Anjana Goel

Anjana Goel
GLA University · Institute of Applied Science & Humanities

M.Sc (Biochemistry); PhD

About

71
Publications
35,419
Reads
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419
Citations
Additional affiliations
April 2005 - August 2009
College of Veterinary Sciences and Animal Husbandry
Position
  • Woman Scientist
Description
  • Principal Investigator in DST sponsored project under WOS-A scheme
April 2005 - August 2009
Pandit Deen Dayal Petroleum University
Position
  • Woman Scientist DST

Publications

Publications (71)
Preprint
Cryptosporidium spp. is the most important foodborne and waterborne pathogens and leading cause of mortality from foodborne and waterborne gastrointestinal diseases. In neonates of domestic animals, it is associated with consistent diarrhoea and dehydration. Cryptosporidium infection begins with the ingestion of sporulated oocytes disseminated by c...
Article
The nanoparticle is one of the most intensively studied areas in science ranging from engineering to medical fields and has been a center of attraction that is explored to find new and promising dimensions for its use. These nanoparticles have obtained eminence because of their potential efficacy, shape, and size. In the field of nanoscience, the u...
Article
Mucormycosis is a deadly opportunistic disease caused by a group of fungus named mucormycetes. Fungal spores are normally present in the environment and the immune system of the body prevents them from causing disease in a healthy immunocompetent individual. But when the defense mechanism of the body is compromised such as in the patients of diabet...
Preprint
Cryptosporidium spp. is the most important foodborne and waterborne pathogens and the leading cause of mortality from foodborne and waterborne gastrointestinal disease. In neonates of domestic animals it is associated with consistent diarrhoea and dehydration. Cryptosporidium infection begins with the ingestion of sporulated oocytes disseminated by...
Thesis
Full-text available
The presence of viable M. leprae in clinical and environmental sources with similar copy number of 16S rRNA indicated that bacilli present in both samples might be sufficient to cause infection to susceptible individual. Continuous shedding of viable bacilli from active MB patients into the natural setting might be acting as a source of infection t...
Article
Full-text available
The medicinal potential of Lawsonia inermis Linn, different fractions of its leaves extract was investigated for its immunomodulating potential by studying its effect on splenocyte proliferation and altering the expression of IL-2 and IL-4 cytokines in in vitro system. Hexane (HLE), ethyl acetate (ELE) and methanolic (MLE) fractions of leaves extra...
Article
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Argemone mexicana, a prickly plant commonly called as prickly poppy is found in sub tropical regions and is well known for its medicinal properties. Its potential as a medicinal plant has been practiced traditionally and been prescribed as medicines by Ayurvedic, Unani, Siddha and Homeopathic practices since several years. Each part of plant posses...
Article
Full-text available
Although leprosy is curable, the identification of biomarkers for the early diagnosis of leprosy would play a pivotal role in reducing transmission and the overall prevalence of the disease. Leprosy-specific biomarkers for diagnosis, particularly for the paucibacillary disease, are not well defined. Therefore, the identification of new biomarkers f...
Article
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Cosmetics has been used, since ancient times, for enhancing the beauty and self-care. But the difference lies in the chemicals that have been constantly used for the manufacturing of cosmetics in the present timeconcerning the natural cosmetics that were been in use in ancient civilization and still used by many people. Many controversies arose in...
Article
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The potential role of environmental M. leprae in the transmission of leprosy remains unknown. We investigated role of environment as a possible source of viable M. leprae responsible for transmission of leprosy. The samples were collected from 10 multi-case leprosy families comprising, slit skin smear (SSS) from 9 multibacillary (MB), 16 paucibacil...
Article
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Murraya koenigii, commonly known as curry leaves, is a well-known spice and natural flavouring substance used in Indian households for preparing delicacies. It is of Indian origin, easily available throughout the year and has been a constituent of many Ayurvedic medicines since old age. It has been used traditionally by the folks to cure ailments b...
Article
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The current global health emergency, COVID-19, is not the first time that coronaviruses have posed a threat to human world shrinking our numbers by thousands. Before this SARS-CoV in 2003 and MERSCoV in 2013 have caused epidemics. Four months in existence, and it has already affected 1,995,983 people and taken over 131,037 lives worldwide, yet we d...
