Anirban Dutta

Anirban Dutta
University at Buffalo, The State University of New York | SUNY Buffalo · Department of Biomedical Engineering

Ph.D.

About

214
Publications
41,348
Reads
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1,625
Citations
Introduction
Anirban Dutta currently works at the Department of Biomedical Engineering, University at Buffalo, The State University of New York. Anirban does research in Bioengineering, Mechanical Engineering and Instrumentation Engineering.
Additional affiliations
October 2020 - February 2022
University at Buffalo, The State University of New York
Position
  • Associate Professor of Research
Description
  • Director of Neuroengineering and Informatics for Rehabilitation laboratory.
August 2016 - September 2020
University at Buffalo, The State University of New York
Position
  • Professor (Assistant)
Description
  • Director of Neuroengineering and Informatics for Rehabilitation laboratory.
January 2016 - November 2020
Leibniz Research Center for Working Enviroment and Human Factors
Position
  • Researcher
Description
  • Development of computational and hardware tools to facilitate patient-specific non-invasive electrical brain stimulation.

Publications

Publications (214)
Poster
Full-text available
Motor skills that involve bimanual motor coordination need a high level of training to be performed effectively. Transcranial electrical stimulation has the potential to enhance performance and reduce errors for bimanual motor tasks. In the current study, we performed transcranial direct current stimulation (tDCS) with functional near-infrared spec...
Poster
Full-text available
Introduction: • Traumatic Brain Injury (TBI), described as the most complex disease in the most complex organ [1], is a pressing but unsolved public health problem at a global level. • Worldwide 50 million TBI occur each year costing USD400 billion to the society [2]. • Despite being a leading cause of mortality and disability in young adults world...
Preprint
Fundamentals of Laparoscopic Surgery (FLS) is a training module designed to provide basic surgical skills. During skill training of the FLS "suturing and intracorporeal knot-tying" task – the most difficult among the five psychomotor FLS tasks, learning from errors is one of the basic principles of motor skill acquisition where appropriate contextu...
Preprint
Fundamentals of Laparoscopic Surgery (FLS) is a standard education and training module with a set of basic surgical skills. During surgical skill acquisition, novices need to learn from errors due to perturbations in their performance which is one of the basic principles of motor skill acquisition. This study on thirteen healthy novice medical stud...
Preprint
The physiological origin of the aperiodic signal present in the electrophysiological recordings, called 1/f neural noise, is unknown; nevertheless, it has been associated with health and disease. The power spectrum slope, -a in 1/f a , has been postulated to be related to the dynamic balance between excitation (E) and inhibition (I). Our study foun...
Preprint
The Fundamentals of Laparoscopic Surgery (FLS) training module is designed to provide essential surgical skills. During skill training of the FLS "suturing and intracorporeal knot-tying" task (FLS complex task) – the most difficult among the five psychomotor FLS tasks, the error-related chain of mental processes is postulated to depend on the skill...
Article
Full-text available
Background: Maladaptive neuroplasticity-related learned response in substance use disorder (SUD) can be ameliorated using noninvasive brain stimulation (NIBS); however, inter-individual variability needs to be addressed for clinical translation. Objective: Our first objective was to develop a hypothesis for NIBS for learned response in SUD based...
Preprint
Transcranial electrical stimulation (tES) can exert cerebrovascular effects, but the mechanisms are unclear. Long-term (≥3min) transcranial direct current stimulation (tDCS) can also change the extracellular ion concentrations that can modulate neuronal excitability. An increase in interstitial K+ can modulate the neurovascular system's sensitivity...
Chapter
Intermittent claudication in peripheral arterial disease (PAD) may be monitored with near-infrared spectroscopy (NIRS) of an exercising muscle and skin; however, skin NIRS data in conjunction with electromyography (EMG) of muscle activation has not been investigated. This paper presents the development of a wearable skin NIRS sensor to determine th...
Chapter
Transcranial direct current stimulation (tDCS) has been a popular way of modulating brain activity in a non-invasive manner and has shown to affect neural plasticity and cerebrovascular response in humans. It is important to analyze how transcranial direct current stimulation-generated electric fields can induce effects on hemodynamic response. The...
Chapter
Electroencephalogram (EEG) source localization is used to estimate regions of ictal onset in epilepsy patients with temporal lobe epilepsy. Localization of EEG data struggles to achieve high spatial resolution, especially in deep brain regions, and is difficult to validate. In this paper we generate simulated EEG data using a spatiotemporally reali...
