Anne Collin

• French National Institute for Agriculture, Food, and Environment (INRAE)

1. In chicken production, a delay occurs between hatching and placement in the rearing building. This work analysed the effects of this experience on growth, metabolism, and caecal microbiota and tested whether a nutritional supplement (SUP) could mitigate these effects.2. Chicks were placed directly in a rearing room (Control: C) or were exposed t...

Dans le cadre du projet européen PPILOW (2019-2024, https://www.ppilow.eu/), l’application PIGLOW, qui bénéficie d’un développement pour téléphones portables, a été mise en place. Elle permet de réaliser des évaluations du bien-être animal (BEA), dans les élevages pour les femelles gestantes, les femelles allaitantes et leurs porcelets, les porcele...

Chicken meat production in organic systems involves free-range access where animals can express foraging and locomotor behaviours. These behaviours may promote outdoor feed intake, but at the same time energy expenditure when exploring the outdoor area. More generally, the relationship of range use with metabolism, welfare including health, growth...

La France est actuellement au premier rang des productions européennes de poulets biologiques. Cette production ne représente toutefois encore que quelques pourcents de la production nationale. L’élevage avicole biologique est souvent considéré comme respectueux du bien-être animal et de l’environnement. Cependant, au-delà de ces images positives q...

La gestion intégrée de la santé animale peut être définie comme l’ensemble des connaissances et pratiques mobilisées par l’Homme de manière coordonnée afin de favoriser la construction, préserver ou retrouver la santé des individus ou du troupeau au sein du système d’élevage. Elle se fonde sur la mobilisation conjointe de trois principes complément...

Background Nutrient availability during early stages of development (embryogenesis and the first week post-hatch) can have long-term effects on physiological functions and bird metabolism. The embryo develops in a closed structure and depends entirely on the nutrients and energy available in the egg. The aim of this study was to describe the ontoge...

La viande de volaille et les œufs sont des sources principales de protéines animales pour l'alimentation humaine dans le monde. Leur production a augmenté rapidement au cours des dernières décennies. Cependant, les productions avicoles sont vulnérables au changement climatique, en particulier au réchauffement de la planète et à ses conséquences dir...

Background Ethno-veterinary practices could be used as a sustainable developmental tool by integrating traditional phytotherapy and husbandry. Phytotherapeutics are available and used worldwide. However, evidence of their antiparasitic efficacy is currently very limited. Parasitic diseases have a considerable effect on pig production, causing econo...

L'épigénétique est communément définie comme l’étude de l'ensemble des mécanismes moléculaires impliqués dans la régulation de l’expression des gènes qui sont réversibles et transmissibles au cours du développement et parfois entre générations, sans altérer la séquence de l'ADN. Plusieurs mécanismes épigénétiques sont maintenant bien connus, comme...

Purpose The purpose of this study is to provide information on how citizens in nine countries across Europe perceive egg product quality and the importance of a product's sustainability attributes (animal welfare, country of origin and production method) in egg purchases. Design/methodology/approach The data were gathered in 2021 via an online sur...

Background In the current context of global warming, thermal manipulation of avian embryos has received increasing attention as a strategy to promote heat tolerance in avian species by simply increasing the egg incubation temperature. However, because of their likely epigenetic origin, thermal manipulation effects may last more than one generation...

Poultry production is an important agricultural sector for human food worldwide. Chicks after hatch often face health problems leading to economic losses that are deleterious for breeders. Avian defensin 2 (AvBD2) is a prominent host defense peptide of the intestinal mucosa of cecum and is involved in the resistance of poultry to bacterial pathogen...

Chicken meat production in organic systems involves free-range access where animals can express foraging and locomotor behaviours. These behaviours may promote outdoor feed intake, but at the same time induce a loss of energy in exploring. More generally, the relationship of range use with metabolism, welfare, health, growth performance and meat qu...

