About
28
Publications
776
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
476
Citations
Introduction
Publications
Publications (28)
Inbred rat strains BDIX and BDIV are constitutionally susceptible and resistant, respectively, to the development of malignant peripheral nerve sheath tumors (MPNST) induced by neonatal exposure to N-ethyl-N-nitrosourea (EtNU). They represent a model system for analysis of molecular and cellular processes underlying differential cancer susceptibili...
Necrotizing fasciitis is a life threatening soft-tissue infection with a high morbidity and mortality. Prompt treatment based on extensive surgical debridement and antibiotic therapies are the therapeutic principles.
The medical records of patients with necrotizing fasciitis (n = 26) from 1996 to 2005 were retrospectively analyzed.
The localization...
Abdominal complications following open-heart surgery remain serious events as the mortality is reported to be tremendously high. The clinical presentation, the diagnostic strategy and the therapeutic management varies. We reviewed all records of those patients who developed abdominal complications with surgical consequences during the last five yea...
Introduction:
Abdominal complications following open-heart surgery remain serious events as the mortality is reported to be tremendously high. The clinical presentation, the diagnostic strategy and the therapeutic management varies. We reviewed all records of those patients who developed abdominal complications with surgical consequences during th...
Malignant fibrous histiocytoma (MFH) is a soft-tissue sarcoma created from fibroblast cells and characterized by a high rate of metastasis or recurrence with poor prognosis. We report a case of initially well differentiated (G1) MFH of the trunk in a 33-year-old woman. Two years after primary diagnosis, metastases were found in the lung, trunk, glu...
Simultaneous cardiothoracic and general surgical interventions are still a matter of controversy. We investigated the question whether combined open heart surgery or thoracic surgery and interventions of the parathyreoid respectively thyroid gland may be helpful for the patients.
The records of six patients (age range: 29-78 years) undergoing simul...
Zur Behandlung von Fremdkörperinfektionen, die in den meisten Fällen zur Entfernung des Implantates führen, reichen systemisch verabfolgte Antibiotika nicht aus. Die Therapieerfolge mit lokal applizierbaren Antibiotikaträgern (Kollagen, Polymethylmetacrylatketten) lassen hoffen, dass eine injizierbare Substanz, die Antibiotika in verzögerter Weise...
Aquaporin 1 (AQP-1) channels have been claimed to be responsible for osmotically driven free-water movement across the peritoneal membrane. Data about AQP-1 expression and its location in the human peritoneum related to clinical findings concerning ultrafiltration (UF) and free-water transport are still lacking.
Fifty-seven peritoneal biopsy specim...
Pheochromocytoma is a rare entity. When it presents during pregnancy, rapid recognition and diagnosis are crucial in order to avoid the maternal and fetal morbidity and mortality associated with severe, uncontrolled hypertension. Difficulties arise from the differential diagnosis of pre-eclampsia. We report two patients operated on for pheochromocy...
Hepatocellular carcinoma (HCC) ranks eighth among malignant tumors worldwide. Western countries belong to areas of low HCC prevalence, but incidence of HCC is rising. The aim of the present, retrospective study was to determine changes in the incidence rates and risk factors for HCC in Germany based on the data of a single center.
Epidemiological d...
Zielsetzung: Die Diagnostik des Rektumkarzinom-Rezidivs ist problematisch. Tumor-Rezidive und Narbengewebe sind hierbei die wesentlichsten Differenzialdiagnosen. Daher ist eine möglichst exakte Sicherung des Lokal-Tumor-Rezidivs und der Ausschluss anderer Tumormanifestationen entscheidend für die weitere OP-Indikation und Planung. Die Positronen-Em...
Ziel: Die Diagnostik des Rektumkarzinom-Rezidivs ist sehr problematisch. Tumor-Rezidive und Narbengewebe sind hierbei die wesentlichsten Differentialdiagnosen. Daher ist eine möglichst exakte Sicherung des Lokal-Tumor-Rezidivs und der Ausschluss anderer Tumormanifestationen entscheidend für die weitere Op-Indikation und Planung. Es werden die eigen...
A case of congenital, bilateral, diaphragmatic hernia in a patient with multiple trauma after a motor accident is presented. No anamnestic information was available because of the need for intubation at the accident site. After the insertion of bilateral chest tubes because of left sided pneumothorax and right sided haematopneumothorax a mediastina...
Postoperative peritonitis carries a higher risk of complications and mortality than does community-acquired disease. Little,
however, is known about the specific microbiology of this condition. To gain insight into this problem, the microbiological
findings of 67 patients with postoperative peritonitis were compared with those of 68 patients with c...
A case of congenital, bilateral, diaphragmatic hernia in a patient with multiple trauma after a motor accident is presented. No anamnestic information was available because of the need for intubation at the accident site. After the insertion of bilateral chest tubes because of left sided pneumothorax and right sided haematopneumothorax a mediastina...
This is the report of a patient, that had without using any assisted reproduction technology (ART) the rare event of a heterotopic pregnancy. After verifying the intrauterine pregnancy by ultrasound, the ectopic tubal pregnancy (EP) was detected at an emergency abdominal surgery as the cause of an intraabdominal hemorrhage. After removal the furthe...
Peritoneal sclerosis is a histopathologic finding that is probably causative of long-term system failure in peritoneal dialysis (PD). It may be due to uremic toxicity and the influence of peritoneal dialysate components. We intended to clarify to which degree peritoneal fibrosis and vascular changes were associated with the modalities of PD and the...
The increasing number of enterococcal infections in hospitals and reports about the development of resistance of these bacteria make it necessary to review their importance as co-pathogens in secondary peritonitis.
A prospective randomized controlled trial on primary therapy of secondary peritonitis was carried out in six centers comparing cephalos...
Sarcomas are rare malignant tumors with a large variety of histologic subtypes. The surgical approach depends more on the histologic grade, the size and the site of the tumor. Radiologic diagnosis relies predominantly on MR-imaging. Discernible improvements have taken place in soft tissue sarcoma patient survivorship and quality of life over the pa...
In surgery, computer support is still of minor importance. It is the aim of this publication to outline the concept of a computer-assisted documentation system for surgical procedures, to describe the realization of the concept and to discuss the results of the evaluation. Planning of the system started in 1988 with an analysis of existing computer...
In surgery, computer support is still of minor importance. It is the aim of this publication to outline the concept of a computer-assisted documentation system for surgical procedures, to describe the realization of the concept and to discuss the results of the evaluation. Planning of the system started in 1988 with an analysis of existing computer...
A computer system for on-line documentation of operative findings has been developed based on commercial software (MEDOS). The system has been in routine clinical use since January 1991, and up to now 5684 operations have been documented. Prospective evaluation revealed that in 76% the system is directly used by the doctors immediately after surger...
