Annie J Sasco

Annie J Sasco
University of Bordeaux · Epidemiology for Cancer Prevention

MD, MPH, MS, DrPH HDR

About

286
Publications
29,263
Reads
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7,339
Citations
Additional affiliations
September 2005 - present
Université Victor Segalen Bordeaux 2
Position
  • Inserm Director of Research
July 1983 - August 2005
International Agency for Research on Cancer
Position
  • Unit chief

Publications

Publications (286)
Article
Full-text available
Introduction: Extrapulmonary tuberculosis (EPTB) is difficult to confirm bacteriologically and requires specific diagnostic capacities. Diagnosis can be especially challenging in under-resourced settings. We studied diagnostic modalities and clinical outcomes of EPTB compared to pulmonary tuberculosis (PTB) among HIV-positive adults in antiretrovi...
Article
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Hepatocellular carcinoma (HCC) is a leading cause of cancer in West Africa where HBV infection is endemic. However, limited information is available on other risk factors such as alcohol use, HCV and HIV infection. A case‐control study was conducted in referral hospitals of Abidjan (Cote d'Ivoire), Bamako (Mali) and Lome (Togo). Cases were matched...
Article
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Exposure to chemicals from different sources in everyday life is widespread; one such source is the wide range of products listed under the title “cosmetics”, including the different types of popular and widely-advertised sunscreens. Women are encouraged through advertising to buy into the myth of everlasting youth, and one of the most alarming con...
Article
Avanços na medicina veterinária resultaram em benefícios significativos na vida de animais de estimação nos últimos 20 anos, e o aumento da expectativa de vida para animais levou a uma maior prevalência de neoplasias em cães. A Epidemiologia do Câncer e as ferramentas de análise espacial, embora bem desenvolvidas na pesquisa oncológica humana, estã...
Article
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Quickly changing technologies and intensive uses of radiofrequency electromagnetic field (RF-EMF)‑emitting phones pose a challenge to public health. Mobile phone users and uses and exposures to other wireless transmitting devices (WTDs) have increased in the past few years. We consider that CERENAT, a French national study, provides an important ad...
Article
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The Report “Variation in cancer risk among tissues can be explained by the number of stem cell divisions” (C. Tomasetti and B. Vogelstein, 2 January, p. 78), is dangerously misleading because it understates the role of prevention in cancer causation. It is widely acknowledged that many cancers
Article
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Tacit knowledge in environmental health (EH) responds to the strong need to relate environmental conditions with health effects and implement the ideas produced in the educational framework. Training programs on EH have to educate professionals in dealing with problems where environmental degradation threatens health and to answer the currently inc...
Article
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Setting: Drug resistance threatens tuberculosis (TB) control, particularly among human immunodeficiency virus (HIV) infected persons. Objective: To describe practices in the prevention and management of drug-resistant TB under antiretroviral therapy (ART) programs in lower-income countries. Design: We used online questionnaires to collect prog...
Article
: Cancers associated with immunosuppression and infections have long been recognized as a major complication of HIV/AIDS. More recently, persons living with HIV are increasingly diagnosed with a wider spectrum of HIV-associated malignancies (HIVAM) as they live longer on combination antiretroviral therapy. This has spurred research to characterize...
Article
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We describe the association between age at antiretroviral therapy (ART) initiation and 24-month CD4 cell response in West African HIV-infected children. All HIV-infected children from the IeDEA paediatric West African cohort, initiating ART, with at least two CD4 cell count measurements, including one at ART initiation (baseline) were included. CD4...
Article
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In Martinique, prostate cancer incidence rates have been increasing since the 1980s and are actually among the highest worldwide. Exposure to lifestyle (changes in dietary habits), environmental factors (exposure to organochlorine pesticides) and modifications in diagnostic and screening procedures, are favored etiological hypotheses. The aim of th...
