Anh-Tuan Le

• Professor
• Managing Director at Phenikaa University

Surface-Enhanced Raman Scattering (SERS) is a powerful analytical tool, which is usually based on the use of noble metal nanoparticles. To further improve the performance of SERS sensors, the substrates have been modified, leading to the design and development of metal–semiconductor nanocomposites. In this work, a series of zinc oxide–silver (ZnO/A...

Demand for improving the properties of unsaturated polyester resins (UPRs), especially their UV resistance, has been steadily increasing. Enhancing these properties is essential for expanding the resin's applicability in outdoor environments. Recently, studies have focused on improving the properties of UPRs with functional inorganic nanomaterials...

Being well-known as an excellent sorbent, metal–organic frameworks (MOFs) have been employed to intergrate with noble metal nanoparticles to fabricate active substrates for surface-enhance Raman spectroscopy (SERS) sensing applications. In this work, we employed three organic molecules with different molecular dimensions, including urea, methylene...

Surface-enhanced Raman spectroscopy (SERS) is a renowned analytical technique for non-invasive molecular identification. Advancements in SERS technology pivot on designing nano-structured substrates to enhance sensitivity and reliability. A key emerging trend involves integrating pre-treatment and post-treatment techniques on these substrates, leve...

Surface-enhanced Raman spectroscopy (SERS) is widely recognized as a powerful analytical technique, offering molecular identification by amplifying characteristic vibrational signals, even at the single-molecule level. While SERS has been successfully applied for a wide range of targets including pesticides, dyes, bacteria, and pharmaceuticals, it...

Surface-enhanced Raman scattering (SERS) is a powerful, highly efficient analytical technique capable of providing label-free, non-invasive, rapid, and ultrasensitive molecular detection down to the single-molecule level. Despite its advantages, SERS remains largely confined to laboratory settings due to the complexities of substrate fabrication an...

In this study, Au–NiFe2O4 hetero-nanostructures (Au–NFO HNs) have been successfully developed and proposed as an efficient photoactive material for the construction of a photoelectrochemical sensor for the detection of paracetamol (PCM) under visible light irradiation. When Au NPs were in intimate contact with NFO NFs, a built-in electric field and...

This paper presents a novel Pre-and Post-Irradiation SERS (PI-PI SERS) technique that synergistically integrates photo-induced enhanced Raman scattering (PIERS) and photocatalysis within a single Ag/TiO2 nanocomposite structure to achieve ultrasensitive molecular detection and substrate reusability. The PI-PI SERS technique involves pre-irradiation...

A flexible, ultrasensitive, and practical SERS chip is presented based on a paper/f-TiO2/Ag structure. The chip enhances the self-assembly of Ag nanoparticles on a cellulose fiber matrix, facilitated by smart functionalized TiO2 nanomaterials (f-TiO2). This design enables superior detection of the hazardous pesticide tricyclazole (TCZ) on crops usi...

In this study, we describe experimental efforts to decipher the role of ZnCo2O4 nanoflakes (ZCO-NFs) for selective enhancement of voltammetric responses of screen-printed electrode (SPE) toward redox species system. The ZCO-NFs sample was characterized by X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscopy (SEM) and UV–vis spe...

Silver (Ag) and gold (Au) nanoparticles (NPs) are incorporated into the zeolitic imidazolate framework-8 (ZIF-8) host matrix, which is successfully coated the screen-printed electrodes (SPEs) for the effective detection of chloramphenicol (CAP). The morphological and structural characteristics are examined using scanning electron microscope (SEM) a...

This study introduces a novel method for the rapid and efficient detection of paracetamol, leveraging a colorimetric sensing mechanism predicated on the utilization of TMB-MnO2 nanosheets. The interaction of paracetamol with MnO2 is characterized by a selective reaction mechanism, leading to the reduction of MnO2 to Mn²⁺ ions and consequent attenua...

We have introduced potential modifiers synthesized from attached Ag nanoparticles (NPs) on MnO2 nanostructural surfaces, and fabricated an electrochemical sensor toward 4-nitrophenol (4-NP) detection. MnO2 with various morphologies (nanowires, nanorods, and nanosheets) has been prepared by hydrothermal and microwave-assisted hydrothermal methods, w...

