Andriy Sirko

Andriy Sirko
Dnepropetrovsk State Medical Academy | DSMA · Department of Neurology and Neurosurgery

PhD, Doctor of Medical Sciences, Associate Professor, Chief of Neurosurgery of Mechnikov Dnipropetrovsk Regional Clinical Hospital

About

111
Publications
1,902
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
26
Citations
Additional affiliations
September 2013 - present
Dnepropetrovsk State Medical Academy
Position
  • Professor
September 2001 - September 2013
Dnipropetrovsk State Medical Academy
Position
  • Research Assistant

Publications

Publications (111)
Article
Herein, we present a clinical case of a successfully staged treatment for a patient with giant hypervascular extra-intracranial metastasis of locally advanced stage IVa T3bN1aM1 (skull) papillary thyroid cancer. To treat the patient, we used tactics that included preoperative endovascular embolization and total microsurgical metastasis removal with...
Article
This report presents a patient with a cerebellar hemangioblastoma associated with obstructive hydrocephalus and a saccular superior cerebellar artery (SCA) aneurysm who was successfully treated using a three-stage approach that included ventriculoperitoneal shunting, preoperative endovascular embolization of the tumor vasculature and aneurysm with...
Article
Full-text available
In this study, we present a rare clinical case of haemangiopericytoma (HPC) of the supra/infratentorial cerebellar tentorium invading the transverse and straight sinuses and the torcular Herophili in a 31-year-old woman. The patient underwent total microsurgical tumour removal (World Health Organisation [WHO] grade II, International Classification...
Article
Introduction The combined use of new types of weapons and new types of personal protective equipment has led to changes in the occurrence, nature, and severity of penetrating brain wounds. The availability of modern equipment, methods of treatment, and trained medical personnel in a civilian hospital, as well as advanced specialty medical care, has...
Article
Full-text available
We present a clinical case of combined tentorial meningioma and cerebellopontine angle epidermoid cyst (EC) in a 33-year-old woman. According to the literature, ours is the fifth case involving a combination of such tumours and the first in which the tumours were located in the posterior cranial fossa. Occurrence of a combination of brain tumours w...
Article
Full-text available
The present study aimed to summarize the literature data about wounds to the dural venous sinus (DVS) and validating the im- portance of surgery in a series of clinical observations in patients with craniocerebral gunshot wound (CGW) sustained in battles with the DVS wound. Materials and methods. We conducted a retrospective analysis of the clinic...
Article
Full-text available
In the present report, a review of the literature on the combination of multiple sclerosis and brain tumours is performed. Additionally, the frequency of such combination, possible etiopathogenetic mechanisms, current diagnostic criteria and treatment approaches are reviewed. Furthermore, the case of a 30-year-old man with multiple sclerosis and an...
Article
Many researchers classify perforating diametric craniocerebral gunshot wounds as fatal because mortality exceeds 96% and the majority of patients with such injuries die before hospitalization. A 23-year-old Ukrainian male soldier was admitted to a regional hospital with a severe perforating craniocerebral wound in a comatose state (Glasgow Coma Sca...
Article
Full-text available
Successful step-by-step treatment of a combined gunshot shrapnel injury of the brain, damaging the left middle cerebral artery (MCA) branches, and penetrating myocardium injury is discussed. Open brain and heart surgeries were performed. A left MCA pseudoaneurysm was formed postoperatively. Endovascular exclusion of the left MCA pseudoaneurysm was...
Article
Full-text available
A clinical study on successful treatment of multifocal brain and spinal cord lesions in neurofibromatosis type 2 in a woman aged 35 years is presented. Magnetic resonance imaging showed bilateral vestibular schwannomas, brain meningiomatosis and multiple spinal intramedullary tumours. The treatment comprised four stages: removal of giant dextral ve...
