Antonio J. Del Águila-Carrasco

Antonio J. Del Águila-Carrasco
University of Plymouth | UoP · School of Health Professions

PhD

About

39
Publications
6,163
Reads
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405
Citations
Additional affiliations
July 2018 - present
University of Plymouth
Position
  • Lecturer
July 2017 - December 2017
University of Valencia
Position
  • PhD
September 2015 - May 2016
University of Murcia
Position
  • PhD Student

Publications

Publications (39)
Article
Full-text available
Previous research work suggests that predictable target motion such as sinusoidal movement can be anticipated by the visual system, thereby improving the accommodative response. The validity of predictable motion for studying human dynamic accommodation is sometimes put into question. The aim of this work was to assess the effect of anticipation al...
Preprint
Full-text available
Previous research work suggests that predictable target motion such as sinusoidal movement can be anticipated by the visual system, thereby improving the accommodative response. The validity of predictable motion for studying human dynamic accommodation is sometimes put into question. The aim of this work was to assess from a practical perspective...
Article
Significance: We show that the amplitude of accommodation decreases with retinal illumination even under photopic reading conditions and a constant pupil size. This result provides a basis for clinical approaches that are not based on an optical explanation. Purpose: We investigated the effect of retinal illuminance on the amplitude of accommoda...
Article
Full-text available
Modern methods of measuring the refractive state of the eye include wavefront sensors which make it possible to monitor both static and dynamic changes of the ocular wavefront while the eye observes a target positioned at different distances away from the eye. In addition to monitoring the ocular aberrations, wavefront refraction methods allow meas...
Presentation
Full-text available
Purpose: To test the hypothesis that accommodation responds to the convergence or divergence of light rays that form out-of-focus images and not simply to blur.
Article
Full-text available
Purpose: We tested the hypothesis that changes in accommodation after instillation of Phenylephrine Hydrochloride (PHCl) observed in some studies could be caused by changes in optics. Methods: We performed two experiments to test the effects of PHCl on static and on dynamic accommodation in 8 and 6 subjects, respectively. Objective wavefront mea...
Article
This manuscript aims to evaluate the tolerance to rotation of a toric monofocal and a toric bifocal intraocular lenses with different cylinder powers. Theoretical designs based on wavefront aberrations were created to simulate a toric monofocal and a toric bifocal intraocular lens. Cylinder power ranged from −1 D to −6 D, in steps of −1 D. Toleranc...
Article
Full-text available
The aim of this work was to ascertain whether there are differences in amplitude, latency, and peak velocity of accommodation and disaccommodation responses when different analysis strategies are used to compute them, such as fitting different functions to the responses or for smoothing them prior to computing the parameters. Accommodation and disa...
Article
Full-text available
The changes in the iridocorneal angle structure during accommodation are assessed by means of anterior segment optical coherence tomography. Thirteen right eyes were included in the study. The device used for the measurement was the Visante® omni system. The stimuli were set up at different vergences (0.0 D,-1.5 D, and-3.0 D). The angle opening dis...
Article
Full-text available
Eyes of children and young adults change their optical power to focus nearby objects at the retina. But does accommodation function by trial and error to minimize blur and maximize contrast as is generally accepted? Three experiments in monocular and monochromatic vision were performed under two conditions while aberrations were being corrected. In...
Article
Full-text available
Purpose: To determine if human accommodation uses the eye’s own monochromatic aberrations to track dynamic accommodative stimuli. Methods: Wavefront aberrations were measured while subjects monocularly viewed a monochromatic Maltese cross moving sinusoidally around 2D of accommodative demand with 1D amplitude at 0.2 Hz. The amplitude and phase (del...
Article
Full-text available
