Anil Kumar Verma

• PhD
• Professor at Dr. Yashwant Singh Parmar University of Horticulture and Forestry

Honey is a sweet natural product produced by honey bees (Apis spp), which gather nectar from flowers before converting it to nutritious food. Due to the variation of botanical origin, honey differs in appearance, sensory perception and composition. It is a natural biological product that contained simple sugars mainly glucose and fructose (70–80%),...

Background Plasmodium falciparum is the main cause of malaria in North-Eastern (NE) states of India. Artemether–lumefantrine (AL) was introduced as first-line therapy against uncomplicated P. falciparum cases in 2013 after the emergence of resistance to sulfadoxine–pyrimethamine. The aim of the study was to assess the therapeutic efficacy of AL and...

Rapid diagnostic tests (RDTs) are crucial for diagnosing malaria in resource-limited settings. These tests, which detect the histidine-rich protein 2 (PfHRP2) and its structural homologue PfHRP3, are specifically designed to identify Plasmodium falciparum. Deletion of the Pfhrp2 gene in parasite has been reported in India and other malaria-endemic...

The quest for healthier beverage options has led to the development of low-calorie alternatives to conventional sugary drinks. This study focused on the use of ultrasonication-enzymatic extraction to produce a low-calorie ready-to-drink Kangra orthodox black tea with the natural sweetener Stevia rebaudiana. By employing sonication time (9 to 45 min...

Spray drying, which is a cost-effective dehydration method in the food industry, excels at preserving product integrity. Still, it has problems like losing quality because of heat, not being able to control particle sizes as well as it could, wasting energy, and nozzle blockages that make bioactive compounds like vitamin C, carotenoids, flavanols,...

The central goal of this investigation is to optimize static brewing using response surface methodology for the preparation of static brew ready-to-drink Kangra orthodox green tea, while enhancing flavour and quality while incorporating selected sweeteners to satisfy consumer preferences and market requirements. In this study, the concentration of...

The presentation was discussed on new novel material for future in energy devices application.

Consumer awareness of the health benefits of omega‐3 fatty acids is driving the increasing consumption of food fortified with essential fatty acids. Food fortification has been identified as the workable strategy by the WHO and FAO to decrease the incidence of nutrient deficiencies at the global level and fruit/s cereal‐based bars are one of the mo...

Background: Diabetic foot ulcers (DFU) are one of the major complications of diabetes. Despite proper insulin treatment and a strict diabetic diet, 15% of diabetic population develop non-healing ulcers which leads to amputation of the lower limb. Wound dressings represent a part of the management of diabetic foot ulceration. Normal saline (0.9%) wo...

Pectin is a heterogeneous hydrocolloid present in the primary cell wall and middle lamella in all dicotyledonous plants, more commonly in the outer fruit coat or peel as compared to the inner matrix. Presently, citrus fruits and apple fruits are the main sources for commercial extraction of pectin, but ongoing research on pectin extraction from alt...

Microgreens became evident specialty food product that attains quality and higher attention these days. Young foliaged greens are relished as a delicacy for its color, crunchiness and flavor. Microgreens are a novel category of wholesome vegetables which can be harvested after the emergence of primary leaves. Microgreens have fresh aroma and used a...

In current years, due to the growing global population and speedy environmental changes, various types of pathogens, microbes and extensive use of chemicals in agriculture has become the main reason for ensuring the safety of food. The presence of unsafe levels of pesticides, pathogens and microbes in food represents a serious threat to the safety...

: To observe the effects of propofol and etomidate induction on patients undergoing laproscopic cholecystectomies regarding serum cortisol level, hemodynamic parameters, pain on injection, myoclonus, and apnea on induction. : It is a prospective, randomized, double blind study. After approval from Institute Ethics Committee, sixty patients of age b...

Background In India, there are several malaria-endemic regions where non-falciparum species coexist with Plasmodium falciparum. Traditionally, microscopy and rapid diagnostic tests are used for the diagnosis of malaria. Nevertheless, microscopy often misses the secondary malaria parasite in mixed-infection cases due to various constraints. Misdiagn...

Sickle cell disease is a major public health problem in India. Lack of rapid and reliable diagnostic methods result in many avoidable deaths in affected population. Current diagnostic tools are laboratory based, expensive and need trained manpower. Here, we evaluated the performance of a microchip-based cellulose acetate electrophoresis test, “Gaze...

