Antonella Canini

Antonella Canini
University of Rome Tor Vergata | UNIROMA2 · Dipartimento di Biologia

Full Professor

About

179
Publications
32,292
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
3,289
Citations

Publications

Publications (179)
Article
MicroRNAs (miRNAs) are small non-coding RNAs which modulate gene expression, promoting the degradation of target mRNAs or altering their translation. In the last decade, the role of miRNAs has been largely investigated, providing interesting evidence about the key role of these molecules in plant cell and molecular biology. Recently, our research t...
Article
Background: A reliable and science-based taxonomic determination of Papaver somniferum L. (opium poppy), the illegal species of the genus Papaver, may have practical and legal implications for law enforcement. P. somniferum is a controlled plant because of its narcotic substances, such as morphine and codeine. As poppy plants have rather similar m...
Article
Full-text available
PurposeSaffron is widely used for its medicinal and culinary properties. Its stigmas are the most expensive part comparing with the flowers that are discarded during production. For that, the objective of this work was to determine the phytocomplex of stigma and flower material (except stigma) of saffron from Algeria. Crocin, picrocrocin and safran...
Article
Full-text available
In the present research, the beekeeping products (honey, pollen, propolis) obtained from farms located in the province of Pistoia (Tuscany, Italy) were analyzed, in order to characterize them and evaluate their quality. The results showed that Pistoia apistic products possessed excellent qualitative values, suggesting a first-rate level and a long...
Article
Full-text available
Our world is facing an environmental crisis that is driving scientists to research green and smart solutions in terms of the use of renewable energy sources and low polluting technologies. In this framework, photovoltaic (PV) technology is one of the most worthy of interest. Dye-sensitized solar cells (DSSCs) are innovative PV devices known for the...
Conference Paper
Full-text available
The effects of medicinal wild edible plants in human innate immunity vs intracellular bacterial pathogen
Article
Full-text available
Increasing levels of freshwater contaminants, mainly due to anthropogenic activities, have resulted in a great deal of interest in finding new eco-friendly, cost-effective and efficient methods for remediating polluted waters. The aim of this work was to assess the feasibility of using a green microalga Desmodesmus sp., a cyanobacterium Nostoc sp....
Article
Background Beyond nutrition, fruits and vegetables can be considered as natural sources of bioactive molecules, whose beneficial effects on human health are widely recognised. To improve food quality, soilless growing systems could represent a good strategy for promoting sustainable food production chain, although nutritional and nutraceutical prop...
Article
Full-text available
For the Mediterranean region, climate models predict an acceleration of desertification processes, thus threatening agriculture. The present work aimed to investigate the effect of drought and salinity on Sulla coronaria (L.) Medik., a Mediterranean forage legume, for understanding plant defence systems activated by these stressors. In detail, we f...
Conference Paper
Full-text available
A recent preventive archaeological survey at the Fara Sabina Railway Station in Passo Corese (Rieti) conduced by the SABAP-LAZ, brought to light a necropolis pertaining to 42 tombs dated back to 1 st-3 rd century AD. This area played an outstanding economic and political role in ancient times as it was crossed by the Tiber River and the via Salaria...
Article
Full-text available
In this contribution, we investigated the role of plants in the prehistoric community of Casale del Dolce (Anagni, FR, central Italy), through microparticles recovered from dental calculus. The finding of a great amount of pollen types, even in form of compact lumps, could indicate use of natural substances, such as honeybee products and/or conifer...
Article
Full-text available
Drechslera gigantea Heald & Wolf is a worldwide-spread necrotrophic fungus closely related to the Bipolaris genus, well-known because many member species provoke severe diseases in cereal crops and studied because they produce sesterpenoid phytoxins named ophiobolins which possess interesting biological properties. The unfolded protein response (UP...