Article
Full-text available
Here we report the case of a 56-year-old woman who presented with a highly unusual combination of three pathologies, namely a giant left-sided vestibular schwannoma, severe stenosis of the left internal carotid artery, and a right anterior cerebral artery aneurysm. The chosen approach comprised three consecutive surgical procedures, namely (1) aneu...
Article
Full-text available
Glial tumors are the most common primary neoplasms of the central nervous system. Their proportion in the total structure of primary brain tumors is 50-65%. In Ukraine, according to the statistical data of the cancer-registry of the year 2014, 49,3% of patients with primary diagnosed malignant neoplasms of the brain did not live for one year. The a...
Data
Сontralateral acute epidural hematoma (AEDH) after acute subdural hematoma (ASDH) removal is an uncommon, but disastrous postoperative complication. Here we describe six own observations and provide analysis of 42 other cases relating to the above. Сontralateral AEDH after ASDH removal using decompressive craniectomy (DC) is diagnosed in 2.4-4.2% o...
Data
The case of successful treatment of primary brain affection by echinococcus with formation of giant unicameral cyst in patient 28 year-old is documented. Epidemiological data on echinococcosis occurence in the world, in Ukraine, and in Dnipropetrovsk region is specified. Main focus is given to two aspects: preoperative brain echinococcosis diagnosi...
Data
These are the observations of penetrating diagonal gunshot brain wounds. In two injured persons were fragment mine blast wounds, in one — a gunshot head wound. In each case, we described the specifics of diagnostic and treatment strategies and specified their common and distinctive features. 12 stages of surgery were detalized. Full topography of...
Data
These are 7 observations of penetrating gunshot brain wounds with damage to venous sinuses sustained were described. Superior sagittal sinus injuries were most frequent (6 cases). Straight (tentorial) sinus injury occurred in one case. Damage to one or even two sinus walls was observed in 5 cases, 2 cases showed transverse sinus injury which caused...
Data
Найпоширенішим типом поранення на полі бою в умовах локальних збройних конфліктів є множинні рани, спричинені фрагментами вибухового пристрою, які зачіпають множинні анатомічні ділянки [1, 2]. Вогнепальні поранення черепа та головного мозку (ВПЧГМ) під час антитерористичних операцій (АТО) найчастіше (у 90,6% випадків) спричиняються уламками мінно­в...
Data
A metal fragment passed through the left frontal bone causing a penetrating fracture and further through the right and left hemispheres. The metal fragment hit the contralateral inner plate of the frontal bone and rebounded into the brain. Brain injury was also caused by secondary wounding objects such as bone debris that penetrated into the opposi...
Data
Objective: To study the possibility of improvement of response to treatment of injured persons with severe diffuse brain injury (SDBI) through the intracranial pressure (ICP) monitoring and active correction of intracranial hypertension (ICH) with the use of decompressive craniectomy (DC). Material and methods: A prospective analysis of response t...
Data
The article deals with the treatment of patients with traumatic brain injury and acute cerebrovascular accidents. A meta-analysis of clinical studies on the efficacy and safety of L-Lysine Aescinat in these patients is provided. The meta-analysis included results of 12 studies involving 1,728 patients of all age groups, of which 727 persons receive...
Article
Full-text available
Despite the relatively rare occurrence of epidermoid brain tumors (EBT), high rates of postoperative mortality and a high incidence of tumor recurrence are marked in the operated patients. The purpose of research is to improve treatment results of patients with EBT by determining optimal treatment tactic. A retrospective research of 17 patients wit...
Data
This is an observation of a heavy penetrating fragment mine blast brain wound. A fragment passed through the right and left cerebral hemispheres, caused heavy brain injuries, intracranial hematomas, blast skull base fractures and buttonhole vault fractures, falx and intracranial vessels injuries. The entrance wound was located in the left temporal...
Data
Objective. To improve the quality of the first aid delivery in cases of skull and brain gunshot wounds. Materials and methods. Analysis of results of treatment of 790 patients who suffered injuries to various systems and anatomic regions of a body has been performed. Both extent and quality of the medical care at all stages of evacuation of 64 pat...