Purpose of the study Genetic variation is one of the major obstacles in the development of effective vaccines. A multivalent malaria vaccine is required to increase efficacy and confer long term protection. In this context, we analysed the genetic diversity, expression profile, and immune response against Pf34. Methods Phylogenetic analysis was ca...

The book contains 19 chapters on production technologies of horticulture crops as: 1. Horticulture 2. Orchard Designing & Planting Systems 3. Orchard Floor Management 4. Description of Fruit Crops 5. Description of Vegetable Crops 6. Nursery Raising Techniques in Fruit Crops 7. Nursery Raising Techniques in Vegetable Crops 8. Propagation Techniques...

The book contains 19 chapters on production technologies of horticulture crops as: 1. Horticulture 2. Orchard Designing & Planting Systems 3. Orchard Floor Management 4. Description of Fruit Crops 5. Description of Vegetable Crops 6. Nursery Raising Techniques in Fruit Crops 7. Nursery Raising Techniques in Vegetable Crops 8. Propagation Techniques...

The 2nd fully revised and expanded edition of the book Question Bank in Postharvest Technology has been fully uated with adequate number of MCQ's, Fill in The Blanks, Match the Followings and Glossary on the topic. With more than 1500 MCQs, 500 Fill in the Blanks and 300 match the Followings specifically on PST make the books a worth enough for eve...

The study was carried out for utilization of rainy season guava fruits cv. Shweta for preparation of foam mat dried guava fruit powder. The conversion of guava fruit pulp into foam was optimized by whipping the pulp after addition of glycerol monostearate (GMS) and drying the resultant foam in dehydrator (60±5 °C) to constant moisture content. Dryi...

Existing chronic co‐morbidities in a population affect the clinical outcome of infectious diseases. In order to devise better management strategies at community level, patients related clinicopathological as well as local health care infrastructure data is required. The use of digitised, unified, multilingual surveillance tool may facilitate real‐t...

Precise identification of Plasmodium species is critical in malaria control and elimination. Despite several shortcomings, microscopy and rapid diagnostic test (RDT) continue to be the leading diagnostic methods. Polymerase chain reaction (PCR) is the most sensitive method but its dependency on advanced laboratory and skilled workers limits its use...

The study was carried out for utilization of papaya and guava fruits pulp for preparation of foam mat dried fruit powder. The conversion of fruit pulp into foam was optimized by whipping the pulp after addition of carboxy-methyl-cellulose (CMC) and drying the resultant foam in dehydrator (60±5 °C) to constant moisture content. Drying of fruits pulp...

The revised edition of the book entitled “Objective Horticulture” has arisen from the fact that there is no objective type book covering all disciplines of horticulture (Fruit Science, Vegetable Science and Floriculture) as per revised syllabus prescribed by the ICAR. The book has been divided into 3 main sections viz; Section-I: Fruit Science Sect...

The study was carried out for utilization of papaya leaf for preparation of foam mat dried papaya leaf powder. The conversion of papaya leaf juice into foam was optimized by whipping the juice after addition of carboxy- methyl-cellulose (CMC) and drying the resultant foam in dehydrator (60±2°C) to constant moisture content. Drying of papaya leaf...

The study was carried out for utilization of rainy season guava fruits cv. Lalit for preparation of foam mat dried guava fruit powder. The conversion of guava fruit pulp into foam was optimized by whipping the pulp after addition of glycerol monostearate (GMS) and drying the resultant foam in dehydrator (60±5°C) to constant moisture content. Drying...

The brachial plexus block is an easy and relatively safe procedure for upper limb surgeries though there are different approaches to it, it is a block of roots, divisions and cords of the brachial plexus, out of which supraclavicular approach is most widely used method for anaesthesia and preoperative pain management in surgery below shoulder joint...

Cordia myxa L. is traditional medicinal tree with multiple uses such as vegetable, fodder and soil binder tree and used as delicacy in rural cuisine in summer and rainy season. The present study was an attempt about genetic variability, heritability and genetic advance among the important traits of lasuda crop and use this by modern techniques to d...

Method for juice extraction and storage of aonla juice cv. NA-7 and Desi (Seedling) aonla was optimized. Out of four different combinations, enzymatic pretreatment of grated aonla mass by adding 1000ppm pectinase enzyme at 50°C for 4 hours followed by juice extraction in screw type juice extractor resulted in a significant improvement in juice yiel...

Technology for utilization of guava fruit for preparation of dried slices was optimized by osmotic dehydration technique. The guava fruit cultivar Lalit and Shweta were selected for preparation of dried slices. The slices of 6 mm thickness were pre-treated with 0.2% KMS+0.5% CaCl2. The slices were then treated with different osmotic concentration v...

