Angelina Borizanova

• Medical Doctor at Medical University of Sofia

Background Atrial fibrillation (AF) is the most common cardiac arrhythmia, where the focus of echocardiographic evaluation is the left atrium (LA), as a substrate for the arrhythmia(1). But AF is not only a disease of the LA, it also affects the right atrium (RA) (2). Available data on structural changes of RA in AF are scarce, and even more in rel...

Background: The prevalence of obesity and hypertension among healthcare professionals has been previously described. Both diseases are known risk factors for atrial cardiomyopathy (ACM), a new clinical entity with potential to be a determinant of heart failure, atrial fi brillation and thromboembolic complications. In this perspective, early prevent...

Background: Arterial hypertension is the most common factor for structural and functional changes in the heart, but these changes are observed in more advanced stages and in patients with poor control of arterial hypertension. Echocardiography plays a key role in detecting these changes, but a more detailed assessment is needed to identify early ch...

Systemic lupus erythematosus is a chronic autoimmune disorder affecting predominantly young women. Cardiac involvement in systemic lupus erythematosus is common and the typical manifestations are pericarditis, myocarditis, valvular disease, coronary artery disease, cardiac arrhythmias, and congestive heart failure. Clinical lupus myocarditis typica...

Background Atrial cardiomyopathy (ACM) is a new clinical entity with significant importance, because of its potential to be a determinant of heart failure, atrial fibrillation and thromboembolic complications¹. Defining different atrial phenotypes is challenging, because of the lack of consensus for the diagnosis of ACM²'³. Menopausal transition is...

Background: Acute decompensated heart failure (ADHF) is a condition with a high frequency of hospitalizations and mortality, and obstructive sleep apnea (OSA) is a common comorbidity. Continuous positive airway pressure (CPAP) therapy at home can be a good adjunctive non-drug therapy for these patients. Methods: We conducted a single-center, prospe...

Background: Trimethylamine N-oxide (TMAO) is synthesized by the intestinal microbiota and is an independent predictor of cardiovascular disease (CVD). However, its underlying mechanisms remain unclear. We investigated TMAO levels across different CVD-risk patient groups, and evaluated associations between TMAO and vascular alterations (e.g., arteri...

Funding Acknowledgements Type of funding sources: None. Background Obesity and atrial fibrillation (AF) are emerging health problem, associated with significant morbidity and mortality. There is a significant relation between body mass index (BMI) on one hand and the amount of visceral fat and epicardial adipose tissue (EAT) on the other (1,2). EA...

Funding Acknowledgements Type of funding sources: None. Background Atrial fibrillation (AF) is a progressive disease and can initiates and maintains in the absence of left atrial (LA) enlargement¹´². Echocardiographic parameters of LA mechanics had been proposed for best dealing with patients in AF³ . Combining different laboratory biomarkers with...

Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): Medical University - Sofia Background Often accompanying comorbidity in patients with acute heart failure and overweight is sleep disorders. Searching and treatment of sleep apnea will be helpful in these patients. CPAP therapy may improve the prognosis....

Unlabelled: Chest pain and dyspnoea are among the most common complaints seen in the emergency room and each symptom calls for a broad differential diagnosis. Large hiatal hernias are infrequent, but they can lead to atypical symptoms mimicking different cardiovascular, pulmonary and neoplastic diseases. We present two cases of older patients with...

Objective: Increased arterial stiffness is an early predictor of cardiovascular changes. However the association between arterial stiffness with LV myocardial changes is poorly understoodThe aim of this study was to examine the relationship between arterial stiffness and LV function in well - controlled hypertensive patients.Methods: A total 100 c...

Aim: The aim of the study was to establish echocardiographic predictors of AF in middle-aged patients without overt heart disease. Methods: Prospective consecutive patients with AF (n= 936), who had been admitted for sinus rhythm restoration in our hospital for the period January 2016-December 2018, were screened for participation in the study. A t...

Objective Arterial stiffness is an independent risk factor in arterial hypertension, but little is known about the association between left atrial remodeling and arterial stiffness in middle – aged hypertensive patients. AIM To investigate the early changes in left atrial (LA) mechanical function and parameters of arterial stiffness in a populatio...