Data
Purpose. To study features skull and brain of gunshot wounds (SBGW) in local fighting in the East of Ukraine. Material and methods. The results of complex examination and treatment of 790 injured persons been treated in Mechnikov Dnipropetrovsk Regional Clinical Hospital from May 25 to December 31, 2014. SBGW were diagnosed in 64 (8.1%) patients,...
Data
Purpose. To improve the results of surgical treatment in patients with penetrating craniocerebral wounds (PCCW) by implementing optimal treatment strategy considering type of the injury, character of intra- and extracranial injuries. Materials and methods. The results of examination and treatment of 41 injured persons with PCCW wounded in local fi...
Data
Despite the relatively rare occurrence of epidermoid brain tumors (EBT), high rates of postoperative mortality and a high incidence of tumor recurrence are marked relatively among the operated patients. The purpose of research is to improve the results of patients treatment with EBT for determining the optimal treatment tactic. A retrospective rese...
Data
The observation of penetrating cranio-orbital injury by sharp object at fall from a high is presented. The foreign object passed along the right orbit medial wall and penetrated to the middle cranial fossa through the upper palpebral fissure. Further promotion of the object arose damage of cerebellar structures and tentorium with focal intracerebra...
Data
Introduction. Intracranial hypertension (ICH) is a main reason of death and disability in traumatic brain injury (TBI) patients. Study objective is to determine intracranial pressure (ICP) parameters that presumably influence final treatment outcome. Materials and methods. The results of a prospective study of 100 injured persons in the acute pha...
Article
Diagnosis and treatment results of 57 patients with acute diffuse brain injury have been analyzed. Patients were divided into two groups: first study period 2000-2005; second study period 2006-2010. The main differences between the first and the second study periods were in health condition and brain functions monitoring parameters, therapy approac...
Data
Introduction. Surgical treatment of severe penetrating cranio-cerebral trauma (SCCT) is a complex problem. Basal liquorrhea (BL) at skull base fractures causes high risk of purulent-septic complications. Conservative BL treatment at scull base fractures with many splinters sometimes ineffective. Along with intracranial hypertensia elimination at de...
Data
An observation of penetrating traumatic brain injury, made by awl in childhood, followed by remittent nasal liquorrhea and purulent meningoencephalitis for 61 years, is given. For diagnosis clarifying biochemical study of nasal secretion, rhinologic study, MRI and CT-cisternography of the brain were performed. Liquor fistula was closed in two stag...
Data
A prospective study of 16 patients with severe TBI and traumatic brain edema who had undergone decompressive craniectomy (DC) with dura opening was carried out. Directly before surgical intervention and afterwards, TCDG was used to measure blood flow linear velocity (BFLV) in the middle cerebral artery (MCA) in both hemispheres and in extracranial...
Data
2 Введение. Посттравматическую базальную ликворею (ПБЛ) обнаруживают у 2-3% пострадавших при черепно-мозговой травме (ЧМТ). Частота возникновения менингита у пострадавших с посттравматическими ликворными фистулами (ПЛФ) составляет 3-50%. Точность КТ-цистернографии в диагностике ПБЛ от 22 до 100%. Методы. В целях определения эффективности КТ цистерн...
Data
Prospective study of 75 patients with severe brain injury who were conducted intracranial and cerebral perfusion pressure monitoring during decompressive craniectomy. DC with dura opening proved effective therapeutic method for ICP and CPP control. Unilateral wide frontal parieto-temporal craniectomy causes initial ICP value to fall from (39.0±18.1...
Data
We have analyzed the results of medical examination and treatment of 183 patients with acute traumatic intracranial hematomas. Injured persons with heavy traumatic brain injury (GCS score, 4-8) with hematoma volume of over 25 cm3 who were admitted to in-patient department within 72 hours post-injury have been included in our study. In terms of stud...
