Antonino Vallesi

Antonino Vallesi
University of Padova | UNIPD · Department of Neuroscience

PhD
Associate Professor at University of Padova, Italy

About

152
Publications
25,948
Reads
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3,300
Citations
Introduction
Interests: executive functions, cognitive aging, interaction between space and time, neuroimaging, ERPs, hemispheric asymmetries
Additional affiliations
September 2015 - present
University of Padova
Position
  • Professor (Associate)
Description
  • Neuroimaging, Funzioni esecutive e psichiatria (8 Hours) Students: Specializzandi di Psichiatria
March 2015 - present
University of Padova
Position
  • Professor (Associate)
Description
  • Cognitive Neuroscience (undergraduate course for Tecnici di Neurofisiopatologia, 20 hrs)
February 2015 - January 2021
University of Padova
Position
  • Professor (Associate)
Description
  • Methodology for the Behavioral Sciences (at PhD level, 4-20 hrs per year)
Education
November 2003 - February 2007
September 1998 - June 2003
University of Padova
Field of study
  • Neuropsychology and Experimental Psychology

Publications

Publications (152)
Preprint
The Stroop task has been a seminal paradigm in experimental psychology, so much that, in addition to the original color-word version, a multitude of alternative variations has been proposed. The spatial Stroop task, compared to many of the other variants, might potentially be not only a more proper variation but it also might overcome some of the m...
Preprint
The spatial Stroop task measures the ability to resolve interference between relevant and irrelevant spatial information. Besides satisfying the requirements for being a proper Stroop task, its purely spatial version ensures methodological advantages over the original color-word verbal task. We recently proposed a 4-choice spatial Stroop task that...
Article
Full-text available
Alzheimer’s disease (AD) represents the most common type of neurodegenerative disorder. Although our knowledge on the causes of AD remains limited and no curative treatments are available, several interventions have been proposed in trying to improve patients’ symptomatology. Among those, transcranial magnetic stimulation (TMS) has been shown a pro...
Preprint
Full-text available
A questionnaire to collect unintended effects of Transcranial Magnetic Stimulation: A consensus based approach, Clinical Neurophysiology (2022), doi: https://doi. Abstract Transcranial magnetic stimulation (TMS) has been widely used in both clinical and research practice. However, TMS might induce unintended sensations and undesired effects as well...
Article
Objective To disentangle the physiopathology of cognitive/affective impairment in Coronavirus disease-2019 (COVID-19), we studied long-term cognitive and affective sequelae and sleep high-density electroencephalography (EEG) at 12-month follow-up in people with a previous hospital admission for acute COVID-19. Methods People discharged from an int...
Article
Full-text available
Homotopic functional connectivity reflects the degree of synchrony in spontaneous activity between homologous voxels in the two hemispheres. Previous studies have associated increased brain homotopy and decreased white matter integrity with performance decrements on different cognitive tasks across the life-span. Here, we correlated functional homo...
Article
Objective The present study investigated the impact of hearing impairment on the implementation of proactive and reactive cognitive control strategies across the ageing process. Methods 31 hearing-impaired (HI) individuals with one cochlear implant and 41 normal-hearing (NH) listeners of different ages performed the AX–CPT, a well-validated task t...
Article
Though the assessment of cognitive functions is proven to be a reliable prognostic indicator in patients with brain tumors, some of these functions, such as cognitive control, are still rarely investigated. The objective of this study was to examine proactive and reactive control functions in patients with focal brain tumors and to identify lesione...
Article
Full-text available
Executive functions (EF) are a set of higher-order cognitive abilities that enable goal-directed behavior by controlling lower-level operations. In the brain, those functions have been traditionally associated with activity in the Frontoparietal Network, but recent neuroimaging studies have challenged this view in favor of more widespread cortical...
Article
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Background: Spino-bulbar muscular atrophy is a rare genetic X-linked disease caused by testosterone insensitivity. An inverse correlation has been described between testosterone levels and empathic responses. The present study explored the profile of neural empathic responding in spino-bulbar muscular atrophy patients. Methods: Eighteen patients...
Article
Alzheimer's disease (AD) is characterized by different clinical entities. Although AD phenotypes share a common molecular substrate (i.e., amyloid beta and tau accumulation), several clinicopathological differences exist. Brain functional networks might provide a macro-scale scaffolding to explain this heterogeneity. In this review, we summarize th...