Chapter
Early-onset neonatal sepsis can increase the risk of hypoxic-ischemic encephalopathy (HIE) that can worsen the patient’s prognosis. We investigated neurometabolic coupling (NMC) in five full-term neonates with HIE and sepsis that was found lower than the other five with HIE only. We hypothesized that transcranial photobiomodulation might upregulate...
Chapter
Transcranial direct current stimulation (tDCS) can modulate corticomuscular coherence and reaction time of the targeted muscle during a single-muscle ballistic myoelectric control where anodal tDCS of the primary motor cortex (M1) leg representation decreased the reaction time while the cerebellar tDCS (ctDCS) increased the same. In this study, we...
Preprint
Full-text available
Background: Maladaptive neuroplasticity related learned response in substance use disorder (SUD) can be ameliorated using non-invasive brain stimulation (NIBS); however, inter-individual variability needs to be addressed for clinical translation. Objective: Our first objective was to develop a hypothesis for NIBS for learned response in SUD based o...
Article
Full-text available
Objective Obesity and physical activity are two major factors affecting aerobic performance in older adults. The underlying mechanisms of the causes are still unknown. Oxidative capacity, muscles’ maximal capacity to utilize oxygen, is a part of aerobic performance. Muscle oxygen level (SmO2), a measure of oxidative capacity, reflects the balance b...
Article
Full-text available
Feasibility of portable neuroimaging of cerebellar transcranial direct current stimulation (ctDCS) effects on the cerebral cortex has not been investigated vis-à-vis cerebellar lobular electric field strength. We studied functional near-infrared spectroscopy (fNIRS) in conjunction with electroencephalography (EEG) to measure changes in the brain ac...
Conference Paper
Chronic venous insufficiency (CVI) can lead to blood clotting in the deep veins of the legs, a disease known as deep vein thrombosis. An estimated 40 percent of people in the United States have venous insufficiency that may be ameliorated with neuromuscular electrical stimulation (NMES). Near-infrared spectroscopy (NIRS) is a non-invasive optical i...
Conference Paper
Full-text available
this study investigates the difference in effective connectivity among novice medical students trained on physical and virtual simulators to perform the Fundamental laparoscopic surgery (FLS) pattern cutting task (PC). We propose using dynamic spectral Granger causality (GC) in the frequency band of [0.01-0.07]Hz to measure the effect of surgical t...
Conference Paper
Fundamentals of Laparoscopic Surgery (FLS) is a prerequisite for board certification in general surgery in the USA. In FLS, the suturing task with intracorporeal knot tying is considered the most complex task. Transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (PFC) has been shown to facilitate FLS surgical skill a...
Article
Full-text available
Neurological disorder such as stroke can adversely affect one’s weight-bearing symmetry leading to dysfunctional postural control. Recovery after stroke is facilitated through functionally-relevant neuroplastic modulation. Functionally-relevant cerebellum coordinates voluntary movements. Specifically, the dentate nuclei and lower limb representatio...
Article
Full-text available
Transcranial direct current stimulation (tDCS) has been shown to evoke hemodynamics response; however, the mechanisms have not been investigated systematically using systems biology approaches. Our study presents a grey-box linear model that was developed from a physiologically detailed multi-compartmental neurovascular unit model consisting of the...
Poster
Full-text available
Functional brain connectivity (FC) using functional near-infrared spectroscopy (fNIRS) during a fundamental laparoscopic surgery (FLS) pattern cutting (PC) task was investigated in physical and virtual simulators. FC was based on wavelet coherence and wavelet phase coherence from oxygenated hemoglobin concentration changes. Coefficient of variation...
Preprint
Full-text available
Despite substantial progress towards establishing virtual reality (VR) simulators as a replacement for physical ones for skill training, its effect on the brain network during skill acquisition has not been well addressed. In this study, we employed portable optical neuroimaging technology and Granger causality approach to uncover the impact of the...
Chapter
Functional brain connectivity using functional near-infrared spectroscopy (fNIRS) during a pattern cutting (PC) task was investigated in physical and virtual simulators. 14 right-handed novice medical students were recruited and divided into separate cohorts for physical (N = 8) and virtual (N = 6) PC training. Functional brain connectivity measure...
Preprint
The comparison of the effects of physical and virtual reality (VR) simulators on the brain network during skill acquisition has not been well addressed. In this study, the brain network and skilled behavior relationship were evaluated using functional near-infrared spectroscopy (fNIRS) data from seven experienced right-handed surgeons and six right...