Insight into the phase-dependent electron transfer kinetics and electrocatalytic activity of metal oxide nanostructures is important in the rational design of functional nanostructures for realizing high-performance electrochemical sensors. This study focuses on elucidating the effect of the crystalline phase on the electron transfer kinetics and e...

Paper/GO/e-Au SERS substrates were fabricated to detect tricyclazole on cucumber skin and in orange juice. A machine learning model was developed for data analysis and to distinguish tricyclazole from 9 other organic compounds.

An efficient photoactive spinel NiFe2O4 nanoflakes (NFO NFs) was successfully prepared and integrated into an electrochemical sensor for the sensitive determination of Azithromycin (AZM) under visible light illumination. With the introduction of 532 nm laser illumination, NFO NFs could be easily excited and induce the charge-separation state with e...

Silver nanoparticles (AgNPs) have been regarded as a highly promising substrate for surface-enhanced Raman scattering (SERS) sensors. In this study, we focused on the electrochemical synthesis method by developing three kinds of AgNPs using three different electrolytes: citrate (e-Ag-C), oleic acid (e-Ag-O) and fish mint (Houttuynia cordata Thunb.)...

Designing surface-enhanced Raman scattering (SERS) substrates that combine multiple advanced features in synergy is highly desirable for the SERS technique, however, it has been a long-standing challenge due to inherent trade-offs in feature selection. For instance, while nanoplasmonic surface functionalization bolsters attraction to target analyte...

The rapid and efficient detection of chloride (Cl⁻) ions is crucial in a variety of fields, making the development of advanced sensing methods such as colorimetric sensors an imperative advancement in analytical chemistry. Herein, a novel, selective, and straightforward paper-based colorimetric sensing platform has been developed utilizing an amorp...

A functional ternary substrate was developed for surface-enhanced Raman scattering (SERS) sensing systems. MnO2 nanosheets were synthesized by a simple and controllable hydrothermal method, followed by the integration of graphene oxide (GO) nanosheets. Subsequently, MnO2/GO nanostructures were decorated with plasmonic Ag nanoparticles (e-AgNPs). Th...

This report focuses on evaluating the influence of structural and physical properties of MoS2 material on electrochemical behaviors as well as sensing performance toward the detection of targeted chloramphenicol (CAP) molecules. The various MoS2 samples were fabricated via a simple ultrasonication route at different experimental times. Through usin...

In this work, a series of unsaturated polyester resin (UPRs)/electrochemically exfoliated graphene oxide (e-GO) polymer nanocomposites with different ratios of e-GO (0.05, 0.1, 0.15, and 0.2 wt%) were prepared via an in situ polymerization method. The surface morphology and structural and chemical properties of the original UPR and UPR/e-GO nanocom...

Metallic-Ag@ferromagnetic-Fe 3 O 4 nanoparticles have been used as a promising spintronics material to gain deeper insights into spintronics-related electrochemical reactions under the influence of an applied external magnetic field (MF) including spin polarization/transportation, and spin selectivity. Ferrocyanide/ferricyanide ([Fe(CN) 6 ] 3‒/4‒ )...

Titanium dioxide (TiO2) nanomaterials have been comprehensively studied in recent decades because of their possible practical applications in diverse fields, including photocatalysis, energy storage, sensing and biomedicine. Numerous strategies have been reported on preparing TiO2 nanostructures with regulated sizes, shapes and surface ligands; how...

Owing to the effective combination between MoS2 sheets with CuInS2 nanoparticles (NPs), a direct Z-scheme heterojunction was successfully constructed and proved as a promising structure to modify the working electrode surface with the aim of enhancing overall sensing performance towards CAP detection. Herein, MoS2 was employed as a high mobility ca...

The electrochemical behavior and sensing performance of an electrode modified with NiFe2O4 (NFO), MoS2, and MoS2-NFO were thoroughly investigated using CV, EIS, DPV, and CA measurements, respectively. MoS2-NFO/SPE provided a higher sensing performance towards the detection of clenbuterol (CLB) than other proposed electrodes. After optimization of p...