Article
“Macrographia”, a relatively rare symptom generally following cerebellar diseases, consists of an abnormally large handwriting. The case reported in the present investigation shows several outstanding features. First, it is of the progressive variety, letters increase in size as one goes through the word towards the lower-right portion of space. Mo...
Article
Full-text available
Cognitive impairment after a stroke has a direct impact on patients’ disability. In particular, impairment of Executive Functions (EFs) interferes with re-adaptation to daily life. The aim of this study was to explore whether adding a computer-based training on EFs to an ordinary rehabilitation program, regardless of the specific brain damage and c...
Article
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Electroencephalographic (EEG)‐neurofeedback training (NFT) is a promising technique that supports individuals in learning to modulate their brain activity to obtain cognitive and behavioral improvements. EEG‐NFT is gaining increasing attention for its potential “peak performance” applications on healthy individuals. However, evidence for clear cogn...
Article
Full-text available
Dementia with Lewy bodies (DLB) is a neurodegenerative disease characterized by cognitive, behavioral and motor symptoms and has a more challenging clinical management and poorer prognosis compared to other forms of dementia. The experience of lockdown leads to negative psychological outcomes for fragile people such as elderly with dementia, partic...
Article
Full-text available
Implicit learning refers to the incidental acquisition and expression of knowledge that is not accompanied by full awareness of its contents. Implicit sequence learning (ISL) represents one of the most useful paradigms to investigate these processes. In this paradigm, participants are usually instructed to respond to the location of a target that m...
Article
Facilitated processing of negative information might contribute to the etiopathogenesis and maintenance of depressive symptoms. Cardiac vagal tone, indexed by heart rate variability (HRV), is believed to represent a proxy of the functional integrity of the neural networks implicated in brooding rumination, affective interference and depression. The...
Article
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Many aspects of attention decline with aging. There is a current debate on how aging also affects sustained attention. In this study, we contribute to this debate by meta-analytically comparing performance on the go/no-go Sustained Attention to Response Task (SART) in younger and older adults. We included only studies in which the SART had a low pr...
Presentation
Full-text available
Many research programs in cognitive psychology and neuroscience have adopted a distinction between proactive control (i.e., a form of control that involves advance preparation for the current goal) and reactive control (i.e., a form of control that requires a cue for the current goal to be retrieved). For that distinction to be useful, however, it...
Article
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Resilience is the capacity of complex systems to persist in the face of external perturbations and retain their functional properties and performance. In the present study, we investigated how individual variations in brain resilience, which might influence response to stress, aging and disease, are influenced by genetics and/or the environment, wi...
Article
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Different cortical regions respond with distinct rhythmic patterns of neural oscillations to Transcranial Magnetic Stimulation (TMS). We investigated natural frequencies induced by TMS in left and right homologous dorsolateral prefrontal cortices (DLPFC) and related hemispheric differences. In 12 healthy young adults, single-pulse TMS was delivered...
Article
Full-text available
The brain predicts the timing of forthcoming events to optimize responses to them. Temporal predictions have been formalized in terms of the hazard function, which integrates prior beliefs on the likely timing of stimulus occurrence with information conveyed by the passage of time. However, how the human brain updates prior temporal beliefs is stil...
Article
Full-text available
Aging is associated with several changes in cognitive functions, as well as in motivational and affective processes, which in turn interact with cognitive functions. The present study aimed to investigate error awareness (EA), which declines with aging, in relation to motivation and anxiety. Adopting an experimental task, we firstly tested the hypo...
Article
It has been proposed that at least two distinct processes are engaged during task switching: reconfiguration of the currently relevant task-set and interference resolution arising from the competing task-set. While in healthy individuals the two are difficult to disentangle, their disruption is thought to cause different impairments in brain-damage...
Conference Paper
Sleep quality might influence the risk of developing Alzheimer’s disease (AD) in mild cognitive impairment (MCI) patients, driving alterations in brain morphology and functional connectivity. However, the relationship between sleep, gray matter atrophy, and functional connectivity is poorly understood. The present study aims to compare levels of th...
Conference Paper
Sleep has been identified as a modifiable factor involved in both the development and progression of Alzheimer’s disease (AD). Previous findings have suggested that poor sleep may be associated with increased risk of AD. Conversely, higher quality of sleep may slow progression of pathophysiological mechanisms in mild cognitive impairment (MCI) thro...