To improve the early perinatal conditions of broiler chicks, alternative hatching systems have been developed. On-farm hatching (OFH) with an enriched microbial and stimulating environment by the presence of an adult hen is a promising solution. Day-old certified JA 757 chicks were allotted within different hatching and rearing conditions: OFH, con...

In the current context of global warming, thermal manipulation of avian embryos has received increasing attention as a strategy to promote heat tolerance in avian species by simply increasing the egg incubation temperature. However, because of their likely epigenetic origin, thermal manipulation effects may last more than one generation with conseq...

Free-range systems provide an outdoor range for broilers to give them the possibility to express a higher frequency and a wider range of behaviours, such as exploration, compared with those raised indoors. Greater variability in outdoor range use between individuals of the same flock is often reported. Individual variation in range use may result f...

La gestion intégrée de la santé animale peut être définie comme l’ensemble des connaissances et pratiques mobilisées par l’homme de manière coordonnée afin de favoriser la construction, préserver ou retrouver la santé des individus ou du troupeau au sein du système d'élevage. Elle a pour finalité d’optimiser la santé animale et le cycle de producti...

Background Embryonic and fetal development is very susceptible to the availability of nutrients that can interfere with the setting of epigenomes, thus modifying the main metabolic pathways and impacting the health and phenotypes of the future individual. We have previously reported that a 38% reduction of the methyl donor methionine in the diet of...

In free-range and organic production systems, hens can make choices according to their needs and desires, which is in accordance with welfare definitions. Nonetheless, health and behavioral problems are also encountered in these systems. The aim of this article was to identify welfare challenges observed in these production systems in the EU and th...

Background In mammals, the nutritional status experienced during embryonic development shapes key metabolic pathways and influences the health and phenotype of the future individual, a phenomenon known as nutritional programming. In farmed birds as well, the quantity and quality of feed offered to the dam can impact the phenotype of the offspring....

The process of oxidative stress occurs all over the production chain of animals and food products. This review summarises insights obtained in different farm species (pigs, ruminants, poultry, and fishes) to underpin the most critical periods for the venue of oxidative stress, namely birth/hatching and weaning/start-feeding phase. Common responses...

This study was designed to improve the hatching performance, chick robustness and poultry health in the event of long-term egg storage and suboptimal age of the reproductive flock. A total of 9,600 eggs from one young breeder flock (28 weeks of age, batch B) and 9,600 eggs from an older breeder flock (59 weeks of age, batch E) were used (ROSS 308)....

Recent research on free-range chickens shows that individual behavioral differences may link to range use. However, most of these studies explored individual behavioral differences only at one time point or during a short time window, assessed differences when animals were out of their social group and home environment (barn and range), and in spec...

Early development is a critical period during which environmental influences can have a significant impact on the health, welfare, robustness and performance of livestock. In oviparous vertebrates, such as birds, embryonic development takes place entirely in the egg. This allows the effects of environmental cues to be studied directly on the develo...

The potential of herbal extracts containing bioactive compounds to strengthen immunity could contribute to reducing antimicrobial use in poultry. This study aimed at developing a reliable and robust methodological pipeline to assess the ability of herbal extracts to strengthen chicken innate defenses, especially concerning inflammation and oxidativ...

Background The thermal-manipulation (TM) during egg incubation is a cyclic exposure to hot or cold temperatures during embryogenesis that is associated to long-lasting effects on growth performance, physiology, metabolism and temperature tolerance in birds. An increase of the incubation temperature of Japanese quail eggs affected the embryonic and...

Chicks subjected to early stressful factors could develop long-lasting effects on their performances, welfare and health. Free access to essential oils (EO) in poultry farming could mitigate these effects and potentially reduce use of antimicrobial drugs. This study on chicken analyzed long-lasting effects of post-hatch adverse conditions (Delayed...

Background The production of foie gras involves different metabolic pathways in the liver of overfed ducks such as lipid synthesis and carbohydrates catabolism, but the establishment of these pathways has not yet been described with precision during embryogenesis. The early environment can have short- and long-term impacts on the physiology of many...

