Anna Spinek

• PhD
• Hirszfeld Institute of Immunology and Experimental Therapy

The study aimed to determine the width of the neonatal line (NNL) and time of occurrence of accentuated lines (ALs) in enamel of deciduous incisors to assess the biological condition during pre, peri- and early postnatal development of individuals from the cemetery. For 32 incisors (16 i¹, 7 i², 9 i2) thin sections for microscopy analyses were perf...

This review aims to evaluate the accuracy of various mandibular radiomorphometric indices in comparison with DEXA BMD measurements in the diagnosis of osteopenia and osteoporosis based on a meta-analysis of the sensitivity and specificity of the indices. PRISMA statement was followed. The materials for analysis were collected in August 2023 by sear...

Background The appearance of Slavs in East-Central Europe has been the subject of an over 200-year debate driven by two conflicting hypotheses. The first assumes that Slavs came to the territory of contemporary Poland no earlier than the sixth century CE; the second postulates that they already inhabited this region in the Iron Age (IA). Testing ei...

The aim of the present exploratory study was to assess the changes in urinary oxytocin (OT) concentration during the period between five days before, and on the day of match, among rugby and handball players. Nine male rugby players with a mean age of 27.62 years (SD = 4.21) and 18 male handball players with a mean age of 17.03 years (SD = 0.57) pa...

Variations in the cross-sectional properties of long bones are used to reconstruct the activity of human groups and differences in their respective habitual behaviors. Knowledge of what factors influence bone structure in Homo sapiens and Neandertals is still insufficient thus, this study investigated which biological and environmental variables in...

This case study describes and provides a differential diagnosis for a femoral lesion. Individual M81 was a young adult male from Milicz, a 12-13th century cemetery assemblage, a subsection of the osteological collection curated by the Polish Academy of Sciences in Wrocław, Poland. The skeleton underwent standard anthropological analysis to estimate...

This paper presents the archaeological skeletal remains of four adult females presenting with cranial lesions typical of malignant neoplastic disease. The four cases were sourced from three medieval Polish skeletal assemblages: Milicz (12–13th century), Pawłów Trzebnicki (15–16th century), and Gródek nad Bugiem (13–15th century). The observed patho...

Purpose: Osteoporosis is the most widespread systemic disease of the skeleton. According to estimated data for Poland, it affects ca. 3 million people. Although the disease is multifactorial, with significant influence of environmental factors on the increase of the risk of its occurrence, genetic factors play an important role in its pathogenesis....

Objective We aim to identify maternal genetic affinities between the Middle to Final Neolithic (3850–2300 BC) populations from present-day Poland and possible genetic influences from the Pontic steppe. Materials and methods We conducted ancient DNA studies from populations associated with Złota, Globular Amphora, Funnel Beaker, and Corded Ware cul...

Objectives The aim of the present study was to assess the changes in urinary oxytocin concentration during the period between five days before, and on the day of match, among rugby and handball players. Methods The study used a repeated measures design with the relative oxytocin level as the outcome variable measured at two subsequent points of ti...

The osteoma, among other forms of benign neoplastic disease, has received little palaeopathological or palaeoepidemiological interest largely because of its asymptomatic nature. This is problematic because these tumours are regarded as common occurrences in bioarchaeological contexts, despite there being scant data to support these claims. This inv...

[This corrects the article DOI: 10.1371/journal.pone.0194966.].

Congenital synostoses are defined as rare abnormal formations of primary anatomical structures. There are three major classifications: 1) skeletal anomalies, 2) soft tissue anomalies, and 3) anomalies involving both skeletal and soft tissues. Radioulnar synostosis is the most common form of upper limb abnormality. Synostoses between the humerus and...

Congenital synostoses are defined as a rare abnormal formation of primary anatomical structures. There are three major classifications 1) skeletal anomalies, 2) soft tissue anomalies, and 3) anomalies involving both skeletal and soft tissues. A review of the clinical literature illustrates that radioulnar synostosis is the most common form of upper...

The relation of LCT-13910 genotypes and bone mineral density (BMD) has been the subject of modern-day human population studies, giving inconsistent results. In the present study we analyze for the first time a relation of LCT-13910 genotypes and BMD in historical skeletal individuals. Ancient population might be a model for testing this association...

Preservation of human skeletons used in the study. (DOCX)

Paleopathological studies suggest different patterns of age-related bone loss and osteoporosis in past populations compared with those of modern times. However, the observed interpopulational differences are often difficult to interpret due to considerable environmental and biological heterogeneity between populations from which the analyzed skelet...

Fluctuating asymmetry (FA) of paired body structures is considered to be a reliable measurement of developmental instability of humans. The aim of the study is to examine whether the mother's traumatic experience during pregnancy results in an increase of the level of fluctuating asymmetry of the structures of the face. Average relative FA of six c...