Data
Prospective study was conducted at 75 injured persons with severe traumatic brain injury, who undergone intracranial pressure (ICP) monitoring during decompressive craniectomy (DC). In the beginning of operation an average ICP was (39±18.1) mm Hg, in the end of surgery performing — (15.8±12.4) mm Hg. DC with dura opening was found to be effective t...
Data
In domestic and foreign literature data about morbidity and prevalence rates of idiopathic normal pressure hydrocephalus (INPH) are absent. This problem is due to lack of clear diagnostic criteria of this nosological form. The publication provides practical recommendations for establishing of INPH clinical diagnosis based on analysis of clinical tr...
Data
100 patients in acute phase of severe brain injury under gone invasive intra cranial pressure (ICP) monitoring. The impact of mean intracranial pressure threshold level on treatment results was studied. Odds ratio (OR) was used to show thein fluence on predicted outcome. With mean ICP value of 15 mmHg, statistically significant differences were fou...
Data
The results of examination and treatment of 114 patients with acute traumatic subdural hematomas were analyzed. There were injured persons with severe traumatic brain injury (Glasgow Coma Scale, 4–8) with hematoma volume of >25 cm3 who were entered the hospital within 72 hours post-injury and who underwent removal of a subdural hematoma have been i...
Data
Late fate of treatment of 75 patients with severe traumatic brain injury who had decompressive craniectomy during acute phase of the injury, were analyzed. A mortality rate within 6 months following the surgery made up 49.3%. Positive treatment result was obtained in 38.7% of patients. Average life quality value among the surviving patients made 73...
Data
Analysis of 84 reconstruction surgeries after decompressive craniectomy (DC) for heavy traumatic brain injury has been done. Sizes of cranial defects varied from 55,8 to 149 mm (mean value, 100,6±16,2 mm). Plastic surgery using autogenous bone which had been stored in mesogastric area of anterior abdominal wall was performed to 35 patients (41,7%)....
Data
Prospective study, in which 84 injured persons with severe cranio-cerebral trauma were included and undergone intracranial pressure monitoring in acute period of trauma, was performed. On the base of Kruskal–Wallis analysis of variance, preoperative factors that affect the intracranial pressure were established. These criteria have to be taken into...
Data
16 cases of application of navigation system Stealth Station® Treon®Plus, Medtroniс (USA) for frameless stereotactic biopsy of brain supratentorial lesion were analyzed. Frameless biopsy technic with our own technological developments is described in details.
Data
We have analyzed the results of treatment of 183 patients with acute traumatic intracranial hematomas. Our study included patients with intracranial hematoma volume of over 25 cm3 who were admitted in comatose state within 72 hours post-injury. In terms of study period, the patients were divided into two groups: first study period, 2000 – 2005; sec...
Data
Prospective study of 100 patients with heavy traumatic brain injury who undergone intracranial pressure invasive monitoring during acute phase of the injury has been done. Based on Kruskal-Wallis analysis of variance, it was found that postoperative ICP value probably affects lethality rates during acute phase of the injury, assessment of impairmen...
Data
Prospective study of 75 patients with heavy traumatic brain injury who undergone intracranial pressure (ICP) monitoring during decompressive craniectomy (DC) for marked brain edema has been done. Mean preoperative ICP made 39±18.1 mm Hg (range of 16 to 82.7), while the postoperative value was as low as 15.8±12.4 mm Hg (range of 2 to 67). DC with du...
Data
Decompressive craniectomy (DC) is widely used for intracranial hypertension treatment after heavy traumatic brain injury (HTBI). Prospective study of 220 patients with HTBI and analysis of literature sources dedicated to DC complications have been done. Decompressive craniectomy is a quite difficult type of neurosurgery. Changes in tissue pressure...
Data
Analysis of results of study of 240 patients with heavy traumatic brain injury (GCS score, 4–8) who were admitted within 72 hours from the moment of traumatic accident has been performed. According to Marshall classifi cation, the patients observed were divided into groups according to their type of diffuse or focal injury. Specifi c clinical and C...
