Anna Maria Nikodem

• Ph.D
• Wrocław University of Science and Technology

Objective: This in vitro study evaluated the effectiveness of three laser systems—diode, CO2, and Er:YAG—for debonding composite attachments used in aligner orthodontic therapy. Materials and Methods: Fifty extracted human premolars with composite attachments were divided into five groups (n = 10): control, RT (rotary tools), diode laser (980 nm, i...

Lightweight metals are increasingly used in biomedical engineering, and can be found in orthopaedics (screws, implants), stomatology, cardiology (stents) and as scaffolds. Magnesium alloys have a low density (1.74 g/cm³), which is very close to that of bone (1.75 g/cm³), as well as high biocompatibility, and are biodegradable. Unfortunately, their...

Zirconia crowns are employed in pediatric dentistry for the complete restoration of anterior and posterior deciduous teeth. They are considered the best option due to their esthetic appeal, high strength, biocompatibility, and resistance to wear and corrosion. This study aims to evaluate the physico-chemical, cytological, and microbial properties o...

A novel bi-layered scaffold, obtained via 3D printing and electrospinning, was designed to improve osteochondral region reconstruction. The upper electrospun membrane will act as a barrier against unwanted tissue infiltration, while the lower 3D-printed layer will provide a porous structure for tissue ingrowth. Graphene was integrated into the scaf...

Background/Objectives: Materials with an apatite structure were investigated in vitro in dental bone augmentation procedures. This scientific study aimed to compare nanosized hydroxyapatite (nHAp) and fluorapatite (nFAp) materials in the form of tablets in in vitro studies, including cytotoxicity assessment and fluoride release. Methods: The nHAp a...

In this research, poly(glycerol adipate) prepolymer (pPGA) was synthetized using enzymatic polymerization of divinyl adipate (DVA) and glycerol in reaction carried out in the presence of Candida Antarctica enzyme. The pPGA was then solved in 1,4-dioxane and mixed with L-lysine diisocyanate (LDI), bioglass, pourged into mold with sodium chloride, cu...

Purpose Caries or iatrogenic thermal trauma of the teeth have a significant impact on the dental pulp structure connected with stimulation of angiogenesis and lymphangiogenesis. Therefore, the aim of the study was to identify the difference in the rate of heat dissipation by vessels present in the dental pulp. Methods Freshly extracted healthy and...

Backgrounds: The titanium–aluminum–vanadium alloy (Ti-6Al-4V) is frequently used in implantology due to its biocompatibility. The use of 3D printing enables the mechanical modification of implant structures and the adaptation of their shape to the specific needs of individual patients. Methods: The titanium alloy plates were designed using the 3D C...

This paper investigates trabecular bone ontogenetic changes in two different Polish populations, one prehistoric and the other historical. The studied populations are from the Brześć Kujawski region in Kujawy (north-central Poland), one from the Neolithic Period (4500–4000 BC) and one from the Middle Ages (twelfth-sixteenth centuries AD), in total...

Osteoporosis stands out as a prevalent skeletal ailment, prompting exploration into potential treatments, including dietary strontium ion supplements. This study assessed the efficacy of supplementation of three strontium forms—strontium citrate (SrC), strontium ranelate (SrR), and strontium chloride (SrCl)—for enhancing bone structure in 50 female...

Purpose Construction of the orthodontic bracket promotes food accumulation, which is the cause of plaque formation. Modern trends in the design of adhesive orthodontic cements focus on the ability to release cariostatic fluoride ions. One of the methods is to incorporate the material with fluorapatite nanoparticles. The aim of the study was to dete...

Purpose The aim of this study was to examine a short-term (7 days) fluoride ions release and mechanical properties (microhardness) of dental materials - resin-modified glass- ionomer – Vitremer (3M ESPE) and nanohybrid universal composite - TetricEvoCeram (IvoclarVivadent) to assess whether both materials may constitute effective method of tooth de...

Electrospinning is an increasingly popular technique for obtaining scaffolds for skin regeneration. However, electrospun scaffolds may also have some disadvantages, as the densely packed fibers in the scaffold structure can limit the penetration of skin cells into the inner part of the material. Such a dense arrangement of fibers can cause the cell...

Preformed stainless steel crowns are used in pediatric dentistry to obtain full crown restoration of primary molar teeth. They are consider the best restoration in terms of durability and effectiveness. The purpose of this study is to evaluate microbial, cytological and physio-chemical properties to determine whereas stainless steel crown are bioco...

Simple Summary The goal of this study was a detailed analysis of the mandibular teeth structure of the Komodo dragon (Varanus komodoensis), based on macroscopic, histological and computed microtomography examinations. The samples were collected post mortem from two adult female Komodo dragons from Wroclaw Zoo. Macroscopically, each mandibular tooth...

In this work, composite filaments in the form of sticks and 3D-printed scaffolds were investigated as a future component of an osteochondral implant. The first part of the work focused on the development of a filament modified with bioglass (BG) and Zn-doped BG obtained by injection molding. The main outcome was the manufacture of bioactive, strong...