In poultry breeding, epigenetics is not a common used element in the selection of parents to breed the next generations. That is surprising as epigenetics can influence gene function, is inherited via mitosis and / or meiosis and can occur both from the female and male lines. Epigenetics have been shown to affect gene-expression and can thereby pla...

Background: The production of foie gras involves different metabolic pathways in the liver of overfed ducks such as lipid synthesis and carbohydrates catabolism, but the establishment of these pathways has not yet been described with precision during embryogenesis. The early environment can have short- and long-term impacts on the physiology of man...

Background: The production of foie gras involves different metabolic pathways in the liver of overfed ducks such as lipid synthesis and carbohydrates catabolism, but the establishment of these pathways has not yet been described with precision during embryogenesis. The early environment can have short- and long-term impacts on the physiology of man...

Background: The production of foie gras involves different metabolic pathways in the liver of overfed ducks such as lipid synthesis and carbohydrates catabolism, but the establishment of these pathways has not yet been described with precision during embryogenesis. The early environment can have short- and long-term impacts on the physiology of man...

Cold stimulations during egg incubation were reported to limit the occurrence of ascites in broilers subjected to cold temperature after 14 d of age. However, data are lacking on the impacts of such strategy in case of cold temperature conditions at start. This study aimed to evaluate the effects of incubation and posthatch cold challenge on perfor...

Background: Production conditions of layer chicken can vary in terms of temperature or diet energy content compared to the controlled environment where pure-bred selection is undertaken. The aim of this study was to better understand the long-term effects of a 15%-energy depleted diet on egg-production, energy homeostasis and metabolism via a mult...

Poultry meat and eggs are major sources of nutrients in the human diet. The long production career of laying hens expose them to biotic or abiotic stressors, lowering their production. Understanding the mechanisms of adaptation to stress is crucial for selecting robust animals and meeting the needs of a growing human population. In this study, fina...

Background: Because the cost of cereals is unstable and represents a large part of production charges for meat-type chicken, there is an urge to formulate alternative diets from more cost-effective feedstuff. We have recently shown that meat-type chicken source is prone to adapt to dietary starch substitution with fat and fiber. The aim of this st...

Glucose transport into cells is the first limiting step for the regulation of glucose homeostasis. In mammals, it is mediated by a family of facilitative glucose transporters (GLUTs) (encoded by SLC2A* genes), with a constitutive role (GLUT1), or insulin-sensitive transporters (GLUT4, GLUT8 and GLUT12). Compared to mammals, the chicken shows high l...

The processing ability and sensory quality of chicken breast meat are highly related to its ultimate pH (pHu), which is mainly determined by the amount of glycogen in the muscle at death. To unravel the molecular mechanisms underlying glycogen and meat pHu variations and to identify predictive biomarkers of these traits, a transcriptome profiling a...

Over the years, farmed birds have been selected on various performance traits mainly through genetic selection. However, many studies have shown that genetics may not be the sole contributor to phenotypic plasticity. Gene expression programs can be influenced by environmentally induced epigenetic changes that may alter the phenotypes of the develop...

Stressed animals have an increased risk of health and welfare problems, thus methods for easy and early stress detection are important for appropriate animal management. Using the ability of rats to distinguish between faeces odours from stressed and non-stressed conspecifics, we investigated whether rats could detect stress status in another speci...

Thermal manipulation during embryogenesis was previously reported to decrease the occurrence of ascites and to potentially improve cold tolerance of broilers. The objective of our study was to explore the effects of the interaction of cold incubation temperatures and cool ambient temperatures until 21 d of age on performance and body temperature. R...

Background: Genomic loci associated with histone marks are typically analyzed by immunoprecipitation of the chromatin followed by quantitative-PCR (ChIP-qPCR) or high throughput sequencing (ChIP-seq). Chromatin can be either cross-linked (X-ChIP) or used in the native state (N-ChIP). Cross-linking of DNA and proteins helps stabilizing their intera...