Article
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Cervical cancer is the most common cancer among women and the leading cause of cancer deaths in women in Cote d'Ivoire. Low resource countries can now prevent this cancer by using HPV vaccine and effective and affordable screening tests. However the implementation of these prevention strategies needs well-trained human resources. Part of the soluti...
Article
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Facing the dual burden of invasive cervical cancer and HIV in sub-Saharan Africa, the identification of preventable determinants of Cervical Intraepithelial Neoplasia (CIN) in HIV-infected women is of paramount importance. A cervical cancer screening based on visual inspection methods was proposed to HIV-infected women in care in Abidjan, Côte d'Iv...
Article
Community awareness is crucial to early detection of breast cancer in low-and-middle-income countries. In Ghana 60% of the cases are detected at late stages. Breast Care International (BCI) is a Ghanaian non-governmental organization dedicated to raising breast cancer awareness. A cross-sectional survey was designed to assess the impact of BCI prog...
Article
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Background: In developing countries, 6% of deaths are due to cancer but cancer prevention is not practiced. Humans can prevent themselves from a number of workplace and environmental carcinogens. Objectives: To assess exposure to carcinogens, risky behaviours and associated preventive methods. Methods: A structured questionnaire was used to co...
Article
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Several studies have shown an increase in PCB sources in Africa due to leakage and wrongly disposed transformers, continuing import of e-waste from countries of the North, shipwreck, and biomass burning. Techniques used in the recycling of waste such as melting and open burning to recover precious metals make PCBs contained in waste and other semiv...
Article
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vii " The future we want " , the main document summarizing the action areas advocated by the Rio+20 conference (Rio de Janeiro, Brazil, June 20-22 nd), advocates " green economy " as a main instrument to eradicate poverty, while maintaining the healthy functioning of the environment. " Green economy " is a reply to global capitalism and the excesse...
Article
Mammographic density (MD) is a strong marker of breast cancer risk, but it is debated whether the association holds, and is of a similar magnitude, for different subtypes of breast cancer defined by receptor status or gene expression profiles. A literature search conducted in June 2012 was used to identify all studies that had investigated the asso...
Article
Mammographic density (MD) is a strong marker of breast cancer risk, but it is debated whether the association holds, and is of a similar magnitude, for different subtypes of breast cancer defined by receptor status or gene expression profiles. A literature search conducted in June 2012 was used to identify all studies that had investigated the asso...
Article
Full-text available
Background Cancer is a growing co-morbidity among HIV-infected patients worldwide. With the scale-up of antiretroviral therapy (ART) in developing countries, cancer will contribute more and more to the HIV/AIDS disease burden. Our objective was to estimate the association between HIV infection and selected types of cancers among patients hospitaliz...
Conference Paper
This study evaluates incidence time trends of malignant brain tumors by primary sites and histological subtypes in the US. SEER*Stat was used to obtain age, sex, year, and histologic-specific incidence rate in SEER 9 Registry between 1975 and 2008. Primary sites and histologic subtypes of malignant brain tumors were identified based on ICD-O-3 co...
Data
Morphological types of lymphomas (N = 119) according to HIV status, the IeDEA West Africa collaboration, 2009–2011. *Morphological subtypes according the international classification of disease in oncology third edition (ICD-O3). Abbreviations: NHL: Non-Hodgkin Lymphoma, NOS None Otherwise Specified. (DOCX)
Data
The International epidemiological Database to Evaluate AIDS (IeDEA) collaboration in West Africa. *Member of the IeDEA West Africa Technical Committee. (DOCX)
Article
El cáncer del ovario representa alrededor del 4% de los cánceres femeninos y es responsable de más del 5% de los fallecimientos por cáncer. Las mujeres de raza blanca o que viven en los países desarrollados son las más expuestas. Los índices de incidencia y de mortalidad, estables entre 1980 y 2000, tienden a disminuir gracias al empleo de la antic...
Article
Contexte Une augmentation récente du cancer dans les pays du Sud est constatée. L’objectif de cette étude était de décrire les connaissances, attitudes et pratiques (CAP) des professionnels de santé non médecins, sur le cancer du sein dans différentes structures de soins de Niamey, Niger. Méthode Une enquête transversale a été réalisée dans dix ce...