Protein isolates were obtained from defatted wild apricot press cake by isoelectric precipitation. The physico-chemical and functional properties of wild apricot protein isolate was significantly different. The wild apricot protein isolate had moisture content 12.67 per cent, ash content 5.84 per cent, crude protein 90.15 per cent, soluble per cent...

Accurate and timely diagnosis is very critical for management, control and elimination of the malaria. Malaria rapid diagnostic tests (RDTs) have improved the diagnosis and management of malaria in remote areas, community and places where microscopy is not available for diagnosis. According to WHO report 2018, Plasmodium falciparum malaria constitu...

Malaria remains a major health challenge in tropical and subtropical countries with an estimated incidence of 216 million cases and 445 000 deaths worldwide in 2016. Every 2 minutes a child under 5 years old dies because of malaria. India accounts for 80% of malaria cases and 60% of malaria deaths in the southeast Asia region (SEAR). Plasmodium fal...

Apple pomace, an industrial by-product generated from apple juice processing industries, is a good source of pectin. The method for pectin extraction has been standardized by autoclaving apple pomace flour for time intervals of 15, 30, 45 and 60 min at 121 °C. The extraction of pectin by using autoclave at 121°C for 60 min followed by precipitation...

The experiment entitled “Effect of Date of Sowing and Leaf Mulching on Mungbean under Custard Apple based Agri-Horti System” was carried out during kharif season of 2013-14. The experiment was carried out at the agroforestry block of Agronomy farm of Rajiv Gandhi South Campus, Brakachha Mirzapur (BHU). The field experiment was laid out in factorial...

Stenotic and occlusive diseases of the subclavian and brachiocephalic arteries can cause a significant morbidity as it can lead to symptomatic ischemia affecting the upper extremities, brain and, in some cases, the heart. An endovascular approach with primary stenting or provisional stenting has become the primary modality of revascularization of s...

Elevated natriuretic peptide levels in asymptomatic individuals without heart failure are associated with increased risk of adverse cardiovascular outcomes and may reflect subclinical cardiac dysfunction. In a sample of 313 asymptomatic individuals (51% women, mean age 61 years) with hypertension and diastolic dysfunction, we examined the associati...

AimsTo investigate the effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiency in early-stage hypertension.Methods and resultsWe studied 527 participants from two clinical trials assessing the effect of blood pressure lowering on diastolic function. Participants were aged ≥45 years with early-stage hypertensio...

Some principle characteristics like fruit, stone and kernel weight and kernel and oil recovery as crude oil and physico-chemical characteristics of apricot (Prunus armeniaca Linn.) kernel oils were determined in the stones collected from different locations of Himachal Pradesh. Mean fruit weight of apricot fruits ranged between 8.0-15.1 g with the...

Pharmacokinetic data suggests that the intravenous form of n-acetylcysteine (NAC) may be more effective than the oral formulation in preventing contrast induced nephropathy (CIN). NAC owing to its anti-oxidant properties might be beneficial for patients with acute coronary syndromes (ACS) who are at increased risk for CIN. The aim of this prospecti...

Background: Elevated Nt-pro-BNP levels are associated with increased risk for heart failure in asymptomatic individuals. The degree to which increased BNP is related to subclinical cardiac dysfunction in hypertension (HTN) is unclear.

HYPOTHESIS/ INTRODUCTION: We investigated whether diabetes modified the effectiveness of renin-angiotensin-aldosterone system (RAAS) inhibition on left ventricular hypertrophy (LVH) regression in hypertensive patients in the Aliskiren in Left Ventricular Hypertrophy (ALLAY) trial. Participants (n=465) with LVH and a BMI > 25 kg/m(2) were randomized...

Mitral regurgitation (MR) has been associated with adverse outcomes after myocardial infarction (MI). Without structural valve disease, functional MR has been related to left ventricular (LV) remodeling and geometric deformation of the mitral apparatus. The aims of this study were to elucidate the mechanistic components of MR after high-risk MI and...

The mechanisms responsible for the increased risk of heart failure (HF) post-myocardial infarction (MI) may differ between patients with versus without diabetes. We hypothesized that after high-risk MI, patients with diabetes would demonstrate patterns of remodeling that are suggestive of reduced ventricular compliance and that are associated with...

