Anita Rogowicz-Frontczak

Anita Rogowicz-Frontczak
Poznan University of Medical Sciences · Department of Diabetology

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25
Publications
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260
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Publications

Publications (25)
Article
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Introduction Carbohydrates are one of the macronutrients which have the most substantial influence on glycemic response. The cooling of rice after cooking causes retrogradation of starch, which becomes a non-absorbable product in the human digestive tract. Aim of the study This study aimed to assess whether cooling of rice affects postprandial gly...
Article
Context: Higher prevalence of polycystic ovary syndrome (PCOS) in women with type 1 diabetes (T1DM) is linked to exogenous insulin, especially when diabetes is diagnosed before puberty. Objective: The study evaluates the impact of prepubertal onset of T1DM and insulin therapy on PCOS diagnosis and phenotypic characteristics in women with T1DM....
Article
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Background Type 1 diabetes (T1DM) often coexists with other autoimmune diseases, most commonly with hypothyroidism. To date, the influence of coexisting autoimmune hypothyroidism (AHT) on the course of chronic neurovascular complications of autoimmune diabetes has not been established. The aim of the study was to assess the relationship between AHT...
Article
Aim Type 1 diabetes mellitus (T1DM) is a disease characterized by an absolute deficiency of endogenous insulin secretion. Insulin resistance (IR) may develop among patients with T1DM. Vitamin D deficiency was reported to be a risk factor in the development of IR. The aim of the study was to assess the relationship between serum concentrations of 25...
Article
Aim The study aimed to assess the prevalence of zinc transporter 8 autoantibodies (ZnT8-ab), other diabetes-related autoantibodies and clinical manifestation of type 1 diabetes in adults, depending on age of the onset of disease. Methods 119 patients with type 1 diabetes, 66 at age <35 years (T1DM < 35) and 53 T1DM at age ≥35 years (T1DM ≥ 35). We...
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Introduction: Whether menopause increases the risk of type 2 diabetes mellitus (T2DM) independently of ageing has been a matter of debate. Controversy also exists about the benefits and risks of menopausal hormone therapy (MHT) in women with T2DM. Aims: To summarise the evidence on 1) the effect of menopause on metabolic parameters and the risk of...
Article
Full-text available
Purpose: Type 1 diabetes mellitus (T1DM) is a disorder of insulin deficiency but with a wide range of hormones simultaneously disturbed. The study was performed to explore relation of free triiodothyronine (FT3) with metabolic control and occurrence of microangiopathic complications. Methods: A total of 266 adult T1DM participants [56% men; 32 (...
Article
Full-text available
To investigate the effect of insulin resistance (IR) on thyroid function, thyroid autoimmunity (AIT) and thyroid volume in type 1 diabetes (T1DM). 100 consecutive patients with T1DM aged 29 (±6) years with diabetes duration 13 (±6) years were included. Exclusion criteria were: history of thyroid disease, current treatment with L-thyroxin or anti-th...
Article
Full-text available
AimsTo assess the prevalence of ZnT8-ab and its correlation to other autoimmune markers and diabetic ketoacidosis occurrence in children and adults with T1DM onset. Methods The study included 367 patients (218 children; 149 adults) at the T1DM onset. Selected diabetes-related autoantibodies such as GAD-ab, IA2-ab, ZnT8-ab were tested before the ini...
Article
Changes in sensitivity to insulin occur in the course of a number of endocrine disorders. Most of the hormones through their antagonistic action to insulin lead to increased hepatic glucose output and its decreased utilisation in peripheral tissues. Carbohydrate disorders observed in endocrine diseases result from the phenomenon of insulin resistan...
Article
Full-text available
Autoimmune Addison’s disease (AAD) associates with exceptional susceptibility to develop other autoimmune conditions, including type 1 diabetes (T1D), marked by positive serum autoantibodies to insulin (IAA), glutamic acid decarboxylase (GADA) and insulinoma-associated protein 2 (IA-2A). Zinc transporter 8 (ZnT8) is a new T1D autoantigen, encoded b...
Article
Background: Larger thyroid volume and nodular thyroid disease were found to be associated with insulin resistance (IR) in patients with type 2 diabetes (T2DM). Similar analyses is lacking in T1DM. Aims: To check the association between thyroid volume and IR using estimated glucose disposal rate (eGDR) in patients T1DM. Materials and methods: We inc...
Article
Introduction: Influence of vitamin D status on metabolic control of type 1 diabetes (T1DM) remains controversial. The marker of long-term metabolic control that was not evaluated in this context is tissue accumulation of advanced glycation endproducts (AGEs), measured using skin autofluorescence. Aim of the study was to determine the association be...
Article
Introduction: Type 1 diabetes (T1DM) is often associated with autoimmune thyroid disease (AITD). Common susceptibility genes increase risk for development of both AITD and T1DM. The influence of this comorbidity on the risk of diabetic microangiopathy is unknown. Methods/design: We included 100 consecutive patients with T1DM (55 men, and 45 women)...
Article
Full-text available
The diagnosis of autoimmune diabetes in non-obese adults is based on detection of autoantibodies to glutamic acid decarboxylase autoantibodies (GADA), islet cells antibodies (ICA), antibodies to tyrosine phosphatase (IA-2A). Zinc transporter 8 (ZnT8) was identified as a new auto-antigen in diabetes type 1. The coincidence of autoimmune thyroiditis...
Article
The association of inflammation with cardiovascular (CV) complication in diabetes is still a matter of considerable debate. Arterial stiffness and enhanced wave reflection play an important role in CV complication. Therefore we address the question whether markers of inflammation are correlated with parameters of wave reflection in type 1 diabetes....
Article
Full-text available
Introduction: The degeneration of retinal neurons and glial cells has recently been postulated in the pathogenesis of diabetic retinopathy. Optical coherence tomography (OCT) allows to perform qualitative and quantitative measurements of retinal thickness (RT) with identification of individual retinal layers. Objectives: We compared RT, retinal...
Article
Full-text available
The aim of the study was to assess carotid intima-media thickness (CIMT) as a subclinical marker of atherosclerosis and arterial stiffness in type 1 diabetic patients in relation to microangiopathy. We included 87 type 1 diabetic patients (44 women, 43 men), median age 34 years (interquartile range [IQR] 29-43), median disease duration 10 years (IQ...
Article
Aim: Classification of diabetes type in adults patients remains difficult. This study was undertaken to determine the relationship between presence of autoantibodies in the serum and the result of glucagon stimulation test in non obese patients at aged above 35 years with newly diagnosed diabetes. Material and methods: Study involved 52 non obese...
Article
Full-text available
The aim of the study was to assess the relationships between diabetic retinopathy, subclinical atherosclerosis and wave reflection in type 1 diabetic patients. The investigation involved 87 type 1 diabetic patients aged 34 years (interquartile range [IQR]: 29-43), with a disease duration of 10 years (IQR: 9-14). Of these 39 (45%) had diabetic retin...
Article
The aim of the study was to assess the factors that influence carotid intima-media thickness (CIMT) and arterial stiffness in type 1 diabetic patients. We included 87 type 1 diabetic patients (44 women, 43 men), median age 34 years, disease duration 10 years, HbA1c 8.2%. CIMT was measured using high resolution ultrasonography. Arterial stiffness wa...

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