Article
In the present research, the antibacterial power of Lavandula angustifolia essential oil in environmental contexts was investigated. This plant extract, known in literature for its antibiotic effects, was vaporized in five different public areas of the Policlinico Tor Vergata Hospital and the microbial contamination was monitored by settle plate sa...
Article
Full-text available
Plant microRNAs have shown the capacity to regulate mammalian systems. The potential bioactivity of miR171vr, an isoform of the plant miR171, on human embryonic kidney 293 (HEK293) cells was investigated. Bioinformatics simulations revealed that human G protein subunit alpha 12 (GNA12) transcript could represent an excellent target for miR171vr. To...
Article
The aim of the current study is to analyze the phytochemical, antioxidant and antimicrobial activities of 34 extracts prepared from Pistacia atlantica Desf. subsp. atlantica, according to gender, organ type (roots, buds and fruits), geographical location and stage of ripening. Bud extracts exhibited the highest phenolic content (565.74 ± 9.84 mg GA...
Article
Full-text available
Human microvesicles are key mediators of cell–cell communication. Exosomes function as microRNA transporters, playing a crucial role in physiological and pathological processes. Plant microvesicles (MVs) display similar features to mammalian exosomes, and these MVs might enhance plant microRNA delivery in mammals. Considering that plant microRNAs h...
Article
Ancient dental calculus represents one of the most recent and innovative sources of archaeobotanical record. Exploring this matrix, diet, past ecology, and ethnobotanical practices of antique communities may be elucidated. In the present case-study, the tartar of an Imperial Roman man, likely a salt worker, found in the necropolis of Castel Malnome...
Article
Full-text available
Plant records reveal remarkable evidence about past environments and human cultures. Exploiting dental calculus analysis and using a combined approach of microscopy and gas chromatography mass spectrometry, our research outlines dietary ecology and phytomedicinal practices of the ancient community of Motya (Sicily, eight to sixth century BC), one o...
Article
Full-text available
Plant secondary metabolites possess chemopreventive and antineoplastic properties, but the lack of information about their exact mechanism of action in mammalian cells hinders the translation of these compounds in suitable therapies. In light of this, firstly, Origanum vulgare L. hydroalcoholic extract was chemically characterized by spectrophotome...
Article
The antitumor effect of Helichrysum species has been rarely documented in literature. Thus, in the present work, the potential antineoplastic properties of the essential oil extracted from Helichrysum italicum (Roth) G. Don flower heads by hydrodistillation were investigated. The biochemical profile of the essential oil was characterized by GC–MS a...
Article
Full-text available
The only known population of Conolophus marthae (Reptilia, Iguanidae) and a population of C. subcristatus are syntopic on Wolf Volcano (Isabela Island, Galápagos). No gene flow occurs suggesting that effective reproductive isolating mechanisms exist between these two species. Chemical signature of femoral pore secretions is important for intra-and...
Article
The present research provides the osteobiographical reconstruction of the Roman Imperial population of the rural area of Muracciola Torresina (Palestrina, Rome, Italy) through an innovative multidisciplinary approach, combining evidence from skeletal biology, biomolecules and archaeobotany. The excavation of the site, unearthed 76 individuals: 84.2...
Article
Full-text available
A multidisciplinary approach, combining stable isotope analysis from bone proteins and investigations on dental calculus using DNA analysis, light microscopy, and gas chromatography coupled with mass spectrometry, was applied to reconstruct dietary and medicinal habits of the individuals recovered in the cemetery of the Castle of Santa Severa (7th-...
Article
Full-text available
Dental calculus of a Roman woman (late first century–early second century CE), supposed to be the first historical evidence of coeliac disease (CD), was subjected to archaeobotanical investigations for reconstructing diet and phytotherapeutic practices. Light microscopy provided the proof she came in contact with gluten-rich cereals (i.e. Triticeae...