Purpose: The purpose of the study was to assess non-invasively the changes in the anterior chamber eye, crystalline lens morphology, and ciliary muscle during accommodation by means of an anterior chamber optical coherence tomographer (OCT), and correlate them with vergence. Methods: Twenty-five eyes of twenty-five healthy subjects, whose mean a...
Thesis
Ocular accommodation is the autofocus mechanism of the healthy young eye that allows objects at different distances to be seen clearly. Even in the absence of binocular, monocular, and chromatic cues, most eyes continue to be able to accommodate. How? The fundamental mechanism driving accommodation under these stringent conditions is still unclear....
Article
Full-text available
AIM: To investigate the potential effect that odd and even-order monochromatic aberrations may have on the accommodation response of the human eye. METHODS: Eight healthy subjects with astigmatism below 1 D, best corrected visual acuity 20/20 or better and normal findings in an ophthalmic examination were enrolled. An adaptive optics system was use...
Article
Full-text available
The aim of this study was to determine whether dynamic accommodation responds to isolated blur cues without feedback, and without changes in the distance of the object. Nine healthy subjects aged 21 to 40 years were recruited. Four different aberration patterns were used as stimuli to induce blur: (1) the eye's natural, uncorrected, optical aberrat...
Article
Purpose: To present a methodology for evaluating the optical quality of rotationally symmetrical contact lenses (CLs) from a single power profile. Methods: Simulated rotationally symmetrical power profiles corresponding to different CLs designs (monofocal, two-zone center-near bifocal, and four-zone center-distance bifocal) were used to calculat...
Article
In visual experiments that require real-time partial correction of wavefront aberrations, small errors occur that accumulate over time and lead to drifts in Zernike coefficients of the uncorrected aberrations. A simple algorithm that does not require the inclusion of an additional optical path to obtain independent measurements of the eye's aberrat...
Presentation
Full-text available
We tested the hypothesis that accommodation operates as a contrast-maximizing negative feedback system.
Thesis
Ocular accommodation is the autofocus mechanism of the healthy young eye that allows objects at different distances to be seen clearly. Even in the absence of binocular, monocular, and chromatic cues, most eyes continue to be able to accommodate. How? The fundamental mechanism driving accommodation under these stringent conditions is still unclear....
Conference Paper
El objetivo de este estudio es averiguar cómo afectan a la función visual los cambios típicos, básicamente cambios en la aberración esférica (AE), que se producen en la óptica ocular tras una cirugía para corregir la miopía o hipermetropía (cirugía refractiva). Para ello se diseñó y montó un sistema de óptica adaptativa acondicionado para las carac...
Article
Full-text available
PURPOSE. To determine whether changes in wavefront spherical curvature (optical vergence) are a directional cue for accommodation. METHODS. Nine subjects participated in this experiment. The accommodation response to a monochromatic target was measured continuously with a custom-made adaptive optics system while astigmatism and higher-order aberrat...
Article
The effects of aberrations on image quality and the objectively assessed depth of focus (DoF) were studied. Aberrometry data from 80 young subjects with a range of refractive errors was used for computing the visual Strehl ratio based on the optical transfer function (VSOTF), and then, through-focus simulations were performed in order to calculate...
Article
Full-text available
Aim: To analytically assess the effect of pupil size upon the refractive power distributions of different designs of multifocal contact lenses. Methods: Two multifocal contact lenses of center-near design and one multifocal contact lens of center-distance design were used in this study. Their power profiles were measured using the NIMO TR1504 de...
Article
Full-text available
Purpose: To assess the accommodation response after short reading periods using a tablet and a smartphone as well as determine potential differences in the accommodation response at various stimulus vergences using a Hartmann- Shack aberrometer. Methods: Eighteen healthy subjects with astigmatism of less than 1 D, corrected visual acuity of 20/20...
Article
Full-text available