Article
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We sought to document the association of Human immunodeficiency Virus (HIV) infection and immunodeficiency with oncogenic Human Papillomavirus (HPV) infection in women with no cervical neoplastic lesions identified through a cervical cancer screening programme in Côte d'Ivoire. A consecutive sample of women stratified on their HIV status and attend...
Article
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The aim of this study was to determine the pattern of histologically-proven gastric cancer in Eastern Libya and explore its association with Helicobacter pylori infection. The registries of the Departments of Histopathology, Faculty of Medicine, Benghazi University and Oncology, Al-Jomhoria Hospital, Benghazi, were reviewed for cases with primary g...
Article
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Cervical cancer screening is not yet standard of care of women attending HIV care clinics in Africa and presents operational challenges that need to be addressed. A cervical cancer screening program based on visual inspection methods was conducted in clinics providing antiretroviral treatment (ART) in Abidjan, Côte d'Ivoire. An itinerant team of mi...
Article
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The eruption of Kaposi sarcoma (KS) and aggressive non-Hodgkin lymphoma (NHL) in young homosexual men in 1981 in the West heralded the onset of the human immunodeficiency virus (HIV) infection epidemic, which remains one of the biggest challenges to global public health and science ever. Because KS and NHL were increased >10,000 and 50-600 times, r...
Data
questionnaire for the study of factors that influence general practitioners in the referral of elderly cancer patients. The final version comprises four sections and two clinical case vignettes. Section A concerns the GP's elderly patients overall (GP's perception of the age at which a person is "elderly", percentage of elderly people among patient...
Article
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A number of studies have identified advanced age as a barrier to accessing specialised oncological care. Many factors can influence the care provided for elderly patients after a diagnosis of cancer has been established or is suspected. Only one European study has analysed the decision processes leading general practitioners (GPs) to refer elderly...
Chapter
Cancer in Down syndrome (DS) is characterized by a well known and marked excess of leukemia, whereas few studies are available on solid tumours in this population. In this chapter we study the cancer mortality of DS in California. Study group: 16,808 DS cases (contributing 129,076 person-years) among 210,155 persons having received evaluations appr...
Chapter
Exposure to lifestyle, occupational, and environmental risk factors for cancer are undoubtedly different in cerebral palsy (CP) than in the general population, and these differences and others may result in a specific pattern of cancer mortality in CP. In this chapter our objective was to study the cancer mortality of CP in California. Study group:...
Chapter
The frequency of testicular cancer in men with intellectual disabilities is not known precisely, except for some genetic conditions such as Down syndrome, where it is increased. In this chapter, we have conducted a systematic review of the literature using PubMed, with a particular focus on epidemiological studies of testicular cancer in persons wi...
Article
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In the setting of recurrent events, research studies commonly count only the first occurrence of an outcome in a subject. However this approach does not correctly reflect the natural history of the disease. The objective is to jointly identify prognostic factors associated with locoregional recurrences (LRR), contralateral breast cancer, distant me...
Article
To investigate the association between alcohol use and adherence to highly active antiretroviral treatment (HAART) among human immunodeficiency virus (HIV)-infected patients in sub-Saharan Africa. Cross-sectional survey conducted in eight adult HIV treatment centres from Benin, Côte d'Ivoire and Mali. Participants and measurements During a 4-week p...
Article
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Tobacco smoking is responsible for a vast array of diseases, particularly chronic bronchitis and lung cancer. It is still unclear which constituent(s) of the smoke is responsible for its toxicity. The authors decided to focus on carbon dioxide, since its level of concentration in mainstream cigarette smoke is about 200 times higher than in the atmo...
Article
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This study evaluates the relation of the early oestrogen-regulated gene gabarapl1 to cellular growth and its prognostic significance in breast adenocarcinoma. First, the relation between GABARAPL1 expression and MCF-7 growth rate was analysed. Thereafter, by performing macroarray and reverse transcriptase quantitative-polymerase chain reaction (RT-...