Article
Full-text available
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Article
Full-text available
Background: The analysis of ancient calcified dental plaque is a powerful archaeobotanical method to elucidate the key role of the plants in human history. Methods: In this research, by applying both optic microscopy and gas chromatography mass spectrometry on this matrix, a detailed qualitative investigation for reconstructing the lifestyle of...
Article
Full-text available
MicroRNAs, a class of small, non-coding RNAs, play important roles in plant growth, development and stress response by negatively regulating gene expression. Moringa oleifera Lam. plant has many medical and nutritional uses; however, little attention has been dedicated to its potential for the bio production of active compounds. In this study, 431...
Article
Antimicrobial activity of hydroalcoholic extracts (30/70) from leaves and stems of three halophytes (Tamarix africana, Arthrocnemum macrostachyum and Suaeda fruticose) was investigated. In vivo toxicological study and anti-inflammatory activity of leaf extract of T. africana were tested on carrageenan-induced inflammatory paw edema. T. africana pos...
Article
Full-text available
There is a growing interest in therapeutically targeting the inflammatory response that underlies age-related chronic diseases including obesity and type 2 diabetes. Through integrative small RNA sequencing, we show the presence of conserved plant miR159a and miR156c in dried nuts having high complementarity with the mammalian TNF receptor superfam...
Article
Moringa oleifeira has recently been subjected to numerous scientific studies pursuing its biological properties. However, biotechnological approaches promoting the synthesis of pharmacological compounds in this species are still scarce, despite the fact that moringa metabolites have shown significant nutraceutical effects. For this reason, in vitro...
Article
The genetic characterisation of beech woods in Lazio was performed by microsatellite approach. The phylogeographic relationship existing among stands was investigated, allowing us to identify a putative glacial refugium for this species. This work provides information for management policies and conservation strategies of F. sylvatica germplasm res...
Article
Full-text available
Moringa oleifera Lam. (MO) is one of the most well-known and widely distributed species of the Moringaceae family in African communities, and various preparations of M. oleifera are used for the treatment of several diseases. Due to the extensive worldwide use of MO products, and the use of MO aqueous extract in traditional African medicine, the ai...
Article
Full-text available
Anabasis articulata is a plant widely used in popular medicine to treat several pathologies in Algerian Sahara, such as diabetes. It is also associated with two other plants to cure certain types of cancer. Few research studies have been conducted on phytochemical analysis and in vivo biological activities of this species. However, no report is ava...
Article
Full-text available
Antibacterial activity is the most investigated biological property of honey. The goal of this study was to evaluate the antibacterial activity of 57 Slovak blossom honeys against Staphylococcus aureus and Pseudomonas aeruginosa and investigate the role of several bioactive substances in antibacterial action of honeys. Inhibitory and bactericidal a...
Article
Olive quick decline syndrome (OQDS) is a dangerous plant disease, caused by the bacterium Xylella fastidiosa, which targets olive (Olea europaea). Since field observations suggested that some olive cultivars (i.e. Leccino) were more resistant to OQDS than others (i.e. Cellina di Nardò), the plant defense strategies adopted by olive to contrast X. f...
Article
Full-text available
Grapevine (Vitis vinifera L.) is one of the oldest and most important fruit crops in the world. Iran is considered as one of the regions where grapevine plants have been used and taken into cultivation. In the present study, 12 simple sequence repeat (SSR) markers were used to evaluate the genetic diversity among Iranian grape cultivars and their r...
Article
No information exists on phototrophs growing on the stone surfaces of the Catacombs of SS. Marcellino and Pietro (the site was only recently opened to the public in 2014). Therefore, it was decided to characterise the microbial communities and to compare them with those of the other previously studied catacombs. Moreover, a new non-invasive strateg...
Article
Full-text available
In nature, many plants or their extracted compounds have been found to possess anti-inflammatory features and therapeutic properties against infectious as well as non-infectious diseases, including cancer. In this study, we analysed the immunomodulatory effects on innate immune cells of hydroalcoholic extract from Origanum vulgare L. ssp. hirtum (H...