Our objective was to define the relationship between renal dysfunction--both albuminuria and reduced estimated glomerular filtration rate (eGFR)--and cardiac structure and diastolic dysfunction among patients with chronic hypertension. Both albuminuria and eGFR were measured in 540 asymptomatic patients with hypertension and diastolic dysfunction a...

Echocardiographic measurements of left ventricular (LV) function, predominantly LV ejection fraction (LVEF), have been used to define risk in patients after myocardial infarction. However, the extent to which measures of LV structure and function provide incremental prognostic value over clinical variables in survivors of high-risk myocardial infar...

The objective of this paper is to describe outcomes of endovascular therapy in patients with symptomatic common femoral artery (CFA) lesions. Symptomatic atherosclerotic disease of the common femoral artery is an uncommon clinical entity, and there is no consensus regarding the suitability of catheter-based therapy. We reviewed the records of 26 co...

IntroductionTherapeutic correction AnatomyClinical symptomsMedical therapy for vertebrobasilar diseaseVertebral artery revascularizationOutcomes dataConclusions References

The presence of heart failure or LV systolic dysfunction in the setting of acute myocardial infarction is associated with poor prognosis. Aldosterone is an important downstream mediator of the renin-angiotensin-aldosterone system which, in the post-acute myocardial infarction setting, promotes myocardial collagen deposition, myocardial fibrosis, ap...

We sought to investigate the clinical prognostic value of longitudinal and circumferential strain (S) and strain rate (SR) in patients after high-risk myocardial infarction (MI). Left ventricular (LV) contractile performance after MI is an important predictor of long-term outcome. Tissue deformation imaging might more closely reflect myocardial con...

Background: Renin-angiotensin system (RAS) breakthrough may occur in heart failure despite optimum ACE-inhibition (ACE-I). We examined the effect of adding the direct renin inhibitor aliskiren 150mg/d in patients in the ALOFT trial.

Mechanical dyssynchrony is considered an independent predictor for adverse cardiovascular outcomes in patients with heart failure. However, its importance as a risk factor after myocardial infarction is not well defined. We examined the influence of mechanical dyssynchrony on outcome in patients with left ventricular dysfunction, heart failure, or...

Both diastolic dysfunction and increased vascular stiffness represent important measures of target-organ damage in hypertension. Whether intensive blood pressure (BP) control can further improve these measures remains unknown. EXCEED is a prospective, randomized open-label blinded endpoint trial (PROBE) design, aiming to test the hypothesis that mo...

Diastolic dysfunction may precede development of heart failure in hypertensive patients. We randomized 228 patients with uncontrolled hypertension, preserved ejection fraction, and diastolic dysfunction to 2 targeted treatment strategies: intensive, with a systolic blood pressure target of <130 mm Hg, or standard, with a systolic blood pressure tar...

C-reactive protein (CRP) is a marker of systemic inflammation, and it has been implicated in the pathogenesis of many chronic diseases, including cardiovascular (CV) diseases. With highly sensitive CRP assays, serum CRP can add considerably to standard coronary heart disease risk factors and in the prediction of subsequent major CV risk. We review...

Inflammation plays a pivotal role in all phases of atherosclerosis. High-sensitivity C-reactive protein (hsCRP), the best characterized biomarker of inflammation, is an independent predictor of future cardiovascular (CV) events and can add further insight to risk stratification. Assessment of hsCRP levels in clinical practice is feasible and inexpe...

It is estimated that as many as 1,000,000 people in the United States have chronic symptomatic coronary artery disease (often referred to as refractory angina) that is recalcitrant to medical therapy and unamenable to conventional revascularization procedures. Patients have reproducible lifestyle-limiting symptoms of chest pain, shortness of breath...

Background : Impaired in renal function is associated with increased risk of cardiac events. The relationship between mild impairments in renal function and degree of diastolic dysfunction (DD) has not been well established. Methods : Estimated glomerular filtration rate (eGFR), urine albumin-to-creatine ratio (ACR) and echocardiographic measures w...

Background: Although both vascular and ventricular stiffness are increased in hypertension, the degree to which these abnormalities are related has not been well characterized Methods: Echocardiographic measures of LV structure and function were assessed in 384 patients enrolled in the VALsartan In Diastolic Dysfunction (VALIDD) trial with mild hyp...

Background: Hypertension is a risk factor for diastolic dysfunction (DD) and HF with preserved EF. We quantified the relationship between blood pressure (BP) reduction and improvement in DD across a broad range of BP. Methods: Baseline and follow-up BP and mitral annular early relaxation velocity (E′) were analyzed in 337 subjects with mild HTN (SB...

