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Angelique Cramer

Angelique Cramer
Amsterdam UMC

About

85
Publications
87,686
Reads
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17,092
Citations
Additional affiliations
May 2013 - present
University of Amsterdam
Position
  • Professor (Assistant)
Description
  • My main research interests: - network models for psychological phenomena - complex dynamical systems - measurement invariance - theories of measurement - solutions to the multiple comparison problem
April 2008 - April 2013
University of Amsterdam
Position
  • PhD Student

Publications

Publications (85)
Article
Full-text available
Experiencing stressful or traumatic events can lead to a range of responses, from mild disruptions to severe and persistent mental health issues. Understanding the various trajectories of response to adversity is crucial for developing effective interventions and support systems. Researchers have identified four commonly observed response trajector...
Preprint
Full-text available
Resilience refers to the ability to return to normal psychological functioning despite facing adversity. It remains an open question how to anticipate and study resilience, due to its dynamic and multifactorial nature. This paper presents a novel formalized simulation framework for studying resilience from a complex systems perspective. From this v...
Article
Full-text available
Ecological Momentary Assessment (EMA) in which participants report on their moment-to-moment experiences in their natural environment, is a hot topic. An emerging field in clinical psychology based on either EMA, or what we term Ecological Retrospective Assessment (ERA) as it requires retrospectivity, is the field of personalized feedback. In this...
Article
Full-text available
In recent years, network approaches to psychopathology have sparked much debate and have had a significant impact on how mental disorders are perceived in the field of clinical psychology. However, there are many important challenges in moving from theory to empirical research and clinical practice and vice versa. Therefore, in this article, we bri...
Preprint
Ecological Momentary Assessment (EMA), in which participants report on their moment-to-moment experiences in their natural environment, is a hot topic. An emerging field in clinical psychology based on either EMA, or what we term Ecological Retrospective Assessment (ERA) as it requires retrospectivity, is the field of personalized feedback. In this...
Article
Full-text available
Researchers have extensively studied fatigue, depression and anxiety in cancer patients. Several risk and protective factors have been identified for these symptoms. As most studies address these constructs, independently from other symptoms and potential risk and protective factors, more insight into the complex relationships among these construct...
Article
Full-text available
There is currently a lack of understanding of the structure of personality disorder (PD) trait facets. The network approach may be useful in providing additional insights, uncovering the unique association of each PD trait facet with every other facet. A unique feature of network analysis is centrality, which indicates the importance of the role a...
Article
Full-text available
In recent years, there has been a growing recognition of a dissociative subtype of posttraumatic stress disorder (D‐PTSD), characterized by experiences of depersonalization (DP) and derealization (DR), among individuals with PTSD. Little is known, however, about how experiences of DP and/or DR are associated with the experience of other PTSD sympto...
Article
Background: From around 1980, antidepressants (ad) have increasingly been prescribed, for longer periods of time, especially selective serotonin reuptake inhibitors (ssris). Paradoxically, their effectiveness is still doubted, especially outside the psychiatric profession. AIM: To explain increase and offer a perspective on causes and solutions, a...
Article
Full-text available
Background Antidepressant medications (ADMs) are widely used and long-term use is increasing. Given this extensive use and recommendation of ADMs in guidelines, one would expect ADMs to be universally considered effective. Surprisingly, that is not the case; fierce debate on their benefits and harms continues. This editorial seeks to understand why...
Article
Full-text available
As proposed in a prominent developmental model, social anxiety has different manifestations: social fear, shy temperament, anxious cognitions, and avoidance of social situations. Drawing from this model, we used the network approach to psychopathology to gain a detailed understanding of specific social anxiety components and their associations. The...
Article
Full-text available
Resilience is still often viewed as a unitary personality construct that, as a kind of antinosological entity, protects individuals against stress-related mental problems. However, increasing evidence indicates that maintaining mental health in the face of adversity results from complex and dynamic processes of adaptation to stressors that involve...
Article
Full-text available
(Accepted version before proof). Resilience is still often viewed as a unitary personality construct that, as a kind of anti-nosological entity, protects individuals against stress-related mental problems. However, increasing evidence indicates that the maintenance of mental health in the face of adversity results from complex and dynamic processes...