Data
O. vulgare extract does not exert any direct toxic effects on host cells. DC (A, B), M1 (C, D) and M2 (E, F) (2x105/well) were stimulated with HyE-Ov at different concentration (1, 3, 9 and 27 mg/ml of equivalent plant material) for 3 days. Cells and supernatants were subjected to MTT Assay (A, C, E) and to CytoTox 96 Assay (B, D, F). Data are expr...
Data
Hydroalcoholic extract of O. vulgare (HyE-Ov) does not exert any direct toxic effects on mycobacteria. BCG-lux was cultured in 7H9 medium in the presence or absence of the extract and the mycobacterial growth was monitored for 2 weeks by a luminometric assay. Data are expressed as Replication Index, calculated as the ratio between the Relative Lumi...
Data
Assessment of direct mycobactericidal effect of HyE-Ov. BCG-lux was stored at -80°C and, after thawing, centrifuged and suspended in Middlebrook 7H9 (Difco) broth supplemented with 10% ADC (albumin, dextrose and catalase), 0.05% Tween 80 and 50 μg/ml Hygromycin B (Invitrogen). Bacteria were sonicated, in a bath sonicator, for 3 min to remove mycoba...
Data
Host cell viability after infection with BCG-lux at MOI 5 and MOI 10. DC (A), M1 (B) and M2 (C) (2x105/well) were infected with BCG-lux (MOI 5 and 10) for 3 hours, were incubated for 3 days at 37°C with 5% CO2 and were subjected to MTT assay. Data are expressed as means ± SD of % of cell viability of triplicate cultures and are representative of 2...
Data
MTT assay. In order to evaluate the cell viability after infection, all cell types were infected with BCG-lux (MOI 5 and 10) for 3 hours. Washings were performed to block infection and to remove eventual extracellular bacteria, and cells were incubated for 3 days at 37°C with 5% CO2. MTT assay (Molecular Probe) was performed according to the manufa...
Data
Cytotoxicity assays. In order to analyse the possible cytotoxic effect of HyE-Ov on dendritic cells (DC), type-1 macrophages (M1) and type-2 macrophages (M2), all cell types were stimulated with HyE-Ov at different concentrations (1, 3, 9 and 27 mg/ml of equivalent plant material). After 3 days of stimulations, cell viability was assessed by MTT as...
Article
Full-text available
Wild cherry (Prunus avium L.) is a plant widely distributed around the world that possesses a great economic value. Indeed, it represents both a fruit source and one of the most important European hardwood species. For this reason, in order to obtain information about Turkish authoctonous P. avium germplasm and favor wood management policies and pr...
Article
Extracts and fractions using six solvents of increasing polarities from Northwest Algeria (Tamarix africana, Arthrocnemum macrostachyum and Suaeda fruticosa) were studied for phytochemical analysis and in vitro antioxidant properties. Methanol and water fractions were found to be the more suitable solvents used for extraction of polyphenolic compou...
Article
This study is focused on the surface engineering of detonation nanodiamonds (DND) for the delivering of therapeutic agents, and on the developing of strategies for the DND conjugation with biologically active substances. Oxidized and differently amino-functionalized DND have been investigated to identify their chemical and structural features. A se...
Article
Full-text available
This research presents an in-depth study of the skeletal remains collected from the archaeological site of Allumiere (15th-16th centuries CE; Rome, Italy). A multidisciplinary approach was used, combining skeletal biology, molecular anthropology and archaeobotany with the aim of reconstructing the osteobiography of the alum miners buried at the sit...