In this study, bio-Ag/ZnO NCs were synthesized via a microwave-assisted biogenic electrochemical method using mangosteen (Garcinia mangostana) peel extract as a biogenic reducing agent for the reduction of Zn2+ and Ag+ ions to form hybrid nanoparticles. The as-synthesized NC samples at three different microwave irradiation temperatures (Z 70, Z 80,...

This study introduces the bioformulations of Ag/BBR and ZnO/BBR complexes against pathogenic bacteria in the gastrointestinal tract. Without the use of toxic reduction agents, Ag and ZnO NPs were prepared using an electrochemical method and then facially mixed with BBR solution to form Ag/BBR and ZnO/BBR complexes. BBR molecules are strongly conjug...

The preparation of core/shell Ag@Fe 3 O 4 nanoparticles (NPs) and its potential application toward highly sensitive electrochemical detection of furazolidone (FZD) have been reported. UV–visible spectroscopy, X-ray diffraction, scanning electron microscopy, and Zeta sizer were systematically carried out to confirm the formation, size distribution,...

In-paper flexible SERS chips were simply prepared by immersing pieces of filter paper into colloidal silver nanoparticles (e-AgNPs) solution for 24 h and drying naturally at room temperature. Characteristic properties of cellulose fibers allowed the paper-based chips to be available for two sample collecting approaches. Being hydrophilic but insolu...

ZnFe2O4-based nanostructures, including ZnFe2O4 nanoparticles and ZnFe2O4/ZnO nanocomposite, were introduced on screen-printed electrodes surface (SPEs) for enhancing the selective electrochemical signals towards the chloramphenicol (CAP) and furazolidone (FZD) antibiotics. The difference in molecular structure of CAP and FZD leads to the significa...

Surface-enhanced Raman scattering (SERS) is a powerful analysis technique that allows both the identification and detection of analytes at trace levels. However, the low rate of charge transfer (CT) between noble-metal nanoparticles and several analytes prevents them from being effectively detected by SERS-based sensors. They are regarded as low Ra...

Using electrochemically exfoliated graphene oxide (GO)-modified screen-printed carbon electrodes for the detection of furazolidone (FZD), a nitrofuran antibiotic, was explored. In this study, we designed some GO samples possessing different oxygen functional group content/defect density by using ultrasonic irradiation or microwave techniques as sup...

In this report, cobalt ferrite nanoparticles (CoFe 2 O 4 NPs) synthesised from the co-precipitation method were strongly connected with graphene oxide nanosheets (GO) via ‘bridge molecules’- polyhexamethylene biguanide hydrochloride (PHMB)’. Silver (Ag) NPs were grown on the surface of CoFe 2 O 4 -GO nanocomposites to improve the electrical conduct...

Despite the utilization of external magnetic field (MF) in promoting the intrinsic unique features of magnetic nanomaterials in many different applications has been reported, however the origin of MF-dependent electrochemical behaviors as well as the electrochemical response of analytes at the electrode in sensor applications is still not clear. In...

This study describes the preparation of berberine (BBR) in nanoformulation to enhance its solubility and increase its antibacterial effectiveness against hospital-acquired infections. BBR nanoparticles (BBR NPs) were formed by antisolvent precipitation (ASP) using glycerol as a safe organic solvent. UV–vis absorption spectra demonstrated that the s...

In this study, Fe3O4 nanoparticles are prepared by the co‐precipitation method. γ‐Fe2O3 and α‐Fe2O3 nanoparticles are obtained by calcining Fe3O4 nanoparticles for 6 h at 200 and 600 °C. The physicochemical properties of the prepared nanoparticles are investigated by field‐emission scanning electron microscopy, X‐ray diffraction, Fourier transform...

MIL-53(Fe), MIL-101(Cr), and MIL-53(Al) were successfully prepared to modify an electrode surface. With the differences in porous textural parameters and metal nodes, the physical characteristics and electrochemical performance toward chloramphenicol (CAP) detection at each modified electrode were systematically evaluated via CV and DPV measurement...

Modern society has been facing serious health-related problems including food safety, diseases and illness. Hence, it is urgent to develop analysis methods for the detection and control of food contaminants, disease biomarkers and pathogens. As the traditional instrumental methods have several disadvantages, including being time consuming, and havi...