Article
We address the commentaries on our target article in terms of four major themes. First, we note that virtually all commentators agree that mental disorders are not brain disorders in the common interpretation of these terms, and establish the consensus that explanatory reductionism is not a viable thesis. Second, we address criticisms to the effect...
Article
Background Research in depression has progressed rapidly over the past four decades. Yet depression rates are not subsiding and treatment success is not improving. We examine the extent to which the gap between science and practice is associated with the level of integration in how depression is considered in research and stakeholder-relevant docum...
Article
Full-text available
Steinley, Hoffman, Brusco, and Sher (2017) proposed a new method for evaluating the performance of psychological network models: fixed-margin sampling. The authors investigated LASSO regularized Ising models (eLasso) by generating random datasets with the same margins as the original binary dataset, and concluded that many estimated eLasso paramete...
Article
Full-text available
Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology and psychiatry. Fundamental to the network theory of psychopathology is the role of specific symptoms and their interactions. Current statistical tools, however, fail to fully capture this constitutional property. We pr...
Article
It is not clear if treatments for depression targeting repetitive negative thinking (RNT: rumination, worry and content-independent perseverative thinking) have a specific effect on RNT resulting in better outcomes than treatments that do not specifically target rumination. We conducted a systematic search of PsycINFO, PubMed, Embase and the Cochra...
Preprint
Full-text available
Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology and psychiatry. Fundamental to the network theory of psychopathology is the role of specific symptoms and their interactions. Current statistical tools, however, fail to fully capture this constitutional property. We pr...
Preprint
Full-text available
Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology and psychiatry. Fundamental to the network theory of psychopathology is the role of specific symptoms and their interactions. Current statistical tools, however, fail to fully capture this constitutional property. We pr...
Chapter
Full-text available
The network approach to clinical psychology is a relatively new approach and diverges on various aspects from existing models and theories. The hallmark of the theory is that there is no common cause that underlies a set of symptoms. Instead, the network approach starts out by assuming that symptoms causally interact with each other. In this chapte...
Article
Full-text available
In the past decades, reductionism has dominated both research directions and funding policies in clinical psychology and psychiatry. However, the intense search for the biological basis of mental disorders has not resulted in conclusive reductionist explanations of psychopathology. Recently, network models have been proposed as an alternative frame...
Article
Full-text available
Recent literature has introduced (a) the network perspective to psychology and (b) collection of time series data to capture symptom fluctuations and other time varying factors in daily life. Combining these trends allows for the estimation of intraindividual network structures. We argue that these networks can be directly applied in clinical resea...
Preprint
Steinley, Hoffman, Brusco and Sher (2017) proposed a new method for evaluating the performance of psychological network models: fixed-margin sampling. The authors investigated LASSO regularized Ising models (eLasso) by generating random datasets with the same margins as the original binary dataset, and concluded that many estimated eLasso parameter...
Article
Full-text available
Forbes, Wright, Markon, and Krueger (2017) stated that “psychopathology networks have limited replicability” (p. 1011) and that “popular network analysis methods produce unreliable results” (p. 1011). These conclusions are based on an assessment of the replicability of four different network models for symptoms of major depression and generalized a...
Preprint
Recent literature has introduced (1) the network perspective to psychology, and (2) collection of time-series data in order to capture symptom fluctuations and other time varying factors in daily life. Combining these trends allows for the estimation of intra-individual network structures. We argue that these networks can be directly applied in cli...
Article
Full-text available
Since the introduction of mental disorders as networks of causally interacting symptoms, this novel framework has received considerable attention. The past years have resulted in over 40 scientific publications and numerous conference symposia and workshops. Now is an excellent moment to take stock of the network approach: What are its most fundame...
Preprint
Full-text available
Forbes, Wright, Markon, and Krueger (2017) state that “psychopathology networks have limited replicability” and that “popular network analysis methods produce unreliable results”. These conclusions are based on an assessment of the replicability of four different network models for symptoms of major depression and generalized anxiety across two sam...