Data
Primer sequences used to amplify animal different DNA regions, size of the PCR product obtained and annealing temperature. (DOCX)
Data
Results of the post-cranial indices. (nr: not recordable). (DOCX)
Data
Results of the analysis on degenerative disease pattern (nr: not recordable). (DOCX)
Data
List of the skeletal remains analyzed in the present research housed at the Department of Biology of the University of Rome “Tor Vergata”. (DOCX)
Data
Presence of pathology/stress markers for each individual. Neoplasia (NP), Infectious diseases (periostitis, PO; osteomyelitis, OM; infections, IN), trauma and stress markers (fractures, FR; grasping GR), degenerative pathologies (degenerative diseases, DG; and axial degereative diseases (Schmörl’s nodes, SN)) and congenital disorders (CO), and infl...
Data
The molecules identified in dental calculus by GC-MS analysis were listed and clustered in biochemical classes for each sample. (DOCX)
Article
Full-text available
Functional foods include compounds with nutritional and health properties. The human diet could play a stronger role in cancer prevention. Only a few studies have described the presence of plant small RNA, in humans who were fed with plant foods, which demonstrated the ability of these molecules to modulate consumer’s genes and evidenced the existe...
Article
The community of Colonna (Rome, Central Italy), dated back to 8th–10th century CE, was characterized by a poor quality of life. In the present archaeobotanical investigation, we obtained a detailed qualitative reconstruction of the food habits of this Medieval population. To do it, light microscopy and GC–MS techniques were applied on the dental ca...
Article
Honeybees directly transfer plant compounds from nectar into honey. Each plant species possesses a specific metabolic profile, the amount and the typology of plant molecules that may be detected in honey vary according to their botanical origin. Aim of the present work was the spectrophotometrical determination of concentration ranges of simple phe...
Article
Thermal liquefying of crystallised honey is the most convenient option for beekeepers to fully liquefy honey. A controlled mild thermal treatment is widely used for effective and safe liquefying of crystallised honey. In this study, we demonstrated that thermal liquefying at different temperatures of 45, 55 and 65 °C does not affect the overall hon...
Article
The integration of different conversion technologies can strongly contribute to the biomass potential exploitation. To this aim, the use of intermediate pyrolysis biochar is analyzed in this paper as an alternative co-substrate in anaerobic digestion. The specie Ampelodesmos mauritanicus has been specifically chosen in this case for its capacity to...
Article
For the first time, plant pigments were detected in Roman frescoes. Indeed, only sporadic papers proved the application of natural hues in ancient paintings and none of them relative to Roman art. Therefore, eight differently coloured fragments of Julio-Claudian wall paintings, collected from Terme degli Stucchi Dipinti archaeological site (Rome, I...
Article
Background: Ultraviolet light exposure generates, in human tissues, radical species, which represent the main cause of photo-aging, DNA damage and skin cancer onset. On the other hand, Mediterranean plants, being continuously subjected to high solar radiation levels, are naturally adapted to take on this type of abiotic stress, thanks to the produ...
Article
Full-text available
A collection of starch granules synthesized in 40 food plants was assembled. After extraction and purification, samples were subjected to optic and scanning electron microscopy investigations. Detailed images and descriptions of the starch granules are provided, evidencing all their morphological and structural features. In particular, shape, size,...
Article
The present research utilizes archaeology and physical anthropology to reconstruct the demography, occupational stress markers and health conditions of individuals that lived during the medieval era in Santa Severa (Rome, Italy). The cemetery recovered during the restoration of the Castle of Santa Severa dates back to 1232 ± 40 BP (680–890 cal.)–10...
Article
Background: Robinia pseudoacacia L. nectar and its derivative monofloral honey were systematically compared in this study, to understand how much the starting solution reflected the final product, after re-elaboration by Apis mellifera ligustica Spinola. Results: Subjected to dehydration in the hive, nectar changed its water and sugar content wh...
Article
Full-text available
Honey bees and their products are optimal bio-indicators of environmental contamination. In this study, 12 honey and beeswax samples from 6 hives located in 6 different provinces of Burkina Faso, sited near agricultural crops, were analysed. The honey yield periods taken into account were 2: the main honey yield, occurring during the dry season, an...