the level of uncertainty related to this infection remains high. Governments and health systems are following different and uncoordinated strategies to contain the epidemic. The use of personal protective devices aimed to protect people from air pollution may help to contain the spreading of the disease. Unfort...
Article
Full-text available
Tra confusione mediatica volontaria (fake news dolose e colpose), involontaria (spesso legata alla superficialità), insufficienze nel settore della comunicazione del rischio, eccessiva prudenza politica di alcuni esperti, incapacità decisionali ai vertici della catena di comando e dubbi reali della scienza (=assenza di conoscenze e di misure; assen...
Article
Full-text available
In year 2000 the Nobel Laureate Joshua Lederberg wrote in a famous statement: “It’s our wits versus their genes” [1]. The imbalance of powers in the fight against microbes is coming to light, as the Covid-19 infection is striking the world. Not by chance, Lederberg’s lament concluded a recent paper with the evocative title of “Escaping Pandora’s bo...
Article
Full-text available
Peripheral arterial disease is associated with very high cardiovascular risk. The main symptom is intermittent claudication, which strongly affects the quality of life. Therefore, treatment goals in peripheral arterial disease consist of the reduction of cardiovascular events and the relief of symptoms. An increase in pain-free walking distance, ev...
Article
BACKGROUND:Lipoprotein separation and analysis is critical for the classification of different atherogenic dyslipidemias. Several methods are used in clinical practice to assess lipoprotein profile. Yet, those may give different diagnostic outcomes, as no standardization scale is currently available; thus, no effective comparison is possible. Combi...
Chapter
Air pollution is a complex matter because of its inner features; because of its social, economic, political, and ethical implications; and because of the complex interactions between pollutants and the human organism. The effects of air pollution, in fact, are still largely unknown; some are, and will remain, unpredictable. The promotion of medical...
Book
This book examines in detail the clinical implications of those diseases that either are primarily triggered by air pollution or represent direct consequences of air pollutants. The aim is to provide medical practitioners with practical solutions to issues in diagnosis and treatment while simultaneously furnishing other interested parties with cruc...
Chapter
Air pollution is a global concern. The Earth has gone through a number of phases and natural selections that have marked the history of our species. Epochal changes have influenced those processes, such as major catastrophes, plagues, famines, and pandemics. Air pollution, although not new, may signal the rise of a new era, being able to modify loc...
Chapter
Air pollution can be considered a model to describe complexity and its implication in medicine. The number of components and interactions, the distribution of airborne pollutants through space and time and the possible short-and long-term effects on cells, tissues, organs and apparatus are an exhaustive example. The whole human being is more comple...
Chapter
Air pollution remains a major issue in terms of health promotion. Many are the implications and the possible strategies aimed to solve the problem. Those are mainly related to the need to prevent the exposure or effectively reduce the effects on exposed people (pre-primary, primary, secondary and tertiary prevention).
Chapter
Several researches provide compelling evidences on the cardiovascular effects of fine particulate matter (PM) for the development of atherosclerosis and cardiovascular disease and in triggering acute cardiac events. PM10, PM2.5 and PM0.3 are strongly associated with increased incidence of myocardial infarction (MI), stroke, arrhythmias and vascular...
Research Proposal
Systematic review on the effects of sulodexide on claudication in patients with peripheral vascular diseases
Chapter
To overcome problems related to air pollution, and for protection against its negative effects on health, a number of actions are required at the individual, local, national, and international levels. The role of prevention is crucial, as the effects of pollution on health are still largely unknown; some of them could show up years after exposure....
Chapter
In this chapter, we speak about the global problem of pollution, and we want to suggest the strategy that governments and citizens should adopt to oppose it. We want to explain the logic, ethical and scientific bases of air pollution prevention also inspired by that wisdom that should induce the community to use effective tools to protect themselve...
Chapter
In Italy the military research aims to introduce, as secondary, a technology transfer practice for civilian-use purposes. Specifically, the developed wireless body sensor network (WBSN), which started as a research to improve soldiers’ protection, has the potential to be beneficial also to the civilian population. Our advanced prototypical sensors...
Chapter
This chapter is about the state of the art for the creation of a good and sharable in medical record. This kind of record should take into account the inception point; that means that it has to start with the first encounter with the patient, where his or her history has to be properly taken. To achieve such a result, the record is supposed to star...
Article
Full-text available
Background: Creatine phosphate (CrP) plays a fundamental physiological role by providing chemical energy for cell viability and activity, especially in muscle tissue. Numerous pathological conditions, caused by acute or chronic ischaemic situations, are related to its deficiency. For these reasons, it has been used as a cardioprotective agent in h...