Funding Acknowledgements Type of funding sources: None. BACKGROUND Arterial hypertension (HTN) is the most prevalent risk factor for Atrial fibrillation (AF) through structural and functional changes of the left atrium. Paroxysmal AF is mainly asymptomatic and silent forms in patients with HTN are associated with thromboembolic complications. Howe...

Background Non-invasive measurements of 24 h ambulatory central aortic systolic pressure (24hCASP) is now feasible method than single measurement of CASP. There is growing interest in CASP as cardiovascular risk marker beyond conventional brachial blood pressure (BP). Pulse wave velocity estimates arterial stiffness, whereas CASP is representative...

Background Left atrial volume index (LAVi) has been established as a surrogate marker for chronically elevated left ventricular (LV) filling pressure. Moreover it is a powerful predictor of atrial fibrillation (AF) in different pathologies. However, there is limited data for additional and sensitive echocardiographic predictors of AF in patients wi...

Topic(s): Risk Factors and Prevention-Cardiovascular Risk Assessment Citation: Background: The 24hour central aortic pressure is an early predictor of cardiovascular complications in hypertension. However, the association between arterial stiffness and left ventricular dysfunction is poorly understood.

Background Left ventricular (LV) global longitudinal strain (GLS) is a more sensitive parameter than ejection fraction in the assessment of LV function. It has been established as a predictor of cardiac death and adverse events. In patients with dilated cardiomyopathy (DCM) LV deformation and twist mechanics are reduced in varying degrees. Purpose...

BACKGROUND Vascular stiffness and left atrial volume index (LAVI) are predictors of cardiovascular complications in hypertensive patients. The correlation of left atrium (LA) with left ventricle (LV) – arterial functional changes has not been well established. PURPOSE To investigate the relationship between LA remodeling and ventriculoarterial fun...

Topic(s): Risk Factors and Prevention-Cardiovascular Risk Assessment Citation: BACKGROUND: The concept of "ventriculoarterial coupling" could be a key determinant for the prediction of cardiovascular events. The interaction between left atrium (LA) and ventriculoarterial coupling for evaluation of functional abnormalities remains unclear.

https://pdfs.journals.lww.com/jhypertension/2019/07001/ASSOCIATION_BETWEEN_CENTRAL_AORTIC_PRESSURE_AND.884.pdf?token=method|ExpireAbsolute;source|Journals;ttl|1599214647093;payload|mY8D3u1TCCsNvP5E421JYK6N6XICDamxByyYpaNzk7FKjTaa1Yz22MivkHZqjGP4kdS2v0J76WGAnHACH69s21Csk0OpQi3YbjEMdSoz2UhVybFqQxA7lKwSUlA502zQZr96TQRwhVlocEp/sJ586aVbcBFlltKNKo+tbuMfL...

Galectin 3, reccurent Atrial fibrillation

Introduction: Transthyretin familial amyloid polyneuropathy (TTR-FAP) is a rare, progressive, life-threatening, hereditary disorder caused by mutations in the transthyretin gene. TTR-FAP is frequently diagnosed late because the disease is difficult to recognize due to phenotypic heterogeneity. In TTR-FAP gastrointestinal (GI) disturbances play an i...

Aim: The aim was to investigate twist alterations depending on the degree of functional mitral regurgitation (MR) by speckle-tracking echocardiography. Methods: Sixty-three patients with symptomatic dilated cardiomyopathy (DCM) were included. Patients were divided according to MR vena contracta width (VCW): group 1 with VCW <7 mm (mild/moderate...

Along with the development of evidence based medicine, the so-called „Medicine in cooperation with the patient” has emerged recently due to the need to satisfy not only the medical needs of the patients but also their psychological needs. A convenient approach to monitoring these requirements of patients is the QoL. The purpose of the present study...

Cardiovascular diseases (CVDs) are a major factor in disabling the human population and they are associated with signiÞ cant decrease in the quality of life (QoL) in these patients. The aim of the study was to assess the QoL of patients with CVDs and to analyze the aspects that can be improved. The subjects of this cross-sectional study were 215...

In the analysis of the quality of life (QoL) in patients with cardiovascular disease (CVD), different approaches can be applied. The subjective approach involves perceiving, understanding and assessing the impact of the disease on a patient basis due to the fact that objective factors are subjectively interpreted by the patient with chronic dise...