The present work reports efficient electrochemical nanosensors for the sensitive monitoring of 4-nitrophenol (4-NP) in tomato samples using various biosynthesized silver nanoparticles (bio-AgNPs). Three different bio-AgNP types were synthesized using natural plant extracts, including green tea (GT) leaf, grapefruit peel (GP), and mangosteen peel (MP),...

In this work, we investigated the effect of morphology on the analytical performance of α-Fe2O3 nanostructures-based electrochemical sensors toward chloramphenicol (CAP) antibiotic using three designed morphologies including α-Fe2O3 nano-tube (α-Fe2O3-T), α-Fe2O3 nano-rice (α-Fe2O3-R), and α-Fe2O3 nano-plate (α-Fe2O3-P). Among these morphologies, α...

In this study, the Pb2+ adsorption capacity of electrospun polyvinylidene fluoride/graphene oxide (PVDF/GO) membranes with different morphological characteristics and compositions were comprehensively compared. Firstly, the chemical characteristics, morphological characteristics and hydrophobicity relating to the adsorption capacity of electrospun...

Electrochemically synthesized gold nanoparticles (e-AuNPs) were deposited on aluminum substrates to fabricate effective surface enhanced Raman spectroscopy (SERS) sensors for thiram and CAP monitoring in food samples, between which the thiram sensor showed better performance in terms of sensibility, reliability and practicability. Regarding that th...

Gold nanoparticles (AuNPs) with a diameter range of 10–20 nm were synthesised by the electrochemical method. They were used to modify the working electrode surface of both screen-printed carbon electrodes (SPCEs) and screen-printed platinum electrodes (SPPtEs), aiming to identify a reliable electrode for the direct detection of chloramphenicol (CAP...

This paper presents a reliable solution to enhance the electron transfer and stability of screen-printed carbon electrodes (SPCEs) for the direct detection of pathogenic bacteria. A nanocomposite of silver nanoparticles (AgNPs) and reduced graphene oxide (rGO) was used to modify the SPCEs. Herein, the nanocomposite was synthesized via a hydrotherma...

In this study, a strategy for improving the electrochemical response of chloramphenicol (CAP) was developed through the modification of a screen-printed electrode (SPE) with reduced graphene oxide-wrapped silver nanoparticles (Ag@GO). Incorporating silver nanoparticles and reduced graphene oxide into the nanohybrid structure can facilitate electron...

Acrylamide (AA) which occurs during carbohydrate-rich foods processed at high temperatures has been known as a neurotoxic, genotoxic, and probable carcinogenic compound to humans. In this study, thiourea (TU) is used as a supporting agent for the direct recognition of AA based on the cross-linking aggregation of electrochemically synthesized colloi...

In this work, Ag@ZnO and Ag@ZnO/MgAC photocatalysts were synthesized using a simple two-step electrochemical method by the addition of magnesium aminoclay (MgAC) as a great stabilizer and a Lewis base, which could donate electrons for reduction of Ag+ and Zn2+ ions, facilitating uniform formation as well as effective inhibition of aggregation of Ag...

In this study, we have developed, for the first time, a colorimetric and surface-enhanced Raman scattering (SERS) dual-mode sensing platform for sensitive amoxicillin (AMX) detection by employing electrochemically-synthesized copper nanoparticles (CuNPs) and copper-graphene oxide (Cu-GO) nanocomposites with low cost and high purity. The obtained re...

Thiram plays a critical role in protecting fruits and vegetables from damage by various crop diseases, but its residues significantly affect the environment, such as soil and water pollution, and becoming a serious threat to human health. Herein, Tween 80-capped copper nanoparticles (Tween 80-CuNPs) were developed as a convenient and low-cost color...

Multifunctional nanocomposites have received great attention for years; electron transfer (ET) is considered as an explanatory mechanism for enhancement of performance of these nanostructures. The existence of this ET process has been proved in many studies using either experimental or computational approaches. In this study, a ternary nanocomposit...

An electrochemical approach has been used for green synthesis of gold and silver nanoparticles (e-AuNPs and e-AgNPs) with high levels of purity and scalability. The electrochemically synthesized noble-metal nanoparticles were characterized by ultraviolet–visible (UV–Vis) spectroscopy and scanning electron microscopy (SEM), confirming the formation...