Article
Full-text available
The aim of this study is to evaluate and validate the Immunomodulating potential of medicinal plants Murraya koenigii and Datura stramonium L. which are known in Ayurvedic literature for the remedy of various alignments. Chemical constituents present in the leaves of Murraya koenigii and Datura stramonium, accounted for its anti-cancer, anti-nocice...
Article
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The investigation was carried out to analyse the genetic polymorphism and gene expression of ATP1A1 gene in four different Indian goat breeds by using high resolution melting (HRM) and real time-PCR. ATPase is electro-genic ion pump which is maintains the balance of sodium and potassium ions in animal cells. The transport of Na+& K+ is variable at...
Article
Full-text available
Background: The aim of the present study was to isolate and characterize nontuberculous mycobacteria (NTM) on Lowenstein-Jensen media supplemented with glycerol or pyruvate on two different temperatures from soil samples from leprosy endemic tribal areas of Purulia. Methods: Mycobacterium leprae DNA was isolated from these samples followed by po...
Article
Full-text available
Immunomodulatory activity of hot aqueous extract of Neolamarckia cadamba leaves with particular reference to splenocyte proliferation and induction of cytokines has been investigated using Wistar albino rat model. Study of hot aqueous extract (HAE) of N. cadamba leaves over cell mediated immune response was carried out using six groups (Gp-I as con...
Article
Full-text available
Epilepsy is one of the most common neurological disorders and there is a pressing need to explore therapeutics based on Complementary and Integrative system of medicines. The present study was designed to validate the protective action of a homeopathic medicine Nux vomica on mice in experimental epilepsy, and also to elucidate its probable mechanis...
Article
Full-text available
Tuberculosis meningitis (TBM) is the most common form of chronic infection of central nervous system. Regardless of the extent of the problem, the general diagnostic outlook is discouraging specifically; there is no generally accepted early confirmative diagnostic protocol available for TBM. In the current work, 16 Cerebrospinal Fluid (CSF) cases w...
Article
Full-text available
Background: Plant extracts contains multiple active constituents which leads to the production of new drugs from plants and chemicals derived from various parts of plants. The objective of present study was to investigate the GC-MS analysis and antibacterial activity of L. inermis leaves extracts. Material and Methods: Crude methanol extract and it...
Article
Full-text available
The genetic variation in physiological response was analysed at population level in Jamunapari goats. The temperature humidity index (THI) range varied from 82.00 to 92.08 during hot period, 49.96 to 59.68 during cold period and 65.32 to 74.00 during thermo-neutral period. Physiological responses were recorded for 695, 617 and 291 animals during th...
Article
Full-text available
Introduction Nanotechnology is a branch of nanosciences which includes the manipulation of particles at their atomic level in order to obtain certain desirable properties that enhance their use in the treatment of various metabolic disorders as well as other life-threatening diseases including cancer. Photosynthesized nanoparticles are eco-friendly...
Article
Full-text available
Neolamarckia cadamba (Roxb.) Bosser syn. Anthocephalus cadamba (Roxb.) Miq., an evergreen tropical tree, known in Hindu Mythology, for its various medical properties. In the present study, immunomodulatory potential of N. cadamba has been investigated in Wistar albino rat model. The effect of hot aqueous extract (HAE) of N. cadamba leaves over diff...
Article
Full-text available
Objective:To investigate the antiepileptic effect of homeopathic remedy Nux vomica on mice and its comparison with standard therapeutic diazepam. Methods: BALB-c mice were taken and divided into three groups comprising ten mice in each group.The first group was treated as control; the second group received standard therapeutics (diazepam, i.p.) and...
Article
Full-text available
The present study was undertaken to assess the effect of different chemical activators along with 6-DMAP on in vitro matured caprine oocytes. From 4332 ovaries, 14235 cumulus oocyte complexes (COCs) were collected which were matured in TCM-199 medium containing follicle stimulating hormone (FSH) (5 µg/ml), Leutinizing hormone (LH) (10 µg/ml), oestr...
Article
Full-text available
Epilepsy is one of the most common neurological disorders and there is a pressing need to explore therapeutics based on Complementary and Integrative system of medicines. The present study was designed to validate the protective action of a homeopathic medicine Nux vomica on mice in experimental epilepsy, and also to elucidate its probable mechanis...
Article
Full-text available
