Anne Petzold

Anne Petzold
University of Cologne | UOC · Institute of Systems Physiology

PhD Life Sciences

About

10
Publications
993
Reads
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138
Citations
Additional affiliations
July 2013 - September 2017
Imperial College London
Position
  • PhD Student
April 2013 - September 2013
University of Oxford
Position
  • Research Assistant
Description
  • investigated neural systems that drive sleep-wake transitions, manuscript in prep.
November 2012 - April 2013
University of Oxford
Position
  • Visiting Scientist
Description
  • investigated neural systems that drive sleep-wake transitions
Education
September 2013 - September 2017
Independent Researcher
Independent Researcher
Field of study
  • Neuroscience
October 2009 - March 2012
Otto-von-Guericke University Magdeburg
Field of study
  • Neuroscience
October 2006 - September 2009
Otto-von-Guericke University Magdeburg
Field of study
  • Philosophy of Mind

Publications

Publications (10)
Chapter
Physiological states such as hunger or thirst, as well as reproductive states, shape reward-seeking behavior. To understand the state-dependent neural regulation of behavior, we need to relate the activity of individual, neurochemically defined neurons to the spontaneous, unrestricted innate behavior of an animal during and across different states....
Preprint
The selective loss of cerebellar Purkinje cells is a hallmark of various neurodegenerative movement disorders, yet the precise mechanism driving their degeneration remains enigmatic. Here we show that the endocytic adaptor protein complex 2 (AP-2) is essential for the survival of Purkinje cells. Employing a multidisciplinary approach encompassing m...
Preprint
Full-text available
Sleep is under control of two processes, circadian and homeostatic regulation, but little is known about how these two processes integrate. Here, we identify a Drosophila gene, ninna nanna, encoding two alternatively spliced isoforms: Ninna and Nanna. Both proteins encode aldo-keto reductases and are expressed in different, yet interconnected neuro...
Article
Animals continuously weigh hunger and thirst against competing needs, such as social contact and mating, according to state and opportunity. Yet neuronal mechanisms of sensing and ranking nutritional needs remain poorly understood. Here, combining calcium imaging in freely behaving mice, optogenetics, and chemogenetics, we show that two neuronal po...
Article
Full-text available
Cholinergic neurons of the pedunculopontine nucleus (PPN) are most active during the waking state. Their activation is deemed to cause a switch in the global brain activity from sleep to wakefulness, while their sustained discharge may contribute to upholding the waking state and enhancing arousal. Similarly, non-cholinergic PPN neurons are respons...
Conference Paper
Full-text available
Cniderians are considered to be the first organisms to develop a Nervous System (Watanabe 2009, Anderson 2004) that qualifies for a Central Nervous System (CNS, Mackie 2004). In Cubomedusae, the CNS processes the main part of visual input and concordant output (Garm et al. 2007b). Behavior of T. cystophora is visually guided by four sets of morpholog...
Conference Paper
A series of studies point to a prominent role of brain-derived neurotrophic factor (BDNF) in long-term neural plasticity (LTP), especially in hippocampus and amygdala. BDNF impacts on behavioral tasks that rely on these brain structures, such as Morris Water Maze (MWM) and Fear Conditioning. BDNF and its receptor, TrkB, reach highest levels in hip...

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