Article
Full-text available
Background. Acute gastroenteritis is a major cause of morbidity and mortality in youth age in developing and developed countries, with a bacterial origin detected in a significant percentage of cases. A meta-analysis on the use of rifaximin in children in case of gastroenteritis has been performed. Search methods. All the available publications rel...
Book
Full-text available
The debate over eHealth is alive as never before. Supporters suggest that it will result in dramatic innovations in healthcare, including a giant leap towards patient-centered care, new opportunities to improve effectiveness, and enhanced wellness and quality of life. In addition, the growing market value of investments in health IT suggests that e...
Article
The future of eHealth and telemedicine has recently become a much debated and controversial subject. It is widely believed that eHealth will play an increasingly important role in shaping healthcare systems in the twenty-first century. The rising burden of chronic diseases and the potential of eHealth for cutting costs and improving quality and saf...
Article
Education has a crucial role in the development and implementation of eHealth systems. The spread of knowledge among the different stakeholders involved in those process is crucial, provided that the correct target and the proper educational models are chosen. In a continous mutating scenario like the one of the ICT is, a traditional approach canno...
Article
To define the main features of patients treated with oral antidiabetics, evaluating monotherapy (MT), loose-dose combination therapy (LDCT) and fixed-dose combination therapy (FDCT); to describe medication adherence to the different therapies; and to evaluate the differences in compliance with the prescribed therapy regimen among prevalent and inci...
Chapter
Questa storia inizia da molto lontano. In un tempo in cui l’uomo viveva circondato da una natura indomita, e dove ogni giorno era l’inizio di una nuova lotta per la sopravvivenza. Come gli animali che lo circondavano, egli era costretto a procacciarsi il cibo ogni giorno, a rintanarsi in ripari naturali, e ad affrontare passivamente le intemperie....
Article
Full-text available
Type 2 diabetes has become a disease with a high economic and social impact. The ARNO Observatory is a clinical data warehouse consisting of a network of local health care units (ASL) scattered throughout the Italian territory which collects data on health care consumption for about 10.5 million people. The purpose of this study was to evaluate the...
Chapter
Full-text available
ICTs offer great opportunities for delivering telemedicine and social care in a number of domains including services for the elderly. This area of application, however, presents many challenges at many different levels. The purpose of this chapter is to describe an approach followed, and explore some lessons learned in Bologna (Italy). The stated o...
Article
Oxidized LDL (oxLDL) is a highly immunogenic particle that plays a key role in the development of atherosclerosis. Some data suggest a protective role of OxLDL autoantibodies (OLAB) in atherosclerosis. Our aim was to assess the effect of olive oil polyphenols on the immunogenicity of oxLDL to autoantibody generation. In a crossover, controlled tria...
Chapter
Full-text available
Il lavoro sintetizza le più recenti acquisizioni sugli effetti delle proteine vegetali, e in particolare delle proteine della soia, sul metabolismo delle lipoproteine e sulla prevenzione cardiovascolare. Viene sottolineato il ruolo determinane della ricerca sperimentale e dei trial clinici, che, negli ultimi 20 anni, hanno documentato in modo molto...
Article
Full-text available
It is widely believed that e-Health will play an increasingly important role in shaping healthcare systems in the twentyfirst century. The raising burden of chronic diseases and the potential of e-Health in improving the quality and safety of preventive health services make e-Health a great opportunity to apply to widespread preventive intervention...
Article
Full-text available
Several studies claim that psychophysical stress and depression contribute significantly to cardiovascular disease (CVD) development. The aim of our research is to discover and analyse a possible relationship between two psychosocial disorders (depression and perceived mental stress) and traditional cardiovascular risk markers. We selected 106 subj...
Article
Full-text available
A relatively large body of evidence supports the notion that glomerular capillary wall and mesangial alterations in diabetic nephropathy involve biochemical alterations of glycoproteins in these structures. Evidence in experimental animals rendered diabetic reveals that the administration of heparin and other anionic glycoproteins can effectively p...
Article
We aimed to verify the extent of a previously cited relationship between tympanosclerosis and atherosclerosis by investigating subjects with dysfunction in lipid metabolism but no clinically apparent symptoms of atherosclerotic disease. Forty hypercholesterolemic patients were submitted to Doppler ultrasound examination of carotid and vertebrobasil...
Article
Full-text available
Recent evidence suggests that at least a part of the polyunsaturated fatty acids (PUFAs) heart protective effect is mediated by a relatively small but significant decrease in blood pressure level. We retrospectively evaluated the long-term effect of a PUFA supplementation on the blood pressure level of 111 hypertriglyceridemic subjects with untreat...