The current fashion for healthy food and the increasing number of people with lactose intolerance make fermented vegetables increasingly important. On top of this, surpluses unused in the vegetable harvest can become a potential source of “green waste”. The use of fermentation and freeze-drying can result in a valuable, sustainable product that can...

Purpose: Bone fractures are one of the most commonly seen problems in veterinary traumatology. The authors of this study strive to find a new intramedullary nail, which is intended for treating femoral bone fractures for canine patients. The purpose of this study was to analyze biomechanical parameters of the intramedullary nails, which use a new b...

The aim of the current study was to to investigate the influence of cornelian cherry (Cornus mas L.; CM) extract on ovariectomy-induced metabolic changes including bone loss, obesity development, adipokines imbalance and oxidative stress. Intragastrical administration of CM ameliorated ovariectomy-induced weight gain and decreased accumulation of v...

Simple Summary The present study aimed to determine the possibility of limiting potential dioxin disorders of the structure of hard tissues in the offspring of intoxicated rat mothers by simultaneous administration of α-tocopherol (vitamin E) or acetylsalicylic acid (ASA). The levels of magnesium (Mg), calcium (Ca) and phosphorus (P) contained in b...

The main purpose of this study is to analyse the temperatures generated during the bone bed preparation, given the internal structure of the bone bed, the geometry of the hole, and the treatment parameters such as the type of cooling and the rotational speed of the drill. The investigated material was domestic pig ribs, in which holes were drilled...

The aim of the study was to investigate in animal model the influence of hops prenylflavonoids on hot flashes and bone loss. Xanthohumol (XN) and hop prenylflavonoids extract (HOP) restored twenty-four-hour variability of tail skin temperature in ovariectomized rats. Additionally XN and HOP increased femoral bone mineral density (BMD) (0.268 ± 0.01...

Osteoporosis is a skeletal disease associated with excessive bone turnover. Among the compounds with antiresorptive activity, nitrogen-containing bisphosphonates play the most important role in antiosteoporotic treatment. In previous studies, we obtained two aminomethylidenebisphosphonates—benzene-1,4-bis[aminomethylidene(bisphosphonic)] (WG12399C)...

Purpose Healing of osteoporotic defects is challenging and requires innovative approaches to elicit molecular mechanisms promoting osteoblasts-osteoclasts coupling and bone homeostasis. Methods Cytocompatibility and biocompatibility of previously characterised nanocomposites, i.e Ca5(PO4)3OH/Fe3O4 (later called nHAp/IO) functionalised with microRN...

Highly active antiretroviral therapy (HAART) is used in HIV-infected patients. Alongside the prolongation of patients’ life, adverse side effects associated with long-term therapy are becoming an increasing problem. Therefore, optimizing of HAART is extremely important. The study is aimed at evaluating the toxicity of abacavir and etravirine in mon...

Bone structure abnormalities are increasingly observed in patients chronically treated with antiepileptic drugs (AEDs). The majority of the available data concern older conventional AEDs, while the amount of information regarding newer AEDs, including stiripentol, is limited. The aim of the study was to assess the effect of stiripentol on bones. Fo...

We sought to evaluate the effects of Er:YAG laser (LightTouch, LightInstruments, Israel) conditioning on enamel roughness and shear bond strength of orthodontic brackets on enamel. Eighteen human molars (n = 9) and premolars (n = 9), were divided into 3 groups depending on the enamel conditioning method; Er:YAG laser (G1, n = 6), conventional etchi...

Background: Clinical trials indicate an increased risk of osteoporosis and bone fractures in people infected with human immunodeficiency virus (HIV). The pathogenesis of bone disturbances in HIV-positive patients is unknown, but it is suggested that antiretroviral drugs may be involved. Objectives: To assess the effects of efavirenz (EF) and ten...

Purpose: The main goal of this article was the analysis of the changes of mechanical properties, thickness and histology of the cartilage in different regions of the femur head in advanced stage of the osteoarthritis. Methods: The study material consisted of cylindrical specimens (9.7 mm) prepared form proximal epiphysis of the human femur bone...

The aim of the study was to investigate the effect of physical training on bone parameters of rats exposed to alcohol (Al) and/or cadmium (Cd). Young female rats were divided into one control group and six groups exposed to Cd and/or Al. Al (36% calories of diet) and Cd (20 mg Cd/kg feed) were administered with liquid diet. Half of the rats from th...

Purpose: The aim of this study is to evaluate the influence of the swimming speed during diving on the biomechanical parameters describing the movement of selected measurement points of the lower limb in professional divers. Methods: The study involved a group of 4 professional divers whose movement was recorded during underwater swimming at slo...

The main goal of the presented study was to identify the raw material of V-shaped buttons found in the archaeological site of Sandomierz-Hill Zawichojskie (Poland). Particularly important here was to determine whether the buttons are made of a material commonly available (bones of domestic animals) or exotic (eg. ivory), which could indicate a supr...

