Anna-Karin Danielsson

Karolinska Institutet | KI · Department of Global Public Health

Background and Purpose—Current knowledge on cannabis use in relation to stroke is based almost exclusively on Clinical reports. By using a population-based cohort, we aimed to find out whether there was an association between cannabis use and early-onset stroke, when accounting for the use of tobacco and alcohol. Methods—The cohort comprises 49 321...

Aims To examine: (a) to what extent individuals in contact with heath care had been asked and advised on their alcohol habits; (b) how self-reports of alcohol consumption and patient characteristics affected the probability of being asked and advised on alcohol consumption; (c) the potential effect of alcohol advice on readiness and ability to chan...

Aims: Whether or not cannabis use may increase or decrease the risk of type 2 diabetes is not clear. We analyzed the association between cannabis and subsequent type 2 diabetes, and if a potential positive or reverse association persisted after controlling for potential confounders. Methods: This population-based cohort study with 17,967 Swedish me...

Aims: To compare alcohol-attributed disease burden in four Nordic countries 1990-2013, by overall disability adjusted life years (DALYs), and separated by premature mortality (YLL), and health loss to non-fatal conditions (YLD), 2) to examine whether changes in alcohol consumption informs alcohol-attributed disease burden and 3) to compare the dis...

Background: Previous studies have reported positive associations between cannabis use and mental health problems. However, it has not been possible to draw a definitive conclusion regarding the causal direction between cannabis use and impaired mental health. This study aimed at examining possible associations between cannabis use and psychologica...

Objective The purpose of this study is to examine the prevalence of indications of alcohol or drug use disorders in five different national Swedish registers and to investigate the correlation between these registers. Furthermore, the intent is to investigate whether combining data from different registers increases the prevalence of these indicati...

The Nordic countries share similarities in many social and welfare domains, but drug policies have varied over time and between countries. We wanted to compare differences in mortality and disease burden attributed to drug use over time. Using results from the Global Burden of Disease (GBD) study, we extracted age-standardized estimates of deaths,...

Background: Substance use problems have been associated with poor labour market outcomes. This study investigated whether substance use disorders (SUD) in emerging adulthood increase the likelihood of later being not in employment, education or training (NEET). Methods: A national cohort study of 23 5295 males and 227 792 females born between 19...

Objective: To investigate the associations between low education and risk of mental disorders, substance use disorders and self-harm in different age-groups. Methods: All subjects in Stockholm born between 1931 and 1990 were linked to their own or their parent's highest education in 2000 and followed-up for these disorders in health care registe...

Background and aim: Cannabis use disorder (CUD) is one of the main reasons for seeking substance treatment in the Nordic countries, yet there are few studies on readmission to care. We aimed to characterize CUD readmission and estimate the magnitude of how socioeconomic factors and psychiatric comorbidity influence the risk of CUD readmission. De...

Background:Cannabis use disorder (CUD) is one of the main reasons for seeking substance use treatment. It is thus important to monitor and increase knowledge of individuals with CUD utilizing healthcare. We aimed to examine the number of CUD diagnoses over time, compare individuals with CUD with those without and identify subgroups based on CUD dia...

Background: Poverty in adolescence is associated with later drug use. Few studies have evaluated the role of adolescent psychiatric disorders in this association. Aims: This study aims to investigate mediation and interaction simultaneously, enabling the disentanglement of adolescent psychiatric disorders in the association between poverty in adole...

Background Few studies have assessed how children are affected by parental alcohol consumption without clinically diagnosed alcohol problems, especially in relation to more long-term and severe consequences. The aim is to investigate how fathers’ alcohol use is related to the risk for substance-related disorders in offspring. Method A prospective...

Background: Being not in education, employment, or training (NEET) has been associated with poor health outcomes. This study aimed to investigate the association between NEET during emerging adulthood and later drug use disorder (DUD) among males and females. Method:A national cohort comprising 383,116 Swedish males and 362,002 females born betwee...

Aims To test the hypothesis that exposure to parental substance use disorder is associated with an increased risk of being not in education, employment or training (NEET) in male and female offspring during young adulthood. Design, setting and participants A register-based, national cohort study of 797,376 individuals born between 1984 and 1990, r...

