Anestis Gkanogiannis

International Centre for Biosaline Agriculture

Subcellular compartmentalization of metabolic enzymes may elicit specific cellular functions by establishing a unique metabolic environment. Indeed, the nuclear translocation of certain metabolic enzymes is required for epigenetic regulation and gene expression control. Here, we reveal that, in cancer cells, the mitochondrial enzyme methylenetetrah...

Cassava (Manihot esculenta Crantz) is an important staple crop for food security in Africa and South America. The present study describes an integrated genomic and metabolomic approach to the characterization of Latin American cassava germplasm. Classification based on genotyping correlated with the leaf metabolome and indicated a key finding of ad...

Meiotic recombination is a crucial cellular process, being one of the major drivers of evolution and adaptation of species. In plant breeding, crossing is used to introduce genetic variation among individuals and populations. While different approaches to predict recombination rates for different species have been developed, they fail to estimate t...

DNA methylation is the most studied epigenetic trait. It is considered a key factor in regulating plant development and physiology, and has been associated with the regulation of several genomic features, including transposon silencing, regulation of gene expression, and recombination rates. Nonetheless, understanding the relation between DNA methy...

Cassava ( Manihot esculenta Crantz) biofortification with provitamin A carotenoids is an ongoing process that aims to alleviate vitamin A deficiency. The moderate content of provitamin A carotenoids achieved so far limits the contribution to providing adequate dietary vitamin A levels. Strategies to increase carotenoid content focused on genes from...

Motivation Low-coverage next-generation sequencing (LC-NGS) methods can be used to genotype bi-parental populations. This approach allows the creation of highly saturated genetic maps at reasonable cost, precisely localized recombination breakpoints, and minimize mapping intervals for quantitative-trait locus analysis. The main issues with these ge...

This portal (www.cassavagenome.org) is an integrative genome information system that allows centralized access to genomics and genetics data, and analytical tools to facilitate translational and applied research in cassava. As we did previously for the Banana Genome Hub (Droc et al. 2013) and the Coffee Genome Hub (Dereeper et al. 2015), we opted f...

Cultivated cassava diversity has been shaped and is influenced by its wild relatives gene pools. Its primary gene pool (GP-1) consists of the flabellifolia-peruviana subspecies complex that cross easily with domesticated plants. Its secondary gene pool (GP-2) spans Manihot wild species that have a limited ability to interbreed with cassava. RAD seq...

The release of the cassava reference genome by Prochnik et al. in 2012 has allowed cassava geneticists identifying tens of thousands genome-wide sequence variations across multiple cultivars. These genomic variations have helped to develop a new generation of molecular markers for the crop's genetics research either by re-sequencing using restricti...

The South Green Web portal (http://www.southgreen.fr/http://www.southgreen.fr/) provides access to a large panel of public databases, analytical workflows and bioinformatics resources dedicated to the genomics of tropical and Mediterranean crops. The portal contains currently about 20 information systems and tools and targets a broad range of crops...

Background Metagenomics holds great promises for deepening our knowledge of key bacterial driven processes, but metagenome assembly remains problematic, typically resulting in representation biases and discarding significant amounts of non-redundant sequence information. In order to alleviate constraints assembly can impose on downstream analyses,...

A fast and accurate linear supervised algorithm is presented which compares favorably to other state of the art algorithms over several real data collections on the problem of text categorization. Although it has been already presented in [6], no proof of its convergence is given. From the geometric intuition of the algorithm it is evident that it...

This paper describes the participation of the IPL team in the ImageCLEF-2010 campaign. Our research group has participated in the ad hoc task the case-based and the modality tasks of image retrieval based only on textual data. To reach our aim we performed a quantitative evaluation of Lucene search engine using several state of the art similarity f...

A modified and fast to converge Perceptron learning rule algorithm is proposed as a general classification algorithm for linearly separable data. The strategy of the algorithm takes advantage of training errors to successively refine an initial Perceptron Classifier. Original Perceptron learning rule uses training errors along with a parameter α (l...

A novel and efficient learning algorithm is proposed for the binary linear classification problem. The algorithm is trained using the Rocchio's relevance feedback technique and builds a classifier by the intermediate hyperplane of two common tangent hyperplanes for the given category and its complement. Experimental results presented are very encou...

Health information systems on the web basically support the English language. To access high-quality online health information it is frequently a barrier for non-English speakers or speakers of English as a foreign language. In this work we present a cross-language retrieval system to support Greek users in the medical domain, overcome the languag...