Background: Postmenopausal osteoporosis and osteoporotic fractures constitute an increasing problem in developing countries. Kaempferol, isolated from seeds of Cuscuta chinensis, is an active flavonoid inhibiting in vitro osteoclast activity. The aim of the presented research was an assessment of kaempferol effect on estrogen-deficiency-induced bo...

Bone tissue is a biological system in which the dynamic processes of, among others, bone formation or internal reconstruction will determine the spatial structure of the tissue and its mechanical properties. The appearance of a factor disturbing the balance between biological processes, e.g. a disease, will cause changes in the spatial structure of...

The implementation of new methods of osteoporotic therapy requires tests on animal model. The use of sheep as model has numerous advantages over other animals. The aim of this study was to describe the change in parameters in sheep with osteoporosis induced using steroids and ovariorectomy methods as opposed to the parameters in healthy sheep. The...

Background: Drug-induced osteoporosis is a significant health problem, as many drugs have deleterious effects on bone metabolism. Data from several studies concerning the influence of retinol on bone homeostasis are inconsistent. Objectives: The purpose of this study was to investigate the influence of tazarotene, a selective agonist of the reti...

The implementation of new methods of oseoporotic therapy requires tests on an animal model. One of the best is the sheep, whose numerous advantages over other models are described in the literature. The aim of this study was induction of osteoporosis using steroids and ovariorectomy methods in sheep and description of the change in parameters with...

Purpose: The purpose of this study was to investigate the influence of selective agonists of the retinoid receptor X (RXR) and the retinoid acid receptor (RAR) on bone metabolism in rats. Methods: Thirty six male Wistar rats were divided into three groups: receiving bexarotene, or tazarotene, or to control group. Serum biochemical markers of bon...

Słowa kluczowe: osteoartroza, kość udowa, remodeling, MES 1. WSTĘP Osteoartroza (OA) jest chorobą która dotyczy ponad 135 milionów ludzi na całym świecie. Charakteryzuje ją skomplikowany przebieg oraz brak jednoznacznie określonych przyczyn powstawania. Zmiany zwyrodnieniowe mogą występować w obrębie stawu kolanowego (gonartroza), stawu biodrowego...

Aims Tomography as imaging by sections is the method not only used in medicine but also in live science and moreover in material science, by using the different ratio of the X-rays absorption allows to distinguish sections with distinct density. The method is included in noninvasive measuring techniques giving the opportunity to examine the specime...

Streszczenie: Zmiany geometrii kości spowodowane rozwojem osteoartrozy (OA) dotyczą coraz szerszej populacji. Skomplikowany przebieg choroby wymaga prowadzenia dokładniejszych badań mechanizmów powstawania choroby. W pracy przeprowadzono analizę numeryczną przebudowy tkanki gąbczastej kości udowej według dwóch modeli przebudowy (model Tsuboty oraz...

Streszczenie: W pracy przedstawiono badania właściwości strukturalnych tkanki kostnej przeprowadzone z wykorzystaniem mikrotomografu rentgenowskiego. Materiał badawczy stanowiły nasady bliższe kości udowych pacjentów, u których stwierdzono chorobę zwyrodnieniową. Celem badań było określenie wpływu zmian warunków mechanicznych w stawie biodrowym na...

Degenerative joint disease known as osteoarthritis (OA), changes the mechanical conditions in joint and stimulate the bone remodeling, as OA is progressing the breakdown of cartilage and deformation of femoral head are observed. Those changes have impact on mechanical properties of the femoral trabecular bone and can be correlate with the stages of...

Celem badań było określenie właściwości mechanicznych oraz strukturalnych tkanki kostnej gąbczastej pochodzącej z nasad bliższych kości udowych. Materiał badawczy pochodził od pacjentów z chorobą zwyrodnieniową o zróżnicowanym stopniu zaawansowania. Porównując wyniki właściwości strukturalnych i mechanicznych próbek pochodzących z różnych regionów...

The aim of the study was to assess the influence of various feed phosphates on the structural and mechanical properties as well as on the chemical composition of femurs in adult pigs (weight approx. 110 kg). Three types of phosphates--monocalcium phosphate (MCP), dicalcium phosphate (n-DCP) and calcium-sodium phosphate (CSP)--were used alternativel...

In this article, the author presents mathematical relationships between the structural and mechanical properties of cancellous human bone tissue obtained by experimental analysis of specimens. Bone tissue material can adjust its internal structure to the existing loading conditions. The mechanical properties affect the structural properties but cha...

The knowledge of the mechanical characteristics of bone structures is a prerequisite for theoretical, numerical, and experimental analyses describing the functioning of bone, which is a living organ. The description of the mechanical properties of bone tissue, such as conventional Young's modulus or strength, will enable the assessment of the degre...

The function of bone tissue, which is a very complex material, is due to the structure and mechanical properties. According to Wolffs law, the permanent loaded hip is wellmotivated and adapts his inner and outer architecture to the environment. The body mass is transferred through the femur bone, where the trabeculae aligns along stress trajectorie...