Poster
Full-text available
Fundamentals of Laparoscopic Surgery (FLS) is a prerequisite for board certification in general surgery in the USA. It includes a motor skills portion with five psychomotor tasks of increasing task complexity: (i) pegboard transfers, (ii) pattern cutting, (iii) placement of a ligating loop, (iv) suturing with extracorporeal knot tying, and (v) sutu...
Article
Full-text available
Surgical skill acquisition may be facilitated with a safe application of transcranial direct current stimulation (tDCS). A preliminary meta-analysis of randomized control trials showed that tDCS was associated with significantly better improvement in surgical performance than the sham control; however, meta-analysis does not address the mechanistic...
Preprint
Full-text available
Fundamentals of Laparoscopic Surgery (FLS) is a prerequisite for board certification in general surgery in the USA. It includes a motor skills portion with five psychomotor tasks of increasing task complexity: (i) pegboard transfers, (ii) pattern cutting, (iii) placement of a ligating loop, (iv) suturing with extracorporeal knot tying, and (v) sutu...
Preprint
Full-text available
Chronic venous insufficiency (CVI) can lead to blood clotting in the deep veins of the legs, a disease known as deep vein thrombosis. An estimated 40 percent of people in the United States have venous insufficiency that may be ameliorated with functional electrical stimulation (FES). Near-infrared spectroscopy (NIRS) is a non-invasive optical imagi...
Preprint
Full-text available
Fundamentals of Laparoscopic Surgery (FLS) is a prerequisite for board certification in general surgery in the USA. In FLS, the suturing task with intracorporeal knot tying is considered the most complex. Transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (PFC) has been shown to facilitate FLS surgical skill acquis...
Preprint
Full-text available
Functional brain connectivity using functional near-infrared spectroscopy (fNIRS) during a pattern cutting (PC) task was investigated in physical and virtual simulators. 14 right-handed novice medical students were recruited and divided into separate cohorts for physical (N=8) and virtual (N=6) PC training. Functional brain connectivity measured we...
Article
Significance: Surgical simulators, both virtual and physical, are increasingly used as training tools for teaching and assessing surgical technical skills. However, the metrics used for assessment in these simulation environments are often subjective and inconsistent. Aim: We propose functional activation metrics, derived from brain imaging measure...
Article
Full-text available
Acquisition of fine motor skills is a time-consuming process as it is based on learning via frequent repetitions. Transcranial electrical stimulation (tES) is a promising means of enhancing simple motor skill development via neuromodulatory mechanisms. Here, we report that non-invasive neurostimulation facilitates the learning of complex fine biman...
Article
Full-text available
Background Investigation of lobule-specific electric field effects of cerebellar transcranial direct current stimulation (ctDCS) on overground gait performance has not been performed, so this study aimed to investigate the feasibility of two lobule-specific bilateral ctDCS montages to facilitate overground walking in chronic stroke. Methods Ten ch...
Patent
Full-text available
System and methods for stimulating the neurovascular system of the cerebral tissue through optimally placed devices , while simultaneously measuring the evoked neuronal and hemodynamic responses , also using optimally placed devices , is disclosed. Systems and methods for iteratively stimulating the neurovascular system and recording neuronal and h...
Preprint
Full-text available
Cannabis is the most widely cultivated, trafficked and abused illicit drug (“WHO | Cannabis,” n.d.; “World Drug Report 2020,” n.d.). In 2018, an estimated 192 million people aged 15-64 years used cannabis for nonmedical purposes globally (Degenhardt et al., 2013). The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated...
Article
Full-text available
Homeostatic control of neuronal excitability by modulation of synaptic inhibition (I) and excitation (E) of the principal neurons is important during brain maturation. The fundamental features of in-utero brain development, including local synaptic E–I ratio and bioenergetics, can be modeled by cerebral organoids (CO) that have exhibited highly reg...
Preprint
Full-text available
Acquisition of fine motor skills is a time-consuming process as it requires frequent repetitions. Transcranial electrical stimulation is a promising means of enhancing simple motor skill development via neuromodulatory mechanisms. Here, we report that non-invasive neurostimulation facilitates the learning of complex fine bimanual motor skills assoc...
Preprint
Full-text available
Transcranial direct current stimulation (tDCS) has been shown to evoke hemodynamics response; however, the mechanisms have not been investigated systematically using systems biology approaches. We postulate that such a mechanistic understanding of the hemodynamics response, called cerebrovascular reactivity (CVR) to tDCS, can facilitate adequate de...
Preprint
Full-text available
Transcranial direct current stimulation (tDCS) has been shown to evoke hemodynamics response; however, the mechanisms have not been investigated systematically using systems biology approaches. We postulate that such a mechanistic understanding of the hemodynamics response, called cerebrovascular reactivity (CVR) to tDCS, can facilitate adequate de...