Article
Full-text available
Purpose: The network perspective on psychopathology understands mental disorders as complex networks of interacting symptoms. Despite its recent debut, with conceptual foundations in 2008 and empirical foundations in 2010, the framework has received considerable attention and recognition in the last years. Methods: This paper provides a review of...
Article
Full-text available
Recent literature has introduced (1) the network perspective to psychology, and (2) collection of time-series data in order to capture symptom fluctuations and other time varying factors in daily life. Combining these trends allows for the estimation of intra-individual network structures. We argue that these networks can be directly applied in cli...
Article
Full-text available
In this paper, we characterize major depression (MD) as a complex dynamic system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be characterized by their own network with unique architecture and resulting dynamics. With respect to architecture, we show...
Preprint
Since the introduction of mental disorders as networks of causally interacting symptoms, this novel framework has received considerable attention. The past years have resulted in over 40 scientific publications and numerous conference symposia and workshops. Now is an excellent moment to take stock of the network approach: what are its most fundame...
Article
Full-text available
In this paper, we characterize major depression (MD) as a complex dynamic system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be characterized by their own network with unique architecture and resulting dynamics. With respect to architecture, we show...
Preprint
In this paper, we characterize major depression (MD) as a complex dynamical system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be characterized by their own network with unique architecture and resulting dynamics. With respect to architecture, we sh...
Article
Full-text available
The question of whether psychopathology constructs are discrete kinds or continuous dimensions represents an important issue in clinical psychology and psychiatry. The present paper reviews psychometric modelling approaches that can be used to investigate this question through the application of statistical models. The relation between constructs a...
Article
Objective: We propose a novel paradigm to predict acute attacks and exacerbations in chronic episodic disorders such as asthma, cardiac arrhythmias, migraine, epilepsy, and depression. A better generic understanding of acute transitions in chronic dynamic diseases is increasingly important in critical care medicine because of the higher prevalence...
Article
Full-text available
In this paper, we characterize major depression (MD) as a complex dynamic system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be characterized by their own network with unique architecture and resulting dynamics. With respect to architecture, we show...
Article
In this paper, we characterize major depression (MD) as a complex dynamic system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be characterized by their own network with unique architecture and resulting dynamics. With respect to architecture, we show...
Article
Full-text available
Mental disorders have traditionally been conceptualized as latent variables, which impact observable symptomatology. Recent alternative approaches, however, view mental disorders as systems of mutually reinforcing symptoms, and utilize network models to analyze the structure of these symptom-symptom interactions. This paper gives an introduction to...
Article
Full-text available
Conflict-affected populations are exposed to stressful events during and after war, and it is well established that both take a substantial toll on individuals’ mental health. Exactly how exposure to events during and after war affect mental health is a topic of considerable debate. Various hypotheses have been put forward on the relation between s...
Research
Full-text available
A recent study by Cai et al. (2015) on the genetics of major depression published in Nature (DOI: 10.1038/nature14659) was hailed in the media as a major insight into the underlying biology of depression. In this commentary, Sophie van der Sluis, Angelique Cramer and I briefly summarize the study and explain why we disagree with the interpretation...
Article
Full-text available
http://authors.elsevier.com/a/1QhogL4LCa4Wz Network analysis represents a novel theoretical approach to personality. Network approaches motivate alternative ways of analyzing data, and suggest new ways of modeling and simulating personality processes. In the present paper, we provide an overview of network analysis strategies as they apply to perso...
Chapter
What is the nature of mental disorders such as major depression and panic disorder? Are mental disorders analogous to tumors, in that they exist as separate entities somewhere in people's minds? Do mental disorders cause symptoms such as insomnia and fatigue? Until very recently, it was exactly this sort of thinking that (implicitly) permeated many...
Article
Full-text available
Spousal bereavement can cause a rise in depressive symptoms. This study empirically evaluates 2 competing explanations concerning how this causal effect is brought about: (a) a traditional latent variable explanation, in which loss triggers depression which then leads to symptoms; and (b) a novel network explanation, in which bereavement directly a...