Decades of genetic selection have generated 2 different, highly specialized types of chickens in which 1 type, known as the layer-type chicken, expresses high laying performance while the other type, known as the broiler-type chicken, is dedicated to the production of fast-growing birds. Selected lines for the latter type often express disorders in...

The processing ability and sensory quality of chicken breast meat are highly related to its ultimate pH (pHu), which is mainly determined by the amount of glycogen in the muscle at death. To unravel the molecular mechanisms underlying glycogen and meat pHu variations and to identify predictive biomarkers of these traits, a transcriptome profiling a...

Phenotype variability depends on genetics and environmental factors. Improving farm animal performances relies on genetic variability, but the possible improvement of selection schemes taking into account nongenetic transgenerational inheritance has become a topic of choice. Indeed, the parental diet may influence the adult phenotype of the offspri...

Background Meat type chickens have limited capacities to cope with high environmental temperatures, this sometimes leading to mortality on farms and subsequent economic losses. A strategy to alleviate this problem is to enhance adaptive capacities to face heat exposure using thermal manipulation (TM) during embryogenesis. This strategy was shown to...

Variations in muscle glycogen storage are highly correlated with variations in meat ultimate pH (pHu), a key factor for poultry meat quality. Two chicken lines were divergently selected on breast pHu to understand the biological basis for variations in meat quality, i.e. the pHu- and the pHu+ lines that are characterized by a 17% difference in musc...

Cyclically cold incubation temperatures were shown to improve the resistance of broiler chickens to ascites, yet the underlying mechanisms are not known. 900 eggs obtained from 48 wk Ross broiler breeders were assigned to the following incubation treatments: Control I eggs were incubated at 37.6°C, while Cold I eggs experienced reduced incubation t...

Methionine is a rate-limiting amino-acid for protein synthesis but non-proteinogenic roles on lipid metabolism and oxidative stress have been demonstrated. Contrary to rodents where a dietary methionine deficiency led to a lower adiposity, an increased lipid accretion rate has been reported in growing pigs fed a methionine deficient diet. This stud...

Il existe chez les animaux et l'Homme une mémoire de l'environnement embryonnaire (nutrition, stress, polluants...) qui peut influencer le métabolisme des individus à l'âge adulte. Cette mémoire de l’environnement précoce est expliquée en partie par des variations de l’état épigénétique des gènes, transmises au cours des divisions cellulaires au co...

The increasing use of unconventional feedstuffs in chicken’s diets results in the substitution of starch by lipids as the main dietary energy source. To evaluate the responses of genetically fat or lean chickens to these diets, males of two experimental lines divergently selected for abdominal fat content were fed isocaloric, isonitrogenous diets w...

The increasing use of unconventional feedstuffs exhibiting high fibre content in broiler's diets results in thesubstitution of starch by lipids as the main energy source. To evaluate the adaptability of genetically fat or leanbroilers to such diets, 48 male chickens were fed isoenergetic and isoproteic diets with high (8%, HL) or low(2%, LL) lipid...

Embryo heat acclimation: which mechanisms are modified in the finishing broilers. Heat exposure affects the physiology, performance and welfare in broiler chickens. Thermal manipulations (TM) of eggs during incubation consists in increasing cyclically the temperature of incubators to 39.5°C and 65% RH from day 7 to 16 of embryogenesis. These TM imp...

More and more studies show that epigenetic information affects the phenotypes of individuals. Little is knownabout the epigenetic mechanisms in birds, although, as in many animal and plant species, these mechanisms maybe involved in trait variability. Little is known about epigenetic mechanisms in birds with the exception of thephenomenon of dosage...

The increasing use of unconventional feedstuffs in broiler's diets results in the substitution of starch by lipids as the mainenergy source. To evaluate the responses of genetically fat or lean broilers to such diets, male chickens were fed during 6weeks isoenergetic and isoproteic diets with high lipid (8 %), high fiber content (HL) or low lipid (...

