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14
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Introduction
Additional affiliations
December 1993 - present
Publications
Publications (14)
To evaluate the impact of enhanced slow wave sleep (SWS) on behavioral, psychological, and physiological changes resulting from sleep restriction.
A double-blind, parallel group, placebo-controlled design was used to compare gaboxadol (GBX) 15 mg, a SWS-enhancing drug, to placebo during 4 nights of sleep restriction (5 h/night). Behavioral, psychol...
To evaluate the impact of enhanced slow-wave sleep (SWS) on behavioral, psychological, and physiologic changes resulting from sleep restriction
A double-blind, parallel-group, placebo-controlled design was used to compare tiagabine, 8 mg, (a SWS-enhancing drug) to placebo during 4 nights of sleep restriction (time in bed = 5 hours per night). Behav...
To evaluate the effects of napping, caffeine, and napping plus caffeine on performance and alertness in both laboratory and field settings.
(1) Laboratory Study: parallel-groups design with random assignment to 1 of 4 experimental conditions. (2) Field Study: crossover design.
Sleep laboratory and field settings.
(1) Laboratory Study: 68 healthy in...
To evaluate the dose- response effects of tiagabine on sleep and safety measures in healthy older adults.
Randomized, double-blind, Latin-square design.
Sleep laboratory.
Twenty-four healthy older adults (11 men, 13 women; mean age 68.0 +/- 6.2 years)
Tiagabine 2, 4, or 8 mg, or placebo, each given on two consecutive nights.
Polysomnography reveale...
To assess the effect of 200 mg of modafinil compared to placebo on alertness, neurobehavioral performance, and executive function during 4 consecutive simulated night shifts.
Double-blind, randomized, parallel groups.
Sleep research facility.
32 male and female volunteers between the ages of 18 and 55 years.
200 mg of modafinil or placebo given nig...
Study Objectives
To assess the effect of 200 mg of modafinil compared to placebo on alertness, neurobehavioral performance, and executive function during 4 consecutive simulated night shifts.
Design
Double-blind, randomized, parallel groups.
Setting
Sleep research facility.
Participants
32 male and female volunteers between the ages of 18 and 55...
Intermittent use (i.e., a few nights per week) of hypnotic medication is often recommended for the treatment of chronic insomnia despite an absence of efficacy and safety data using this regimen.
To evaluate the clinical efficacy and safety of intermittent pharmacotherapy for chronic insomnia.
Randomized, double-blind, placebo-controlled, parallel...
Various aspects of human performance were assessed in children after sleep loss.
Sixteen children (7 males, 9 females) between the ages of 10 and 14 years.
Children were randomly assigned to either a control (CTRL) group, with 11 hours in bed, or an experimental sleep restriction (SR) group, with 5 hours in bed, on a single night in the sleep labor...
Study Objectives
Various aspects of human performance were assessed in children after sleep loss.
Participants
Sixteen children (7 males, 9 females) between the ages of 10 and 14 years
Design and Interventions
Children were randomly assigned to either a control (CTRL) group, with 11 hours in bed, or an experimental sleep restriction (SR) group, w...
Includes abstract. Thesis (Ph. D.)--University of Missouri--St. Louis, 2002. Includes bibliographical references (leaves 118-127).
Typescript. Thesis (M.A.)--Psychology, Southern Illinois University at Edwardsville, 1991. Includes bibliographical references (leaves 26-28). Photocopy.