Preprint
Full-text available
The mechanism of action for the cerebral vasculature hemodynamic response to the electric field effects during transcranial direct current stimulation (tDCS) has been less explored. We postulate that such a mechanistic understanding of the cerebrovascular reactivity (CVR) to tDCS can facilitate adequate tDCS dosing to facilitate cognitive rehabilit...
Preprint
Full-text available
Background Stroke often results in impaired gait, which can limit community ambulation and the quality of life. Recent works have shown the feasibility of transcranial Direct Current Stimulation (tDCS) as an adjuvant treatment to facilitate gait rehabilitation. Since the cerebellum plays an essential role in balance and movement coordination, which...
Preprint
Full-text available
Background: Cerebellar transcranial Direct Current Stimulation (ctDCS) has been shown to be promising as an adjuvant treatment to facilitate post-stroke gait rehabilitation; however, investigation of lobule-specific electric field effects on overground gait performance has not been performed. Methods: Ten chronic post-stroke male subjects participa...
Preprint
Full-text available
Background: Investigation of lobule-specific electric field effects of cerebellar transcranial direct current stimulation (ctDCS) on overground gait performance has not been performed, so this study aimed to investigate the feasibility of two lobule-specific bilateral ctDCS montages to facilitate overground walking in chronic stroke. Methods: Ten c...
Preprint
Full-text available
Stroke often results in impaired gait, which can limit community ambulation and the quality of life. Recent works have shown the feasibility of transcranial Direct Current Stimulation (tDCS) as an adjuvant treatment to facilitate gait rehabilitation. Since the cerebellum plays an essential role in balance and movement coordination, which is crucial...
Preprint
Full-text available
Homeostatic control of neuronal excitability by modulation of synaptic inhibition (I) and excitation (E) of the principal neurons is important during brain maturation. The fundamental features of in utero brain developmental, including local synaptic E-I ratio and bioenergetics, can be modeled by cerebral organoids (CO) that have exhibited highly r...
Preprint
Full-text available
Cerebellar transcranial direct current stimulation (ctDCS) can facilitate motor learning; however, ctDCS effects have not been investigated using portable neuroimaging vis-a-vis lobular electric field strength. This is important since the subject-specific residual architecture for cerebellar interconnections with the cerebral cortex, including the...
Article
Full-text available
Coronavirus disease (COVID-19) has been declared as a pandemic by the World Health Organization (WHO).[...]
Article
Background Neurovascular-based imaging techniques such as functional MRI (fMRI) may reveal signs of consciousness in clinically unresponsive patients but are often subject to logistical challenges in the intensive care unit (ICU). Near-infrared spectroscopy (NIRS) is another neurovascular imaging technique but low cost, can be performed serially at...
Article
Full-text available
Brain–Computer Interfaces (BCI) have witnessed significant research and development in the last 20 years where the main aim was to improve their accuracy and increase their information transfer rates (ITRs), while still making them portable and easy to use by a broad range of users [...]
Article
Background It is poorly understood how public perception of the difference between brain death and circulatory death may influence attitudes towards organ donation. We investigated the public opinion on brain death versus circulatory death and documented inconsistencies in the legislations of countries with different cultural and socioeconomic back...
Poster
Full-text available
Dementia is a major emerging public health burden in the developing world. Prevalence of dementia in India: 0. 84%- 6.7% & its prevalence of 3.7 million reported in 2010 is expected to double by 2030, and treble by 2050. (1) Most Dementias are missed at early treatable stage: 1. Low doctor - patient ratio 2. Paper-and-pencil-tasks required for diag...
Article
Full-text available
Objective: Cerebrovascular accidents are the second leading cause of death and the third leading cause of disability worldwide. We hypothesized that cerebellar transcranial direct current stimulation (ctDCS) of the dentate nuclei and the lower-limb representations in the cerebellum can improve functional reach during standing balance in chronic (>...
Chapter
Mothers, fathers, and family and community members eagerly await the birth of a newborn baby the world over. Nearly 260 babies were born every minute in 2017, approximately 135 million births in total for the year. Although often a time of great joy for families, the first month of life is the most vulnerable of a child’s life, with an estimated 2....
Article
Objective: Aging is associated with a decline in cognitive and motor performances, which are a part of geriatric syndromes. Since aging is associated with morphological changes in the cerebellum and cerebellar morphology is a good predictor of cognitive and motor performances, so the study of cerebellar role in age-related decline in performance i...