Climate change is one of the major issues of our era. Many direct (high temperature) and indirect (availabilityof feed resources, sanitary challenges) consequences are expected in the short and medium term on livestock,both in the South (Mediterranean and tropical areas) where climate constraints are already important and willworsen in the near fut...

Poultry production has increased during recent decades under hot climate where extreme temperatures are predicted to occur more frequently as in Europe. To limit the negative effects of temperature variations on performance and welfare, an innovative strategy is embryo acclimation to heat or cold. The long-term effects of changes in chicken egg inc...

Methionine (Met) is the second or third limiting amino acid (AA) for growth in pigs. A dietary Met deficiency reduces proteindeposition but its impact on other animal characteristics and metabolisms remains to be clarified. This study aimed to determinethe effects of a dietary Met deficiency on lipid metabolism and antioxidant activities. From 42 d...

Excessive deposition of body fat is detrimental to production efficiency. The aim of this study was to provide plasma indicators of chickens' ability to store fat. From 3 to 9 wk of age, chickens from 2 experimental lines exhibiting a 2.5-fold difference in abdominal fat content and fed experimental diets with contrasted feed energy sources were co...

Pour optimiser la composition corporelle et la qualité des viandes tout en garantissant l’efficacité des systèmes de production, il faut comprendre et maîtriser les mécanismes régulant l'utilisation métabolique des nutriments. Dans cette synthèse, nous présentons les généralités concernant la régulation nutritionnelle du métabolisme. Quelques exemp...

Fast-growing chickens have a limited ability to tolerate high temperatures. Thermal manipulation during embryogenesis (TM) has previously been shown to lower chicken body temperature (Tb) at hatching and to improve thermotolerance until market age, possibly resulting from changes in metabolic regulation. The aim of this study was to evaluate the lo...

Little is known about epigenetic mechanisms in birds, except the phenomenon of dosage compensation of sex chromosomes, although such mechanisms could be involved in the phenotypic variability of birds, as in several livestock species. This paper reviews the literature on epigenetic mechanisms that could contribute significantly to trait variability...

Abstract Text: Little is known about epigenetic mechanisms in birds, except the phenomenon of dosage compensation of sex chromosomes, although such mechanisms could be involved in the phenotypic variability of birds, as in several livestock species. This paper reviews the literature on epigenetic mechanisms that could contribute significantly to...

Selection programs have enabled broiler chickens to gain muscle mass without similar enlargement of the cardiovascular and respiratory systems that are essential for thermoregulatory efficiency. Meat-type chickens cope with high ambient temperature by reducing feed intake and growth during chronic and moderate heat exposure. In case of acute heat e...

Cyclically cold incubation temperatures have been suggested as a means to improve resistance of broiler chickens to ascites; however, the underlying mechanisms are not known. Nine hundred eggs obtained from 48 wk Ross broiler breeders were randomly assigned to 2 incubation treatments: control I eggs were incubated at 37.6°C throughout, whereas for...

To optimize body composition and meat quality while ensuring the efficiency of production systems, it is necessary to understand and control the mechanisms regulating the metabolic utilization of nutrients. In this review, we present an overview on the nutritional regulation of metabolism. Selected and representative examples (i.e. protein and amin...

il s'agit d'un type de produit dont les métadonnées ne correspondent pas aux métadonnées attendues dans les autres types de produit : REPORT

Pour améliorer la résistance et le bien-être des poulets en croissance à la chaleur sans affecter leurs performances, il est possible de les acclimater au chaud pendant l’incubation des oeufs. Ce traitement d’acclimatation (A) correspond à une incubation des oeufs à 39,5°C pendant 12 heures par jour (E7 à E16), la température d’incubation des oeufs...

Little is known about epigenetic mechanisms in birds with the exception of the phenomenon of dosage compensation of sex chromosomes, although such mechanisms could be involved in the phenotypic variability of birds, as in several livestock species. This paper reviews the literature on epigenetic mechanisms that could contribute significantly to tra...