Background Pharmacotherapy for alcohol use disorders (AUD) is effective. However, knowledge about utilization of, and patient characteristics associated with prescriptions is scarce. The aim is to investigate prescriptions of pharmacotherapy for AUD in Sweden across time, sociodemographics, domicile and comorbid conditions. Method This is a nation...

Background The proposed ICD-11 classification includes major revisions of alcohol dependence. We aimed to evaluate the presence of, and concordance between the proposed ICD-11 dependence and ICD-10, DSM-5, DSM-IV, DSM-III-R and DSM-III in a general population. We also examine as aspects of validity, including longitudinal stability and how meaningf...

ABSTRACT Aims To examine whether poverty exposure in childhood/adolescence increases the risk of later drug use disorder and drug crime conviction. Design, Setting, and Participants A national cohort study encompassing 634,284 individuals born between 1985 and 1990, residing in Sweden between 5 to 18 years of age, followed up from January 2004 t...

Introduction and Aims The gender difference in alcohol use seems to have narrowed in the Nordic countries, but it is not clear to what extent this may have affected differences in levels of harm. We compared gender differences in all‐cause and cause‐specific alcohol‐attributed disease burden, as measured by disability‐adjusted life‐years (DALY), in...

Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardise...

Background: The associations between cannabis use and anxiety or depression remain unclear. If cannabis affects these conditions, it is of interest to examine possible changes in cannabis use over time, in relation to anxiety and depression, as cannabis potency has increased in recent decades. Methods: Cohorts from the Women and Alcohol in Gothenbu...

Introduction and Aims Results from previous research are inconsistent regarding the association between socioeconomic status (SES) and cannabis use among adolescents. Since there are risks associated with cannabis use, a social gradient in cannabis use may contribute to reproducing socioeconomic differences in life opportunities. The aim of this st...

Aims: To examine the association between cannabis use and subsequent other illicit drug use and drug use disorders (harmful use and dependence). Design, Setting, Participants: We used survey data from a population-based cohort in Stockholm County (collected 1998–2000), with linkage to the National Patient Register. The study base comprised particip...

Objectives To coherently examine the responsiveness of the Swedish National Tobacco Quitline (SNTQ) to different types of anti-smoking policies over an extended period of calendar time. Design Quasi-experimental design with an intervention time-series analysis based on 19 years series of data collected between January 1999 and August 2017 (224 mon...

Objective To investigate to what extent being outside education, employment or training after completed secondary education in Sweden might affect the risk of subsequent alcohol use disorders (AUDs), with sociodemographic indicators, such as sex, domicile and origin, taken into account. Design: Population register-based cohort study with 485 839 S...

Cannabis and its effects on health and society are a much debated topic both in Sweden and internationally. The debate is often defined by polarised rhetoric. This report examines what current research says about cannabis and health, cannabis and social problems, and cannabis for medicinal use. Cannabis is one of the most widely used drugs in the...

Objective: To examine the association between various indicators of father's alcohol use and suicidal behaviour in offspring during youth and young adulthood METHODS: The study is based on a cohort of 68 910 Swedish citizens that were born between 1970 and 1985 and have fathers that participated in conscription for compulsory military training in...

Objective: Screening and brief intervention in primary care for hazardous alcohol use is potentially a means to improve public health but is seldom implemented. There are few comparisons with general practitioner screening for other lifestyle habits. Method: Repeated cross-sectional surveys from 2004, 2008, and 2012 in Sweden were used (N = 28,9...

Background A primary concern within the healthcare system is to make treatment more accessible as well as attractive for the great majority of alcohol-dependent people who feel reluctant to participate in the treatment programs available. This paper presents the protocol for a randomized controlled trial (RCT) to test the efficacy of two different...

Aim This study examined associations between fathers’ alcohol consumption and risk for total and cause-specific mortality in offspring. Short summary We examined the associations between fathers’ alcohol consumption and total and cause-specific mortality in adult offspring. Fathers’ alcohol consumption was associated with increased risk of alcoh...

Aims: To examine if changes in alcohol consumption are associated with changes in cannabis use among Swedish adolescents in a period of diverging trends, and to investigate if cannabis and alcohol act as complements or substitutes. Design, setting, participants and measurements: Data comprise a nationally representative annual school survey of a...

Aims: We investigate (a) alcohol consumption in association with type 2 diabetes, taking heavy episodic drinking (HED), socioeconomic, health and lifestyle, and psychosocial factors into account, and (b) whether a seemingly protective effect of moderate alcohol consumption on type 2 diabetes persists when stratified by occupational position. Meth...

