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Publications (18)
The scientific community recognizes that molecular xenomonitoring (MX) can allow infected mosquitoes to serve as a proxy for human infection in vector-borne disease surveillance, but developing reliable MX systems for programmatic use has been challenging. The primary aim of this article is to examine the available evidence to recommend how MX can...
Background: The Recife Metropolitan Region (RMR), north-eastern Brazil, was the epicentre of the 2015 Zika virus (ZIKV) epidemic, which was followed by a 2016 chikungunya virus (CHIKV) epidemic. It historically has amongst the highest incidence of dengue virus (DENV) infections and is the only remaining focus of lymphatic filariasis (LF) in Brazil....
Introduction
Molecular xenomonitoring (MX)—pathogen detection in the mosquito rather than human—is a promising tool for lymphatic filariasis (LF) surveillance. In the Recife Metropolitan Region (RMR), the last LF focus in Brazil, Culex quinquefasciatus mosquitoes have been implicated in transmitting Wuchereria bancrofti parasites. This paper presen...
Screening of adult C. quinquefasciatus for W. bancrofti.
(DOCX)
Handheld aspirator, CDC light trap, and field deployment.
Figure S1. [A] Handheld Aspirator Used in CMC and MMRR; [B] CDC Light Trap Used in CMC; [C] Field Deployment of Handheld Aspirator.
(DOCX)
Pre-field laboratory marking experiments.
(DOCX)
Recognition of the need for evidence-based interventions to help to improve the effectiveness and efficiency of humanitarian responses has been increasing. However, little is known about the breadth and quality of evidence on health interventions in humanitarian crises. We describe the findings of a systematic review with the aim of examining the q...
Dengue cases have increased in younger age groups in Brazil. Maternal anti-dengue antibodies can have a protective effect in the first months of life, but their decline can increase the risk of severe dengue. A prospective birth cohort was established in 2011-2012 in the city of Recife, Pernambuco State, Brazil, to determine the incidence of seroty...
To assess the extent to which climate may affect the abundance of Musca sorbens, a putative vector of trachoma.
Studies were identified by systematically searching online databases including CAB abstracts, Embase, Global Health, Medline, Web of Science and BIOS Online, references from key articles, and the websites of relevant international agenc...
Background:
The need for a stronger scientific evidence base for responses to humanitarian crises has been identified by various public health actors. To this end, the UK Department for International Development (DFID) and the Wellcome Trust commissioned a study to review the evidence base of public health interventions in humanitarian crises. The...
Water, sanitation, and hygiene (WASH) interventions are amongst the most crucial in humanitarian crises, although the impact of the different WASH interventions on health outcomes remains unclear.
To examine the quantity and quality of evidence on WASH interventions on health outcomes in humanitarian crises, as well as evaluate current evidence o...
The need for a stronger scientific evidence base to inform the response to humanitarian crises has been identified by various public health actors. This project was commissioned in order to review the evidence base for public health interventions in humanitarian crises. The project provided a rigorous assessment of the quality and depth of the curr...
Trachoma is the most common cause of infectious blindness. Hot, dry climates, dust and water scarcity are thought to be associated with the distribution of trachoma but the evidence is unclear. The aim of this study was to evaluate the epidemiological evidence regarding the extent to which climatic factors explain the current prevalence, distributi...
As part of a 3-year demonstration project to improve pneumococcal polysaccharide vaccine (PPV) coverage among older adults, the Minnesota Department of Health conducted a baseline evaluation of knowledge, attitudes, and beliefs among the general public regarding PPV.
A random-digit dialing telephone survey was conducted among community-dwelling adu...
Pneumonia and influenza together are the sixth-leading cause of death in this country. Physicians have the tools and influence to prevent many of these deaths and significantly improve their patients' health and quality of life. There is no reason for these tools to be underused.