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October 2013 - April 2014
October 2003 - September 2013
Publications
Publications (123)
The breech position is a variant of presentation, which occurs in ca. 3–6% of pregnancies at term. After prenatal counseling and shared decision-making, first an external cephalic version and thereafter a cesarean section (planned or at onset of labor) or a vaginal delivery from the breech position can be offered. At present a vaginal delivery is o...
Durch die Ausrichtung des kindlichen Rückens und des kindlichen Kopfes kommt es bei der dorsoposterioren Lage zu einer ungünstigen Führungslinie. Handgriffe wie die digitale oder manuelle Rotation bieten eine Chance, die Lage zu korrigieren. Gelingt das Manöver, lassen sich möglicherweise eine vaginal-operative Geburt oder ein Kaiserschnitt vermeid...
Women pregnant with a breech-presenting fetus at term are at an increased risk of adverse outcomes. Although the most common intervention is planned delivery by caesarean section, this is not always possible or desirable. Comparing alternative interventions is difficult due to heterogeneity in reported outcomes and their measurements. Additionally,...
Breastfeeding (BF) in mothers living with HIV (MLWH) is still discussed controversially in resource-rich settings. In Germany, where formula feeding is recommended for MLWH single BF cases have been reported, but no systematic data collection and analysis are available so far. This study, titled HELENE, aims to fill this data gap. A questionnaire c...
Bei der Beckenendlage handelt es sich um eine Lageanomalie, die in 5 % der Schwangerschaften auftritt. Eine vaginale Entbindung ist für viele Schwangere möglich, ausschlaggebend ist hier die korrekte Selektion der Schwangeren. Ab der 36+0 SSW kann eine äußere Wendung versucht werden, um die Rate der Schädellagen am Termin zu erhöhen. Selbstwendetec...
Background:
We aimed to identify common features of upright vaginal breech births with good outcomes to refine a physiological approach to teaching breech birth.
Methods:
We performed a structured analysis of 42 videos of successful upright breech births (eg, kneeling, hand/knees), facilitated by obstetricians (n = 34) and midwives (n = 8) in ni...
Die Beckenendlage kommt bei 3–5 % aller Schwangeren im dritten Trimester vor. Die Expertise, eine Geburt aus Steißlage zu beglei- ten, liegt heute nicht mehr flächendeckend vor. Das notwendige Wissen und das Handwerk sind in Deutschland und weltweit teils verloren gegangen.
Introduction An independently managed, specialized obstetric unit in a small hospital setting resulted in measurable changes in quality of maternity care.
Material and methods We present obstetric data from a level I (basic care) hospital in Frankfurt, Germany. We compare data from the mandatory state register collected in 2013, when the obstetrics...
Our primary objective was to compare neonatal and maternal outcomes in women with twin pregnancies, beyond 32 weeks, having a planned vaginal birth or a planned caesarean section (CS). This was a retrospective cohort study from a single tertiary centre over nine years. 534 sets of twins ≥32 + 0 weeks of gestation were included. 401 sets were planne...
Our primary objective was to compare neonatal and maternal outcomes in women with twin pregnancies, beyond 32 weeks, having a planned vaginal birth or a planned caesarean section (CS). This was a retrospective cohort study from a single tertiary centre over nine years. 534 sets of twins ≥32 + 0 weeks of gestation were included. 401 sets were planne...
Objective:
To compare breech outcomes when mothers delivering vaginally are upright, on their back, or planning cesareans.
Methods:
A retrospective cohort study was undertaken of all women who presented for singleton breech delivery at a center in Frankfurt, Germany, between January 2004 and June 2011.
Results:
Of 750 women with term breech de...
Co-infection with CMV in HIV-positive pregnant women is associated with perinatal mother-to-child transmission (MTCT) of both viruses. This retrospective study reports on the incidence of maternal and neonatal CMV (presence of anti-CMV IgG and IgM, CMV DNA PCR and/or CMV virus isolation) in high-risk pregnancies due to maternal HIV infection, MTCT...
Objectives
To assess the impact of different positions on pelvic diameters by comparing pregnant and non pregnant women who assumed a dorsal supine and kneeling squat position.
Study Design
In this cohort study from a tertiary referral centre in Germany, we enrolled 50 pregnant women and 50 non-pregnant women. Pelvic measurements were obtained wit...
Zielsetzung: Beurteilung der Beckenmase im MRT bei jungen Probandinnen und Schwangeren mit Beckenendlage in verschiedenen geburtshilflichen Stellungen. Material und Methodik: Im Rahmen dieser prospektiven Studie wurden bei 50 gesunden Probandinnen und 50 Schwangeren mit Beckenendlage im letzten Trimenon die Beckenmase im MRT (Magnetom Espree; Sieme...
Objectives
The aim of the study was to assess pregnancy complications in HIV-positive women and changes in the rates of such complications over 11 years in the Frankfurt HIV Cohort. Methods
There were 330 pregnancies in HIV-positive women between 1 January 2002 and 31 December 2012. The rate of pregnancy-related complications, such as gestational d...
The aim of this investigation was to evaluate the outcome at 20 to 24 weeks gestation of twin and singleton extremely low birth weight infants.
The authors conducted a retrospective cohort study of live newborns at 20 to 24 weeks gestation admitted to one neonatal intensive care unit (NICU) from 2000 to 2009. Outcome mortality and predictors of out...