Data
Simultaneous intracranial and cerebral perfusion pressure, and cerebral blood flow monitoring using transcranial dopplerography was performed in 37 patients with severe brain trauma (GCS core of 8 or less). Pearson correlation coefficient was calculated to determine the relation between the variables. It was found that increased intracranial pressu...
Data
Results of treatment of 220 patients with heavy traumatic brain injury (Glasgow Coma S cale score 4 to 8) who undergone decompressive craniectomy during acute trauma period in order to correct intracranial hypertension have been analyzed. 163 patients with acute subdural hematomas and 57 patients with multiple focal brain contusions undergone surge...
Data
Prospective study of 100 patients with heavy traumatic brain injury who undergone intracranial pressure invasive monitoring during acute phase of the injury has been done. Intracranial hypertension (ICP) of over 20 mmHg was registered in 79 % patients with heavy traumatic brain injury. Based on Kruskal — Wallis analysis of variance, it was found th...
Data
Prospective study of 100 patients with heavy traumatic brain injury who undergone intracranial pressure monitoring during acute phase of the injury has been done. Based on Kruskal — Wallis analysis of variance, preoperative factors which aff ect postoperative intracranial pressure have been established. Postoperative ICP correlates with following p...
Data
Materials of open randomized study of L-lizin escinat® efficacy are presented. The results of clinical study showed, that L-lizin escinat® used in dose 10 ml twice a day intravenously promotes statistically decreasing of expressed intracranial hypertension in injured persons with severe cranio-cerebral trauma.
Data
The observation of penetrable severe skull base trauma caused by the circle of angle grinder is described. Bifrontal decompressive craniectomy was performed, corpus alien and bone shallow fragments were extracted, skull base plastics was performed using patient’s tissues.
Data
Publications and clinical trials, devoted to decompressive craniectomy (DC), performing in treatment of injured persons with severe cranio-cerebral trauma were analyzed. Main attention was paid to literature issues studying, devoted to researches, based on principals of evidence medicine. Pathophysiology mechanisms, indications, surgical techniques...
Data
The experience of complex treatment of 13 patients with AIDS-associated focal brain lesion is given. In all cases diagnosis was confirmed by brain biopsy. Minimally invasive stereotactic methods allowed to identify clearly and with minimal damage the nature of focal brain lesion at patients with HIV/AIDS and to use differentiated treatment.
Data
In our days stereotactic technologies take an important place in brain tumors treatment. The analysis of stereotactic neurosurgery development and it’s role increasing in neurooncology is given. A search in data base MEDLINE between 1966–2008 years with annual tendencies analysis was done.
Data
A case of sellar chordoma, combined with inborn frontal sinus abnormality at 36 years old man, is given. Tumor was removed using transseptal transsphenoidal approach under neuronavigation control. The diagnosis was verified on the base of data of histological and immunohistochemical tumor research.
Data
Представлены материалы открытого рандомизированного исследования по изучению эффективности препарата L-лизина эсцинат®. Результаты клинических испытаний позволяют сделать вывод, что L-лизина эсцинат® способствует статистически значимому уменьшению выраженности внутричерепной гипертензии у пациентов с тяжелой черепно-мозговой травмой при использован...
Data
The initial experience of Stealth Station® TREON®Plus navigation system (Medtronic, USA) and local fibrinolysis with aktilyze during operation because of primary non-traumatic deep intracranial hemorrhages was analyzed. 12 patients were operated using thas method. Techniques of imageguided aspiration and local fibrinolysis according to protocol wer...
Data
Today active searches of effective method of malignant brain tumors treatment of that would be able to provide not only substantial increase of patients’ life-span but also improvement of it’s quality. Among radiation therapy methods brachytherapy occupies a separate place. The idea of radio-active sources delivery directly to the tumour looks prom...