Article
This study aimed at investigating whether a differential estrogen receptor beta (ER-beta) expression between the colonic subsites could correspond to a modification in proliferation, apoptosis, and adhesion of the normal colonocytes. ER-beta, Ki-67, Bcl-2, and E-cadherin expressions were investigated immunohistochemically, in normal epithelium biop...
Article
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Background: With the lengthening of life expectancy among HIV-positive subjects related to the use of highly active antiretroviral treatments, an increased risk of cancer has been described in industrialized countries. The question is to determine what occurs now and will happen in the future in the low income countries and particularly in sub-Sah...
Article
Carbon dioxide (CO2) is naturally present in the atmosphere where its concentration is about 0.038%. It is also a normal constituent of the body arising from cellular respiration or taking part in several metabolic reactions. CO2 is also one of the main side-products of combustion, and in particular of cigarette smoking. Analysis of primary tobacco...
Article
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Background: Tobacco smoking is common in human immunodeficiency virus (HIV) infected patients from industrialised countries. In West Africa, few data concerning tobacco consumption exist. Methods: A cross-sectional survey of the International Epidemiological Database to Evaluate AIDS (IeDEA) network in West Africa was conducted. Health workers a...
Article
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Human immunodeficiency virus (HIV)-infected patients are at higher risk of malignancies. In addition to traditional determinants, a specific deleterious effect of HIV and immunodeficiency is speculated. We aimed at studying the association between immunological and virological characteristics of HIV-infected patients in care and the risk of acquire...
Article
Prostate cancer is the fifth cause of cancer death in the world today. In spite of numerous studies on the subject, its aetiology has not yet been clearly defined. Three French "départements", the French Antilles (Guadeloupe and Martinique) and French Guyana present unique epidemiological, geographical, ethnic and environmental characteristics whic...
Article
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Cancer prevention, screening and early detection can provide some of the greatest public health benefits for cancer control. In low resource settings, where cancer control is challenged by limited human, financial and technical resources, cancer prevention and screening are of utmost importance and can provide significant impacts on the cancer burd...
Article
Animals kept as pets may be considered sentinels for environmental factors to which humans could be exposed. Olfactory and respiratory epithelia are directly subjected to airborne factors, which could cause DNA lesions, and the alkaline comet assay is considered a reliable tool for the assessment of DNA damage. The objective of this work is to eval...
Article
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It was the aim of this study to evaluate the risk of dying from bladder and kidney cancer in persons with Down syndrome (DS), as compared with the general population. Using data of the French national mortality statistics (INSERM) during a 21-year period, 1979-1999, we compared the observed number of deaths from renal and bladder cancer in DS subje...
Article
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The aim of this study was to assess whether one of the most common poisons of cellular respiration, i.e., carbon dioxide, is proinflammatory. CO(2) is naturally present in the atmosphere at the level of 0.038% and involved in numerous cellular biochemical reactions. We analyzed in vitro the inflammation response induced by exposure to CO(2) for 48...
Article
Cannabis is the most widely consumed illicit drug worldwide and the relation between cannabis smoking and lung cancer is suggestive, albeit inconclusive. We conducted three hospital based case-control studies in Tunisia, Morocco, and Algeria, three areas of high prevalence of cannabis consumption as well as production. This paper presents the poole...
Article
Cancer in Down syndrome (DS) is characterized by a well known and marked excess of leukemia, whereas few studies are available on solid tumors in this population. Objective: To study the cancer mortality of DS in California. Study group: 16,808 DS cases (contributing 129,076 person-years) among 210,155 persons having received evaluations approximat...
Article
Science and the information world have long been separated. The XXI century will be the one of constant interaction due to the development of novel, exceedingly efficient and fast technologies to share information, including coming from science. Whereas traditionally scientists did not interact with communication people, this is doomed to change. T...