Preprint
Full-text available
Dementia with Lewy bodies (DLB) is a neurodegenerative disease characterized by cognitive, behavioral and motor symptoms and has a more challenging clinical management and poorer prognosis respect to other forms of dementia. The experience of lockdown leads to negative psychological outcomes for fragile people such as elderly with dementia, particu...
Article
Full-text available
Posterior parietal cortex is frequently activated during episodic memory retrieval but its role during retrieval and its interactions with the hippocampus are not yet clear. In this fMRI study, we investigated the neural bases of recognition memory when study repetitions and retrieval goals were manipulated. During encoding participants studied wor...
Article
Cognitive control is particularly challenged when it is necessary to resolve interference and correct our behavior on-the-fly. To do this, it is necessary to inhibit the ongoing wrong action and reprogram a new motor plan as appropriate for the current task. This ability requires a complex interaction between cognitive and motor control. Here, we a...
Article
This narrative review addresses the neural bases of two executive functions: criterion-setting – the capacity to flexibly set up and select task rules and associations between stimuli, responses and non-responses; and monitoring – the process of continuously evaluating whether task rules are being applied optimally. There is a documented tendency f...
Article
High quality of sleep may mitigate the impact of pathophysiological mechanisms in mild cognitive impairment (MCI) through functional connectivity reorganization of neural networks underlying higher cognitive functions. Thirty-eight MCI patients stratified into high and low quality of sleep according to a self-reported questionnaire for sleep habits...
Article
Task‐switching paradigms, which involve task repetitions and between‐task switches, have long been used as a benchmark of cognitive control processes. When mixed and single‐task blocks are presented, two types of costs usually occur: the switch cost , measured by contrasting performance on switch and repeat trials during the mixed‐task blocks, and...
Article
Background Different amount of cumulative exposure to the toxic mutant form of the huntingtin protein might underlie distinctive pattern of striatal connectivity in premanifest Huntington’s disease (pre‐HD). Aim of this study is to investigate disease burden‐dependent cortical‐ and subcortical‐striatal loops in different pre‐HD stages. Methods Six...
Article
Full-text available
This meta-analytical review assesses the utility of the Trail Making Test (TMT), versions A and B, in detecting migraine-related cognitive deficits. A comprehensive literature search was performed in two electronic databases and other sources to obtain relevant studies administering TMT to migraine patients. Search terms included “migraine” and “Tr...
Preprint
The brain predicts the timing of forthcoming events to optimize responses to them. Temporal predictions have been formalized in terms of the hazard function, which integrates prior beliefs on the likely timing of stimulus occurrence with information conveyed by the passage of time. However, how the human brain updates prior temporal beliefs is stil...
Article
Full-text available
The frontal aslant tract (FAT) is a recently documented white matter tract that connects the inferior and superior frontal gyri with a tendency to be more pronounced in the left hemisphere. This tract has been found to play a role in language functions, particularly verbal fluency. However, it is not entirely clear to what extent FAT asymmetry is r...
Article
Full-text available
Objectives: Mindfulness practice can enhance different aspects of attentional functions, such as the ability to sustain the attentional focus over time. However, it is still unclear whether this practice might indeed impact higher cognitive functions, such as control mechanisms that allow the appropriate and flexible allocation of attentional resou...
Article
Full-text available
Mild Cognitive Impairment (MCI) patients experience problems in financial abilities that affect everyday functioning. To date, the neural correlates of decline in this domain are unclear. This study aims at examining the correlation between the pattern of brain atrophy of MCI patients and performance on financial abilities. Forty-four MCI patients...
Preprint
Intrinsic brain dynamics may play an important role in explaining inter-individual variability in executive functions. In the present electroencephalography (EEG) study, we focused on the brain lateralization patterns predicting performance on three different monitoring tasks of temporal, verbal and spatial nature. These tasks were administered to...
Article
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Despite network studies of the human brain have brought consistent evidence of brain regions with diverse functional roles, the neuropsychological approach has mainly focused on the functional specialization of individual brain regions. Relatively few neuropsychological studies try to understand whether the severity of cognitive impairment across m...
Article
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Resting-state functional magnetic resonance imaging (rs-fMRI) has the potential to shed light on the pathophysiological mechanisms of Huntington's disease (HD), paving the way to new therapeutic interventions. A systematic literature review was conducted in three online databases according to PRISMA guidelines, using keywords for HD, functional con...
Article
An important aspect of cognitive control is the ability to overcome interference, by boosting the processing of task-relevant information while suppressing the irrelevant information. This ability is affected by the progressive cognitive decline observed in aging. The aims of this study were to shed light on the neural spectral dynamics involved in...