Present study was carried out to test the efficacy of hot whole plant aqueous extract (HAE) of Solanum xanthocarpum Schrad and Wendl fam. Solanaceae against some gram positive and gram negative bacteria and its antioxidant activity. Hot whole plant aqueous extract (HAE) showed the significant(p>.01) antibacterial activity against the Bacillus subti...
Article
Full-text available
Paratuberculosis (pTB) is a chronic granulomatous enteritis caused by Mycobacterium avium subsp. paratuberculosis (MAP) in a wide variety of domestic and wild animals. Control of pTB is difficult due to the lack of sensitive, efficacious and cost-effective diagnostics and marker vaccines. Microscopy, culture, and PCR have been used for the screenin...
Article
Full-text available
Hot aqueous extract (HAE) of leaves of Anthocephalus cadamba (Roxb.) Miq, Rubiaceae has been screened for antimicrobial and antioxidant activity. Leaf extract was tested against some gram positive, gram negative and certain fungal strains. Leaf extract showed significant (p < .01) antibacterial and antifungal activity against Staphylococcus aureus,...
Article
Full-text available
This work has been performed to study the efficacy of hot whole plant aqueous extract of Solanum xanthocarpum Schrad and Wendl on hematological and Biochemical parameters of wistar albino rats.Doses hot aqueous extract of different concentration like 125 mg/kg, 250 mg/kg, 500 mg/kg and 1000 mg/kg body weight was given orally to different group of r...
Article
Full-text available
Plants play a major role on the earth and human beings depend on plants because of their medicinal properties. About 80% of the world population using plants as a medicinal drugs because plants have no side effects and show synergistic effect unlike modern medicine. In the present study, review and authentication of the various aspects of the plant...
Article
Full-text available
Human Papilloma Virus (HPV) infection is transmitted primarily via sexual and affects mostly basal epithelial cells of the skin or inner lining of tissues and are categorized as cutaneous types or mucosal types. It is known that HPV infection is strongly related to the development of cervical cancer, as viral DNA is detected in 99% of cervical canc...
Article
The present study was aimed to evaluate the immunomodulatory activities of hot aqueous extract of pods & leaves (HAEP & HAEL) of C. fistula in albino rats. HAEP/HAEL were given oral dose of 125, 250 & 500 mg/ kg to healthy rats divided into one unfed (control group) and six fed groups. The humoral immune response was carried out by testing antibody...
Article
Full-text available
Objectives: The present study was undertaken to unravel the newer marker phytoconstituents in methanolic extract of Moringa oleifera leaves (MOLE) and evaluation of its immunomodulatory and splenocytes proliferation potential in rats. Materials and methods: Hot methanolic extract of MOLE was subjected to gas chromatography-mass spectrometry (GC-...
Article
Full-text available
Mycobacterium avium subspecies paratuberculosis (MAP), the cause of granulomatous chronic enteritis in ruminants (Johne’s disease) is under reported due to difficulties in diagnosing pre-clinical cases. Compromised specificity is a problem due to extensive sharing of antigens /epitopes among MAP and other mycobacterial strains. Culture filtrate (CF...
Article
Full-text available
In the quest to achieve success in fighting infections, innumerous antibiotics have been overexploited leaded to drug resistance, forcing researchers to focus on ayurvedic medicines. C. fistula, a native of Indian subcontinent is distributed throughout SouthEast Asia, is used as a medicinal plant for treatment of pruritus, leucoderma, diabetes, hae...
Article
Full-text available
The present work has been designed to study the effect of hot aqueous leaf extract of Anthocephalus cadamba (Roxb.) Miq, Rubiaceae, on haematological and biochemical parameters of wistar albino rats. Different group of rats were administered orally with doses like 125mg/kg, 250mg/kg and 500mg/kg body weight of leaf extract. Treatment with different...
Conference Paper
Full-text available
C. fistula a medicinal plant has been used in the treatment of various ailments in different parts of the world since ancient time. Studies indicated that the different parts of these plants contain a broad spectrum of secondary metabolites. The qualitative and quantitative analysis of hot aqueous extract of pods and leaves (HAEP & HAEL) was carrie...
Article
Full-text available
The present study was undertaken to study the immuno modulatrory effects of leaves of Ocimum santum (OS) and Argemone mexiana (AM) plants in chicken model. 250 mg/kg body weight oral dose of OS and AM was found ideal and nontoxic in chickens and experimental chickens were fed this dose. Humoral immune response to S. enterica serovar Typhimurium 'O'...
Article
Full-text available
Ocimum sanctum is well known for its antimicrobial properties in Indian traditional medicinal system in Ayurveda. Different preparations of O. sanctum plants and parts of it have been reported throughout the world for its medicinal properties including antiviral effects. Thus in present study hot aqueous extract of O. sanctum leaves was used to stu...