The rational design of nanomaterials for electrochemical nanosensors from the perspective of structure-property-performance relationships is a key factor in improving the analytical performance toward residual antibiotics in food. We have investigated the effects of the crystalline phase and copper loading amount on the detection performance of Cu-...

Zinc Ferrite (ZnFe2O4, ZFO) nanoparticles (NPs) as a multi-sensing material are successfully synthesised via a hydrothermal method and a following annealing treatment. The as-prepared ZFO-NPs were applied in electrochemical and mass-type sensors by depositing NPs directly on the screen-printed electrode (SPE) and the active electrode of a quartz cr...

Trong bài báo này, chúng tôi báo cáo kết quả tổng hợp vật liệu tổ hợp nano CoFe2O4/GO bằng phương pháp đồng kết tủa kết hợp vi sóng. Hạt nano CoFe2O4 sau khi tổng hợp đã xuất hiện trên bề mặt của GO. Hình thái bề mặt và cấu trúc của tổ hợp nano CoFe2O4/GO được khảo sát bằng nhiễu xạ tia X (XRD), hiển vi điện tử quét phát xạ trường (FESEM), phổ hồng...

The sensing material plays a very important role in determining the sensing properties of a gas sensor. In order to synthesise the sensing material, the precursors have a large effect on the properties of the sensing material. In this study, three types of γ-Fe2O3 nanoparticles were prepared with different ferric ion concentrations of [Fe³⁺] and [F...

In this work, an eco-friendly approach for the synthesis of biogenic silver nanoparticles (bio-AgNPs) using botanical extracts in combination with an electrochemical process was carried out. We employed three types of plant extracts, including green tea leaf (GTE), grapefruit peel (GP), and mangosteen peel (MP) extracts to successfully synthesize t...

Featured Application A magnetic respiratory sensor can be potentially employed to identify respiratory-related diseases like COVID-19 and track its progress in real time. Abstract Breathing is vital to life. Therefore, the real-time monitoring of a patient′s breathing pattern is crucial to respiratory rehabilitation therapies, such as magnetic res...

For mitigating environmental pollution caused by excess usage of urea fertilizer, this paper reports a new fertilizer formulation, based on urea incorporating chitosan (CS) and poly (vinyl alcohol) (PVA) blend, for the slow release of urea. The urea/CS/PVA formulations were prepared by cross-linking CS and PVA blend in the presence of urea with glu...

For the first time, the influences of phase purity and crystallinity on the electrochemical and electrocatalytic properties of CuCo 2 O 4 (CCO) and CuFe 2 O 4 (CFO)-based electrochemical sensors for the detection of chloramphenicol (CAP) are reported. A series of CCO and CFO nanoparticles were prepared by a modified coprecipitation method and then...

Breathing is vital to life. Therefore, the real-time monitoring of breathing pattern of a patient is crucial to respiratory rehabilitation therapies such as magnetic resonance exams for respiratory-triggered imaging, chronic pulmonary disease treatment, and synchronized functional electrical stimulation. While numerous respiratory devices have been...

An efficient colorimetric probe based on surface-functionalized silver nanoparticles (AgNPs) was prepared for sensitive thiram pesticide detection in water samples. The influence of various surface capping agents including polyhexamethylene biguanide hydrochloride (PHMB), polyvinylpyrrolidone (PVP) and anion BH4- on the performance of colorimetric...

This study reports a scalable green electrochemical synthesis of novel biogenic silver nanoparticles colloid (biogenic AgNPs) in large scale up to 5 liters using the bulk silver bar and the green tea leaves (Camellia sinensis) extract (GTE) as reducing agent during the electrochemical process. Under a direct-current voltage source, the biomolecules...

Fe3O4/FeOOH nanocomposites were synthesized by a simplistic precipitation method for high-performance gas sensing applications. A spray-coating method was used to deposit a sensitive film of Fe3O4/FeOOH nanocomposites on a quartz crystal microbalance (QCM). The structural and morphological characteristics were analyzed by using X-ray diffraction (X...

This study presents a cholesterol biosensor that uses cerium oxide nanorods (CeO2-NRs) as a platform for cholesterol oxidase (ChOx) attachment. The properties of the synthesized CeO2-NRs were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), and transmission electron microscopy (TEM). The ChOx/CeO2-NR-m...