Article
Error processing is a critical step towards an efficient adaptation of our behavior to achieve a goal. Little research has been devoted to investigate the contribution of the dorsolateral prefrontal cortex (DLPFC) in supporting error processing. In this study, the causal relationship of the DLPFC in error commission was examined by means of a repet...
Article
Full-text available
Executive functions refer to high-level cognitive processes that, by operating on lower-level mental processes, flexibly regulate and control our thoughts and goal-directed behavior. Despite their crucial role, the study of the nature and organization of executive functions still faces inherent difficulties. Moreover, most executive function models...
Article
The brain predicts the timing of forthcoming events to optimize processes in response to them. Temporal predictions are driven by both our prior expectations on the likely timing of stimulus occurrence and the information conveyed by the passage of time. Specifically, such predictions can be described in terms of the hazard function, that is, the c...
Article
Several studies have evaluated the effect of anodal transcranial direct current stimulation (tDCS) over the prefrontal cortex (PFC) for the enhancement of working memory (WM) performance in healthy older adults. However, the mixed results obtained so far suggest the need for concurrent brain imaging, in order to more directly examine tDCS effects....
Article
Full-text available
Several studies have evaluated the effect of anodal transcranial direct current stimulation (tDCS) over the prefrontal cortex (PFC) for the enhancement of working memory (WM) performance. However, results are mixed, and the functional consequences of prefrontal tDCS during WM tasks are still unknown, especially regarding potential benefits for cogn...
Article
Full-text available
Evidence from epidemiological, laboratory and clinical research suggests a link between age-related auditory declines and domain-general cognitive declines. Nevertheless, few studies have experimentally compared measures of non-auditory cognitive functions in younger normal hearing adults (YN), older adults with typical hearing thresholds for their...
Article
Full-text available
Objective: This study considered the potential role of both protective factors (cognitive reserve, CR) and adverse ones (general slowing) in modulating cognitive flexibility in the adult life-span. Method: Ninety-eight individuals performed a task-switching (TS) paradigm in which we adopted a manipulation concerning the timing between the cue and t...
Article
Full-text available
Background: Error awareness is essential to maintain an adaptive and goal-directed behavior and is supposed to rely on the activity of the right dorsolateral prefrontal cortex (DLPFC). However, studies employing electrophysiological methods and functional resonance imaging (fMRI) do not allow to establish a causal relationship between error awarene...
Article
Full-text available
Traditionally, the left hemisphere has been thought to extract mainly verbal patterns of information, but recent evidence has shown that the left Inferior Frontal Gyrus (IFG) is active during inductive reasoning in both the verbal and spatial domains. We aimed to understand whether the left IFG supports inductive reasoning in a domain-specific or d...
Article
Full-text available
Visual search tasks have often been used to investigate how cognitive processes change with expertise. Several studies have shown visual experts' advantages in detecting objects related to their expertise. Here, we tried to extend these findings by investigating whether professional search experience could boost top-down monitoring processes involv...
Article
Full-text available
A consistent body of literature reported that Parkinson’s disease (PD) is marked by severe deficits in temporal processing. However, the exact nature of timing problems in PD patients is still elusive. In particular, what remains unclear is whether the temporal dysfunction observed in PD patients regards explicit and/or implicit timing. Explicit ti...
Article
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A longstanding debate in psychology concerns the relation between handedness and cognitive functioning. The present study aimed to contribute to this debate by comparing performance of right- and non-right-handers on verbal and spatial Stroop tasks. Previous studies have shown that non-right-handers have better inter-hemispheric interaction and gre...
Chapter
Full-text available
Air traffic controllers have to guarantee safe and efficient air traffic by predicting future flight paths based on their perception and interpretation of multiple data on the radar display. The multitasking nature of their job makes the cognitive and emotional processes required in air traffic control fundamentally different from those traditional...
Article
Full-text available
Simultaneous interpretation (SI) is a cognitively demanding process that has been associated with enhanced memory and executive functions. It is unclear, however, if the previously evidenced interpreter advantages are developed through training and/or experience with SI or rather represent inherent characteristics that allow success in the field. T...
Article
Performance on tasks involving cognitive control such as the Stroop task is often associated with left lateralized brain activations. Based on this neuro-functional evidence, we tested whether leftward structural grey matter asymmetries would also predict inter-individual differences in combatting Stroop interference. To check for the specificity o...