Accommodation is controlled by the action of the ciliary muscle and mediated primarily by parasympathetic input through postganglionic fibers that originate from neurons in the ciliary and pterygopalatine ganglia. During accommodation the pupil constricts to increase the depth of focus of the eye and improve retinal image quality. Researchers have...
Article
We present and test a methodology for generating simultaneous vision with a deformable mirror that changed shape at 50 Hz between two vergences: 0 D (far vision) and −2.5 D (near vision). Different bifocal designs, including toric and combinations of spherical aberration, were simulated and assessed objectively. We found that typical corneal aberra...
Article
Full-text available
Purpose: To compare the optical quality between two intraocular lenses (IOLs): the Mini WELL Ready progressive multifocal (SIFI Medtech, Catania, Italy), and the TECNIS Symfony (Abbott Laboratories, Illinois, USA), which both provide a continuous range of vision from far to near positions. Methods: The in vitro optical quality of each lens was a...
Article
Purpose To present a metric for assessing the in vitro optical quality of rotationally symmetrical optical elements based on volume calculation under the surface defined by the axial modulation transfer function (MTF). Setting University of Valencia, Valencia, Spain. Design Experimental study. Methods The metric volume under the axial MTF was us...
Article
Purpose: To evaluate the optical quality of 3 multifocal intraocular lenses (IOLs): the Mini Well Ready progressive multifocal aspheric IOL, the AT LISA trifocal diffractive IOL, and the Finevision full diffractive trifocal IOL. Setting: University of Valencia, Valencia, Spain. Design: Experimental study. Methods: An instrument designed for...
Article
Purpose: To compare the optical quality under large apertures among three multifocal intraocular lenses (IOLs): the TECNIS Symfony ZXR00 (Abbott Laboratories, Abbott Park, IL), the AT LISA tri 839MP (Carl Zeiss Meditec, Jena, Germany), and the Finevision (PhysIOL, Liège, Belgium). Methods: The in vitro optical quality of each lens was assessed w...
Article
Full-text available
The purpose of this study was to describe the design and characterization of a new opto-mechanical artificial eye (OMAE) with accommodative ability. The OMAE design is based on a second-pass configuration where a small source of light is used at the artificial retina plane. A lens whose focal length can be changed electronically was used to add the...
Article
To assess whether corneal parameters and aberrations are affected by accommodation. Optics Department, University of Valencia, Valencia, Spain. Prospective cross-sectional study. The Galilei G4 dual Scheimpflug device was used to obtain data on the anterior and posterior axial curvatures, total corneal power (TCP), and corneal pachymetry from 3 cor...
Article
To assess the effect of different disposable soft contact lenses on several corneal parameters-thickness, anterior and posterior curvature, and volume-by means of a Scheimpflug imaging-based device (Pentacam HR). Diurnal variations of these parameters were taken into account. Twenty-one young, healthy subjects wore 4 different types of daily dispos...
Article
To assess the effect of seven different daily disposable contact lenses upon corneal thickness, as well as upon tear meniscus volume, by using optical coherence tomography (OCT). Thirty-four young healthy subjects wore seven different types of daily disposable soft contact lenses, each for a period of 12h: Delefilcon A, Nelfilcon A, Omafilcon A, Fi...
Article
Purpose To assess the effect of different disposable soft contact lenses upon corneal thickness, and upon anterior and posterior corneal curvatures using a dual-Scheimpflug imaging based device. Methods Twenty-eight young, healthy subjects wore four different types of daily disposable soft contact lenses on four different days: Dailies Total1, Pro...
Article
Purpose To study changes in the anterior chamber depth (ACD), anterior chamber angle, and pupil diameter with accommodation. Setting University of Valencia, Valencia, Spain. Design Evaluation of diagnostic technology. Methods A rotating Scheimpflug camera (Pentacam HR) was used to measure changes in the ACD, anterior chamber angle, and pupil dia...
Article
Full-text available
To compare the ocular anterior chamber depth, white-to-white distance, anterior chamber angle, and pupil diameter, as measured with two different Scheimpflug imaging devices. This transversal study included 80 right eyes from 80 subjects aged from 20 to 40 years. Their spherical equivalents ranged from -4.25 to +1.00 diopters (D). Each eye's anteri...

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