Article
Full-text available
In human LDL, the bioactivity of olive oil phenols is determined by the in vivo disposition of the biological metabolites of these compounds. Here, we examined how the ingestion of 2 similar olive oils affected the content of the metabolic forms of olive oil phenols in LDL in men. The oils differed in phenol concentrations as follows: high (629 mg/...
Article
Full-text available
Novel Mutation in the Apob Gene (Apo B-15.56): A Case Report Familial hypobetalipoproteinemia (FHBL) is a rare co-dominant genetic disorder characterized by decrease of plasma low density lipoprotein-cholesterol (LDL-c) or apolipoprotein B (Apo-B) equal to or less than the 5 th percentile for the population. We describe a 48-year-old male who prese...
Article
Cardiovascular disease is a dominant cause of global death, and atherosclerosis is its pre-eminent precursor, which begins with the loss of endothelium integrity, increased permeability to atherogenic lipoproteins and other pathological phenomena which result in intima-media thickness increase. We describe the case of a 48-year-old woman affected b...
Article
Full-text available
To evaluate whether a nutritional education intervention on a general population cohort is able to balance the metabolic effects of incident menopause in a large sample of perimenopausal women. We measured body mass index (BMI), blood pressure, plasma lipids, fasting plasma glucose, and prevalence of metabolic syndrome in two groups of perimenopaus...
Article
It is not known whether serum level of vascular remodelling parameters, such as matrix metalloproteinases could be modulated by physical activity and whether the eventual change could be influenced by metabolic syndrome (MS) diagnosis. Open, intervention study to evaluate the effects of a sequential physical activity training on inflammatory, proth...
Conference Paper
Full-text available
The elderly care is characterized by integration of health and social care, is performed by several different agencies, requires a continuum of assistance and not episodic approach. These considerations has led us to overcome the traditional ICT approach done by several applications connected with property mechanism towards new solutions proposed b...
Article
The aim of our study was to test the long-term effectiveness and tolerability of a nutraceutical based approach in reducing cholesterolemia in statin intolerant subjects with and without metabolic syndrome in primary prevention for cardiovascular disease. We carried out a prospective, clinical trial enrolling 48 subjects intolerant to more than one...
Article
Recent evidences suggest that modulation of vascular structure by matrix metalloproteinases (MMPs) could be a main determinant of acute cardiovascular events in high-risk subjects. The authors consecutively selected 46 subjects affected by familial combined hyperlipidemia (FCH), 44 by metabolic syndrome (MS), 44 by FCH and MS, and 40 healthy subjec...
Article
Full-text available
To evaluate the short-term cardiometabolic effect of a sequential physical activity programme on pharmacologically untreated hypertensive overweight women and on age-matched men. We enrolled 80 overweight patients with newly diagnosed hypertension, not treated with antihypertensive nor antihyperlipidaemic drugs or under stabilized treatment. After...
Article
Full-text available
The aim of this study was to comparatively evaluate the long-term effects of psyllium husk and guar gum supplementation on metabolic syndrome (MS) components. We randomised 141 MS patients to soluble psyllium husk powder or guar gum 3.5 g t.i.d. to be taken 20 min before the main 2 meals, or to a standard diet for a cumulative period of 6 months. B...
Article
Full-text available
The aim of our study was to directly compare the metabolic effect of monounsaturated fatty acid rich oils and polyunsaturated fatty acid rich oils on the plasma lipid pattern of moderately hypercholesterolaemic subjects under controlled isocaloric condition. After a 30-day run-in diet, 44 healthy Caucasian subjects with moderate hypercholesterolaem...
Article
Objective: Several Studies claimed that Psychophysical stress can be considered as a risk factor for cardiovascular disease (CVD) development. We administered the Perceived Stress Questionnaire (PSQ) to elderly people to disclose a possible relation between stress and metabolic parameters. Methods: We selected 57 subjects over 75 years old (M:39, F...
Article
Familial Combined Hyperlipidemia (FCH) is a common metabolic disorder characterized by: a) increase in cholesterolemia and/or triglyceridemia in at least two members of the same family, b) intraindividual and intrafamilial variability of the lipid phenotype, and, c) increased risk of premature coronary heart disease (CHD). FCH is one of the most co...
Conference Paper
The aim of our study was to test the long-term effectiveness and tolerability of a nutraceutical based approach in reducing cholesterolemia in statin intolerant subjects with and without metabolic syndrome in primary prevention for cardiovascular disease. We carried out a prospective, clinical trial enrolling 48 subjects intolerant to more than one...