Article
Full-text available
Many empirical researchers do not realize that the common multiway analysis of variance (ANOVA) harbors a multiple comparison problem. In the case of two factors, three separate null hypotheses are subject to test (i.e., two main effects and one interaction). Consequently, the probability of at least one Type I error (if all null hypotheses are tru...
Code
Interactive, agent-based simulation tool that demonstrates vulnerability to depression according to the network perspective. If you want to run it, you can download NetLogo 6.0 here: http://ccl.northwestern.edu/netlogo/6.0/ This interactive model contains an ”Info” tab, which contains an explanation of the model as well as some guidelines on how to...
Article
Full-text available
Significance As complex systems such as the climate or ecosystems approach a tipping point, their dynamics tend to become dominated by a phenomenon known as critical slowing down. Using time series of autorecorded mood, we show that indicators of slowing down are also predictive of future transitions in depression. Specifically, in persons who are...
Article
Full-text available
In psychological measurement, two interpretations of measurement systems have been developed: the reflective interpretation, in which the measured attribute is conceptualized as the common cause of the observables, and the formative interpretation, in which the measured attribute is seen as the common effect of the observables. We advocate a third...
Article
Full-text available
In network approaches to psychopathology, disorders result from the causal interplay between symptoms (e.g., worry → insomnia → fatigue), possibly involving feedback loops (e.g., a person may engage in substance abuse to forget the problems that arose due to substance abuse). The present review examines methodologies suited to identify such symptom...
Article
We welcome the recommendations suggested by Asendorpf et al. Their proposed changes will undoubtedly improve psychology as an academic discipline. However, our current knowledge is based on past research. We therefore have an obligation to 'dwell on the past'; that is, to investigate the veracity of previously published findings-particularly those...
Article
Full-text available
In one currently dominant view on personality, personality dimensions (e.g. extraversion) are causes of human behaviour, and personality inventory items (e.g. 'I like to go to parties' and 'I like people') are measurements of these dimensions. In this view, responses to extraversion items correlate because they measure the same latent dimension. In...
Article
Full-text available
Some commentators wholeheartedly disagreed with the central tenet of the network perspective on personality, namely that traits are the result of mutual interactions between thoughts, feelings and behaviours. In this rejoinder, we primarily focus on these commentaries by (i) clarifying the main differences between the latent versus the network view...
Article
Full-text available
Lindquist et al. present a strong case for a constructionist account of emotion. First, we elaborate on the ramifications that a constructionist account of emotions might have for psychiatric disorders with emotional disturbances as core elements. Second, we reflect on similarities between Lindquist et al.’s model and recent attempts at formulating...
Article
Full-text available
We present the qgraph package for R, which provides an interface to visualize data through network modeling techniques. For instance, a correlation matrix can be rep-resented as a network in which each variable is a node and each correlation an edge; by varying the width of the edges according to the magnitude of the correlation, the structure of t...
Article
Full-text available
Newton (this issue) proposes various fruitful directions in which to divert the current consensus definition of validity and its implications as entertained in the 1999 Standards for educational and psychological testing. In both Newton’s proposed clarification as well as in the Standards definition, validity is closely associated with measurements...
Article
Full-text available
Previous research has shown that stressful life events (SLEs) influence the pattern of individual depressive symptoms. However, we do not know how these differences arise. Two theories about the nature of psychiatric disorders have different predictions about the source of these differences: (1) SLEs influence depressive symptoms and correlations b...
Article
Full-text available
Mental disorders are highly comorbid: people having one disorder are likely to have another as well. We explain empirical comorbidity patterns based on a network model of psychiatric symptoms, derived from an analysis of symptom overlap in the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV). We show that a) half of the symptoms in...
Article
Full-text available
Nolen-Hoeksema and Watkins (2011, this issue) propose a useful model for thinking about transdiagnostic processes involved in mental disorders. Here, we argue that their model is naturally compatible with a network account of mental disorders, in which disorders are viewed as sets of mutually reinforcing symptoms. We show that network models are ty...
Article
The missing heritability problem is pervasive and Johnson, Penke and Spinath (2011) present a number of compelling reasons for its existence. In this comment, we present another reason for the apparent discrepancy between heritability estimates and gene‐hunting results in psychopathological research: if syndromes are networks of causally related sy...