Es wird vermutet, dass Feten mit Lippen-Kiefer-Gaumen-Spalte (LKG) eine Funktionsveranderung im orofazialen Bewegungsmuster aufweisen. Die Quantifizierung einer solchen Storung und daraufhin die fruhzeitige Erstellung eines individualisierten Behandlungsplanes erscheint sinnvoll. Mittels erweiterter pranataler Ultraschalluntersuchung soll die Funkt...
The majority of women living with HIV are of childbearing age and many of these women wish to have a family. As a result of advances in the treatment and management of HIV, more reproductive opportunities are now available to this group. However, women living with HIV may still require education and guidance in a range of reproductive situations, i...
Objective:
To assess the prevalence of prenatal screening and of adverse outcome in high-risk pregnancies due to maternal HIV infection.
Study design:
The prevalence of prenatal screening in 330 pregnancies of HIV-positive women attending the department for prenatal screening and/or during labour between January 1, 2002 and December 31, 2012, wa...
PURPOSE
The aim of this study was to evaluate whether pelvic dimensions changes with pregnancy or different birthing positions.
METHOD AND MATERIALS
MR pelvimetry was performed in 20 nonpregnant female volunteers and in 13 women with a fetus in a breech presentation in an 1.5-T MR imaging system (Magnetom Espree; Siemens, Erlangen). The femals wer...
Three to four percent of full-term singleton pregnancies present themselves as breech deliveries. External cephalic version (ECV) is a procedure to try to turn a breech fetus to cephalic by externally maneuvering the fetus through the maternal abdomen. This trial examines a clinical hypnosis intervention against standard medical care of women befor...
Aim: Aim of the study was to show that conservative management with preservation of the uterus and of fertility is possible in patients with placenta accreta/increta after vaginal delivery. Method: A retrospective analysis of patients with placental attachment disorders after vaginal delivery was done in a perinatal centre between November 2009 and...
Objective:
This study aimed to know the outcome of delayed-interval delivery for twin and triplet pregnancies at 22+0 to 25+0 weeks of gestation.
Study design:
A retrospective cohort of twin and triplet deliveries at the 23rd to 26th weeks of gestation were managed with delayed interval delivery from 2005 to 2011.
Results:
From 2005 until 2011...
Tumor progression and pregnancy share many common features, such as immune tolerance and invasion. The invasion of trophoblasts in the placenta into the uterine wall is essential for fetal development, and is thus precisely regulated. Its deregulation has been implicated in preeclampsia, a leading cause for maternal and perinatal mortality and morb...
The cesarean section rate and the associated complications are still rising in Germany. An important indication is term breech in singletons. Not significant data concerning a higher morbidity or mortality in vaginal breech birth indicate the cesarean but a deficit in education and experience.
© Georg Thieme Verlag KG Stuttgart · New York.
Fetal malignant tumors are rare. We present a case of intrauterine diagnosis of a diaphragmatic tumor presenting with fetal hydrops at 32 weeks' gestation. The sonographic findings were bilateral pleural effusion, ascites and skin edema. A large right-sided diaphragmatic tumor was identified. Owing to the findings on ultrasound and magnetic resonan...
Holoprosencephaly (HPE) is a serious malformation of the central nervous system which occurs between the 18th and 28th day of gestation. HPE can appear in different manifestations within one family. The diagnosis of HPE can be performed in an early sonographic scan between the 12th and the 14th week of gestation, according to the guidelines for the...
Human cytomegalovirus (CMV) is considered as the most common cause of congenital infection in humans and the overall burden for the public health system is rather high. About 1/10 of vertically infected newborns present or develop severe signs of cytomegalic inclusion disease (CID), with the classical triad of chorioretinitis, microcephaly and cere...
Gestational diabetes (GDM) is related to increased maternal and neonatal morbidity. Maternal hyperglycemia causes fetal hyperglycemia and consequently fetal hyperinsulinism. The impaired glucose metabolism will lead to prenatal and postnatal complications. The main issue of this study is the influence of GDM in evaluating Doppler flow measurements...
Prenatal diagnosis of generalized arterial calcification of infancy (GACI) (OMIM #208000) is difficult and rare. There are various known gene mutations in ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) locus 6q22-q23. We present a case of suspected intrauterine diagnosis at 29 weeks of gestation in a consanguineous couple. The sonograph...
Introduction: Translocations occur approximately 1 in 500 newborns. Individuals who carry balanced translocations produce in 50% unbalanced gametes. In the reported case the resulting phenotype almost always includes developmental delay and congenital anomalies. Case presentation: The 32-years-old pregnant female, gravida 3, para 1, was referred to...
Einleitung: Eklampsie und Epilepsie sind die haufigsten Ursachen eines Krampfanfalls in der Schwangerschaft. Ein erstmals in der Schwangerschaft aufgetretener Krampfanfall, insbesondere im spaten 2. oder 3. Trimenon bei Patientinnen ohne vorbeschriebene Epilepsie, wird daher meist als Eklampsie gedeutet und resultiert in den entprechenden Entbindun...
The aim of this study was to assess the frequency of side effects of antiretroviral treatment in transmission prophylaxis in preterm and near-term infants with a history of HIV-positive mothers.
A retrospective single-centre study of all neonates born to HIV-positive mothers between 2001 and 2005 and receiving antiretroviral prophylaxis was perform...
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