Left ventricular hypertrophy (LVH) is an independent risk factor and predictor of cardiovascular (CV) events and all-cause mortality. Patients with LVH are at increased risk for stroke, congestive heart failure, coronary heart disease, and sudden cardiac death. Left ventricular hypertrophy represents both a manifestation of the effects of hypertens...

LVDD as an early measure of myocardial end-organ damage is commonly associated with hypertension and may well precede development of LVH in hypertension. About half of the patients presenting with heart failure have a normal ejection fraction, a clinical syndrome that is commonly referred to as HFPEF or diastolic heart failure and is commonly assoc...

Hypertension clearly increases the risk of systolic or diastolic heart failure. With aging population and advancements in treatment of cardiovascular diseases, the prevalence of heart failure is ever-increasing and is a principal cause of cardiovascular morbidity and mortality. Treating hypertension has been shown to decrease the risk of developmen...

Left ventricular (LV) hypertrophy, a marker of cardiac end-organ damage, is associated with an increased risk of cardiovascular morbidity and mortality. Inhibitors of the renin-angiotensin-aldosterone system may reduce LV mass to a greater extent than other antihypertensive agents. We compared the effect of aliskiren, the first orally active direct...

To assess the relationship between left atrial (LA) size and outcome after high-risk myocardial infarction (MI) and to study dynamic changes in LA size during long-term follow-up. The VALIANT Echocardiography study prospectively enrolled 610 patients with left ventricular (LV) dysfunction, heart failure (HF), or both following MI. We assessed LA vo...

Objectives: This study sought to understand prognostic implications of increased baseline left ventricular (LV) mass and geometric patterns in a high risk acute myocardial infarction. Background: The LV hypertrophy and alterations in LV geometry are associated with an increased risk of adverse cardiovascular events. Methods: Quantitative echoc...

Loss of negative feedback inhibition of renin release during chronic treatment with an angiotensin-converting enzyme (ACE) inhibitor leads to a compensatory rise in renin secretion and downstream components of the renin-angiotensin-aldosterone (RAAS) cascade. This may overcome ACE inhibition but should be blocked by a direct renin inhibitor. We stu...

The presence of heart failure or left ventricular systolic dysfunction in the setting of acute myocardial infarction is associated with poor prognosis. Aldosterone is an important downstream mediator of the renin-angiotensin-aldosterone system that promotes myocardial collagen deposition, myocardial fibrosis, apoptosis, ventricular remodeling, and...

Background: Increasing urine albumin/creatinine ratio (ACR) is associated with systemic microvascular damage and increased cardiovascular morbidity and mortality. However, the relationship between albuminuria and left ventricular (LV) diastolic function, an early measure of myocardial end-organ damage in hypertension, has not been well defined. Met...

The purpose of this study was to determine whether alterations in cardiac structure or function contribute to the increased risk associated with renal impairment after myocardial infarction (MI). Renal impairment is associated with adverse cardiovascular outcomes after MI. Echocardiography was performed on 603 patients with left ventricular (LV) dy...

Diastolic dysfunction might represent an important pathophysiological intermediate between hypertension and heart failure. Our aim was to determine whether inhibitors of the renin-angiotensin-aldosterone system, which can reduce ventricular hypertrophy and myocardial fibrosis, can improve diastolic function to a greater extent than can other antihy...

Studies on dry storage of chrysanthemum (DelldrautlJema graudiflora Tzevlev) cv. Snow Ball flowers were carried out at Dr. Y.S. Parmar University of Horticulture and Forestry, Solan, during 1999-2001. Three wrapping materials viz., newspaper, cellophane wax paper and polythelene were used to store the flowers for 24, 48 and 72h at ambient storage,...

The role of the plasma membrane Ca2+ pump (PMCA) is to remove excess Ca2+from the cytosol to maintain low intracellular Ca2+ levels. Asp1080 lies within an acidic sequence between the C-terminal inhibitory region and the catalytic core of PMCAs and is part of the caspase-3 recognition site of isoform 4b. Caspase-3 cuts immediately after this residu...

The plasma membrane Ca2+ pump (PMCA) is an essential element in the complex of mechanisms that maintain low intracellular Ca2+ concentration in the living cell. This pump is tightly regulated by calmodulin through binding to a high affinity calmodulin-binding domain at the C terminus that also serves as an autoinhibitor of the enzyme. Inspection of...