Previous studies in Sweden have focused on a number of indicators to assess and compare health conditions at regional levels over time. In this study we aimed to give a more complete picture of the health situation in Stockholm County compared to the rest of Sweden, by using the DALY measure (disability-adjusted life years). DALY combines life lost...

Aims: To assess alcohol consumption and alcohol-attributed disease burden by DALYs (disability adjusted life years) in the BRICS countries (Brazil, Russia, India, China and South Africa) between 1990 and 2013, and explore to what extent these countries have implemented evidence-based alcohol policies during the same time period. Design: A comparat...

First, we express our appreciation of the comments on our study by Kawada and by Behrouz and Aachi. We seem to agree on the value of studies on this matter. In both letters, the authors highlight that cannabis use in our study (as well as tobacco and alcohol use) could be measured only in late adolescence and, as a result, little is known about its...

Introduction: The aim of the present study was to investigate the association between exposure to fathers’ alcohol consumption and offspring’s own risk of alcohol-related hospitalization. Methods: Data on circumstances in childhood and adolescence, e.g. fathers’ alcohol consumption at different levels (never, rarely, occasionally, often), parental...

Supporting info item

Aim: The Global Burden of Disease (GBD) study continuously refines its estimates as new data and methods become available. In the latest iteration of the study, GBD 2013, changes were made related to the disease burden attributed to alcohol. The aim of this study was to briefly present these changes and to compare the disease burden attributed to...

Background Whether or not cannabis use may increase the risk for depression and/or anxiety is not clear. For one thing, it has not been possible to draw a definitive conclusion regarding the direction of causality, i.e. whether cannabis use increases the risk for depression/anxiety or vice versa. This study aimed at examining possible associations...

To examine associations between cannabis use in adolescence (at age 18) and unemployment and social welfare assistance in adulthood (at age 40) among Swedish men. Longitudinal cohort study. 49 321 Swedish men born in 1949-1951, who were conscripted to compulsory military service at 18-20 years of age. All men answered two detailed questionnaires at...

Aims To study the prevalence of cannabis use and drug-related problems among European adolescents and the utility of the prevention paradox. Methods Survey data from the European School Survey Project on Alcohol and Other Drugs (ESPAD) in 2007 in the 27 countries with information about drug use and drug-related problems was used. We analysed the p...

Aims This study aimed at examining a possible association between cannabis use in adolescence and future disability pension (DP). DP can be granted to any person in Sweden aged 16 to 65 years if working capacity is judged to be permanently reduced due to long-standing illness or injury. Methods Data were obtained from a longitudinal cohort study c...

The aim of the study was to investigate preferences in the general population regarding type of treatment for alcohol problems and the preferred setting for delivery of treatment and reasons for not seeking treatment for alcohol problems. Method: Data were from a random, cross-sectional, interview survey of 9005 of the Swedish general population. P...

Background: The prevention paradox states that a majority of alcohol-related problems in a population come from moderate drinkers because they are more numerous than heavy drinkers, although the latter have a higher individual risk of adverse outcomes. We examined the extent to which the prevention paradox applies to the relationship between alcoh...

According to the prevention paradox, a majority of alcohol-related problems in a population can be attributed to low to moderate drinkers simply because they are more numerous than heavy drinkers, who have a higher individual risk of adverse outcomes. We examined the prevention paradox in annual alcohol consumption, heavy episodic drinking (HED) an...

This longitudinal study examined possible gender differences regarding risk and protective factors for heavy episodic drinking among 1,222 seventh-grade students (aged 13) in the City of Stockholm, Sweden, with follow-up 2 years later. Logistic regression analyses showed that several factors predicted heavy episodic drinking. The strongest predicto...

This study aimed at identifying different alcohol drinking trajectories in early to late adolescence. We also examined whether certain factors predicted membership of a specific trajectory and to what extent trajectory membership was linked to later negative consequences. Data were drawn from a longitudinal cohort study starting with 1923 adolescen...

Local alcohol and drug use prevention in Sweden has witnessed a substantial surge in recent years, with government funding for local coordinators in every municipality. Whether this has contributed to the recent decline in alcohol use among young people is unknown. The ESAPP project evaluates local alcohol and drug prevention in the 18 municipaliti...