Article
Full-text available
In the present study 220 stool samples collected from diarrheic children admitted to different hospitals and nursing homes of Uttar Pradesh and Uttarakhand were screened for rotavirus. Of 220 diarrheic samples screened 46 samples were found to be positive for rotavirus by RNA PAGE. All the isolates exhibited 4-2-3-2 migration pattern suggesting gro...
Chapter
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Algae like some other higher plants, produces stored lipids in the form of triacylglycerol (TAG). Comparatively algae produce more oil than any other biofuel technology which is currently being used. Micro-algal species can accumulate substantial quantity of lipid, sometimes even 50% of their biomass. Algae can inhabitant a wide variety of natural...
Conference Paper
Full-text available
Algae like some other higher plants, produces stored lipids in the form of triacylglycerol (TAG). Comparatively algae produce more oil than any other biofuel technology which is currently being used. Micro-algal species can accumulate substantial quantity of lipid, sometimes even 50% of their biomass. Algae can inhabitant a wide variety of natural...
Article
Full-text available
Neonatal diarrhoea is one of the most important conditions of calves, associated with morbidity and mortalities. Diarrhoeal diseases have an adverse effect on calf health status, survival and productive performances. Corona virus is one of the etiological agents responsible for calf diarrhea worldwide. However there is paucity of literature stating...
Article
Full-text available
Medicinal plants have long been used as a source of medicine all over the world in curing human as well as animals. There is an increasing need for substances with antiviral activity as there are less number of synthetic antiviral drugs available. The emergence of resistant virus strains as well as their various side effects due to their frequent u...
Chapter
Each and every process in the world is just based on the energy exchange in this universe. Energy is the key input that drives our life cycle in every manner. Primarily, it can be said as a gift to mankind from nature. With growing population, increasing industrialization in developing country, the global demand for energy is expected to increase b...
Article
Full-text available
Diarrhoeal diseases are important cause of morbidity and mortality in neonates of various animal species. Rotaviruses cause neonatal diarrhea in calves. The present study was carried out to determine the prevalence of rotavirus infection among cow calves in Mathura and adjacent regions. During the present study 101 diarrheic and 29 non diarrheic st...
Article
Full-text available
Diarrhoeal diseases are important cause of morbidity and mortality in neonates of various animal species. Rotaviruses cause neonatal diarrhea in calves. The present study was carried out to determine the prevalence of rotavirus infection among cow calves in Mathura and adjacent regions. During the present study 101 diarrheic and 29 non diarrheic st...
Article
Full-text available
Objective: To investigate the protective role of Ocimum sanctum (O. sanctum) leaves against Salmonella typhimurium(S. typhimurium) infection in rats by inducing TNF-alpha, IFN-gamma & IL-2 cytokines. Methods: Wistar albino rats were fed with aqueous extract of O. sanctum leaves using 250 mg/kg body weight dose once a day for 20 consecutive days. Co...
Article
Full-text available
Ocimum sanctum, a well known herb in Indian medicine, possesses various therapeutic properties including healing properties and cytokine induction. Wound healing activity of cold aqueous extract of O. sanctum leaves along with its effect on tumor necrosis factor-alpha (TNF-alpha) was assessed using excision model of wound repair in Wistar albino ra...
Article
Full-text available
Objective: To investigate the regulatory effect of aqueous extract of leaves of Ocimum sanctum on IL-2 cytokine production in vivo and in vitro, and the effect of leaves extract on general blood picture including T& B lymphocytes. Methods: For in vivo studies albino Wistar rats were treated with aqueous crude leaves extract of Ocimum sanctum for 20...
Article
Full-text available
Ocimum sanctum (family-Labiatae) is the most sacred plant in India. Since ancient time it has been used by Ayurvedic practioners and laypersons for many health ailments and it has both medicinal and spiritual significance in Ayurveda. The effect of oral treatment with aqueous leaves extract of Ocimum sanctum on immune responses, concanavalin-A (Con...
Article
A new, specific, sensitive, selective, precise, and reproducible high-performance thin-layer chromatographic (HPTLC) method has been established for study of the stability of 3-acetyl-11-keto-β-boswellic acid (AKBA). HPTLC was performed on aluminium foil plates coated with 200 μm silica gel 60F254. Linear ascending development with toluene-ethyl ac...

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